Abstract: Embodiments of the present invention provide a novel and non-obvious method, system and computer program product for pre-routing network security for cloud computing. In an embodiment of the invention, a pre-routing network security method for cloud computing includes receiving in a routing component, such as a load balancer, of a cloud computing environment that includes at least two different virtualized containers, a stream of packets targeting a destination network address and, before processing the stream of packets in the routing component, diverting the stream of packets to a packet inspector executing in one of the virtualized containers. Then, only a fraction of the packets of the diverted stream of packets are received in the routing component from the packet inspector, and, the fraction of the packets are then processed in the router such that the fraction of the packets are routed to the destination network address.

Abstract: The present invention relates to a combination treatment which comprises (a) at least one ERK inhibitor preferably Compound B as described herein, and (b) a c-RAF inhibitor or a pharmaceutically acceptable salt thereof, preferably Compound A, which may be combined into a single pharmaceutical composition or prepared for separate or sequential administration. It includes a c-RAF inhibitor and an ERK inhibitor prepared for simultaneous, separate or sequential administration for the treatment of a proliferative disease, particularly an advanced solid tumor that harbors a Mitogen-activated protein kinase (MAPK) alteration, and includes methods of using these compounds in combination as well as a commercial package comprising such combination.

Abstract: Embodiments described herein include systems and methods for providing a management interface for controlling multiple households. The management interface may be provided as an application on a mobile device or as an Internet webpage. An example implementation involves a device displaying representations of: a plurality of households; an indication of a selected household; one or more zones within the selected household; and a representation of media being played by a selected zone of the one or more zones. While displaying the representations, the device receives, from a server, data indicating updated information associated with the plurality of households; and, in response, updates the graphical display to display at least an updated representation of media being played by the selected zone.

Abstract: A microelectronic package may be fabricated having at least one microelectronic die attached to a microelectronic substrate, wherein the microelectronic substrate includes at least one notch formed in at least one side thereof. The microelectronic dice may be attached to a first surface of the microelectronic substrate and in electronic communication with a bond pad on a second surface of the microelectronic substrate with a bond wire which extends through the notch in the microelectronic substrate.

Abstract: A nerve monitoring system facilitates monitoring an integrity of a nerve.

Abstract: Embodiments described herein include systems and methods for providing a management interface for controlling multiple households. The management interface may be provided as an application on a mobile device or as an Internet webpage. An example implementation involves a device displaying representations of: a plurality of households; an indication of a selected household; one or more zones within the selected household; and a representation of media being played by a selected zone of the one or more zones. While displaying the representations, the device receives, from a server, data indicating updated information associated with the plurality of households; and, in response, updates the graphical display to display at least an updated representation of media being played by the selected zone.

Abstract: The present invention relates to a pharmaceutical combination comprising dabrafenib, trametinib and an Erk-inhibitor; pharmaceutical compositions comprising the same; and methods of using such combinations and compositions in the treatment or prevention of conditions in which MAPK pathway inhibition is beneficial, for example, in the treatment of cancers.

Abstract: The present invention relates to a combination treatment which comprises (a) at least one ERK inhibitor preferably Compound B as described herein, and (b) a c-RAF inhibitor or a pharmaceutically acceptable salt thereof, preferably Compound A, which may be combined into a single pharmaceutical composition or prepared for separate or sequential administration. It includes a c-RAF inhibitor and an ERK inhibitor prepared for simultaneous, separate or sequential administration for the treatment of a proliferative disease, particularly an advanced solid tumor that harbors a Mitogen-activated protein kinase (MAPK) alteration, and includes methods of using these compounds in combination as well as a commercial package comprising such combination.

Abstract: An antenna with adjustable tilt angle includes: a mounting structure; an antenna mount fixed to the mounting structure; an antenna mounted to the antenna mount, the antenna configured to produce an antenna beam; a remote electrical tilt (RET) unit operatively associated with the antenna to adjust a pointing tilt angle of the antenna beam; a tilt pointing direction sensor mounted to the antenna, the pointing direction tilt sensor configured to detect the a pointing angle of the antenna relative to a baseline standard; and a controller operatively connected with the RET unit and the pointing direction tilt sensor, the controller configured to receive signals from the pointing direction tilt sensor and transmit signals to the RET unit to adjust the tilt pointing angle of the antenna beam based on the detected angle of the antenna.

Abstract: The present disclosure relates to anti-CD32b antibody molecules which selectively bind human CD32b. Also provided herein are compositions comprising anti-CD32b antibody molecules in combination with other compounds, and methods of using the combinations to treat subject with cancer.

Abstract: Embodiments of the present invention provide a novel and non-obvious method, system and computer program product for pre-routing network security for cloud computing. In an embodiment of the invention, a pre-routing network security method for cloud computing includes receiving in a routing component, such as a load balancer, of a cloud computing environment that includes at least two different virtualized containers, a stream of packets targeting a destination network address and, before processing the stream of packets in the routing component, diverting the stream of packets to a packet inspector executing in one of the virtualized containers. Then, only a fraction of the packets of the diverted stream of packets are received in the routing component from the packet inspector, and, the fraction of the packets are then processed in the router such that the fraction of the packets are routed to the destination network address.

Abstract: The present invention relates to anti-cKIT antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.

Abstract: Embodiments described herein include systems and methods for providing a management interface for controlling multiple households. The management interface may be provided as an application on a mobile device or as an Internet webpage. An example implementation involves a device displaying representations of: a plurality of households; an indication of a selected household; one or more zones within the selected household; and a representation of media being played by a selected zone of the one or more zones. While displaying the representations, the device receives, from a server, data indicating updated information associated with the plurality of households; and, in response, updates the graphical display to display at least an updated representation of media being played by the selected zone.

Abstract: The present invention relates to anti-cKIT antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.

Abstract: Examples disclosed herein relate to a device that has a chassis that can transition from a factory security state to a production security state. A visible object can be removed from the outside of the chassis to trigger the change in state. A BMC can change the state from the factory security state to the production security state based on detection of a physical trigger. The factory security state includes an application programming interface (API) that is enabled and the production security state has the API disabled.

Abstract: Embodiments described herein include systems and methods for providing a management interface for controlling multiple households. The management interface may be provided as an application on a mobile device or as an Internet webpage. An example implementation involves a device displaying representations of: a plurality of households; an indication of a selected household; one or more zones within the selected household; and a representation of media being played by a selected zone of the one or more zones. While displaying the representations, the device receives, from a server, data indicating updated information associated with the plurality of households; and, in response, updates the graphical display to display at least an updated representation of media being played by the selected zone.

Abstract: The present invention relates to a combination treatment which comprises (a) at least one ERK inhibitor preferably Compound B as described herein, and (b) a c-RAF inhibitor or a pharmaceutically acceptable salt thereof, preferably Compound A, which may be combined into a single pharmaceutical composition or prepared for separate or sequential administration. It includes a c-RAF inhibitor and an ERK inhibitor prepared for simultaneous, separate or sequential administration for the treatment of a proliferative disease, particularly an advanced solid tumor that harbors a Mitogen-activated protein kinase (MAPK) alteration, and includes methods of using these compounds in combination as well as a commercial package comprising such combination.

Abstract: The present invention relates to anti-FGFR2 antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.

Abstract: Embodiments described herein include systems and methods for providing a management interface for controlling multiple households. The management interface may be provided as an application on a mobile device or as an Internet webpage. An example implementation involves a device displaying representations of: a plurality of households; an indication of a selected household; one or more zones within the selected household; and a representation of media being played by a selected zone of the one or more zones. While displaying the representations, the device receives, from a server, data indicating updated information associated with the plurality of households; and, in response, updates the graphical display to display at least an updated representation of media being played by the selected zone.

Abstract: A technology is described for distributing a configuration file to network addressable devices. An example method may include receiving a configuration customization that is to be applied to the configuration settings of a non-configured network addressable device. A configuration file may be updated with the configuration customization. A request may be received to transmit the configuration file so that the configuration file may be applied to the configuration settings of the non-configured network addressable device.