Abstract: Methods are provided in which a network device hosts distinct network access resources that are managed by different entities. The method includes obtaining a request for partitioning one or more network resources of an on-premise network device for connecting one or more endpoints to a first network managed by a first entity. The on-premise network device connects one or more endpoints to a second network managed by a different entity. The method further involves partitioning, based on the request, the one or more network resources and connecting the one or more endpoints to the first network using the one or more network resources. The one or more network resources are managed by the first entity while at least one other network resource of the on-premise network device is managed by the different entity and is associated with connecting the one or more endpoints to the second network.

Abstract: Various embodiments describe communication systems for implementing high-speed transmission systems using waveguide-mode transmission over wires. In certain examples, a communication system uses wire pairs as “waveguides” that transmit data at high frequencies and speeds. The data is transmitted through wave propagation that takes various forms, such as surface waves and Total Internal Reflection (TIR) waves.

Abstract: A method including detecting, in a written electronic communication, an input sentence satisfying a readability metric threshold. The method also includes transforming, by a sentence transformer model, the input sentence to output suggested sentences. The method also includes evaluating the suggested sentences along a set of acceptability criteria. The method also includes determining, based on the evaluating, that the set of acceptability criteria is satisfied. The method also includes modifying, based on determining that the set of acceptability criteria is satisfied, the written electronic communication with the suggested sentences to obtain a modified written electronic communication. The method also includes returning the modified written electronic communication.

Abstract: A technique may include receiving, by a management service a plurality of instance configurations from a client device. The technique may then include receiving, by the management service, information identifying a launch request for a compute instance. The technique may include determining, by the management service, one or more candidate shapes for the compute instance based at least in part on the plurality of instance configurations. The technique may include selecting, by the management service and from the one or more candidate shapes, a launch shape for the compute instance and launching the compute instance using the launch shape. The technique may then include providing, the client device access to the compute instance, launched based on the launch shape.

Abstract: Embodiments of secondary batteries having electrode assemblies are provided. A secondary battery can comprise an electrode assembly having a stacked series of layers, the stacked series of layers having an offset between electrode and counter-electrode layers in a unit cell member of the stacked series. A set of constraints can be provided with a primary constraint system with first and second primary growth constraints separated from each other in a longitudinal direction, and connected by at least one primary connecting member, and a secondary constraint system comprises first and second secondary growth constraints separated in a second direction and connected by members of the stacked series of layers. The primary constraint system may at least partially restrain growth of the electrode assembly in the longitudinal direction, and the secondary constraint system may at least partially restrain growth in the second direction that is orthogonal to the longitudinal direction.

Abstract: The present disclosure provides methods for genetically engineering T cells, such as CD4+ T cells, for use in cell therapy. In some aspects, the provided methods include one or more steps for incubating the cells under stimulating conditions, introducing a recombinant polypeptide to the cells through transduction or transfection, and cultivating the cells under conditions that promote proliferation and/or expansion. In some aspects, the incubation and/or the cultivation is performed in the presence of recombinant IL-2. In some aspects, the provided methods are an efficient, reliable means to produce genetically engineered T cells with a high degree of success.

Abstract: A system and method for authorization policy validation. A validator takes as input an authorization policy to be analyzed and a schema that specifies entity types and their attributes, types of entity parents in an entity hierarchy, and which entity types can be used with which actions. The validator checks that the policy conforms to the schema. If the check passes, then the policy is guaranteed to be free of both type errors and attribute access errors for any input that conforms to the schema.

Abstract: Simulation software and planning tools are provided that can simulate treatment, allowing a user to identify preferred poses or positions of a histotripsy therapy transducer array for a given treatment location. The planning tools can identify obstructed transducer elements for a given pose/position, and can provide pressure simulations to estimate driving voltages required to generate cavitation at the treatment location. A digital treatment plan made with the planning tool can transferred to a histotripsy system for use during the therapy procedure. A histotripsy therapy system configured for the treatment of tissue is provided, which may implement the digital treatment plan from the simulation software and planning tools.

Abstract: Devices, systems, and methods are provided for registering image data with robotic data for image-guided robotic catheters and other elongate bodies. Fluid drive systems can be used to provide robotically coordinated motion. Precise control over catheter-supported tools is enhanced by alignment of fluoroscopic and ultrasound image data, particularly for structural heart and other therapies in which the catheter will interact with soft tissues. A marker plate having a planar array of machine-readable 2D barcode markers may facilitate alignment of image and robotic data. Determining an ultrasound-based pose of a component in the ultrasound image field allows that component to effectively a fiducial for alignment.

Abstract: An ultrasound imaging system, a method, and computer-implemented media. The system includes: context determination circuitry (CDC) to generate context signals based on one or more ultrasound imaging session contexts of an ultrasound imaging session; a memory storing a context information engine (CIE); circuitry coupled to the memory and adapted to execute the CIE to determine one or more context parameters of the ultrasound imaging session based on the context signals from the CDC; and processing circuitry to: access the one or more context parameters before or during the ultrasound imaging session; and determine one or more ultrasound imaging settings of the ultrasound imaging session based on the one or more context parameters; and cause the one or more settings to be implemented for the ultrasound imaging session.

Abstract: A device for providing respiratory gases comprises a blower configured to receive a first gas from a first gas flow path and generate a flow of a first gas provided through a first gases outlet of the blower; a second gas flow path configured to receive a flow of a second gas and provide the flow of the second gas through a second gases outlet; and a mixing chamber configured to receive a flow of the first gas from the first gases outlet and a flow of the second gas from the second gases outlet. The received gases are configured to mix in the mixing chamber to form a mixed gas. The received gases are configured to travel in a mixing flow direction in the mixing chamber towards a mixed gases inlet, wherein mixed gas exits the mixing chamber via the mixed gases inlet providing flow to a mixed gas flow path.

Abstract: The invention relates to substituted heterocycles of the general formula I, and the use of the compounds of the present invention for the treatment and/or prevention of hyperproliferative diseases and disorders in mammals, especially humans, and pharmaceutical compositions containing such compound.

Abstract: Provided herein are compounds of Formula (I), Formula (II), Formula (III), a compound selected from any of the compounds in Table 1, Table 2, Table 3, Table 4 or a pharmaceutically acceptable salt or deuterated form thereof, wherein R1, R2, R3, R4, RD, RG, p and q are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of formula (I), or a compound selected from any of the compounds in Table 1, Table 2, Table 3, Table 4 or pharmaceutically acceptable salt or deuterated form thereof, and methods of using a compound of formula (I), Formula (II), Formula (III), or pharmaceutically acceptable salt or deuterated form thereof, e.g., in treating 5-HT2A receptor associated diseases or disorders.

Abstract: Provided herein are compounds of Formula (I), a compound selected from any of the compounds in Table 1, Table 2, Table 3, or a pharmaceutically acceptable salt or deuterated form thereof, wherein R1, R2, R3 and R4 are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of formula (I), or a compound selected from any of the compounds in Table 1, Table 2, Table 3, or pharmaceutically acceptable salt or deuterated form thereof, and methods of using a compound of formula (I) or pharmaceutically acceptable salt or deuterated form thereof, e.g., in treating 5-HT2A receptor associated diseases or disorders.

Abstract: Embodiments herein are generally directed to spinal implants, systems, apparatuses, and components thereof that can be used in spinal fusion and/or stabilization procedures, as well as methods of installation. The spinal implants may include an intervertebral spacer and a plate member.