Abstract: The invention provides novel peptide prodrugs that contain cleavage sites specifically cleaved by human kallikrein 2 (hK2). These prodrugs are useful for substantially inhibiting the non-specific toxicity of a variety of therapeutic drugs. Upon cleavage of the prodrug by hK2, the therapeutic drugs are activated and exert their toxicity. Methods for treating cell proliferative disorders are also featured in the invention.

Abstract: The invention provides novel peptide prodrugs that contain cleavage sites specifically cleaved by human kallikrein 2 (hK2). These prodrugs are useful for substantially inhibiting the non-specific toxicity of a variety of therapeutic drugs. Upon cleavage of the prodrug by hK2, the therapeutic drugs are activated and exert their toxicity. Methods for treating cell proliferative disorders are also featured in the invention.

Abstract: An apparatus and method is provided for treating a waste material, particularly an aqueous waste material containing fats, oils and greases (FOG), involving the use of at least two stages in which, in the first stage, the aqueous waste material is subjected to a separation step in which water is removed to leave a partially refined stream containing the FOG followed by a second treatment stage, in which the partially refined FOG stream is further refined by removing more of the water so as to produce a FOG-containing stream that has a low water content which can be used as a fuel. In one embodiment, the refined FOG is used as a fuel for a combustion engine, typically a hydrogen assisted combustion engine for generating electricity. The energy generating plant can be combined with the waste treatment plant or the two can be separated from each other.

Abstract: The isolation and characterization of a metastasis tumor suppressor gene KAI1 is disclosed and diagnostic methods and gene therapy approaches utilizing reagents derived from the nucleotide and deduced amino acid sequences of the KAI1 gene are provided.

Abstract: Use of an aglycosylated antibody having a binding affinity for the CD3 antigen complex is provided for the manufacture of a medicament for treatment of chronic joint inflammation, and more particularly for treating Rheumatoid Arthritis.

Abstract: A real-time request matching system for and method of matching free-format requests of users, as requestors, to providers in servicing the requests, each of the requesters having at least one communicator for making requests and addressing replies thereto and each of the providers having at least one communicator for addressing requests and respective replies thereto, the method comprising the steps of: receiving requests from requestors; for each request, providing for the request to be relayed to selected providers as addressed thereby; receiving replies from selected providers, the replies received being made by the respective providers based on the respective requests; and one or both of supplying, for each request, information regarding the respective requestor to any providers having provided a positive reply to the respective request, with a positive reply indicating that a provider is able to meet a request, and information regarding replies from selected providers to the respective request to the res

Abstract: The present invention relates to a real-time, ride-share request matching system for and method of matching persons registered as lift requirers and requiring a lift to persons registered as lift providers and available to consider providing lifts such as to enable sharing of vehicle journeys, each of the lift requirers having a mobile communicator for making lift requests and each of the lift providers having a mobile communicator for addressing lift requests, the method comprising the steps of: receiving lift requests, each including a voice message, from lift requirers; relaying lift requests to respective lift providers as determined by the locations of the respective lift requirers; and receiving replies from lift providers to respective lift requests in accepting the same.

Abstract: A system, method, and program for managing users, groups, servers, and resources in a heterogeneous network environment are disclosed. The network environment includes a configuration server coupled to a number of deployment servers, which each operates under a specific platform. In response to receipt of a generic command for management of a user, group, server, or resource by the configuration server, a determination is made based on pre-assignment as to which one of the deployment servers is the appropriate deployment server that is to receive the generic command. The generic command is mapped to a specific-platform command executable under the respective specific platform of the appropriate deployment server. The specific-platform command is executed by the appropriate deployment server to complete a task for performing the generic command. In a preferred embodiment, a set of generic commands for managing the users, groups, servers, and resources in the heterogeneous networked environment is defined.

Abstract: A method which allows a user through a portable device to print documents which are remotely stored is disclosed. The user designates a first document among the documents to be printed as an instruction in a portable device. Such an instruction is sent from the portable device to a local printer via a portable device communication port in the local printer, where it is further passed to a host computer connected to the local printer and capable of accessing the documents. According to the instruction, the host computer retrieves the first document and subsequently prints out the retrieved first document on the local printer.

Abstract: A method for transferring data across a firewall is provided. According to the invention, a host computer which can access the data sends a poll periodically to a target computer for a presence of a data transfer instruction in the target computer. If the data transfer instruction is present in the target computer, in response to the poll, the target computer sends a response to the host computer to inform the host computer of at least part of the instruction. Based on the response from the target computer, the host computer transmits the data across the firewall to the target computer according to the part of the instruction.

Abstract: A method for transferring one of a plurality of data stored in a sub-computer system to a target computer system using a mobile device is provided. In such a method, the mobile device initiates the process by sending instructions to a central computer system via a first network. The instructions designate a first piece of data to be transmitted as well as the target computer system to which the first piece of data is to be transmitted. According to the instructions, the central computer system retrieves the designated first piece of data from the sub-computer system. The first piece of data then is transmitted from the central computer system to the target computer system.

Abstract: A method and apparatus for applying information stored remotely to an appliance via a mobile device are provided. The mobile device initiates the process by transmitting instructions to a computer system via a communication network. The instructions designate the information to be processed as well as the appliance to which the information is to be applied. According to the instructions, the computer system retrieves the information and converts the information to a document suitable for the appliance. The computer system then applies the document to the designated appliance.

Abstract: A method and apparatus for applying information stored remotely to an appliance via a mobile device are provided. The mobile device initiates the process by transmitting instructions to a computer system via a communication network. The instructions designate the information to be processed as well as the appliance to which the information is to be applied. According to the instructions, the computer system retrieves the information and converts the information to a document suitable for the appliance. The computer system then applies the document to the designated appliance.

Abstract: A method and apparatus for supplying information stored remotely to an appliance via a mobile device are provided. A client computer extracts the network path bookmark information from a predetermined directory in the client computer, and transmits the network path bookmark information to a server computer via a first communication network. The mobile device, which is connected to the server computer via a second communication network, requests the at least one network path bookmark information, and the server computer transmits the requests network path bookmark information to the mobile device. The mobile device then initiates the process by sending instructions to a computer system via a network. The instructions designate information to be processed using at least one bookmark as well as the appliance to which the information is to be applied. According to the instructions, the information is retrieved and converted to a document format suitable for the appliance.

Abstract: A method and apparatus for applying information stored remotely to an appliance via a mobile device are provided. The mobile device initiates the process by sending instructions to a computer system via a network. The instructions designate a first piece of information to be processed as well as the appliance to which the information is to be applied. According to the instructions, the computer system retrieves the first piece of information and converts the information to a document suitable for the appliance. The computer system then applies the document to the designated appliance.

Abstract: A method of treating prostate cancer by co-administering a tyrosine kinase inhibitor such as an indolocarbazole and a chemical castration agent is disclosed. A composition containing a tyrosine kinase inhibitor and a chemical castration agent is also disclosed.