Abstract: The present invention relates to certain indole derivatives that are modulators of PPAR?, to processes for their preparation, to pharmaceutical compositions containing them and to their use in medicine.

Abstract: A device for blending materials and a bag for use in such devices. The device has at least one paddle for acting on a sample and a carrier against which a sample may be crushed by the paddle. The device is arranged to allow adjustment of the spacing between the paddle and carrier during operation. The bag is suitable for use in such a device but can be used in other devices.

Abstract: An exhaust system for a use with an engine is provided. The exhaust system may have an exhaust manifold configured to direct exhaust from the engine, and a main turbocharger connected to receive exhaust from the exhaust manifold. The exhaust system may also have a recirculation turbocharger having a compressor connected to receive exhaust from the exhaust manifold in parallel with the main turbocharger, and a turbine connected to receive exhaust from the main turbocharger to drive the compressor. The exhaust system may further have a control valve located downstream of the recirculation turbocharger to regulate exhaust flow through the compressor.

Abstract: An apparatus and method for optimizing reaction for curable material is disclosed. In operating rooms that are relatively colder, heating curable material can increase the reaction time. A heater may be placed in thermal contact with the curable material to heat the curable material.

Abstract: An apparatus and method for transferring curable material to an injector to convenient deliver the curable material to a patient. The apparatus contains a mixing chamber for mixing a liquid component and a powder component to form a curable material. The curable material is transferred to an injector to when the mixing chamber and injector are moved toward each other.

Abstract: The present invention in several embodiments is a clip-on mirror accessory for laptop computers. The present invention in several embodiments is a rotatable mirror device that can be easily affixed to the screen of a laptop to easily view one's face and surroundings. This device can assist users in viewing the area behind their back while typing. This can be especially beneficial for users that may be working on confidential materials. The present invention can also assist users in checking their hair, makeup and teeth.

Abstract: An apparatus and associated method for constructing prefabricated foam panels is provided. While making a longitudinal pass over a foam block, the apparatus flattens the foam block, cuts longitudinal kerfs in the foam block, and draws metal studs into the kerfs. The apparatus comprises a unique, heated blade having a shape similar to the cross section of a metal stud. The blade kerfs foam blocks, including blocks made of recycled or low-grade foam. The associated method includes kerfing the foam blocks by passing the blade through the foam blocks and drawing metal studs into the kerfs.

Abstract: This invention relates to non-steroidal compounds that are modulators of androgen receptor, and also to the methods for the making and use of such compounds.

Abstract: This invention relates to non-steroidal compounds that are modulators of androgen receptor, and also to the methods for the making and use of such compounds.

Abstract: A camera link cable assembly transmits signals from a digital camera to a frame grabber. The cable assembly has a significantly longer length than that provided by camera link cables of the prior art. A signal conditioning device is an integral part of the cable. The signal conditioning device extends the maximum distance that a signal can be transmitted from the camera to a frame grabber from approximately 7 meters at 85 MHz of the prior art cables, to approximately 40 meters at 85 MHz.

Abstract: A portable, light-activated, mist sprayer system comprising direct current power supply, an ambient light sensor, electronic circuitry that evaluates an electrical signal received from the light sensor to determine whether a “dusk” or “dawn” light condition exists; a container of treating fluid at a desired concentration; a motor and pump that are activated at the appropriate time as determined by the sensed light condition; at least one sprayer nozzle that will dispense a mist containing the treating fluid whenever the pump is operating; and a timer that turns off the pump after a preset interval to terminate the spraying cycle. A preferred utility for the system of the invention is spraying dilute solutions of insecticide or insect repellent during the periods of significant insect activity that typically occur around dusk and dawn. An RF receiving unit is also disclosed for optional activation using a remote transmitter.

Abstract: Heterocycle substituted ketoamide derivatives of Formula (I), wherein the substitutes A, D, A and R are defined as in claim in, which are useful as cathepsin K inhibitors are described herein. The described invention also includes methods of making such heterocycle substituted ketoamide derivatives as well as method of using the same in the manufacture of medicaments for the treatment of disorders, including osteoporosis, associated with an imbalance between bone resorption and formation which can ultimately lead to fracture.

Abstract: This invention relates to non-steroidal compounds that are modulators of androgen receptor, and also to the methods for the making and use of such compounds.

Abstract: The invention provides a bioadhesive composition comprising a polysaccharide and an energy converter, wherein the energy converter is activated by non-UV light. The composition may be prepared by dissolving the polysaccharide and the energy converter in an aqueous acidic solution. The composition, in the form of a film or a gel, may be used for repairing a discontinuity in an area of tissue or for joining tissue.

Abstract: The present invention is a bacteria and nutrient delivery composition containing bran. The subject composition is preferably made in the form of a tablet that is structurally stable without being excessively hard. The tablets preferably have a configuration that reduces the likelihood of premature shearing in tableting presses or jamming in feeder devices for biomass generators. Methods of manufacturing the bacterial delivery composition in a structurally stable form that maintains bacterial viability are also provided.

Abstract: An apparatus and method for introducing material into an injection site of a patient is disclosed. The device includes a cannula and a carrier. The cannula is inserted into an injection site of a patient. The carrier is connected to an injector containing a volume of material. Material may be pre-loaded into the carrier so that the material is delivered to a distal end of the carrier from the injector and the carrier is thus pre-loaded with material. A portion of the distal end of the pre-loaded carrier is inserted into the cannula and material is delivered to an injection site. The supply section can be rotatable with respect to the longitudinal axis of the inner section.

Abstract: Compounds of formula (I): with a variety of therapeutic uses, more particularly novel prodrugs that are particularly useful for delivering a parent compound for selective estrogen receptor modulation.

Abstract: A method of restoring a discolored automobile headlight lens without removal of the lens from the automobile consistent with certain embodiments involves wet abrading an outer surface of the lens with successively finer grit wet sanding disks, using a low speed rotary or orbital tool having a flexible sanding holder holding the sanding disks, until a smooth surface is achieved exhibiting no discoloration, wherein the wet sanding disks comprise disks starting from approximately 220 to 400 grade down to approximately 2000 grade; polishing the outer surface of the lens with an aqueous paste abrasive polish containing aluminum oxide abrasive particles; cleaning any residue from the outer surface of the lens by wiping the lens with a lint free cloth; and spraying a film forming aqueous polymer dispersion containing an ultraviolet protectant to the outer surface of the lens, wherein the sealer comprises of acrylic urethane copolymers, Hindered Amine Light Stabilizers, benzotriazole UV light absorbers, 1-methyl-2-py