Patents by Inventor John M. Antos

John M. Antos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8940501
    Abstract: The present invention relates to methods for ligation. The invention provides novel reagents and methods for ligating an acyl donor compound with an acyl acceptor compound. Provided acyl donor compounds comprise a transamidase recognition sequence that allows ligation with a nucleophilic acyl acceptor in the presence of transamidase. The invention further provides kits comprising acyl donor compounds and optionally comprising other reagents for ligation.
    Type: Grant
    Filed: February 1, 2010
    Date of Patent: January 27, 2015
    Assignee: Whitehead Institute for Biomedical Research
    Inventors: Hidde L. Ploegh, John M. Antos, Maximilian Wei-Lin Popp, Carla Guimaraes
  • Publication number: 20110321183
    Abstract: The present invention relates to methods for ligation. The invention provides novel reagents and methods for ligating an acyl donor compound with an acyl acceptor compound. Provided acyl donor compounds comprise a transamidase recognition sequence that allows ligation with a nucleophilic acyl acceptor in the presence of transamidase. The invention further provides kits comprising acyl donor compounds and optionally comprising other reagents for ligation.
    Type: Application
    Filed: February 1, 2010
    Publication date: December 29, 2011
    Applicant: Whitehead Institute for Biomedical Research
    Inventors: Hidde L. Ploegh, John M. Antos, Maximilian Popp Wei-Lin, Carla Guimaraes
  • Patent number: 7753461
    Abstract: A refrigerator shelving system includes an item retainer for securing items carried on a shelf, a mounting member for releasably securing a shelf to a cabinet of the refrigerator, and a spill tray carried by the shelf. The item retainer is movable between a first position and a second position such that when in the first position, a first side upwardly extends from the shelf and defines a fence and when in the second position the first side is parallel and adjacent to an upper surface of the shelf. The shelf mounting member includes a first portion rotatably interconnected to a lateral side of the shelf and a second portion for selectively engaging a horizontal slot of a cabinet of the refrigerator. The mounting member is rotatable from a first position to a second position to engage the second portion with the horizontal slot. The spill tray includes a main body portion and a plurality of mounting elements.
    Type: Grant
    Filed: October 21, 2002
    Date of Patent: July 13, 2010
    Assignee: Thetford Corporation
    Inventors: David W. Leistner, John M. Antos, James C. Butler, John W. Wissinger
  • Patent number: 7350886
    Abstract: A refrigerator storage bin includes a main body portion and a cover. The main body portion defines a bin storage area. The cover selectively provides access to the bin storage area. The cover is pivotally attached to a sidewalk of a cabinet of the refrigerator for rotation about a pivot axis between an opened position and a closed position. The cover and main body portion include cooperating surfaces that articulate to cover from the closed position to the open position in response to translation of the main body portion from a first position to a second position.
    Type: Grant
    Filed: October 21, 2002
    Date of Patent: April 1, 2008
    Assignee: Thetford Corporation
    Inventors: John M. Antos, Wilco Wessels
  • Patent number: 7097213
    Abstract: A latching arrangement for a refrigerator door includes a striker unit, a first latch arm and a second latch arm. The striker unit is secured to a cabinet of the refrigerator. The first latch arm is interconnected to the door for pivotal movement about a generally horizontal axis between a latched position and an unlatched position. In the latched position, the first arm releasably engages a first striker portion of the striker unit. The second latch arm is interconnected to the door for pivotal movement about a generally vertical axis between a latched position and an unlatched position. In the latched position, the second latch arm releasably engages a second striker portion of the striker unit.
    Type: Grant
    Filed: October 21, 2002
    Date of Patent: August 29, 2006
    Assignee: Thetford Corporation
    Inventors: John M Antos, James C Butler
  • Patent number: 6827410
    Abstract: A door assembly for a refrigerator having a cabinet with a cabinet opening, a cabinet height and a cabinet width includes a main body portion and a cap portion. The main body portion has a door height and a door width generally corresponding in size to the cabinet height and the cabinet width, respectively. The cap portion is secured to and upwardly extends from the main body portion. The cap is configured to substantially cover a plurality of control elements upwardly extending from the cabinet when the door assembly is articulated to a closed position.
    Type: Grant
    Filed: August 22, 2002
    Date of Patent: December 7, 2004
    Assignee: Thetford Corporation
    Inventors: John M. Antos, James C. Butler
  • Publication number: 20040189015
    Abstract: A latching arrangement for a refrigerator door includes a striker unit, a first latch arm and a second latch arm. The striker unit is secured to a cabinet of the refrigerator. The first latch arm is interconnected to the door for pivotal movement about a generally horizontal axis between a latched position and an unlatched position. In the latched position, the first arm releasably engages a first striker portion of the striker unit. The second latch arm is interconnected to the door for pivotal movement about a generally vertical axis between a latched position and an unlatched position. In the latched position, the second latch arm releasably engages a second striker portion of the striker unit.
    Type: Application
    Filed: April 22, 2004
    Publication date: September 30, 2004
    Inventors: John M Antos, James c Butler
  • Publication number: 20030038139
    Abstract: A door assembly for a refrigerator having a cabinet with a cabinet opening, a cabinet height and a cabinet width includes a main body portion and a cap portion. The main body portion has a door height and a door width generally corresponding in size to the cabinet height and the cabinet width, respectively. The cap portion is secured to and upwardly extends from the main body portion. The cap is configured to substantially cover a plurality of control elements upwardly extending from the cabinet when the door assembly is articulated to a closed position.
    Type: Application
    Filed: August 22, 2002
    Publication date: February 27, 2003
    Inventors: John M. Antos, James C. Butler
  • Patent number: 6158061
    Abstract: A sanitary toilet system with an integral water supply and manual flush assembly for a recreational vehicle in which a flush water supply tank is provided adjacent a recreational vehicle wall with an inlet extending through the wall, thus eliminating plumbing within the vehicle between a water inlet and the supply tank. A manually operated piston pump is provided in which a clearance exists between the piston and the pump cylinder allowing water to flow past the piston during operation of the pump. This reduces the forces necessary to operate the pump in comparison to a piston in sealing relation to the cylinder.
    Type: Grant
    Filed: January 16, 1996
    Date of Patent: December 12, 2000
    Assignee: Thetford Corporation
    Inventors: David B. Cameron, John M. Antos, Charles L. Sargent
  • Patent number: 6000771
    Abstract: A refrigerator for RVs comprising an upright cabinet with an internal cold compartment and a door member mounted on the cabinet for closing said compartment, two pairs of upright hinge pins on the cabinet on opposite sides of the door enables the door to swing from both right and left sides of the cabinet. A single actuator is provided for putting the door from a left swing to a right swing and vice versa. In addition, the actuator can secure the door on the cabinet during RV travel. It can also enable easy removal of the door from the cabinet. Cams and cam followers are associated with the cabinet and the door to cause the door to be lifted when opened and lowered when closed to assure easy opening and closing of the door.
    Type: Grant
    Filed: September 15, 1998
    Date of Patent: December 14, 1999
    Assignee: Thetford Corporation
    Inventors: John W. Wissinger, John R. Selina, James C. Butler, David W. Leistner, John M. Antos
  • Patent number: 5875499
    Abstract: The toilet with a deflector shield covering the flush nozzle to deflect a portion of the flush water. The deflected water flows downward to wet the bowl in the area beneath the flush water nozzle. The undeflected water flows onto a ledge at the upper end of the bowl and flows around the bowl where it gradually falls off the ledge and wets the remaining portion of the bowl. Both a foot pedal and a hand lever are provided for flushing the toilet and a cable is used to couple the foot pedal to the hand lever. The hand lever is operably connected to the flush water valve as well as the bowl discharge opening closure member to open both for flushing of the toilet.
    Type: Grant
    Filed: January 23, 1998
    Date of Patent: March 2, 1999
    Assignee: Thetford Corporation
    Inventors: John A. Hoffman, Kenneth J. Hall, John R. Selina, John M. Antos
  • Patent number: 5746466
    Abstract: A door assembly to be attached to a cutout in the side wall of a recreational vehicle for alternatively closing off and providing access to an internal compartment. A body frame is attached to the cut out in the side wall. A door panel is attached by a hinge to the body frame. A pair of push button latch mechanisms, one of which contains an integrated lock, retains the door panel in the closed position. The locking latch may be switched to the locked position when the door is open, automatically locking the door when it is closed. A flexible seal, incorporating a double sealing surface feature, is attached to the perimeter of the door and seats against the frame when the door is closed. The door panel includes a separate door wall and inner and outer door frames which are joined by a retaining clip. The metal retaining clip has a return bent upon itself shape and pointed wedge shaped upset portions for joining the outer and inner door frames.
    Type: Grant
    Filed: April 2, 1996
    Date of Patent: May 5, 1998
    Assignee: Thetford Corporation
    Inventors: John M. Antos, John R. Selina, David B. Cameron, James M. Byrne, Gerard Cornelis Rijn, Marinus Antonius Ros
  • Patent number: 5715544
    Abstract: A water flush toilet having an improved flush nozzle in which a portion of the flush water is discharged downward at a higher velocity from the nozzle over a rear section of a toilet bowl for scrubbing the rear section. The remainder of the water is discharged laterally outward at a lower velocity from the nozzle in opposite directions for flow in a spiral path over the bowl surface to rinse the bowl.
    Type: Grant
    Filed: November 22, 1995
    Date of Patent: February 10, 1998
    Assignee: Thetford Corporation
    Inventors: Carrie E. Huffman, John E. Hammond, George Grech, John M. Antos
  • Patent number: 5557810
    Abstract: A battery operated flush assembly for a portable toilet. The flush assembly includes a pump and motor mounted to the toilet's seat section. A battery pack is removably mounted to the seat section and includes terminals which, as a result of mounting, become coupled to the motor. The battery pack supplies electrical power to the motor and includes an actuator, protected from inadvertent actuation within a recess, for electrically closing the electrical circuit and causing operation of the pump to discharge flush water into the bowl. A check valve, located in-line with the discharged flush water, opens in response to the pumping of flush water and is maintained open with minimal line pressure to increase the life of the battery pack. An O-ring is also used to ensure that the battery pack can be easily removed and reinstalled with a fluid tight seal therearound.
    Type: Grant
    Filed: August 24, 1994
    Date of Patent: September 24, 1996
    Assignee: Thetford Corporation
    Inventors: John M. Antos, John R. Selina, James M. Byrne
  • Patent number: 5318275
    Abstract: A mechanism for multiplying rotation. The mechanism includes two armatures of differing lengths which rotate about different centers of rotation. The armatures are coupled together such that a rotation of one armature will produce a multiplied rotation in the other armature. The multiplying mechanism has particular application with a valve assembly of the type used in self-contained sanitary systems of recreational vehicles. The valve assembly includes a seal element having a sealing lip directed toward generally inward and downward of a fill opening a valve blade in the holding tank. The sealing lip terminates in a downwardly and outwardly oriented flange. The valve blade is actuatable through two movements. The first movement moves the valve blade generally vertically into and out of engagement with the seal element. The second movement moves the valve blade generally horizontally to a position out of registry with the fill opening.
    Type: Grant
    Filed: January 21, 1992
    Date of Patent: June 7, 1994
    Assignee: Thetford Corporation
    Inventors: Charles L. Sargent, John A. Hoffman, John M. Antos, Kevin B. Chlebek
  • Patent number: 5247974
    Abstract: A temporary sealing device for sealing a waste discharge conduit from an RV to an inlet receptacle of a waste receiving reservoir. The sealing device includes an inflatable bladder which is mounted so as to be positionable between the discharge conduit and the receptacle. A pump inflates the bladder to a size which seals the opening between the receptacle and the conduit to inhibit removal of the conduit and prevent the discharge of waste therearound. The sealing device is also provided with a valve which allows the bladder to be deflated after the transfer of waste and permits the conduit to be withdrawn from the receptacle.
    Type: Grant
    Filed: January 21, 1992
    Date of Patent: September 28, 1993
    Assignee: Thetford Corporation
    Inventors: Charles L. Sargent, John M. Antos, George Grech
  • Patent number: 5073994
    Abstract: A low water flush toilet having a bowl with a horizontal ledge extending around the bowl periphery near its open upper end with a flush water nozzle on the ledge for discharging water in a generally horizontal direction onto the ledge. A pulsator is provided for producing pulses of flush water that are discharged onto the ledge with the water of each pulse flowing at varying velocities such that as the water flows around the ledge, some of the water will fall off the ledge around substantially the entire periphery of the bowl resulting in wetting of the entire bowl surface for cleaning the bowl. The pulsator includes a spring biased piston for discharging pulses of water.
    Type: Grant
    Filed: September 12, 1990
    Date of Patent: December 24, 1991
    Assignee: Thetford Corporation
    Inventors: Charles L. Sargent, Michael A. Wolcott, John M. Antos
  • Patent number: 5060320
    Abstract: A toilet having a foot pedal flush control comprising two pedals, one for opening a toilet bowl discharge outlet and the other for supplying flush water to the bowl. The pedals both operate through actuation cables having a wire member slidable within a conduit. The flush water pedal can be independently actuated to partially fill the bowl prior to use of the toilet while the outlet closure member pedal coacts with the flush water pedal so that upon opening of the bowl outlet, the flush water pedal is depressed providing water to the bowl. The wire members are solid wire members coupled to the pedals for both pull and push operation so that upon a failure of the pedal return mechanism, the pedals can be manually returned closing the bowl outlet and terminating the flow of flush water to the bowl.
    Type: Grant
    Filed: June 25, 1990
    Date of Patent: October 29, 1991
    Assignee: Thetford Corporation
    Inventors: Charles L. Sargent, John M. Antos, David B. Cameron
  • Patent number: 5056166
    Abstract: A self-contained sanitary fixture, particularly for a recreational vehicle, comprises a bench supported on a base cooperatively defining a stowage compartment. The bench contains a bowl having an outlet which connects to a tank in the storage compartment. A valve on the tank controls passage between the bowl and the tank. The valve is itself operated from a knob on the bench through a coupling mechanism. Waste water from the bowl is collected in the tank and is disposed of by sliding the tank out of the stowage compartment through an opening in the RV's sidewall and carrying the tank to a suitable disposal site. The tank incorporates a rotatable pourspout and vent valve to facilitate pouring waste contents out of the tank. The connections between the bowl outlet and the tank and between the knob and valve automatically disconnect upon removal of the tank from the stowage compartment. Similarly they automatically reconnect when the tank is inserted back into the stowage compartment.
    Type: Grant
    Filed: July 2, 1990
    Date of Patent: October 15, 1991
    Assignee: Thetford Corporation
    Inventors: Charles L. Sargent, John M. Antos
  • Patent number: D390525
    Type: Grant
    Filed: April 2, 1996
    Date of Patent: February 10, 1998
    Assignee: Thetford Corporation
    Inventors: John M. Antos, John R. Selina, David B. Cameron, James M. Byrne, Gerard Cornelis Rijn, Marinus Antonius Ros