Patents by Inventor John Lowe

John Lowe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF
    Publication number: 20150376195
    Abstract: Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related disorders. Orally available formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed.
    Type: Application
    Filed: January 29, 2014
    Publication date: December 31, 2015
    Inventors: John A. Lowe, III, M. Amin Khan
  • SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF
    Publication number: 20150368253
    Abstract: Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related disorders. Orally available formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed.
    Type: Application
    Filed: January 29, 2014
    Publication date: December 24, 2015
    Inventors: John A. Lowe, III, M. Amin Khan
  • SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF
    Publication number: 20150368252
    Abstract: Disclosed are compounds having enhanced potency in the modulation of NMD A receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related disorders. Orally available formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed.
    Type: Application
    Filed: January 29, 2014
    Publication date: December 24, 2015
    Applicant: NAUREX, INC.
    Inventors: John A. Lowe, III, M. Amin Khan
  • SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF
    Publication number: 20150368254
    Abstract: Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related disorders. Orally available formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed.
    Type: Application
    Filed: January 29, 2014
    Publication date: December 24, 2015
    Inventors: John A. Lowe, III, M. Amin Khan
  • Reinforcement Strip for Use in Airbags and Methods of Their Manufacture
    Publication number: 20150321637
    Abstract: A vehicle safety device, along with its methods of formation and use, is provided. The vehicle safety device comprises: an airbag; a pyrotechnic device positioned within working proximity to an aperture defined in the airbag and configured to fill the interior space of the airbag with a gas upon ignition; and a reinforcement strip positioned within the interior of the airbag on a seam joining a first fabric section and a second fabric section of the airbag. The reinforcement strip comprises a point-bonded sheet, such as a point-bonded nonwoven web of thermoplastic and/or thermoset polymers.
    Type: Application
    Filed: March 16, 2015
    Publication date: November 12, 2015
    Inventor: Vernon John Lowe
  • Pyridazine derivatives, compositions and methods for treating cognitive impairment
    Patent number: 9145372
    Abstract: This invention relates to pyridazine derivatives, compositions comprising therapeutically effective amounts of those pyridazine derivatives and methods of using those derivatives or compositions in treating central nervous system (CNS) disorders with cognitive impairment that are responsive to agonists of ?5 subunit containing GABAA receptor, e.g., age-related cognitive impairment, Mild Cognitive Impairment (MCI), dementia, Alzheimer's Disease (AD), prodromal AD, post traumatic stress disorder (PTSD), schizophrenia and cancer-therapy-related cognitive impairment.
    Type: Grant
    Filed: November 15, 2011
    Date of Patent: September 29, 2015
    Assignee: AGENEBIO, INC.
    Inventor: John A. Lowe, III
  • Heat Resistant Coating for Use in Airbags and Methods of Their Manufacture
    Publication number: 20150266264
    Abstract: A heat shield is generally provided, along with methods of making the heat shield and its use in a vehicle safety device (e.g., an airbag). In one embodiment, the heat shield includes a base substrate (e.g., a nonwoven fabric, a woven fabric, or a film); a heat resistant coating on the base substrate; and a first point-bonded sheet laminated to the heat resistant coating such that the first point-bonded sheet forms an outer surface of the heat shield with the heat resistant coating positioned between the first point-bonded sheet and the base substrate. The heat resistant coating generally comprises particles of an inorganic mineral (e.g., vermiculite, mica, or a combination thereof) dispersed within a film-forming binder (e.g., an acrylic resin, a styrene-butadiene rubber, a polyvinyl alcohol, an ethyl vinyl acetate resin, a phenolic resin, or a combination thereof).
    Type: Application
    Filed: August 27, 2013
    Publication date: September 24, 2015
    Inventors: Vernon John Lowe, Steven F. Nielsen
  • Idiotypic antibodies and uses thereof
    Patent number: 9139659
    Abstract: The invention provides anti-idiotypic HCMV antibodies as well as methods of using the same.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: September 22, 2015
    Assignee: GENENTECH, INC.
    Inventors: Jo-Anne Hongo, Yanhong Li, Luna Liu, John Lowe, Mauricio Maia, Rajesh Vij, Terence Wong, Keyang Xu
  • Prodrugs of Secondary Amine Compounds
    Publication number: 20150210712
    Abstract: The present invention relates to compounds of Formula I:
    Type: Application
    Filed: February 3, 2015
    Publication date: July 30, 2015
    Inventors: Laura Cook Blumberg, John A. Lowe, III, Orn Almarsson, Juan Alvarez, Tarek A. Zeidan
  • SYSTEM FOR CONTROLLING PRODUCTION OF FOOD PRODUCTS
    Publication number: 20150187027
    Abstract: A method of controlling ordering and production of food products in a restaurant, constructing a composite queue from time slots associated with customers standing physical lines to place their orders at manual registers, and time slots associated with customers placing their orders electronically over a communications network, determining, in regard to a current order load states of at least some cooking areas in a kitchen, determining whether one of the load states varies from a pre-determined load state by a first threshold amount, and if so determining an increment to the service delay for the current order, and communicating information about the increment to the customer being served.
    Type: Application
    Filed: June 26, 2013
    Publication date: July 2, 2015
    Inventor: Ian John Lowe
  • Prodrugs of secondary amine compounds
    Patent number: 8969337
    Abstract: The present invention relates to compounds of Formula I:
    Type: Grant
    Filed: December 14, 2012
    Date of Patent: March 3, 2015
    Assignee: Alkermes Pharma Ireland Limited
    Inventors: Laura Cook Blumberg, John A. Lowe, Orn Almarsson, Juan Alvarez, Tarek A. Zeidan
  • Cartridge EGR valve assembly
    Patent number: 8939174
    Abstract: A drop-in cartridge style, four-chamber EGR valve, includes a valve actuator, a valve stem extending from the valve actuator and having two valve heads mutually spaced on the stem, and a frame having a plurality of longitudinally extending members connected by at least first and second ring members, the frame being divided along a longitudinal axis into two mating parts.
    Type: Grant
    Filed: December 20, 2010
    Date of Patent: January 27, 2015
    Assignee: Mack Trucks, Inc.
    Inventors: John Sponsky, John Lowe
  • Hinged rocker arm and valve opening arrangement including a hinged rocker arm
    Patent number: 8904982
    Abstract: A hinged rocker arm includes a first wing including a first opening for receiving a rocker shall and a first contacting surface, and a second wing including a second opening for receiving the rocker shaft, the second wing including a second contacting surface When the first and second wings are mounted on the rocker shaft, the first contacting surface and the second contacting surface are adapted to contact each other and thereby transfer a force in a direction transverse to an axis of the rocker shaft.
    Type: Grant
    Filed: November 17, 2010
    Date of Patent: December 9, 2014
    Assignee: Mack Trucks, Inc.
    Inventor: John Lowe
  • System, Methods, and Apparatus for Interactive Advertising
    Publication number: 20140337178
    Abstract: The present invention relates to a system and methodology for searching and presenting merchant and advertised information to a user over a wide area network such as the Internet. The system and method actively links manufacturer and merchant information within a search query so as to enable a user to conduct more efficient searching when seeking products or services in a proximity or geographical area. This Abstract is provided for the sole purpose of complying with the Abstract requirement rules that allow a reader to quickly ascertain the subject matter of the disclosure contained herein. This Abstract is submitted with the explicit understanding that it will not be used to interpret or to limit the scope or the meaning of the claims.
    Type: Application
    Filed: May 13, 2014
    Publication date: November 13, 2014
    Inventor: John Lowe
  • MODULAR FILTER CASSETTE
    Publication number: 20140246383
    Abstract: The present disclosure relates to modular filtration cassettes for filtering liquids including, for example, liquids used in semiconductor manufacturing. A filter housing may define a filter cavity comprising an upstream portion and a downstream portion. The filter may further comprise a filter element disposed in the filter cavity. The filter element may at least partially overlap the filter inlet on a first side of the filter element. The filter element may comprise a rectangular pleated filter with a set of pleats having a first set of pleat tips on an upstream side of the filter element and a second set of pleat tips on a downstream side of the pleated filter.
    Type: Application
    Filed: October 3, 2012
    Publication date: September 4, 2014
    Applicant: Entegris, Inc.
    Inventors: John P. Puglia, Louis Barrows, Christopher John Lowe, Ben Mai Pak Lee, Marc Laverdiere
  • MODULAR FILTRATION SYSTEM
    Publication number: 20140238922
    Abstract: The present disclosure relates to modular filtration systems using removable filter cassettes for filtering liquids including, for example, liquids used in semiconductor manufacturing. A filtration system may include a removable filter cassette having a filter inlet port and a filter outlet port, a filter cassette holder configured to receive and retain the filter cassette, and a main assembly. The main assembly can further comprise a filter inlet interface port configured to receive the filter inlet port, and a filter outlet interface port configured to receive the filter outlet port and can define flow paths to direct flow to and from the filter cassette. The filter cassette holder may be movably coupled to the main assembly such that the filter cassette is movable relative to the main assembly from an unmated position to a mated position.
    Type: Application
    Filed: October 3, 2012
    Publication date: August 28, 2014
    Applicant: Entegris, Inc.
    Inventors: John P. Puglia, Louis Barrows, Christopher John Lowe, Ben Mai Pak Lee, Marc Laverdiere
  • LRRK2 INHIBITORS
    Publication number: 20140205537
    Abstract: Provided herein are compounds that inhibit or partially inhibit the activity of leucine rich repeat kinases. Also provided herein are methods of treatment of CNS disorders comprising administration of inhibitors of leucine rich repeat kinases.
    Type: Application
    Filed: June 22, 2012
    Publication date: July 24, 2014
    Applicant: ZENOBIA THERAPEUTICS, INC.
    Inventors: Pierre-Yves Bounaud, Vicki Nienaber, Ruo W. Steensma, John A. Lowe, III
  • System, methods, and apparatus for interactive advertising
    Patent number: 8732016
    Abstract: The present invention relates to a system and methodology for searching and presenting merchant and advertised information to a user over a wide area network such as the Internet. The system and method actively links manufacturer and merchant information within a search query so as to enable a user to conduct more efficient searching when seeking products or services in a proximity or geographical area. This Abstract is provided for the sole purpose of complying with the Abstract requirement rules that allow a reader to quickly ascertain the subject matter of the disclosure contained herein. This Abstract is submitted with the explicit understanding that it will not be used to interpret or to limit the scope or the meaning of the claims.
    Type: Grant
    Filed: September 18, 2007
    Date of Patent: May 20, 2014
    Assignee: Poynt Inc.
    Inventor: John Lowe
  • Optical processing
    Patent number: 8610839
    Abstract: An optical processing system is described that allows rapid evaluation of derivatives and partial derivatives by means of optical Fourier transformation. In embodiments, separate filtering steps are used to provide phase and amplitude changes.
    Type: Grant
    Filed: March 10, 2008
    Date of Patent: December 17, 2013
    Assignee: Optalysis Ltd.
    Inventors: Nicholas James New, Andrew John Lowe, Timothy David Wilkinson, John Robert Brocklehurst
  • IDIOTYPIC ANTIBODIES AND USES THEREOF
    Publication number: 20130266973
    Abstract: The invention provides anti-idiotypic HCMV antibodies as well as methods of using the same.
    Type: Application
    Filed: March 15, 2013
    Publication date: October 10, 2013
    Inventors: Jo-Anne Hongo, Yanhong Li, Luna Liu, John Lowe, Mauricio Maia, Rajesh Vij, Terence Wong, Keyang XU