Abstract: A disposable absorbent article having a topsheet, a backsheet, an absorbent core structure disposed between the topsheet and backsheet, and a flex bond channel region. The absorbent core structure includes an upper nonwoven layer having polymer fibers, a lower nonwoven layer having polymer fibers, and an inner core layer disposed between the upper and lower nonwoven layers. The flex bond channel region has a dry channel depth of from about 1.0 mm to about 4.5 mm and a channel width of from about 1.0 mm to about 3.0 mm. The flex bond channel region has a Dry MD Bending Resistance of less than about 0.04 N/mm. The inner core layer comprises an outer absorbent zone that substantially surrounds a central absorbent zone. The basis weight of the central absorbent zone is greater than the basis weight of the outer absorbent zone.

Abstract: A disposable absorbent article having a topsheet, a backsheet, and an absorbent core structure disposed therebetween. The absorbent core structure includes an upper nonwoven layer comprising polymer fibers, a lower nonwoven layer comprising polymer fibers, and an inner core layer comprising cellulosic fibers and superabsorbent particles disposed therebetween. The inner core layer is profiled in the longitudinal and lateral directions and is defined by a central absorbent zone and an outer absorbent zone substantially surrounding the central absorbent zone. The basis weight of the central absorbent zone is greater than the basis weight of the outer absorbent zone. A plurality of cellulosic fibers of the inner core layer penetrate through the lower surface of the upper nonwoven layer. The upper nonwoven layer has a Circular Bend of from about 2.5 gf to about 10 gf as measured according to the Circular Bend Method.

Abstract: A disposable absorbent article having a topsheet, a backsheet, and an absorbent core structure disposed therebetween. The absorbent core structure includes an upper nonwoven layer comprising polymer fibers, a lower nonwoven layer comprising polymer fibers, and an inner core layer comprising cellulosic fibers and superabsorbent particles disposed therebetween. The inner core layer is profiled in the longitudinal and lateral directions and is defined by a central absorbent zone and an outer absorbent zone substantially surrounding the central absorbent zone. The basis weight of the central absorbent zone is greater than the basis weight of the outer absorbent zone. The absorbent article has a first average density measured in the central absorbent zone and a second average density measured in the outer absorbent zone. The first and second average density are between about 0.045 g/cm3 and about 0.150 g/cm3, and the second density is within about 0 to about 20% of first density.

Abstract: A disposable absorbent article having a topsheet, a backsheet, and an absorbent core structure disposed therebetween. The absorbent core structure includes an upper nonwoven layer comprising polymer fibers, a lower nonwoven layer comprising polymer fibers, and an inner core layer comprising cellulosic fibers and superabsorbent particles disposed therebetween. The inner core layer is profiled in the longitudinal and lateral directions and is defined by a central absorbent zone and an outer absorbent zone substantially surrounding the central absorbent zone. The central absorbent zone comprises a pair of inwardly concave longitudinal side edges, an outwardly convex front edge, and an outwardly convex rear edge. The basis weight of the central absorbent zone is greater than the basis weight of the outer absorbent zone. The absorbent article has an average density in the outer absorbent zone that is within about 0 to about 20% of the average density in the central absorbent zone.

Abstract: A fluid coolant system for a gantry of a medical imaging apparatus cools scalable detector electronic assemblies (DEAs) within the gantry. Each DEA includes therein a first chill plate for cooling detector elements and a second chill plate for cooling electronic components and power supplies. Coolant flow cascades sequentially through the first chill plate and then through the second chill plate. Plural DEAs in an interconnected chain cascade coolant in sequence through all their first chill plates, before cascading the coolant through all their second chill plates. A matrix of the scalable DEAs are circumferentially and axially oriented within the imaging system's gantry, for any axial length scanning field of the imaging apparatus.

Abstract: Disclosed herein is glass-ceramic and glass-ceramic articles including a crystalline phase comprising a jeffbenite crystalline structure, glass that may be cerammed to become such, and methods of making and using the same.

Abstract: Disclosed herein are methods and systems of metadata management for reviewing data from microscopy experimental sessions. Image data from an experimental session is stored in an archive at one or more filepath locations, either locally or on a network. Metadata associated with the image data is stored in a database with a reference to the filepath where the raw image is stored, such that the metadata is associated in the database with the image data. A user can perform post-experimental filtering, sorting, and searching of the underlying image data using the metadata, which allows the image data to be analyzed without duplication of the image data and without manual review of each individual image. The filtered data is presented in an interactive timeline format.

Abstract: A system includes a robotic arm of a robotic device, an imaging device coupled to the robotic arm, and a processor configured to control movement of the robotic arm to move the imaging device along a preprogrammed measurement path of a transparency while prompting the imaging device to record images of localized portions of the transparency. The processor is configured to determine one or more localized transparency characteristics based on an analysis of the images of the localized portions.

Abstract: A machine for forming a container from a blank of sheet material includes a frame and an identification tag applicator mounted to the frame. The blank includes a first surface that forms an interior surface of the container and a second surface that forms an exterior surface of the container. The identification tag applicator is configured to apply an identification tag to the first surface of the blank. The machine also includes a mandrel assembly mounted to the frame and located operationally downstream from the identification tag applicator. The mandrel assembly includes a mandrel having an external shape complimentary to an internal shape of at least a portion of the container. The machine also includes a lift assembly configured to lift the blank having the identification tag adhered thereto towards the mandrel and wrap the blank about the mandrel.

Abstract: Disclosed herein are methods and systems for selectively managing different temporal and/or spatial resolution images and metadata collected during a transmission electron microscope (TEM) session. The system includes a transmission electron microscope and a computer system communicatively coupled to the transmission electron microscope. The computer system includes memory, data storage, and at least one processor configured for continuously receiving, from the transmission electron microscope, data captured at a lower temporal and/or spatial resolution and selectively receiving, from the transmission electron microscope, data captured at a higher temporal and/or spatial resolution.

Abstract: Systems and methods for neural synchronization via timed and controlled kinetic stimulation. The method involves stimulating a first limb located on one side of a median plane and transverse plane, while simultaneously stimulating a second limb located on the opposite side of the planes. Subsequently, a third and fourth limb are stimulated in alternating fashion, also located on opposing sides of the median and transverse planes. The method includes dynamically adjusting the synchronization of the stimulation pulses based on timing signals generated by a software-controlled algorithm. Additionally, synchronization is further calibrated by monitoring and recalculating neural activity distribution based on real-time patient data, ensuring precise coordination of stimulation pulses across all limbs.

Abstract: The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the LDHA gene, as well as methods of inhibiting expression of LDHA, methods of inhibiting LDHA and HAO1, and methods of treating subjects that would benefit from reduction in expression of LDHA, such as subjects having an oxalate pathway-associated disease, disorder, or condition, using such dsRNA compositions.

Abstract: Systems and methods for image generation are described. Embodiments of the present disclosure receive a text phrase that describes a target image to be generated; generate text features based on the text phrase; retrieve a search image based on the text phrase; and generate the target image using an image generation network based on the text features and the search image.

Abstract: Disclosed herein are glass-ceramic articles including a crystalline phase comprising a jeffbenite crystalline structure. The glass-ceramic articles may include a first surface, a second surface opposite the first surface, and a perimeter defining a shape of the glass-ceramic article. The glass-ceramic articles may further include a phase assemblage comprising one or more crystalline phases and a glass phase. The one or more crystalline phases may include a crystalline phase having the jeffbenite crystalline structure.

Abstract: The concepts and technologies disclosed herein are directed to time-aware blockchain staged regulatory control of Internet of Things (“IoT”) data. A federation platform can receive a registration request from an enterprise edge platform to register a blockchain identifier for publication of public data on a public blockchain. The federation platform can determine if the registration request contains any restricted data parameters. In response to determining that the registration request does not contain any restricted data parameters, the federation platform can query a security module to obtain an encryption key. The federation platform can receive the encryption key from the security module. The federation platform can store the encryption key in association with the blockchain identifier and an enterprise edge platform ID that uniquely identifies the enterprise edge platform.

Abstract: Methods for treating a neuropsychiatric disorder by administering an iboga alkaloid and a cardioprotective agent in conjunction with analysis of brain image data is described. Also described are methods to improve brain health and to slow or reverse brain aging by disorder by administering an iboga alkaloid and a cardioprotective agent, where analysis of brain image data is used to monitor and/or evaluate treatment effectiveness.

Abstract: Digital content layout encoding techniques for search are described. In these techniques, a layout representation is generated (using machine learning automatically and without user intervention) that describes a layout of elements included within the digital content. In an implementation, the layout representation includes a description of both spatial and structural aspects of the elements in relation to each other. To do so, a two-pathway pipeline that is configured to model layout from both spatial and structural aspects using a spatial pathway, and a structural pathway, respectively. In one example, this is also performed through use of multi-level encoding and fusion to generate a layout representation.

Abstract: Disclosed embodiments relate to apparatuses and methods for wound treatment. In certain embodiments, a negative pressure wound therapy apparatus includes one or more electronic components configured to be incorporated into layers of the wound dressing or integrated on top of the wound dressing. In some embodiments, a negative pressure source is incorporated into the wound dressing. The negative pressure source can be sealed between two moisture vapor permeable cover layers or enclosed in a moisture vapor permeable pouch, and may be received in a recess of an absorbent layer or spacer layer of a wound dressing apparatus.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for securely publishing and accessing a media's premium content. Methods include a media that comprises premium content encrypted with a first cryptographic key. The media also comprises data structures that include this key and the access entitlements. These data structures are encrypted using the key for each entity that can authorize user access to the media. Methods further include verifying user access to the media and then providing the decrypted premium content. Methods include decrypting the data structure using the authorizing entity's key and providing the first cryptographic key in the decrypted data structure to the client device, after verifying that the user has the appropriate access entitlements for the media. Methods include decrypting the premium content using the first cryptographic key and then displaying the media, including the decrypted premium content, on the client device.

Abstract: A glass composition includes greater than or equal to 45 mol % to less than or equal to 60 mol % SiO2; greater than or equal to 15 mol % to less than or equal to 25 mol % Al2O3; greater than or equal to 10 mol % to less than or equal to 20 mol % Li2O; greater than or equal to 0 mol % to less than or equal to 7.5 mol % Na2O; greater than or equal to 0 mol % to less than or equal to 5 mol % K2O; greater than or equal to 7 mol % to less than or equal to 13 mol % P2O5, and greater than or equal to 0 mol % to less than or equal to 4 mol % TiO2. The glass composition may have a liquidus temperature of less than or equal to 1300° C. and an inter-diffusion coefficient greater than or equal to 4000 ?m2/hour. The glass composition is chemically strengthenable. The glass composition may be used in a glass-based article or a consumer electronic product.