Abstract: Electrostimulation systems and methods are contemplated in which a high current level, charge balanced alternating current electrical signal is generated for delivery to a patient's brain for the treatment of mild traumatic brain injury (mTBI) and post-concussion symptoms. By stimulating the brain with a charged balanced stimulation current with a stimulation current envelope defining one or more series of pulses at particular frequencies and durations designed to evoke metabolic response in the neurons, significant improvements in efficacy and reductions in symptoms and pain may be achieved relative to earlier treatment techniques. Further advantages, especially in promoting neural entrainment, may be realized as well via utilizing multiple series of pulses at different frequencies, and via the dynamic adjustment of the stimulation waveform via incorporation of feedback signals in order to maintain charge balance in real-time.

Abstract: Systems and methods are provided for processing a set of multiple serially acquired magnetic resonance spectroscopy (MRS) free induction decay (FID) frames from a multi-frame MRS acquisition series from a region of interest (ROI) in a subject, and for providing a post-processed MRS spectrum. Processing parameters are dynamically varied while measuring results to determine the optimal post-processed results. Spectral regions opposite water from chemical regions of interest are evaluated and used in at least one processing operation. Frequency shift error is estimated via spectral correlation between free induction decay (FID) frames and a reference spectrum. Multiple groups of FID frames within the acquired set are identified to different phases corresponding with a phase step cycle of the acquisition. Baseline correction is also performed via rank order filter (ROF) estimate and a polynomial fit.

Abstract: Methods and systems disclosed herein enable tracking user actions by generating different visually scannable codes (e.g., QR codes) for combinations of user, operator, and action(s). Each visually scannable code may be stored with user action data and an operator identifier and linked to another visually scannable code corresponding to the user. When a visually scannable code is scanned, all data associated with the visually scannable code and data associated with other linked visually scannable codes is generated for display. By generating the visually scannable codes and storing the codes in a linked state, the system is able to provide quick and efficient data retrieval.

Abstract: An atomic object confined in a particular region of a confinement apparatus is cooled via a simultaneous sideband and Doppler laser cooling operation. A controller controls first and second manipulation sources to provide first and second two-photon transition manipulation signals to the particular region. The controller controls a third manipulation source to provide a repump manipulation signal to the particular region. The first and second two-photon transition manipulation signals are collectively configured to cause the atomic object to undergo a red sideband transition from a first ground state to a second ground state. The repump manipulation signal is configured to repump the atomic object from the second ground state to the first ground state via an excited state. The repump manipulation signal is red detuned from a transition from the second ground state to the excited state by a repump detuning configured to cause Doppler cooling of the atomic object.

Abstract: Provided are compounds of Formula (I): wherein R1, R2, X, Ring A, Ring B, and Ring C are as defined herein. Compounds of Formula (I) are useful as inhibitors of DNA-PK. Also provided are pharmaceutical compositions comprising said compounds and methods of using the compounds and compositions in the treatment of various diseases, conditions, and disorders.

Abstract: The disclosure relates to systems and methods for improving the manufacturing of silk solutions and powders containing silk fibroin obtained from silkworm cocoons. The systems include a reactor vessel to degum, rinse, and dissolve the silk fibroin protein from silk inputs to obtain a purified silk fibroin-based solution. The reactor vessel may include a combination of inputs and outputs for introducing and removing different components used or generated during the disclosed processes. The systems may include any combination of heat exchangers, holding tanks, filtration modules, and post-treatment equipment as necessary to obtain the silk powder. The solutions and powders can be used to improve the post-harvest preservation of perishables and to improve the performance of packaging, including biodegradable packaging.

Abstract: A compliant end effector includes a robot mounting bracket and a component support member. The component support member includes a side surface and a top surface. A component clamping system includes a first clamp member operable to move toward the side surface of the component support member and a second clamp member operable to move toward the top surface of the component support member. A controller is operatively connected to the clamping system. The controller is configured to engage the first and second clamp members as the component gripping and manipulating system is in a set position and release the first clamp member and the second clamp member allowing a portion of a component held by the component clamping system to move with one or more degrees of freedom when the component gripping and manipulating system is moving to the set position.

Abstract: Methods of forming an optical fiber assembly involve placing an adhesive in a ferrule assembly, heating the ferrule assembly through thermal induction, inserting an optical fiber into the ferrule bore during or after the heating step, and securing the optical fiber to the ferrule assembly using the adhesive. The thermal induction causes the adhesive to efficiently take or maintain a melted form to allow the optical fiber insertion.

Abstract: Sheet product dispensers provided herein include a spindle mounted to a spindle mounting arm. A pressure plate positioned at least partially within the spindle mounting arm aligns with a roll of sheet product installed on the spindle. When the spindle mounting arm is in a dispensing state and the pressure plate is unextended, the pressure plate is configured to prevent rotation of the spindle mounting arm to a loading state, and, when the spindle mounting arm is in the dispensing state and the pressure plate is extended, the pressure plate is configured to allow transition of the spindle mounting arm to the loading state. Force from the roll of sheet product causes the pressure plate to remain unextended, and a sufficient amount of sheet product from the roll of sheet product having been depleted removes the force such that the pressure plate becomes extended.

Abstract: A method comprising: receiving, at a vector processor, a request to store data; performing, by the vector processor, one or more transforms on the data; and directly instructing, by the vector processor, one or more storage device to store the data; wherein performing one or more transforms on the data comprises: erasure encoding the data to generate n data fragments configured such that any k of the data fragments are usable to regenerate the data, where k is less than n; and wherein directly instructing one or more storage device to store the data comprises: directly instructing the one or more storage devices to store the plurality of data fragments.

Abstract: An electrostatic chuck for a substrate processing system is provided and includes a baseplate, an intermediate layer disposed on the baseplate, and a top plate. The top plate is bonded to the baseplate via the intermediate layer and is configured to electrostatically clamp to a substrate. The top plate includes a monopolar clamping electrode and seals. The monopolar clamping electrode includes a groove opening pattern with coolant gas groove opening sets. The seals separate coolant gas zones. The coolant gas zones include four or more coolant gas zones. Each of the coolant gas zones includes distinct coolant gas groove sets. The top plate includes the distinct coolant gas groove sets. Each of the distinct coolant gas groove sets has one or more coolant gas supply holes and corresponds to a respective one of the coolant gas groove opening sets.

Abstract: A device for generating a sampling strobe, which controls a sampling device to sample an input signal, includes a phase shifter configured to phase shift an input clock to provide multiple phase shifted input clock signals; and aperture generating circuits configured to generate sampling clock signals from the phase shifted input clock signals, respectively, by adjusting duty cycles of the phase shifted input clock signals to provide sampling pulses having desired pulse widths, where for each sampling clock signal of the sampling clock signals, a rising edge and a falling edge of each sampling pulse originate from the same input edge of the input clock; and apply the sampling clock signals to interleaved samplers of the sampling device, respectively, for controlling sampling of the input signal by integrating according to the desired pulse widths of the sampling pulses, where the desired pulse widths correspond to sampling apertures.

Abstract: A method for painting a body of a vehicle with a multi-tone paint scheme. The method includes: applying a first paint of a first color to the body; oven-curing the first paint; applying a second paint of a second color to the body, the second paint configured to be cured by ultraviolet light, the second color is different from the first color, and curing the second paint by exposing the second paint to ultraviolet light.

Abstract: The technology relates to methods for detecting and classifying emotions in textual communication, and using this information to suggest graphical indicia such as emoji, stickers or GIFs to a user. Two main types of models are fully supervised models and few-shot models. In addition to fully supervised and few-shot models, other types of models focusing on the back-end (server) side or client (on-device) side may also be employed. Server-side models are larger-scale models that can enable higher degrees of accuracy, such as for use cases where models can be hosted on cloud servers where computational and storage resources are relatively abundant. On-device models are smaller-scale models, which enable use on resource-constrained devices such as mobile phones, smart watches or other wearables (e.g., head mounted displays), in-home devices, embedded devices, etc.

Abstract: A layer of a plate-fin heat exchanger includes: an inlet side for receiving a fluid; an outlet side; a plurality of first fins each having a first end located at the inlet side and extending in a direction toward the outlet side to a second end to provide a plurality of first flow channels for the fluid; a plurality of second fins each having a first end adjacent to the second end of the plurality of first fins and extending from the second end of the plurality of first fins toward the outlet side to a second end to provide a plurality of second flow channels for the fluid; and a cavity provided in each of the plurality of first fins and/or each of the plurality of second fins at a boundary between the plurality of first fins and the plurality of second fins.

Abstract: A manufacturing system includes: stability targets; a set of rails; robots including photogrammetry targets mounted on heads of the robots, the robots move along the set of rails, and each of the robots including a plasma cutting tool or a camera mounted on one of the heads; and a photogrammetry system. The photogrammetry system includes: a support stand; overhead cameras mounted on the support stand above the robots and a workpiece to be worked on by one of the robots; and a control module. The control module: via the overhead cameras, determines locations of the stability targets and photogrammetry targets; based on the locations of the stability targets and photogrammetry targets, determines locations of the overhead cameras and heads of the robots; and controls the robots to create and inspect a feature on the workpiece based on the locations of the overhead cameras and heads of the robots.

Abstract: Methods and formulations for treating oncological disorders in humans using Coenzyme Q10 are described.