Abstract: Prosaposin, saposin C and various peptide fragments of saposin C stimulate neurite outgrowth in vitro. In addition, prosaposin and saposin C promote increased myelination ex vivo. Prosaposin is present in large neurons of the brain, including both upper and lower motor neurons.

Abstract: A note card is sized and shaped for repeated insertion into a shirt pocket. The preferably white card has lines for notes on a front side, and rounded corners to help the card slide into a pocket repeatedly with little resistance. The card is of a certain selected thickness and stiffness, for a ceratin "feel" and to help it slide into the pocket without buckling. The front side of the card preferably has a "dull coat" surface finish selected to promote ease of writing, particularly with inks pens. The back surface of the card may be blank for obscuring it in shirt pocket, or it may have lines if used with a shirt of opaque material.