Patents by Inventor John McMichael

John McMichael has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240111117
    Abstract: An alignment apparatus for aligning components of an optical assembly include a chuck configured to support the optical assembly thereon, and an adjustable flexure assembly disposed around the chuck. The adjustable flexure assembly includes a plurality of flexures. The plurality of flexures are positioned relative to the chuck such that each of the plurality of flexures contact the optical assembly when the optical assembly is positioned on the chuck.
    Type: Application
    Filed: December 12, 2023
    Publication date: April 4, 2024
    Inventors: Robert Dennis Grejda, Kevin John Magierski, Brian Monroe McMaster, Todd Robert McMichael
  • Publication number: 20230398090
    Abstract: Disclosed herein are methods of treating a coronavirus infection by administration of ethyl mercury or thiol derivative thereof in an amount effective to treat the coronavirus infection.
    Type: Application
    Filed: March 24, 2021
    Publication date: December 14, 2023
    Inventor: John McMichael
  • Patent number: 11564958
    Abstract: A method is provided for treatment of symptoms of Ehlers-Danlos Syndromes comprising administration of a composition comprising rubeola virus, histamine and collagen.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: January 31, 2023
    Assignee: RESOLYS BIO, INC.
    Inventor: John McMichael
  • Publication number: 20200338147
    Abstract: A method is provided for treatment of symptoms of Ehlers-Danlos Syndromes comprising administration of a composition comprising rubeola virus, histamine and collagen.
    Type: Application
    Filed: December 21, 2018
    Publication date: October 29, 2020
    Inventor: John McMichael
  • Patent number: 10213480
    Abstract: Disclosed herein is a method of inhibiting microglial cell migration in the brain of a mammalian subject in need thereof, including subjects suffering from the symptoms of traumatic brain injury (TBI) and subjects suffering from a hematoma in the brain comprising administering an effective amount streptolysin O (SLO) wherein microglial migration is inhibited providing therapeutic benefits to subjects suffering from diseases characterized by microglial cell migration and activation.
    Type: Grant
    Filed: October 4, 2017
    Date of Patent: February 26, 2019
    Assignee: BEECH TREE LABS, INC.
    Inventor: John McMichael
  • Publication number: 20180028602
    Abstract: Disclosed herein is a method of inhibiting microglial cell migration in the brain of a mammalian subject in need thereof, including subjects suffering from the symptoms of traumatic brain injury (TBI) and subjects suffering from a hematoma in the brain comprising administering an effective amount streptolysin O (SLO) wherein microglial migration is inhibited providing therapeutic benefits to subjects suffering from diseases characterized by microglial cell migration and activation.
    Type: Application
    Filed: October 4, 2017
    Publication date: February 1, 2018
    Inventor: John McMichael
  • Patent number: 9682058
    Abstract: Disclosed herein are methods of treating viral infections by administration of ethyl mercury or thiol derivative thereof in an amount effective to treat the viral infection.
    Type: Grant
    Filed: March 18, 2011
    Date of Patent: June 20, 2017
    Assignee: BEECH TREE LABS, INC.
    Inventor: John McMichael
  • Publication number: 20150320849
    Abstract: The present invention relates to a treatment for mammalian subjects suffering from a central nervous system (CNS) disorder by administering a composition comprising an Borrelia burgdorferi antigen at a sub-vaccine level effective to alleviate symptoms of the CNS disorder.
    Type: Application
    Filed: May 5, 2015
    Publication date: November 12, 2015
    Inventor: John McMichael
  • Patent number: 8980826
    Abstract: The present invention relates to a method of promoting bronchodilation by administration of streptolysin O to a subject in need thereof.
    Type: Grant
    Filed: February 27, 2013
    Date of Patent: March 17, 2015
    Assignee: Beech Tree Labs, Inc.
    Inventor: John McMichael
  • Publication number: 20140194368
    Abstract: The invention is directed to methods of treating cancer by administration of heat shock protein 70 (Hsp70) to the subject suffering from cancer.
    Type: Application
    Filed: January 4, 2013
    Publication date: July 10, 2014
    Applicant: Beech Tree Labs, Inc.
    Inventor: John McMichael
  • Publication number: 20140121256
    Abstract: The present invention relates to a treatment of muscle weakness resulting from a disease state or injury in a subject suffering therefrom by administering a composition including histamine in an amount effective to alleviate muscle weakness in the subject suffering therefrom.
    Type: Application
    Filed: October 24, 2013
    Publication date: May 1, 2014
    Applicant: BEECH TREE LABS, INC.
    Inventor: John McMichael
  • Publication number: 20140120191
    Abstract: Disclosed herein are methods and compositions for treating a disorder associated with sequestered bacteria in a mammalian subject comprising the step of administering to the subject a combination therapy comprising streptolysin O and antibiotic therapy in an amount effective to treat the disorder.
    Type: Application
    Filed: January 26, 2012
    Publication date: May 1, 2014
    Applicant: BEECH TREE LABS INC.
    Inventor: John McMichael
  • Patent number: 8367610
    Abstract: A method for administering nerve growth factor to treat cravings is provided. Pharmaceutical compositions for the treatment of cravings comprising nerve growth factor are also provided.
    Type: Grant
    Filed: October 5, 2009
    Date of Patent: February 5, 2013
    Assignee: Beech Tree Labs, Inc.
    Inventor: John McMichael
  • Publication number: 20110230554
    Abstract: Disclosed herein are methods of treating viral infections by administration of ethyl mercury or thiol derivative thereof in an amount effective to treat the viral infection.
    Type: Application
    Filed: March 18, 2011
    Publication date: September 22, 2011
    Applicant: BEECH TREE LABS, INC.
    Inventor: John McMichael
  • Publication number: 20100144602
    Abstract: The invention provides a method for administering streptolysin O for treatment of various conditions including connective tissue disorders, reproductive fibroses and conditions mediated by the CD44 receptor. The invention also provides methods for protecting nerve cells from the effects of neurotoxic agents by the administration of streptolysin O.
    Type: Application
    Filed: December 7, 2009
    Publication date: June 10, 2010
    Applicant: Milkhaus Laboratory, Inc.
    Inventor: John McMichael
  • Publication number: 20100093631
    Abstract: A method for administering nerve growth factor to treat cravings is provided. Pharmaceutical compositions for the treatment of cravings comprising nerve growth factor are also provided.
    Type: Application
    Filed: October 5, 2009
    Publication date: April 15, 2010
    Inventor: John McMichael
  • Patent number: 7629312
    Abstract: The invention provides a method for administering streptolysin O for treatment of various conditions including connective tissue disorders, reproductive fibroses and conditions mediated by the CD44 receptor. The invention also provides methods for protecting nerve cells from the effects of neurotoxic agents by the administration of streptolysin O.
    Type: Grant
    Filed: March 20, 2007
    Date of Patent: December 8, 2009
    Assignee: Milkhaus Laboratory, Inc.
    Inventor: John McMichael
  • Publication number: 20080182789
    Abstract: Methods and compositions for treating pulmonary fibrosis are presented. Methods comprise administering compositions comprising DNA and streptolysin O to a subject in a manner so as not to effect gene transfer.
    Type: Application
    Filed: December 28, 2007
    Publication date: July 31, 2008
    Applicant: Milkhaus Laboratory, Inc.
    Inventor: John McMichael
  • Publication number: 20070270347
    Abstract: Method for administering nerve growth factor to treat various psychological conditions such as of depression, bi-polar disorders, anxiety disorders, panic attacks, agoraphobia, and attention deficit syndrome, and alleviate symptoms associated with premenstrual syndrome (PMS), premenstrual dysphoric disorder (PMDD), sleep disorders, tension headaches, and constipation that arise as complications from a psychological condition. Also provided are methods of treating constipation comprising administering nerve growth factor in amount effective to treat constipation. Pharmaceutical compositions for the treatment of constipation comprising nerve growth factor are also provided.
    Type: Application
    Filed: June 25, 2007
    Publication date: November 22, 2007
    Applicant: Milkhaus Laboratory, Inc.
    Inventor: John McMichael
  • Publication number: 20070219119
    Abstract: The invention provides a method for administering streptolysin O for treatment of various conditions including connective tissue disorders, reproductive fibroses and conditions mediated by the CD44 receptor. The invention also provides methods for protecting nerve cells from the effects of neurotoxic agents by the administration of streptolysin O.
    Type: Application
    Filed: March 20, 2007
    Publication date: September 20, 2007
    Applicant: MILKHAUS LABORATORY, INC.
    Inventor: John McMichael