Patents by Inventor John M. Wozney

John M. Wozney has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bone and cartilage inductive proteins
    Patent number: 7378392
    Abstract: Purified cartilage and/or bone inductive proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and/or cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: October 6, 1994
    Date of Patent: May 27, 2008
    Assignee: Genetics Institute, LLC
    Inventors: Rodney M. Hewick, Jack H. Wang, John M. Wozney, Anthony J. Celeste
  • Tendon-inducing methods
    Patent number: 7365052
    Abstract: Compositions of proteins with tendon/ligament-like tissue inducing activity are disclosed. The compositions are useful in the treatment of tendinitis and tendon or ligament defects and in related tissue repair.
    Type: Grant
    Filed: June 17, 2005
    Date of Patent: April 29, 2008
    Assignees: Genetics Institute, LLC., President and Fellows of Harvard College
    Inventors: Anthony J. Celeste, John M. Wozney, Vicki A. Rosen, Neil M. Wolfman, Gerald H. Thomsen, Douglas A. Melton
  • BMP products
    Patent number: 7300772
    Abstract: Purified BMP-2 and BMP-4 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: March 9, 2001
    Date of Patent: November 27, 2007
    Assignee: Genetics Institute, LLC
    Inventors: Elizabeth A. Wang, John M. Wozney, Vicki A. Rosen
  • Methods of treatment of periodontal disease
    Patent number: 7217691
    Abstract: Purified BMP-2 and BMP-4 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: March 27, 2003
    Date of Patent: May 15, 2007
    Assignee: Genetics Institute, LLC
    Inventors: Elizabeth Wang, John M. Wozney, Vicki A. Rosen
  • BMP-11 compositions
    Patent number: 7175997
    Abstract: Purified BMP-11 proteins and processes for producing them are disclosed. Recombinant DNA molecules encoding the BMP-11 proteins are also disclosed. The proteins may be useful in regulating follicle stimulating hormone, such as for contraception. In addition, the proteins may be useful for the induction of bone, cartilage and/or other connective tissue.
    Type: Grant
    Filed: July 5, 2002
    Date of Patent: February 13, 2007
    Assignee: Genetics Institute, L.L.C.
    Inventors: John M. Wozney, Anthony J. Celeste
  • DNA molecules encoding BMP receptor proteins
    Patent number: 7091007
    Abstract: Novel serine/threonine receptor proteins and BMP receptor proteins are disclosed, as well as DNA molecules encoding the BMP receptor proteins and methods of using the receptor proteins. Further disclosed are truncated BMP receptor proteins and molecules which act as ligands to the BMP receptor proteins.
    Type: Grant
    Filed: June 23, 2003
    Date of Patent: August 15, 2006
    Assignee: Genetics Institute, LLC
    Inventors: John M. Wozney, Anthony J. Celeste, R. Scott Thies, Noboru Yamaji
  • Tendon-inducing compositions
    Patent number: 6984623
    Abstract: Compositions of proteins with tendon/ligament-like tissue inducing activity are disclosed. The compositions are useful in the treatment of tendinitis and tendon or ligament defects and in related tissue repair.
    Type: Grant
    Filed: February 18, 2004
    Date of Patent: January 10, 2006
    Assignees: Genetics, Institute Institute, LLC., President and Fellows of Harvard College
    Inventors: Anthony J. Celeste, John M. Wozney, Vicki A. Rosen, Neil M. Wolfman, Gerald H. Thomsen, Douglas A. Melton
  • Tendon-inducing compositions
    Publication number: 20040146923
    Abstract: Compositions of proteins with tendon/ligament-like tissue inducing activity are disclosed. The compositions are useful in the treatment of tendinitis and tendon or ligament defects and in related tissue repair.
    Type: Application
    Filed: February 18, 2004
    Publication date: July 29, 2004
    Applicants: Genetics Institute, LLC, President and Fellows of Harvard College
    Inventors: Anthony J. Celeste, John M. Wozney, Vicki A. Rosen, Neil M. Wolfman, Gerald H. Thomsen, Douglas A. Melton
  • Receptor proteins
    Publication number: 20040142417
    Abstract: Novel serine/threonine receptor proteins and BMP receptor proteins are disclosed, as well as DNA molecules encoding said proteins and methods of using the receptor proteins. Further disclosed are truncated BMP receptor proteins and molecules which act as ligands to said BMP receptor proteins.
    Type: Application
    Filed: June 23, 2003
    Publication date: July 22, 2004
    Applicant: Genetics Institute, LLC.
    Inventors: John M. Wozney, Anthony J. Celeste, R. Scott Thies, Noboru Yamaji
  • Tendon-inducing compositions
    Patent number: 6719968
    Abstract: Compositions of proteins with tendon/ligament-like tissue inducing activity are disclosed. The compositions are useful in the treatment of tendinitis and tendon or ligament defects and in related tissue repair.
    Type: Grant
    Filed: August 31, 2001
    Date of Patent: April 13, 2004
    Assignee: Genetics Institute, LLC.
    Inventors: Anthony J. Celeste, John M. Wozney, Vicki A. Rosen, Neil M. Wolfman, Gerald H. Thomsen, Douglas A. Melton
  • Methods of treatment of periodontal disease
    Publication number: 20040009916
    Abstract: Purified BMP-2 and BMP-4 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair.
    Type: Application
    Filed: March 27, 2003
    Publication date: January 15, 2004
    Inventors: Elizabeth Wang, John M. Wozney, Vicki A. Rosen
  • Methods for treatment of periodontal diseases and lesions using bone morphogenetic proteins
    Patent number: 6620406
    Abstract: Methods and compositions are provided for the treatment of periodontal disease and bone lesions. Preferred methods comprise administering a composition containing one or more osteogenic and/or ligament-inducing bone morphogenetic protein and a suitable carrier. The method results in the regeneration of alveolar bone in both a vertical and horizontal direction, and can result in the regeneration of bone, cementum and ligamentous structure between said regenerated bone and the tooth root surface, such that minimal ankylosis and root resorption results. The method and composition are useful for the repair of supraalveolar periodontal lesions and defects, mandibular and maxillary class II and III furcations and interproximal defects, and augmentation of the alveolar ridge of these structures.
    Type: Grant
    Filed: January 27, 1995
    Date of Patent: September 16, 2003
    Assignee: Genetics Institute, LLC.
    Inventors: John M. Wozney, Thomas J. Turek
  • BMP-11 compositions
    Publication number: 20030166910
    Abstract: Purified BMP-11 proteins and processes for producing them are disclosed. Recombinant DNA molecules encoding the BMP-11 proteins are also disclosed. The proteins may be useful in regulating follicle stimulating hormone, such as for contraception. In addition, the proteins may be useful for the induction of bone, cartilage and/or other connective tissue.
    Type: Application
    Filed: July 5, 2002
    Publication date: September 4, 2003
    Applicant: Genetics Institute, Inc.
    Inventors: John M. Wozney, Anthony J. Celeste
  • BMP-6 proteins
    Patent number: 6613744
    Abstract: Purified BMP-6 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and/or cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: March 23, 2001
    Date of Patent: September 2, 2003
    Assignee: Genetics Institute, LLC
    Inventors: John M. Wozney, Elizabeth A. Wang, Vicki A. Rosen, Anthony J. Celeste
  • Receptor proteins
    Patent number: 6610513
    Abstract: Novel serine/threonine receptor proteins and BMP receptor proteins are disclosed, as well as DNA molecules encoding these proteins and methods of using the receptor proteins. Further disclosed are truncated BMP receptor proteins and molecules which act as ligands to these BMP receptor proteins.
    Type: Grant
    Filed: June 5, 2001
    Date of Patent: August 26, 2003
    Assignee: Genetics Institute, LLC.
    Inventors: John M. Wozney, Anthony J. Celeste, R. Scott Thies, Noboru Yamaji
  • Neuronal uses of BMP-11
    Publication number: 20030083252
    Abstract: Purified BMP-11 proteins and processes for producing them are disclosed. Recombinant DNA molecules encoding the BMP-11 proteins are also disclosed. The proteins may be useful in regulating follicle stimulating hormone, such as for contraception. In addition, the proteins may be useful for the induction and/or maintenance of bone, cartilage and/or other connective tissue, and/or neuronal tissue.
    Type: Application
    Filed: December 20, 2001
    Publication date: May 1, 2003
    Applicant: Genetics Institute, Inc.
    Inventors: Anthony J. Celeste, John M. Wozney, R. Scott Thies
  • Novel BMP products
    Publication number: 20030049826
    Abstract: Purified BMP-2 and BMP-4 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair.
    Type: Application
    Filed: March 9, 2001
    Publication date: March 13, 2003
    Applicant: Genetics Institute, Inc.
    Inventors: Elizabeth A. Wang, John M. Wozney, Vicki A. Rosen
  • Tendon-inducing compositions
    Publication number: 20020160494
    Abstract: Compositions of proteins with tendon/ligament-like tissue inducing activity are disclosed. The compositions are useful in the treatment of tendinitis and tendon or ligament defects and in related tissue repair.
    Type: Application
    Filed: August 31, 2001
    Publication date: October 31, 2002
    Inventors: Anthony J. Celeste, John M. Wozney, Vicki A. Rosen, Neil M. Wolfman, Gerald H. Thomsen, Douglas A. Melton
  • Receptor proteins
    Publication number: 20020137133
    Abstract: Novel serine/threonine receptor proteins and BMP receptor proteins are disclosed, as well as DNA molecules encoding said proteins and methods of using the receptor proteins. Further disclosed are truncated BMP receptor proteins and molecules which act as ligands to said BMP receptor proteins.
    Type: Application
    Filed: June 5, 2001
    Publication date: September 26, 2002
    Applicant: Genetics Institute, Inc.
    Inventors: John M. Wozney, Anthony J. Celeste, R. Scott Thies, Noboru Yamaji
  • Bone morphogenetic protein-11 (BMP-11) compositions
    Patent number: 6437111
    Abstract: Purified BMP-11 proteins and processes for producing them are disclosed. Recombinant DNA molecules encoding the BMP-11 proteins are also disclosed. The proteins may be useful in regulating follicle stimulating hormone, such as for contraception. In addition, the proteins may be useful for the induction of bone, cartilage and/or other connective tissue.
    Type: Grant
    Filed: August 28, 1997
    Date of Patent: August 20, 2002
    Assignee: Genetics Institute, Inc.
    Inventors: John M. Wozney, Anthony J. Celeste