Abstract: An article of footwear with an upper having a knitted component in an instep region extending between a first side and a second side. Outer lace apertures and inner lace apertures are disposed along the instep area on the first side and, in some aspects, the second side, where inner lace apertures are located more inward towards a middle of the upper than outer lace apertures. A lace extends through an inner lace aperture from an exterior surface on the first side of the upper, along an interior surface of the upper, and then exits the upper through an outer lace aperture on the first side. After exiting the outer lace aperture on the first side, the lace extends across the instep area along the exterior surface of the upper and extends through a lace aperture on the second side, which may be an inner lace aperture.

Abstract: A system for sterilizing or bioburden-reducing a filter device includes a breathable microbial barrier, a filter device, and a tubing arrangement. The tubing arrangement may be coupled to at least one opening of the filter device. The tubing arrangement may include an aseptic connector, a sealable component, and a port, all of which are in fluid communication with one another. The sealable component may be disposed in the tubing arrangement between the at least one opening of the filter device and the aseptic connector. The sealable component may be reconfigurable between an open configuration, which facilitates the entry of a sterilization vapor into the tubing arrangement and the filter device when subjected to a sterilization or bioburden reduction process, and a closed configuration, where the tubing arrangement is sealed from a surrounding environment. The breathable microbial barrier may at least partially enclose the port of the tubing arrangement.

Abstract: In one aspect, a method is provided herein of preparing a drug delivery device, the drug delivery device having a body with at least one fluid duct being open along a first face of the body, the at least one fluid duct for conveying drug from at least one reservoir to a needle configured for injection into a patient, the method including: providing a barrier across the first face of the body to at least cover the at least one fluid duct, wherein the barrier is ultraviolet transmissive; and, exposing the first face of the body to ultraviolet radiation so as to allow the ultraviolet radiation to pass through the barrier and decontaminate the at least one fluid duct.

Abstract: A negative pressure wound therapy system can include a source of negative pressure negative pressure configured to aspirate fluid from a wound covered by a wound dressing and electronic circuitry with a power source, boost converter circuitry configured to receive power at a first level from the power source and supply power at a second level to the source of negative pressure, the second level being higher than the first level, and a controller configured to, in response to a determination that a capacity of the power source is being depleted, cause the boost converter circuitry to supply power to the source of negative pressure at a third level lower than the second level. The controller can further lower a target negative pressure level associated with negative pressure provided by the source of negative pressure.

Abstract: A memory module comprises an address buffer circuit, a command/address channel, and a plurality of memory components controlled by the address buffer circuit via the command/address channel. At least one memory component comprises a plurality of data ports, a memory core to store data, and a data interface. The data interface is capable of transferring data between the memory core and the data ports. The data interface supports a first data width mode in which the data interface transfers data at a first bit width and a first burst length via the data ports. The data interface also supports a second data width mode in which the data interface transfers data at a second bit width and second burst length via the data ports. The first bit width is greater than the second bit width and the first burst length is shorter than the second burst length.

Abstract: A method for forming and installing a retaining ring comprises: feeding a wire in a linear path into a forming die having a circular bore; forming, using the forming die, the wire into a formed ring having a ring shape; transferring the formed ring from the forming die to a transfer puck; and installing the formed ring, as a retaining ring, in a tube of a product assembly. The formed ring is maintained in a constrained state between forming in the forming die and installation in the product assembly. A system for forming and installing a retaining ring into a product assembly includes a forming die configured to form a wire into a formed ring having a ring shape; and a transfer puck to transfer the formed ring from the forming die. The formed ring is maintained in a constrained state from forming through installation.

Abstract: A storage system performs garbage collection, with data compression, in storage memory. The system obtains hash results from data segments. The system determines similarity of content of data segments, based on the hash results. The system performs data compression of live data of two or more data segments that have similarity of content meeting a similarity threshold. The system writes the compressed live data of the two or more data segments into the storage memory.

Abstract: The present disclosure provides for chimeric antigen receptors (CARs) that specifically target a G-protein coupled receptor, G-protein coupled receptor family C group 5 member D (GPRC5D), and immunoresponsive cells comprising such CARs, for the treatment of cancer.

Abstract: The present invention describes a method using temperature data to protect battery health during bidirectional charging in conjunction with monetization activities. The method includes receiving temperature data and determining anticipated energy needs of a building. The temperature data includes at least the temperature of one or more electric vehicle batteries or information required to determine the temperature of the one or more electric vehicle batteries while the anticipated energy needs are relative to ambient air temperature. The method includes determining an amount of discharge of the one or more electric vehicle batteries required to offset the anticipated needs of the building by a predetermined amount and determining based on the temperature data whether discharging the one or more electric vehicle batteries would be harmful to the health of the one or more electric vehicle batteries.

Abstract: This document relates to methods and materials for treating a mammal having an autoimmune disease. For example, materials and methods for producing an immuno-activatable cell comprising a first chimeric antigen receptor and a second chimeric antigen receptor are provided. Methods and materials for treating a mammal having an autoimmune disease comprising administering an immuno-activatable cell are also provided.

Abstract: Some embodiments of the invention provide a forwarding element (e.g., a switch, a router, etc.) that has one or more data plane, message-processing pipelines with key-value processing circuits. The forwarding element's data plane key-value circuits allow the forwarding element to perform key-value services that would otherwise have to be performed by data compute nodes connected by the network fabric that includes the forwarding element. In some embodiments, the key-value (KV) services of the forwarding element and other similar forwarding elements supplement the key-value services of a distributed set of key-value servers by caching a subset of the most commonly used key-value pairs in the forwarding elements that connect the set of key-value servers with their client applications.

Abstract: This invention pertains to improved polyester polyol compositions comprising 2,2,4,4-tetramethyl-1,3-cyclobutanediol (TMCD). Coating compositions based on such TMCD polyester polyols are capable of providing a good balance of the desirable coating properties, such as solvent resistance, acid resistance, retort resistance, microcracking resistance, and bending ability, for metal packaging applications.

Abstract: Antenna assemblies are described herein. In particular, described herein are multi-focal-point antenna devices and compact radio frequency (RF) antenna devices. Any of these assemblies may include a primary feed that includes a single patterned emitting surface from which multiple different beams of RF signals are emitted corresponding to different antenna input feeds each communicating with the patterned antenna emitting surface. The antenna assembly is therefore capable of emitting beams in the same direction having different polarizations using a single primary feed.

Abstract: A system may include a flow sensor and a base. The flow sensor may include a flow tube, a sensor configured to characterize at least one attribute of a fluid in the flow tube, and an electrical contact in electrical communication with the sensor. The flow tube may include a fluid inlet at a first end of the flow tube, a fluid outlet at a second end of the flow tube, a fluid injection port between the first and second ends of the flow tube, and a valve configured to control a flow of a fluid in the flow tube. The base may include a processor, an electrical contact in electrical communication with the processor, a short range wireless communication device, and a display. The flow sensor electrical contact may be in electrical communication with the base electrical contact when the flow sensor is connected to the base.

Abstract: An absorbent article in the form of a feminine hygiene pad is disclosed. The article includes a topsheet formed of a section of formed nonwoven web material having an ordered arrangement of zones, each zone comprising one or more attenuated regions adjacent to one or more built-up regions, wherein the attenuated regions have a first average basis weight and the built-up regions have a second average basis weight. Through configuration of the regions and the ordered arrangement, inclusion of melt additive to the resin(s) from which the filaments are spun and/or application of a surfactant to a surface of the topsheet, the topsheet may be imparted with a Rewet of no greater than 0.50 g and an Acquisition Time of no greater than 25 seconds, balancing competing topsheet performance characteristics in a manner acceptable or preferable for consumers/users.

Abstract: A method of fabricating thermal and/or acoustical insulation products including glass fibers and formaldehyde-free, substantially water-insoluble, thermoset resin binders, which binders afford thermal and/or acoustical insulation products requiring less cutting force during fabrication and promote greater wearability, durability, and/or longevity for cutting blades used in fabrication.

Abstract: Devices and/or methods for treating sleep disordered breathing may include stimulation of a single nerve, multiple nerves, as well as other tissues relating to upper airway patency.

Abstract: Provided herein are specific inhibitors, compositions, methods and uses for reducing expression of COASY in a cell or individual. Such specific inhibitors, compositions, and methods are useful to treat a liver disease or disorder, including but not limited to NASH, in a subject.