Patents by Inventor John J. Allen

John J. Allen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240409557
    Abstract: The present disclosure provides novel 15-hydroxy-prostaglandin dehydrogenase inhibitors, pharmaceutical compositions comprising such compounds, and methods of using such compounds and compositions in treating 15-hydroxy-prostaglandin dehydrogenase-mediated disease. Also provided are methods of making such compounds and intermediates thereof. The compounds have a general Formula (A). Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula (A).
    Type: Application
    Filed: May 7, 2024
    Publication date: December 12, 2024
    Applicant: AMGEN INC.
    Inventors: Kevin Lloyd GREENMAN, Alexander J. Pickrell, Kexue LI, Albert K. AMEGADZIE, Hui-Ling WANG, Nicholas Anthony WEIRES, John G. ALLEN, Matthew P. BOURBEAU
  • Patent number: 12158325
    Abstract: Switchless sensing is provided to control electronic devices of the type associated with deterrent devices.
    Type: Grant
    Filed: October 9, 2023
    Date of Patent: December 3, 2024
    Assignee: Crosman Corporation
    Inventors: Jeffrey W. Mock, John A. Kowalczyk, Jr., Eric A. St. Phillips, Christopher A. Gagliano, Michael W. Allen, Robert J MacBlane
  • Publication number: 20240390989
    Abstract: A tool bit including a tip configured to engage a work surface, a shank extending from the tip and defining a longitudinal axis, and a drive portion coupled to an end of the shank opposite from the tip and configured to be engaged by a tool, wherein the drive portion includes a plurality of splines circumferentially spaced around the longitudinal axis, each spline having opposing sidewalls which extend through the drive portion
    Type: Application
    Filed: October 20, 2022
    Publication date: November 28, 2024
    Inventors: Kyle Reeder, James Wekwert, Jeremy R. Ebner, Troy C. Thorson, Jacob P. Schneider, Douglas W. Allen, James J. Van Essen, Ian H.A. Blair, John J. Springer
  • Patent number: 12144983
    Abstract: A cardiac lead system is provided. The lead is placed epicardially through the transverse pericardial sinus with integrated curvatures to prevent the lead from slipping out of the transverse pericardial sinus. Interaction with multiple chambers of the heart is facilitated in a single lead, without anchors that embed into the heart wall. Multiple electrodes can be grouped over each targeted heart area to ensure adequate electrical contact.
    Type: Grant
    Filed: May 20, 2020
    Date of Patent: November 19, 2024
    Inventors: Venkatakrishna N. Tholakanahalli, Andy C. Pfahnl, John J. Allen
  • Publication number: 20240335290
    Abstract: A pump is connected between penile cylinder(s) and a reservoir of a prosthesis. A squeezing pressure applied to the penile cylinder moves a first liquid volume out of the cylinder and into a first chamber of the pump, which displaces a piston inside of the pump. Displacement of the piston creates a vacuum space (a second chamber) between the piston and the housing of the pump, and a second liquid volume is drawn out of the reservoir and into the vacuum space. A return spring pushes the piston back to its starting position, which pushes both the first liquid volume and the second liquid volume out of the pump and into the penile cylinders.
    Type: Application
    Filed: June 14, 2024
    Publication date: October 10, 2024
    Inventors: Frederick William Hamlin, Anna Christina Miller, John J. Allen
  • Publication number: 20240327461
    Abstract: The invention provides modified apelin polypeptides having increased stability, circulating half-life, and/or potency relative to the native apelin-13 polypeptide. Compositions comprising the modified apelin polypeptides and methods of using the polypeptides for treating cardiac disorders, such as heart failure, are also disclosed.
    Type: Application
    Filed: June 11, 2024
    Publication date: October 3, 2024
    Applicant: AMGEN INC.
    Inventors: Jerry Ryan HOLDER, Gayathri SWAMINATH, Michael J. FROHN, Brian Alan LANMAN, Anthony B. REED, Leslie P. MIRANDA, John Gordon ALLEN, Alexander J. PICKRELL, Aaron C. SIEGMUND, Lewis D. PENNINGTON, Bryant YANG
  • Patent number: 12097050
    Abstract: Methods and systems for image segmentation and analysis are described. A predictive model may be trained to identify and/or extract a rich set of image features with extensive prognostic value. For example, the predictive model may be trained to identify and/or extract features that that may be visualized to identify areas of interest (e.g., high-risk regions, etc.) within or adjacent to an object of interest, such a tumor. The predictive model may be trained to identify and/or extract features that that may predict a health related outcome, such as cancer patient survival/death, and modify therapeutic outcomes, such as diagnosis and treatment.
    Type: Grant
    Filed: February 27, 2020
    Date of Patent: September 24, 2024
    Assignee: UNIVERSITY OF IOWA RESEARCH FOUNDATION
    Inventors: Stephen Baek, Yusen He, Xiaodong Wu, Yusung Kim, Bryan G. Allen, John Buatti, Brian J. Smith
  • Patent number: 12083121
    Abstract: Provided herein are KRAS G12C inhibitors, such as composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.
    Type: Grant
    Filed: January 19, 2022
    Date of Patent: September 10, 2024
    Assignee: Amgen Inc.
    Inventors: John Gordon Allen, Brian Alan Lanman, Jian Chen, Anthony B. Reed, Victor J. Cee, Longbin Liu, Patricia Lopez, Ryan Paul Wurz, Thomas T. Nguyen, Shon Booker, Jennifer Rebecca Allen, Margaret Chu-Moyer, Albert Amegadzie, Ning Chen, Clifford Goodman, Jonathan D. Low, Vu Van Ma, Ana Elena Minatti, Nobuko Nishimura, Alexander J. Pickrell, Hui-Ling Wang, Youngsook Shin, Aaron C. Siegmund, Kevin C. Yang, Nuria A. Tamayo, Mary Walton, Qiufen Xue
  • Patent number: 12064329
    Abstract: An implant and suture locking system is provided. The implant can include a lateral or distal anchor, and a medial or proximal anchor. One or more suture loops can extend between and operatively connect the anchors. A medial suture loop can extend through apertures in the medial anchor to provide efficient and easily adjustable tensioning and suture locking for the implant.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: August 20, 2024
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: John J. Allen, Andreas C. Pfahnl, Jason R. Gerold
  • Patent number: 12036124
    Abstract: A pump is connected between penile cylinder(s) and a reservoir of a prosthesis. A squeezing pressure applied to the penile cylinder moves a first liquid volume out of the cylinder and into a first chamber of the pump, which displaces a piston inside of the pump. Displacement of the piston creates a vacuum space (a second chamber) between the piston and the housing of the pump, and a second liquid volume is drawn out of the reservoir and into the vacuum space. A return spring pushes the piston back to its starting position, which pushes both the first liquid volume and the second liquid volume out of the pump and into the penile cylinders.
    Type: Grant
    Filed: February 8, 2022
    Date of Patent: July 16, 2024
    Assignee: Coloplast A/S
    Inventors: Frederick William Hamlin, Anna Christina Miller, John J. Allen
  • Publication number: 20240197312
    Abstract: A method of preparing a suture fixation device for use in surgery to treat pelvic organ prolapse includes providing a delivery device and a tissue fixation device. The tissue fixation device includes a tab connected to a tissue anchor, with the tissue anchor having a suture eyelet. The method includes instructing a user to hold the tab and insert the tissue anchor into the delivery device and breaking the tab away from the tissue anchor leaving the tissue anchor in the delivery device.
    Type: Application
    Filed: February 28, 2024
    Publication date: June 20, 2024
    Inventors: John J. Allen, John Clegg, William Hartsig, Peter Meinz, Mark A. Moschel, Sarah J. Schuchardt, Neal Poucher
  • Patent number: 11944288
    Abstract: A tissue anchor system includes a fixation device and a tool. The fixation device includes a tab connected to a tissue anchor. The tool includes a shaft connected between a proximal handle portion and a distal tip. The distal tip is configured to limit movement of the fixation device during loading of the tissue anchor.
    Type: Grant
    Filed: April 28, 2021
    Date of Patent: April 2, 2024
    Assignee: Coloplast A/S
    Inventors: John J. Allen, John Clegg, William Hartsig, Peter Meinz, Mark A. Moschel, Sarah J. Schuchardt
  • Publication number: 20240058130
    Abstract: An implantable penile prosthesis system has a penile implant with a proximal portion provided with an annular groove and a neck groove, and a rear tip extender forming a cavity sized to receive the proximal portion of the penile implant. The cavity of the rear tip extender is provided with a plurality of locks. The locks include a distal lock formed as an annular protrusion sized to engage with the annular groove of the penile implant and a proximal lock formed as a wedge-shaped tooth sized to engage the neck groove of the penile implant.
    Type: Application
    Filed: August 10, 2023
    Publication date: February 22, 2024
    Inventors: John J. Allen, Linda Cornelius
  • Publication number: 20240033087
    Abstract: A penile prosthesis includes a first penile implant implantable into a first corpora cavernosum and a second penile implant implantable into a second corpora cavernosum, and a pump assembly coupled to the implants by tubing. Each implant includes a tubular film sealed in a liquid-tight arrangement between a proximal tip implantable into a crus penis and a distal tip implantable into a glans penis, a scaffold nested inside of the tubular film, and a first liquid volume contained inside of the tubular film.
    Type: Application
    Filed: October 13, 2023
    Publication date: February 1, 2024
    Inventors: Frederick William Hamlin, John J. Allen, Rahul Dilip Sathe, Neal Poucher
  • Patent number: 11849935
    Abstract: A tissue anchor assembly comprises a tissue anchor; a suture; and an adjustment button coupled with the suture. The adjustment button is adapted to adjust tension relative in the suture. When tension is applied to a second suture section trailing away from the tissue anchor, the adjustment button is engaged with the second suture section through locking splines and the adjustment button slides along a portion of the suture to increase a distance between the adjustment button and the tissue anchor. When tension is applied to a first suture section trailing away from the tissue anchor, the adjustment button moves in a direction towards the tissue anchor to reduce a distance between the adjustment button and the tissue anchor.
    Type: Grant
    Filed: May 26, 2021
    Date of Patent: December 26, 2023
    Assignee: Coloplast A/S
    Inventor: John J. Allen
  • Patent number: 11819412
    Abstract: A penile prosthesis has an energy assembly coupled to a proximal end of a tubular body. The energy assembly has a housing enclosing a piston, a heating element, and a liquid phase change material (PCM) sealed between an interior surface of the housing and the piston. When the heating element heats the liquid PCM to a gaseous state, the piston moves in a distal direction to increase pressure in the tubular body and provide the prosthesis with erection.
    Type: Grant
    Filed: February 3, 2021
    Date of Patent: November 21, 2023
    Assignee: Coloplast A/S
    Inventors: Frederick William Hamlin, John J. Allen, Rahul Dilip Sathe, Neal Poucher, Kellie J. Giese
  • Publication number: 20230118607
    Abstract: A Y-shaped support has a head section having a first free end and a second end secured to a leg section, with the leg section having a first leg extending from the second end of the head section and a second leg extending from the second end of the head section. A first connector is provided as a first interlocking stitch, with the first interlocking stitch passed through open leg spaces of the first leg and open head spaces in the head section. A second connector is provided as a second interlocking stitch, with the second interlocking stitch passed through the aligned open leg spaces of the first leg and the second leg to connect the first leg to the second leg. The second end of the head section is located outside a space where the first leg is connected to the second leg.
    Type: Application
    Filed: November 2, 2022
    Publication date: April 20, 2023
    Inventors: Sarah J. Schuchardt, Michael M. Witzmann, John J. Allen, David Richmond, Matthew George Litton
  • Publication number: 20230047736
    Abstract: An inflatable bladder of a penile prosthesis has a multi-layered wall structure with a wall spacing between walls to allow an interior distal wall end to move independently of an exterior distal wall end.
    Type: Application
    Filed: August 11, 2022
    Publication date: February 16, 2023
    Inventors: John J. Allen, Megan Lenz
  • Patent number: D980424
    Type: Grant
    Filed: April 29, 2020
    Date of Patent: March 7, 2023
    Assignee: Coloplast A/S
    Inventors: John J. Allen, John Clegg, Mark A. Moschel, Sarah J. Schuchardt
  • Patent number: D1030055
    Type: Grant
    Filed: January 26, 2023
    Date of Patent: June 4, 2024
    Assignee: Coloplast A/S
    Inventors: John Clegg, John J. Allen, Peter Meinz, William Hartsig, Mark A. Moschel