Abstract: An electronic data interface overlay for modifying existing formulary data is provided along with systems and methods for the same. The overlay comprises member-specific clinical data and causes automatic generation of code(s) indicating coverage denial upon querying of treatments of the existing formulary data associated with certain of the member-specific clinical data, such as pharmacogenetic (“PGx”) test results, of the data interface overlay. The formulary data includes alternative treatments which may be suggested and approved upon denial based on PGx test results. An electronic health record is automatically updated with the alternative treatment.

Abstract: Systems and methods for pin lift detection compensation in Low Dropout (LDO) regulators. In an illustrative, non-limiting embodiment, a System-On-Chip (SoC) may include: a circuit; and an LDO regulator coupled to the circuit, where the LDO includes a transistor having a first terminal coupled to a first voltage rail and a second terminal coupled to the circuit, where the second terminal is configured to receive a probe current produced from a second voltage rail, and where the first voltage rail is coupled to a compensating current source configured to draw a compensating charge equal to or greater than a charge imparted upon the second terminal by the probe current.

Abstract: A temperature correction circuit for a voltage reference circuit includes two amplifiers, each having an output that controls a respective transistor that produces correction current for adjusting the reference voltage. Both amplifiers include one input coupled in a path to a reference voltage source and another input coupled in a path to a temperature sensing diode circuit. One amplifier's output controls the conductivity of its respective transistor to adjust the reference voltage when the temperature exceeds a high temperature set point. The other amplifier's output controls the conductivity of its respective transistor to adjust the reference voltage when the temperature falls below a low temperature set point.

Abstract: Aspects of this disclosure are directed to controllers for, and methods of controlling, a hybrid multiphase DC-DC converter comprising a plurality of switched-inductor current paths, such methods comprising: comparing an output voltage with an output-reference voltage; in response to a difference between the output voltage and the output-reference voltage, adjusting a respective current control parameter of each current path; comparing a first voltage across a first flying capacitor with a first capacitor-reference voltage; and in response to a difference between the first voltage across the first flying capacitor and the first capacitor-reference voltage, modifying the respective current control parameter of a one of the current paths.

Abstract: Embodiments of a power management unit for a device, a power management unit for a biomedical patch, and a biomedical patch are disclosed. In an embodiment, a power management unit for a batteryless device includes a Thermoelectric Energy Generator (TEG) harvester, a Near Field Communication (NFC) harvester, a Direct Current (DC)-DC converter coupled between the TEG harvester and the NFC harvester, a first switch and a second switch coupled between the DC-DC converter and the NFC harvester, a central control unit (CCU) coupled between the first switch and the second switch and configured to control the DC-DC converter, and a capacitor coupled between the CCU, the first and second switches, and a load. Other embodiments are also disclosed.

Abstract: System and methods for alerting a healthcare provider to prescribed treatments having reduced or no effectiveness due to genetic composition is provided. A database containing treatments known to have reduced or no efficacy in persons having particular genetic markers is queried to determine whether any treatments prescribed by, or likely to be prescribed by, a healthcare provider to the patient are known to have reduced or no efficacy in persons having the same certain genetic markers as the patient. An alert indicating such information is displayed at a healthcare provider system.

Abstract: A method, power converter and controller are disclosed for controlling a power converter having a main converter connected between a first input voltage and a ground and having a main output at an output terminal, an auxiliary converter connected between a second input voltage and the ground and having an auxiliary output, an output capacitor connected between the main output terminal and a ground, and an auxiliary capacitor connected between the auxiliary output and the main output terminal; and a controller; the method comprising: operating the main converter at a first frequency, operating the auxiliary converter at a second frequency; controlling the main converter to control the voltage at the auxiliary output; and controlling the auxiliary converter to control the voltage at the main output.

Abstract: Disclosed are a controller and power converter having a main buck converter connected between a first input voltage and ground and having a main output, a bidirectional auxiliary converter connected between a second terminal and ground and having an auxiliary output connected to the main output, an output capacitor, and an auxiliary capacitor connected between the second terminal and the ground for providing a second terminal voltage at the second terminal; the controller comprising: first control circuit configured to operate the main converter at a first frequency; and second control circuit configured to operate the auxiliary converter at a higher frequency; the first control circuit being further configured to operate the main converter in dependence on the second terminal voltage; and the second control circuit being further configured to operate the auxiliary converter to control the voltage at the main output terminal.

Abstract: System and methods for providing interoperable, automated, real-time genetic efficacy contraindication checks are provided. Coverage requests involving for medications for patients from nodes of an electronic network. A testing results query is made for each request at database(s) with identifying information for the patients to determine if genetic efficacy testing results are available. If so, a testing results query is performed to determine if any of the medications in a respective coverage request are contraindicated for a respective patient based on the genetic efficacy testing results. And, if so, a standardized, encoded message is returned to the originating node for the respective coverage request query indicating each contraindicated medication.

Abstract: System and methods for automating preauthorization of genetic efficacy testing with prescription dispensation are provided. Coverage requests for medicines are received from pharmacy systems. Databases are queried to retrieve policy rules for the coverage requests. A coverage decision analysis is performed and where an associated medication is otherwise approved for coverage and where genetic efficacy testing is available for the associated medication, a prior authorization for such genetic efficacy testing is automatically generated and included with which is transmitted together with an approval of coverage decision to a requesting one of said number of pharmacy systems.

Abstract: Oscillator circuitry and methods of operation thereof are provided in which the oscillator circuitry includes at least a first oscillator, a second oscillator, and a lock detector. The first oscillator is configured to generate a first clock signal. The second oscillator is configured to generate a second clock signal. The lock detector is configured to detect a stable phase lock between the first clock signal and the second clock signal and to switch an output of the oscillator circuitry from the first clock signal to the second clock signal in response to detecting the stable phase lock.

Abstract: The present invention relates to a circuit comprising a self-conducting transistor referred to as power transistor, a further transistor referred to as control transistor, a further transistor referred to as first protection transistor, and a string referred to as a Zener string, which comprises at least one Zener diode, wherein the power transistor is coupled between a first terminal of the circuit and a first node of the circuit, wherein the control transistor is coupled between the first node and a second terminal of the circuit, wherein a gate terminal of the control transistor is coupled to a third terminal of the circuit, wherein the first protection transistor is coupled between the first node and the second terminal, and wherein the Zener string is coupled between the first terminal and a gate terminal of the first protection transistor.

Abstract: A self-biased, closed loop, low current free running oscillator clock generator method and apparatus are provided with a current mode comparator connected to a trimming resistor and configured to compare an internally generated voltage reference VREF signal to a voltage feedback signal VFB, where the current mode comparator comprises a common gate amplifier connected to a current mirror circuit in a negative self-biased closed loop to generate a control current signal for controlling a current controlled oscillator to produce an output clock signal having a clock frequency based on the control current signal, where a frequency-to-voltage converter is connected in a feedback path to receive the output clock signal and is configured to produce the voltage feedback signal VFB for input to the current mode comparator, wherein the clock frequency of the output clock signal is tuned to a nominal locked output frequency fOUT by the trimming resistor.

Abstract: Oscillator circuitry and methods of operation thereof are provided in which the oscillator circuitry includes at least a first oscillator, a second oscillator, and a lock detector. The first oscillator is configured to generate a first clock signal. The second oscillator is configured to generate a second clock signal. The lock detector is configured to detect a stable phase lock between the first clock signal and the second clock signal and to switch an output of the oscillator circuitry from the first clock signal to the second clock signal in response to detecting the stable phase lock.

Abstract: Embodiments of a power stage for a direct current (DC)-DC converter and a DC-DC converter are disclosed. In an embodiment, a power stage for a DC-DC converter includes an input terminal from which input power of the DC-DC converter with an input DC voltage is received, a high-side segment connected between the input DC voltage and an output signal of the power stage, and a low-side segment connected between the output signal of the power stage and ground. At least one of the high-side segment and the low-side segment includes stacked transistors having isolation terminals that are biased to reduce substrate injection.

Abstract: System and methods for suggesting insurance eligible genetic tests to a healthcare provider are disclosed. An EMR system is queried to retrieve insurance information, active medications, and diagnoses associated with a particular patient. An eligibility database is queried to retrieve insurance eligibly rules for a particular policy of a particular insurance providers based on the retrieved insurance information. A laboratory information system (“LIS”) applies the retrieved insurance eligibility rules to the retrieved active medications and diagnoses to determine eligible genetic tests. An electronic notification comprising an order form for each of the eligible genetic tests is transmitted from the LIS to the EMR.

Abstract: A semiconductor device has first and second current terminals and a control terminal that can be biased to form an electrically conductive path from the first current terminal to the second current terminal through a channel region is provided with a temperature-sensitive current limiting device. The current-limiting device is integrally formed from semiconductor material of the control terminal and is configured to cause a reduction in electrical current flowing through the channel region when the temperature of the device in the channel region exceeds a predetermined threshold temperature.

Abstract: Embodiments of a multi-mode transition circuit for a DC-DC converter and a DC-DC converter are disclosed. In an embodiment, a multi-mode transition circuit for a DC-DC converter includes a transconductance amplifier operably connected to a first resistor-capacitor (RC) network and switches, a comparator operably connected to a second RC network, where the first and second RC networks are operably connected to a reference voltage, a multiplexer operably connected to the transconductance amplifier and the comparator, and an operation mode selector configured to enable or disable the transconductance amplifier and turn on or off the switches in a sequence when transitioning between a pulse-frequency modulation (PFM) mode and a pulse-width modulation (PWM) mode.

Abstract: A semiconductor device has first and second current terminals and a control terminal that can be biased to form an electrically conductive path from the first current terminal to the second current terminal through a channel region is provided with a temperature-sensitive current limiting device. The current-limiting device is integrally formed from semiconductor material of the control terminal and is configured to cause a reduction in electrical current flowing through the channel region when the temperature of the device in the channel region exceeds a predetermined threshold temperature.

Abstract: System and methods for alerting a healthcare provider to prescribed treatments having reduced or no effectiveness due to genetic composition is provided. A database containing treatments known to have reduced or no efficacy in persons having particular genetic markers is queried to determine whether any treatments prescribed by, or likely to be prescribed by, a healthcare provider to the patient are known to have reduced or no efficacy in persons having the same certain genetic markers as the patient. An alert indicating such information is displayed at a healthcare provider system.