Abstract: Various aspects of the present invention provide compositions and implantable devices including a water-insoluble therapeutic agent solubilized in a matrix of a gallate-containing compound. Other aspects provide methods of manufacturing and using such compositions and devices.

Abstract: A railcar lever system for decoupling a first railcar from a second railcar, the system includes a first elongated lever having a working element to engage with a lock lifter at a first end and a stop at an opposing second end; a second elongated lever having a handle at a first end and a stop at an opposing second end; a middle elongated lever configured to slidingly engage with both the first elongated lever and the second elongated lever; a first bracket rigidly secured to a first surface of the middle elongated lever, the first bracket being configured to slidingly receive the first elongated lever; a second bracket rigidly secured to a second surface of the middle elongated, the second bracket being configured to slidingly receive the second elongated lever; a first guide pad removeably attached to the first bracket, the first guide being disposed between an inner surface of the first bracket and an outer surface of the first elongated lever; and a second guide pad removeably attached to the second brack

Abstract: An impact nozzle that atomizes fuel and minimizes liquefication at a supercharger intake manifold comprises a body defining an enclosed channel having proximal and distal ends, a means for attaching a jet to the proximal end, and a pedestal spanning the distal end. An impact pin extending proximally from the pedestal is spaced distally from the distal end of the channel. The impact pin may be mounted to a central longitudinal member having four contoured sides each having a maximum thickness at its distal end and a minimum thickness at its proximal end, the minimum thickness occurring along one of four straight edges that define a rectangular end of the central longitudinal member to which the impact pin is attached, and each border between any two contoured sides forming a sharp contoured edge for evenly dispersing atomized fuel.

Abstract: The invention relates to a pipe arrangement (10) with a fluid-carrying inner pipe (12) and an outer pipe (14) that surrounds the inner pipe (12), wherein spacers (20, 24) are arranged between the inner pipe (12) and the outer pipe (14) in such a way that a gap (16) is formed between the inner pipe (12) and the outer pipe (14), wherein the outer pipe (14) is joined at its first axial end section (18) in a material-bonded or cohesive manner to a first spacer (20), which is joined to the inner pipe (12) in a material-bonded manner, and wherein the outer pipe (14) is arranged at its second axial end section (22) at least partially with a radial spacing (26) to a second spacer (24), which is joined to the inner pipe (12) in a material-bonded manner.

Abstract: Circuits, devices and methods are disclosed, including radio-frequency circuitry comprising a polar modulator configured to invert a sampled transmitted signal into an inverted sampled transmitted signal, a signal combiner configured to combine the inverted sampled transmitted signal with a received signal and a control logic circuit coupled to the polar modulator, the control logic circuit configured to adjust one or more tuning parameters of the polar modulator for inverting the sampled transmitted signal.

Abstract: A system and method for an image reconstruction user interface is provided. An imaging system may be used to scan a subject and provide reconstructed images of the subject. Reconstructed images may be output to a display, printer, network, and/or memory storage device. To view information and select options for image reconstruction, a visualization system and method is utilized.

Abstract: A radio-frequency (RF) module includes a first transistor having a base, a collector, and an emitter, a radio-frequency output transmit path coupled to the collector of the first transistor at a first end and to a radio-frequency output port at a second end, and an output matching network disposed in the radio-frequency output transmit path, the output matching network including a shunt arm coupled to ground, the shunt arm including a switch that is controllable to modify an impedance of the output matching network.

Abstract: A sampling system is provided. The sampling system includes a housing. Mounted to the housing is a Hall effect sensor. A probe configured to contact a sample is inserted into the housing. The probe includes an elongated portion and a restorative spring inserted onto the elongated portion of the probe. The restorative spring provides sufficient restorative force to return the probe to a relaxed position. The Hall effect sensor is configured to sense a field strength generated by the proximity of the restorative spring of the probe in the extended position.

Abstract: Various aspects of the present invention provide compositions and implantable devices including a water-insoluble therapeutic agent solubilized in a matrix of a gallate-containing compound.

Abstract: The invention relates to methods of using an effective amount of activated protein C (APC) to treat an individual for a skin disorder characterised by the presence of hyperproliferative keratinocytes.

Abstract: A compact integrated optical system including an eyepiece, a reflective telescope, and a multi-spectral combiner optically coupled between the reflective telescope and the eyepiece, and configured to direct visible light received via the reflective telescope assembly along a direct view optical path to the eyepiece assembly. In one example, the multi-spectral combiner includes a display that displays a visual representation of the imagery of the viewed scene, and laser range-finder transceiver that transmits and receives a laser beam via the reflective telescope. A pair of beamsplitters is used to separate the imaging optical path from the direct view and laser range-finding optical paths. A blocking device is used to enable laser range-finding capability during daytime viewing of the imaging optical path imagery on the display. The reflective telescope provides a common aperture for the direct view optical path, an imaging optical path, and the laser range-finder transceiver.

Abstract: A method of separating heavy water from normal through application of acoustic pressure shock waves to a fluid including heavy water and normal water and recovering separated normal water.

Abstract: Acoustic pressure shock waves are applied to a membrane in a fluid to prevent attachment of or dislodge biological or solid matter for membrane cleaning or desalination with a membrane.

Abstract: A method of desalinating water through application of acoustic pressure shock waves to a slush to separate ice crystals from brine and recovering desalinated water from the separated ice crystals.

Abstract: Various aspects of the present invention provide compositions and implantable devices including a water-insoluble therapeutic agent solubilized in a matrix of a gallate-containing compound.

Abstract: The invention relates to the prevention and treatment of pathologic scars using APC or analogue thereof.

Abstract: A system and method for an image reconstruction user interface is provided. An imaging system may be used to scan a subject and provide reconstructed images of the subject. Reconstructed images may be output to a display, printer, network, and/or memory storage device. To view information and select options for image reconstruction, a visualization system and method is utilized.

Abstract: Medical devices utilizing shock waves with spark gap electrodes that include fluid holes into the respective electrode cores.

Abstract: The present application relates to wound repair and wound healing by the application of a therapeutic amount of Activated Protein C-3K3A (‘APC-3K3A’). Specifically, this application is directed to a method of using APC-3K3A for the treatment of dermal or cutaneous wounds, including but not limited to, acute and chronic wounds, burns and ulcers.