Patents by Inventor John M. Wozney

John M. Wozney has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bone morphogenetic protein-3 and compositions
    Patent number: 6432919
    Abstract: Purified BMP-3 proteins and processes for producing them are disclosed. They may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: March 4, 1991
    Date of Patent: August 13, 2002
    Assignee: Genetics Institute, Inc.
    Inventors: Elizabeth A. Wang, John M. Wozney, Vicki Rosen
  • BMP-6 proteins
    Publication number: 20020061577
    Abstract: Purified BMP-6 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and/or cartilage defects and in wound healing and related tissue repair.
    Type: Application
    Filed: March 23, 2001
    Publication date: May 23, 2002
    Inventors: John M. Wozney, Elizabeth A. Wang, Vicki A. Rosen, Anthony J. Celeste
  • Neuronal uses of BMP-11
    Patent number: 6340668
    Abstract: Purified BMP-11 proteins and processes for producing them are disclosed. Recombinant DNA molecules encoding the BMP-11 proteins are also disclosed. The proteins may be useful in regulating follicle stimulating hormone, such as for contraception. In addition, the proteins may be useful for the induction and/or maintenance of bone, cartilage and/or other connective tissue, and/or neuronal tissue.
    Type: Grant
    Filed: October 7, 1999
    Date of Patent: January 22, 2002
    Assignee: Genetics Institute, Inc.
    Inventors: Anthony J. Celeste, John M. Wozney, R. Scott Thies
  • BMP receptor proteins
    Patent number: 6291206
    Abstract: Novel serine/threonine receptor proteins and BMP receptor proteins are disclosed, as well as DNA molecules encoding said proteins and methods of using the receptor proteins. Further disclosed are truncated BMP receptor proteins and molecules which act as ligands to said BMP receptor proteins.
    Type: Grant
    Filed: September 17, 1993
    Date of Patent: September 18, 2001
    Assignee: Genetics Institute, Inc.
    Inventors: John M. Wozney, Anthony J. Celeste, R. Scott Thies, Noboru Yamaji
  • BMP-9 compositions
    Patent number: 6287816
    Abstract: Purified bone morphogenetic protein-9 (BMP-9) proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: June 6, 1994
    Date of Patent: September 11, 2001
    Assignee: Genetics Institute, Inc.
    Inventors: Vicki A. Rosen, John M. Wozney, Anthony J. Celeste, R. Scott Thies, Jeffrey R. Song
  • Tendon-inducing compositions
    Patent number: 6284872
    Abstract: Compositions of proteins with tendon/ligament-like tissue inducing activity are disclosed. The compositions are useful in the treatment of tendinitis and tendon or ligament defects and in related tissue repair.
    Type: Grant
    Filed: February 28, 1997
    Date of Patent: September 4, 2001
    Assignees: Genetics Institute, Inc., President and Fellows of Harvard College
    Inventors: Anthony J. Celeste, John M. Wozney, Vicki A. Rosen, Neil M. Wolfman, Gerald H. Thomsen, Douglas A. Melton
  • BMP-4 products
    Patent number: 6245889
    Abstract: Purified BMP-2 and BMP-4 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: September 9, 1997
    Date of Patent: June 12, 2001
    Assignee: Genetics Institute, Inc.
    Inventors: Elizabeth A. Wang, John M. Wozney, Vicki A. Rosen
  • BMP-6 proteins
    Patent number: 6207813
    Abstract: Purified BMP-6 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and/or cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: November 9, 1998
    Date of Patent: March 27, 2001
    Assignee: Genetics Institute, Inc.
    Inventors: John M. Wozney, Elizabeth A. Wang, Vicki A. Rosen, Anthony J. Celeste
  • Method for healing and repair of connective tissue attachment
    Patent number: 6187742
    Abstract: Methods and compositions are provided for the treatment of defects and disease involving the functional attachment of connective tissue, such as tendon or ligament, to bone. Preferred methods comprise administering a composition containing a bone morphogenetic protein and a suitable carrier. The method results in the regeneration of functional attachment between the connective tissue and bone, such that minimal fibrous or granulation tissue is formed at the interface between the regenerated bone and connective tissue. The method and composition are useful for augmenting tissue grafts in reconstructive surgery. The method and compositions result in closer apposition of bone to the connective tissue at earlier time points and increased strength of fixation at earlier time points.
    Type: Grant
    Filed: March 23, 1999
    Date of Patent: February 13, 2001
    Assignee: Genetics Institute, Inc.
    Inventors: John M. Wozney, Scott A. Rodeo, Jo A. Hannafin, Russell F. Warren
  • BMP-3 products
    Patent number: 6177406
    Abstract: Purified BMP-3 proteins and processes for producing them are disclosed. They may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: September 5, 1997
    Date of Patent: January 23, 2001
    Assignee: Genetics Institute, Inc.
    Inventors: Elizabeth A. Wang, John M. Wozney, Vicki Rosen
  • BMP products
    Patent number: 6150328
    Abstract: Purified BMP-2 and BMP-4 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: June 14, 1991
    Date of Patent: November 21, 2000
    Assignee: Genetics Institute, Inc.
    Inventors: Elizabeth A. Wang, John M. Wozney, Vicki A. Rosen
  • BMP-9 compositions
    Patent number: 6034061
    Abstract: Purified Bone Morphogenetic Protein (BMP)-9 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair, and in hepatic growth and function.
    Type: Grant
    Filed: December 4, 1996
    Date of Patent: March 7, 2000
    Assignee: Genetics Institute, Inc.
    Inventors: Vicki A. Rosen, John M. Wozney, Anthony J. Celeste, Scott R. Thies, Jeffrey R. Song
  • BMP-12 and BMP-13 proteins and DNA encoding them
    Patent number: 6027919
    Abstract: The present invention relates to a novel family of purified proteins, and compositions containing such proteins, which compositions are useful for the induction of tendon/ligament-like tissue formation, wound healing and ligament and other tissue repair. The present invention further relates to DNA molecules, vectors and host cells useful for production of such proteins.
    Type: Grant
    Filed: November 2, 1994
    Date of Patent: February 22, 2000
    Assignee: Genetics Institute, Inc.
    Inventors: Anthony J. Celeste, John M. Wozney, Vicki A. Rosen, Neil M. Wolfman, Gerald H. Thomsen, Douglas A. Melton
  • Methods of administering BMP-5 compositions
    Patent number: 5939388
    Abstract: Purified BMP-5 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and/or cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: January 23, 1997
    Date of Patent: August 17, 1999
    Inventors: Vicki A. Rosen, John M. Wozney, Elizabeth A. Wang
  • Antibodies to bone morphogenetic protein-10 (BMP-10)
    Patent number: 5932216
    Abstract: Purified Bone Morphogenetic Protein-10(BMP-10) proteins and processes for producing them are disclosed. DNA molecules encoding the BMP-10 proteins are also disclosed. The proteins may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: September 10, 1997
    Date of Patent: August 3, 1999
    Inventors: Anthony J. Celeste, John M. Wozney
  • Bone morphogenetic protein (BMP)--6
    Patent number: 5849880
    Abstract: Purified bone morphogenetic protein (BMP)-6 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and/or cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: December 15, 1998
    Assignee: Genetics Institute, Inc.
    Inventors: John M. Wozney, Elizabeth A. Wang, Vicki A. Rosen, Anthony J. Celeste
  • Bone morphogenetic protein-10 (BMP-10) compositions
    Patent number: 5703043
    Abstract: Purified Bone Morphogenetic Protein-10 (BMP-10) proteins and processes for producing them are disclosed. DNA molecules encoding the BMP-10 proteins are also disclosed. The proteins may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: May 30, 1995
    Date of Patent: December 30, 1997
    Assignee: Genetics Institute, Inc.
    Inventors: Anthony J. Celeste, John M. Wozney
  • Bone morphogenetic protein -11 (BMP-11) compositions
    Patent number: 5700911
    Abstract: Purified Bone Morphogenetic Protein-11(BMP-11) proteins and processes for producing them are disclosed. Recombinant DNA molecules encoding the BMP-11 proteins are also disclosed. The proteins may be useful in regulating follicle stimulating hormone, such as for contraception. In addition, the proteins may be useful for the induction of bone, cartilage and/or other connective tissue.
    Type: Grant
    Filed: May 30, 1995
    Date of Patent: December 23, 1997
    Assignee: Genetics Institute, Inc.
    Inventors: John M. Wozney, Anthony J. Celeste
  • DNA encoding and methods for producing BMP-8 proteins
    Patent number: 5688678
    Abstract: Purified cartilage and/or bone inductive proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and/or cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: November 26, 1991
    Date of Patent: November 18, 1997
    Assignee: Genetics Institute, Inc.
    Inventors: Rodney M. Hewick, Jack H. Wang, John M. Wozney, Anthony J. Celeste
  • Bone morphogenetic protein-9 compositions
    Patent number: 5661007
    Abstract: Purified bone morphogenetic protein-9 (BMP-9) proteins and processes for producing them are disclosed, The proteins may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: April 22, 1993
    Date of Patent: August 26, 1997
    Assignee: Genetics Institute, Inc.
    Inventors: John M. Wozney, Anthony J. Celeste