Abstract: The present invention is directed generally to activating gene expression or causing over-expression of a gene by recombination methods in situ. The invention also is directed generally to methods for expressing an endogenous gene in a cell at levels higher than those normally found in the cell. In one embodiment of the invention, expression of an endogenous gene is activated or increased following integration into the cell, by non-homologous or illegitimate recombination, of a regulatory sequence that activates expression of the gene. The invention also provides methods for the identification, activation, isolation, and/or expression of genes undiscoverable by current methods since no target sequence is necessary for integration. Thus, by the present invention, endogenous genes, including those associated with human disease and development, may be activated and isolated without prior knowledge of the sequence, structure, function, or expression profile of the genes.

Abstract: The present invention is directed generally to activating gene expression or causing over-expression of a gene by recombination methods in situ. The invention also is directed generally to methods for expressing an endogenous gene in a cell at levels higher than those normally found in the cell. In one embodiment of the invention, expression of an endogenous gene is activated or increased following integration into the cell, by non-homologous or illegitimate recombination, of a regulatory sequence that activates expression of the gene. The invention also provides methods for the identification, activation, isolation, and/or expression of genes undiscoverable by current methods since no target sequence is necessary for integration. Thus, by the present invention, endogenous genes, including those associated with human disease and development, may be activated and isolated without prior knowledge of the sequence, structure, function, or expression profile of the genes.

Abstract: Herpes is treated by administering a smallpox vaccination and by repeatedly administering the vaccination after waiting a scab, formed after a blister at the vaccination site, falls off, with the treatment being completed when the blister and scab fail to form.

Abstract: A method of improving retention and drainage in a papermaking process is disclosed. The method provides for the addition of an associative polymer, starch or a starch derivative and optionally a siliceous material to the papermaking slurry. Additionally, a composition comprising an associative polymer and starch or starch derivative and optionally further comprising cellulose fiber is disclosed.

Abstract: A method of making a Web-DVD which integrates computer-based content, such as Web links/HTML content or images, with DVD-Video content by using a graphical user interface (GUI) is disclosed. The method provides a software application that allows a developer to add highly integrated computer-based content, such as, but not limited to, HTML content such as Web site links and images, PDF files and/or Power Point files, to a predetermined DVD-Video content with the developer using the GUI to create a Web-DVD instead of using complex JavaScript or HTML commands or programming language. The software application writes a series of DVD-ROM files, based on the developer's selection, e.g., “point and click,” of the GUI options, that create an interaction between the DVD-Video content and the computer-based content or HTML content.

Abstract: The present invention describes polymeric retention and drainage aids for cellulosic fiber compositions and methods of use of the same.

Abstract: A method of improving retention and drainage in a papermaking process is disclosed. The method provides for the addition of an associative polymer, a water compatible polymer and optionally a siliceous material to the papermaking slurry. Additionally, a composition comprising an associative polymer, and a water compatible polymer and optionally further comprising cellulose fiber is disclosed.

Abstract: A method of improving retention and drainage in a papermaking process is disclosed. The addition of an associative polymer, a poly(vinylamine) and optionally a siliceous material to the papermaking slurry to improve retention and drainage is disclosed. Additionally a method to improve retention and drainage comprising addition of an organic microparticle, a poly(vinylamine) and optionally a siliceous material to the papermaking slurry is disclosed. A composition comprising an associative polymer, and a poly(vinylamine) and optionally further comprising cellulose fiber is disclosed.

Abstract: A method of improving retention and drainage in a papermaking process is disclosed. The method provides for the addition of an associative polymer, a microparticle and optionally a siliceous material to a papermaking slurry. Additionally, a composition comprising an associative polymer and a microparticle and optionally further comprising cellulose fiber is disclosed.

Abstract: A method of improving retention and drainage in a papermaking process is disclosed. The method provides for the addition of an associative polymer, a polyelectrolyte and optionally a siliceous material to the papermaking slurry. Additionally, a composition comprising an associative polymer, and a polyelectrolyte and optionally further comprising cellulose fiber is disclosed.

Abstract: The present invention is directed generally to activating gene expression or causing over-expression of a gene by recombination methods in situ. The invention also is directed generally to methods for expressing an endogenous gene in a cell at levels higher than those normally found in the cell. In one embodiment of the invention, expression of an endogenous gene is activated or increased following integration into the cell, by non-homologous or illegitimate recombination, of a regulatory sequence that activates expression of the gene. The invention also provides methods for the identification, activation, isolation, and/or expression of genes undiscoverable by current methods since no target sequence is necessary for integration. The invention is specifically directed to methods of drug discovery using the activated gene products for compound testing.

Abstract: The invention relates to the field of gene therapy, gene expression, and vectors for these uses. In particular, the invention relates to the development and use of an artificial or synthetic chromosome for gene expression and gene therapy in mammals, and especially humans. The invention allows the controlled construction of stable synthetic or artificial chromosomes constructed from isolated segments of purified DNA. Functional minimal segments preferably include centromeric DNA, telomeric DNA, and genomic DNA. The artificial chromosome performs the essential chromosomal functions of naturally-occurring chromosomes so as to permit the chromosome to function as an effective vector for gene therapy.

Abstract: A method to invert an inverse emulsion water compatible polymer product using a combination of surfactants that have specific chemical structures is disclosed. A combination, or blend, of two or more surfactants provides for an effective breaker system. The blend of surfactants is more effective than the individual surfactants.

Abstract: Step 1. Method of treating disease: this procedure must be done by a certified Medical Doctor, who has access to controlled substances. Doctor is to give patient one normal smallpox vaccination. Do not touch or itch the blister it causes, and when the blister scabs, continue not to touch. Wait until the scab naturally falls off, return to same Doctor as soon as possible to repeat Step 1. within 24 to 48 hours, it is imperative. Repeat process over and over, each time the process is done, the blister and scab gets smaller and smaller until the process is done, and there is no visible blister or scab. This may take 4 to 6 weeks for process to be complete; process longer in severe cases. To save on scaring it is recommended to vaccinate patients on the same site where original childhood smallpox vaccination was administered. This is the total complete cure to the Herpes Virus. Patient becomes immune to the virus. Virus is contagious until the GRACE PROCESS is complete.

Abstract: A temperature control system for reducing flicker in an electrical resistance heater comprising: an electrical resistance heater divided into at least two electrical loads and; a source of electrical power for repetitively supplying electrical power to each of the at least two electrical loads at successive different time sub periods within a predetermined time period, wherein the sum of the power supplied to the at least two electrical loads is equal to the total power supplied to the electrical resistance heater during the predetermined time period.

Abstract: A temperature control system for reducing flicker in an electrical resistance heater comprising: an electrical resistance heater divided into at least two electrical loads and; a source of electrical power for repetitively supplying electrical power to each of the at least two electrical loads at successive different time sub periods within a predetermined time period, wherein the sum of the power supplied to the at least two electrical loads is equal to the total power supplied to the electrical resistance heater during the predetermined time period.

Abstract: A temperature controlled apparatus comprising: an object having a surface and being rotatable about an axis; an electrical heater assembly thermally coupled to the surface of the object; a temperature sensor assembly mounted on the object for sensing the temperature of the object surface and for producing temperature signals representative of the sensed temperatures; a microprocessor non-rotatably mounted with respect to the rotatable object; an optical communication link for transmitting the temperature signal to the microprocessor; and a temperature control assembly, non-rotatably mounted with respect to the rotatable object for controlling the flow of electrical power to the heater in response to control signals from the microprocessor as a function of the transmitted temperature signals.

Abstract: A translator for converting items of interactive program guide data to data structures that are more universal to handle with popular platforms, operating systems, tools, utilities and other hardware and software processors and resources. The invention uses C++ class objects and structures. The objects and structures are placed into a Common Object Request Broker Architecture (CORBA) “wrapper.” This allows the objects to be handled by platform-independent interfaces so that the system is easily adaptable to different hardware devices and software functionality. Aspects of the invention include the translation from custom IPG formats to CORBA-wrapped C++ objects, the storage of the objects, transmission of the objects among devices, and data entry and error handling of information represented by the objects.

Abstract: An water based adhesive useful for bottle labeling applications. The adhesive contains styrene maleic anhydride and rosin, and provides a formulation with alkali sensitivity at moderate temperature together with cold water resistance.

Abstract: An water based adhesive useful for bottle labeling applications. The adhesive contains styrene maleic anhydride and rosin, and provides a formulation with alkali sensitivity at moderate temperature together with cold water resistance.