Abstract: Herein are antibodies or antigen-binding fragments specifically binding to GPRC5D. Additionally, monovalent antibodies or antigen-binding fragments specifically binding to GPRC5D are also included. The Fc region of these antibodies contains K248E and T437R mutations (designated as “RE mutations”) per the EU numbering system. The described antibodies, expressed in host cells that lack fucosylation capabilities, exhibit enhanced antibody-dependent cellular cytotoxicity (ADCC) and enhanced complement-dependent cytotoxicity (CDC).

Abstract: A blending device (2) for blending a sample held in a sealable open mouthed sample bag comprises a bag receiving portion (6). The blending device (2) also includes a kneading arrangement (20) for acting on a wall of a sample bag (8) disposed in the bag receiving portion (6) so as to blend a sample contained in the bag (8). A bag manipulation arrangement (13) or a bag support (28) may also be provided.

Abstract: A blending device (2) for blending a sample held in a sealable open mouthed sample bag comprises a bag receiving portion (6). The blending device (2) also includes a kneading arrangement (20) for acting on a wall of a sample bag (8) disposed in the bag receiving portion (6) so as to blend a sample contained in the bag (8). A bag manipulation arrangement (13) or a bag support (28) may also be provided.

Abstract: The instant invention relates to mesogenic systems comprising a) a polymeric component, component A, obtained or obtainable from polymerisation of a precursor comprising one or more mesogenic mono-reactive compounds, one or more di-reactive compounds, which optionally are also mesogenic compounds and optionally a photo-initiator and a low molecular weight component, component B, comprising one or more mono-reactive, mesogenic compounds, one or more mesogenic compounds and one or more chiral dopants, exhibiting a Blue Phase, as well as to the use of these systems in deices and to these devices.

Abstract: The invention generally relates to a facility wide sorting and/or sequencing system for improving product processing operations and, more particularly, to a facility wide system and related functionality for simultaneously sorting and sequencing mixed mail pieces such as, for example, flats and letter mail pieces. The flats and letter mail pieces are placed in frames so that all types of mail pieces can be sorted and/or sequenced simultaneously through merging and diverting a stream of filled trays into and out of different streams at a full or substantially full transport speed.

Abstract: The invention generally relates to a facility wide sorting and/or sequencing system for improving product processing operations and, more particularly, to a facility wide system and related functionality for simultaneously sorting and sequencing mixed mail pieces such as, for example, flats and letter mail pieces. The flats and letter mail pieces are placed in frames so that all types of mail pieces can be sorted and/or sequenced simultaneously through merging and diverting a stream of filled trays into and out of different streams at a full or substantially full transport speed.

Abstract: A blending device (2) for blending a sample held in a sealable open mouthed sample bag comprises a bag receiving portion (6). The blending device (2) also includes a kneading arrangement (20) for acting on a wall of a sample bag (8) disposed in the bag receiving portion (6) so as to blend a sample contained in the bag (8). A bag manipulation arrangement (13) or a bag support (28) may also be provided.

Abstract: The invention generally relates to a facility wide sorting and/or sequencing system for improving product processing operations and, more particularly, to a facility wide system and related functionality for simultaneously sorting and sequencing mixed mail pieces such as, for example, flats and letter mail pieces. The flats and letter mail pieces are placed in frames so that all types of mail pieces can be sorted and/or sequenced simultaneously through merging and diverting a stream of filled trays into and out of different streams at a full or substantially full transport speed.

Abstract: The instant invention relates to mesogenic systems comprising a) a polymeric component, component A, obtained or obtainable from polymerisation of a precursor comprising one or more mesogenic mono-reactive compounds, one or more di-reactive compounds, which optionally are also mesogenic compounds and optionally a photo-initiator and a low molecular weight component, component B, comprising one or more mono-reactive, mesogenic compounds, one or more mesogenic compounds and one or more chiral dopants, exhibiting a Blue Phase, as well as to the use of these systems in deices and to these devices.

Abstract: The invention relates to new cyclohexylene reactive mesogens (RM), polymers derived thereof, liquid crystal (LC) media comprising them, and the use of the compounds, polymers and liquid crystalline media in optical, electrooptical, electronic, semiconducting or luminescent components or devices, in decorative, security, cosmetic or diagnostic applications, especially in the polymer stabilised blue phase.

Abstract: The instant invention relates to mesogenic systems comprising a) a polymeric component, component A, obtained or obtainable from polymerization of a precursor comprising one or more mesogenic mono-reactive compounds, one or more di-reactive compounds, which optionally are also mesogenic compounds and optionally a photo-initiator and a low molecular weight component, component B, comprising one or more mono-reactive, mesogenic compounds, one or more mesogenic compounds and one or more chiral dopants, exhibiting a Blue Phase, as well as to the use of these systems in deices and to these devices.

Abstract: The instant invention relates to mesogenic systems comprising a) a polymeric component, component A, obtained or obtainable from polymerisation of a precursor comprising one or more mesogenic mono-reactive compounds, one or more di-reactive compounds, which optionally are also mesogenic compounds and optionally a photo-initiator and a low molecular weight component, component B, comprising one or more mono-reactive, mesogenic compounds, one or more mesogenic compounds and one or more chiral dopants, exhibiting a Blue Phase, as well as to the use of these systems in deices and to these devices.

Abstract: The instant invention relates to mesogenic media comprising one or more compounds which comprise two or more mesogenic groups two of which are linked to the ortho-positions of an aromatic ring, preferably of formula (I) wherein the parameters are as specified in the text, preferably the instant invention relates to mesogenic media showing a blue phase and their use in electro-optical light modulation elements and their respective use in displays, as well as to such devices. The instant invention further relates to compounds of formula (I).

Abstract: The invention generally relates to a facility wide sorting and/or sequencing system for improving product processing operations and, more particularly, to a facility wide system and related functionality for simultaneously sorting and sequencing mixed mail pieces such as, for example, flats and letter mail pieces. The flats and letter mail pieces are placed in frames so that all types of mail pieces can be sorted and/or sequenced simultaneously through merging and diverting a stream of filled trays into and out of different streams at a full or substantially full transport speed.

Abstract: The instant invention relates to mesogenic systems comprising a) a polymeric component, component A, obtained or obtainable from polymerisation of a precursor comprising one or more mesogenic mono-reactive compounds, one or more di-reactive compounds, which optionally are also mesogenic compounds and optionally a photo-initiator and a low molecular weight component, component B, comprising one or more mono-reactive, mesogenic compounds, one or more mesogenic compounds and one or more chiral dopants, exhibiting a Blue Phase, as well as to the use of these systems in deices and to these devices.

Abstract: The instant invention relates to mesogenic systems comprising a) a polymeric component, component A, obtained or obtainable from polymerisation of a precursor comprising one or more mesogenic mono-reactive compounds, one or more di-reactive compounds, which optionally are also mesogenic compounds and optionally a photo-initiator and a low molecular weight component, component B, comprising one or more mono-reactive, mesogenic compounds, one or more mesogenic compounds and one or more chiral dopants, exhibiting a Blue Phase, as well as to the use of these systems in deices and to these devices.

Abstract: The invention relates to new cyclohexylene reactive mesogens (RM), polymers derived thereof, liquid crystal (LC) media comprising them, and the use of the compounds, polymers and liquid crystalline media in optical, electrooptical, electronic, semiconducting or luminescent components or devices, in decorative, security, cosmetic or diagnostic applications, especially in the polymer stabilised blue phase.

Abstract: The invention relates to a method of preparing a birefringent marking by printing a polymerisable liquid crystal material onto at least one side of a substrate and polymerising the liquid crystal material, to a birefringent marking obtained by this method, and to the use of the birefringent marking for decorative, security, authentification and identification applications.

Abstract: The present invention relates to a liquid crystalline mixture comprising a) 1-25% by weight of at least one compound of the formula I b) 5-80% by weight of at least one compound of the formula II c) and optionally 1-20% by weight of at least one chiral compound with a HTP of ?20 ?m, wherein R11, A11, Z11, A12, Z12, L11, L12, L13, L14, Z13, A13, Z14, A14, X11, a, b, c, d, R12, A1, Z1, A2, Z2, A3, L1, L2, X12, m and n have the meanings given in claim 1 and their use in TFT, TN, IPS applications and expecially for devices utilizing electro-optical effects in an optically isotropic state.