Patents by Inventor John Heyman

John Heyman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250215485
    Abstract: The present invention generally relates to microfluidics and labeled nucleic acids. Certain aspects are generally directed to containing cells in gels, such as agarose gels, and determining nucleic acids within the cells, e.g., while contained within the gels. The nucleic acids may be, for example, genomic DNA, mRNA, transcriptomes, or the like. In some embodiments, for instance, both genomic DNA and RNA (e.g., as in a transcriptome) from a cell may be determined. In some cases, the nucleic acids may be attached to beads for sequencing or other purposes. Such systems may be useful, for example, for high-throughput sequencing or other applications.
    Type: Application
    Filed: October 24, 2022
    Publication date: July 3, 2025
    Applicant: President and Fellows of Harvard College
    Inventors: David A. Weitz, Huidan Zhang, John Heyman
  • Patent number: 12336549
    Abstract: Systems and methods have demonstrated the capability of rapidly cooling the contents of pods containing the ingredients for food and drinks.
    Type: Grant
    Filed: November 17, 2022
    Date of Patent: June 24, 2025
    Assignee: ColdSnap, Corp.
    Inventors: Matthew Fonte, John Heymans, Nicholas Fonte, Robert Devaney, Vincent Weaver, Benjamin Fichera
  • Patent number: 12296045
    Abstract: The present invention generally relates to polymers and, in particular, to copolymers for stabilizing, e.g., emulsions or droplets. In certain aspects, the copolymers may comprise a relatively hydrophobic monomer and a relatively hydrophilic monomer polymerized together (e.g., randomly) to form the copolymer. Examples of hydrophobic monomers include methacrylates and vinylphenyls; examples of hydrophilic monomers include boronic acids or acid derivatives. Surprisingly, such random copolymers may act as surfactants, e.g., stabilizing droplets within the emulsion. In addition, in some cases, an interfacial film may be produced by exposing the copolymer to a complexing molecule, such as a polyol, that can complex with the copolymer to form the film. In some cases, the film may at least partially surround a droplet, and in certain embodiments, the film may be sufficiently sturdy such that the droplet can be removed from the emulsion.
    Type: Grant
    Filed: May 22, 2020
    Date of Patent: May 13, 2025
    Assignee: President and Fellows of Harvard College
    Inventors: David A. Weitz, Joerg G. Werner, Julie V. Brouchon, John Heyman, Brendan Deveney
  • Publication number: 20250031715
    Abstract: Some pods include a body having a sidewall that extends from a first end of the body to a second end of the body to define an interior of the pod. The pod contains ingredients disposed within the interior of the pod for producing a single serving of a cooled food or drink. The pod includes a base attached to the first end of the pod. The base includes a rim with at least one radially-inward facing detent. At least a portion of the base is removable for dispensing the produced cooled food or drink from the pod. The pod includes a cap including a shearing drive including a track or circumscribed feature sized to engage the at least one radially-inward facing detent to snap the shearing drive to the base of the pod.
    Type: Application
    Filed: July 26, 2024
    Publication date: January 30, 2025
    Inventors: John Heymans, Dong Hua
  • Publication number: 20240182234
    Abstract: Systems and methods have demonstrated the capability of rapidly cooling the contents of pods containing the ingredients for food and drinks.
    Type: Application
    Filed: February 15, 2024
    Publication date: June 6, 2024
    Inventors: Matthew Fonte, Robert Devaney, John Heymans, Nicholas Fonte, Benjamin Fichera
  • Patent number: 11939144
    Abstract: Systems and methods have demonstrated the capability of rapidly cooling the contents of pods containing the ingredients for food and drinks.
    Type: Grant
    Filed: February 23, 2023
    Date of Patent: March 26, 2024
    Assignee: ColdSnap, Corp.
    Inventors: Matthew Fonte, Robert Devaney, John Heymans, Nicholas Fonte, Kevin Stillerman, Benjamin Fichera
  • Publication number: 20240077250
    Abstract: Systems and methods have demonstrated the capability of rapidly cooling the contents of pods containing the ingredients for food and drinks.
    Type: Application
    Filed: November 13, 2023
    Publication date: March 7, 2024
    Inventors: Matthew Fonte, John Heymans, Nicholas Fonte, Benjamin Fichera
  • Publication number: 20240043893
    Abstract: The present invention generally relates to microfluidics and labeled nucleic acids. For example, certain aspects are generally directed to systems and methods for labeling nucleic acids within microfluidic droplets or other compartments, for instance, arising from a cell. In one set of embodiments, particles may be prepared containing oligonucleotides that can be used to determine target nucleic acids, e.g., attached to the surface of the particles. The oligonucleotides may include “barcodes” or unique sequences that can be used to distinguish nucleic acids in a droplet from those in another droplet, for instance, even after the nucleic acids are pooled together or removed from the droplets. Certain embodiments of the invention are generally directed to systems and methods for attaching additional or arbitrary sequences to the nucleic acids within microfluidic droplets or other compartments, e.g.
    Type: Application
    Filed: July 14, 2023
    Publication date: February 8, 2024
    Applicant: President and Fellows of Harvard College
    Inventors: David A. Weitz, Huidan Zhang, John Heyman, Allon Moshe Klein
  • Patent number: 11846466
    Abstract: Systems and methods have demonstrated the capability of rapidly cooling the contents of pods containing the ingredients for food and drinks.
    Type: Grant
    Filed: September 24, 2020
    Date of Patent: December 19, 2023
    Assignee: ColdSnap, Corp.
    Inventors: Matthew Fonte, Robert Devaney, John Heymans, Nicholas Fonte, Benjamin Fichera, Ian McGinty, Jason Hugenroth, Max Louis Lemoine, Daniel Ross Stelly
  • Patent number: 11746367
    Abstract: The present invention generally relates to microfluidics and labeled nucleic acids. In one aspect, the present invention is generally directed to a method, wherein the method includes providing a plurality of droplets comprising particles, the particles comprising oligonucleotides, and attaching a nucleic acid sequence to the oligonucleotides. Certain embodiments are generally directed to systems and methods for splitting a droplet into two or more droplets. Certain embodiments are generally directed to systems and methods for sorting fluidic droplets in a liquid.
    Type: Grant
    Filed: April 15, 2016
    Date of Patent: September 5, 2023
    Assignee: President and Fellows of Harvard College
    Inventors: David A. Weitz, Huidan Zhang, John Heyman, Allon Moshe Klein
  • Publication number: 20230192392
    Abstract: Systems and methods have demonstrated the capability of rapidly cooling the contents of pods containing the ingredients for food and drinks.
    Type: Application
    Filed: February 23, 2023
    Publication date: June 22, 2023
    Inventors: Matthew Fonte, Robert Devaney, John Heymans, Nicholas Fonte, Kevin Stillerman, Benjamin Fichera
  • Publication number: 20230150756
    Abstract: Systems and methods have demonstrated the capability of rapidly cooling the contents of pods containing the ingredients for food and drinks.
    Type: Application
    Filed: November 15, 2022
    Publication date: May 18, 2023
    Inventors: John Heymans, Benjamin Fichera, Nicholas Fonte, Jonathan Watson, James Lynch, Dong Hua, Richard Bernard Streeter, Samuel D. J. Brown, George Nieves, SR., Kevin Stillerman, Mehmet H. Duymazlar, Matthew Fonte
  • Patent number: 11627747
    Abstract: Systems and methods have demonstrated the capability of rapidly cooling the contents of pods containing the ingredients for food and drinks.
    Type: Grant
    Filed: September 19, 2022
    Date of Patent: April 18, 2023
    Assignee: ColdSnap, Corp.
    Inventors: Matthew Fonte, John Heymans, Benjamin Fichera, Nicholas Fonte
  • Patent number: 11608223
    Abstract: Systems and methods have demonstrated the capability of rapidly cooling the contents of pods containing the ingredients for food and drinks.
    Type: Grant
    Filed: September 19, 2022
    Date of Patent: March 21, 2023
    Assignee: ColdSnap, Corp.
    Inventors: Matthew Fonte, Robert Devaney, John Heymans, Nicholas Fonte, Kevin Stillerman, Benjamin Fichera
  • Publication number: 20230078711
    Abstract: Systems and methods have demonstrated the capability of rapidly cooling the contents of pods containing the ingredients for food and drinks.
    Type: Application
    Filed: November 17, 2022
    Publication date: March 16, 2023
    Inventors: Matthew Fonte, John Heymans, Nicholas Fonte, Robert Devaney, Vincent Weaver, Benjamin Fichera
  • Patent number: 11564402
    Abstract: Systems and methods have demonstrated the capability of rapidly cooling the contents of pods containing the ingredients for food and drinks.
    Type: Grant
    Filed: August 26, 2022
    Date of Patent: January 31, 2023
    Assignee: ColdSnap, Corp.
    Inventors: Matthew Fonte, John Heymans, Benjamin Fichera, Jason Hugenroth
  • Publication number: 20230013226
    Abstract: Systems and methods have demonstrated the capability of rapidly cooling the contents of pods containing the ingredients for food and drinks.
    Type: Application
    Filed: September 19, 2022
    Publication date: January 19, 2023
    Inventors: Matthew Fonte, Robert Devaney, John Heymans, Nicholas Fonte, Kevin Stillerman, Benjamin Fichera
  • Publication number: 20230016913
    Abstract: Systems and methods have demonstrated the capability of rapidly cooling the contents of pods containing the ingredients for food and drinks.
    Type: Application
    Filed: September 19, 2022
    Publication date: January 19, 2023
    Inventors: Matthew Fonte, John Heymans, Benjamin Fichera, Nicholas Fonte
  • Publication number: 20230000104
    Abstract: Systems and methods have demonstrated the capability of rapidly cooling the contents of pods containing the ingredients for food and drinks.
    Type: Application
    Filed: August 26, 2022
    Publication date: January 5, 2023
    Inventors: Matthew Fonte, John Heymans, Benjamin Fichera, Jason Hugenroth
  • Patent number: 11503841
    Abstract: Systems and methods have demonstrated the capability of rapidly cooling the contents of pods containing the ingredients for food and drinks.
    Type: Grant
    Filed: May 20, 2022
    Date of Patent: November 22, 2022
    Assignee: ColdSnap, Corp.
    Inventors: Matthew Fonte, John Heymans, Nicholas Fonte, Benjamin Fichera