Abstract: A system for mixing or reconstituting a drug contained in a first container with a diluent or fluid contained in a second container. The second container has a port docking assembly for engaging the first container. The first container is rotatable and axially slidable within the port docking assembly. The port docking assembly has an actuator to urge a stopper fluidly sealing the first container into the interior of the first container. The port docking assembly further includes a movable plug constructed to fluidly seal the second container in a first, docked position and to provide access to the interior of the second container in a second, activated position, whereby fluid communication between the first and second containers is provided when the first and second containers are in the second, activated position.

Abstract: A system for mixing or reconstituting a drug contained in a first container with a diluent or fluid contained in a second container. The second container has a port docking assembly for engaging the first container. The first container is rotatable and axially slidable within the port docking assembly. The port docking assembly has an actuator to urge a stopper fluidly sealing the first container into the interior of the first container. The port docking assembly further includes a movable plug constructed to fluidly seal the second container in a first, docked position and to provide access to the interior of the second container in a second, activated position, whereby fluid communication between the first and second containers is provided when the first and second containers are in the second, activated position.

Abstract: A system for mixing or reconstituting a drug contained in a first container with a diluent or fluid contained in a second container. The second container has a port docking assembly for engaging the first container. The first container is rotatable and axially slidable within the port docking assembly. The port docking assembly has an actuator to urge a stopper fluidly sealing the first container into the interior of the first container. The port docking assembly further includes a movable plug constructed to fluidly seal the second container in a first, docked position and to provide access to the interior of the second container in a second, activated position, whereby fluid communication between the first and second containers is provided when the first and second containers are in the second, activated position.

Abstract: A system for mixing or reconstituting a drug contained in a first container with a diluent or fluid contained in a second container. The second container has a port docking assembly for engaging the first container. The first container is rotatable and axially slidable within the port docking assembly. The port docking assembly has an actuator to urge a stopper fluidly sealing the first container into the interior of the first container. The port docking assembly further includes a movable plug constructed to fluidly seal the second container in a first, docked position and to provide access to the interior of the second container in a second, activated position, whereby fluid communication between the first and second containers is provided when the first and second containers are in the second, activated position.

Abstract: A medical pump includes a chassis having a fixed seat, and a main carriage having a carriage footing for receiving a fluid delivery device and restricting its movement. An actuator automatically moves the main carriage between open and closed positions to engage the fluid delivery device to the seat. The seat establishes the position of both the main carriage and fluid delivery device in the closed position. The actuator is connected to the main carriage by a rear carriage assembly having a manual release element for disengaging the actuator from rear carriage assembly and thereby from the main carriage. A processing unit detects jam conditions by processing carriage position data and electrical load data from the actuator.

Abstract: A method and system for handling hazardous materials contained in a vial includes an isolation enclosure having an opening selectively sealable about the vial, a bag body portion, and a cap portion. A latching extraction element is attached to the cap portion and has a preceding engaging member to secure the vial to the isolation enclosure, an extraction member to be inserted into the vial and remove material therefrom, and a primary engaging member to secure the vial to the extraction member. A valve is mounted outside the isolation enclosure and controls the flow of fluid from the vial. An adaptor having a reseal member permits flow when coupled to the valve and restricts flow when uncoupled from the valve. Once uncoupled, the adaptor is removably associated with a second valve located remotely from the isolation enclosure, allowing fluid to pass into the second valve.

Abstract: A container for holding a concentrated drug for a mixing system includes a barrel with a cover structure including a delivery passage at a first end and a closing structure at an opposite, second end. A female Luer lock fitting defines the delivery passage at the first end. The closing structure and the female Luer lock fitting can each be formed integrally with the barrel, or the closing structure can be a slidable stopper. The closing structure may also include a holder. The holder is constructed to move between two positions. In the first position, the holder is in a elevated position on the second end of the barrel. The barrel can vent vapor around the cover piece. In the second position, the holder is depressed onto the barrel and it cannot vent vapor. The cover structure may include a snap-on cover piece to fit over the first end. The cover piece includes the female luer lock fitting. The cover piece functions similar to the holder.

Abstract: A method and apparatus are provided for controlling the dispensing of a primary liquid from a pressurized source of primary liquid. Primary liquid is admitted through an inlet valve to a primary chamber having a primary element which is biased toward an initial position but is movable away from the initial position when subjected to the source pressure of the primary liquid. A sensor determines when the primary element has moved away from an initial position to a predetermined final position, and the inlet valve is closed in response thereto. The difference between the initial and final positions defines a predetermined dispensing volume. An outlet valve is opened to dispense the dispensing volume under the biasing force of the primary element which returns to the initial position. A sensor determines when the primary element has returned to the initial position, and the outlet valve is closed in response thereto.

Abstract: The present invention is directed to a syringe plunger for use to administer a solution front a syringe of the type having an axially slidable piston sealing an axially extending barrel having a nozzle. The plunger includes a rigid stem member axially extending from a distal end to a proximal end. The plunger also includes threads or other attaching mechanism at the proximal end of the stem for removable attachment to the slidable piston. The stem member includes a first surface at the distal end of the stem for application of axial force to the stem so as to move the slidable piston in the barrel. Advantageously according to the invention, the stem also includes a second surface at an axially intermediate position on the stem for alternative application of axial force to the stem so as to initially move the slidable piston in the barrel, which is especially convenient for syringe users with small hands.

Abstract: An apparatus and method are disclosed for compounding of parenteral admixture solutions, and recirculation with the admixture solution being formed. The apparatus includes a multiple pump cassette configured for operative association with a pump driver, whereby one or more selected source solutions are delivered through a pump cassette to an associated admixture container. After pumping of each source solution, the present method contemplates that the admixture being formed is recirculated through the pump cassettes thereby diluting any source solution in the cassettes and associated tubing. In this manner, the possible mixture of incompatible source solutions, resulting in formation of precipitate, is desirably avoided.

Abstract: A drug storage and delivery system that includes a drug containing vial assembly, a syringe assembly, and an adapter assembly for attaching the vial assembly to the adapter assembly. The vial assembly includes a vial that is provided with a pierceable stopper and a skirt member that circumscribes the outside of the vial. The syringe assembly includes a cannula extending longitudinally therethrough. The adapter assembly attaches the vial assembly to the syringe assembly in a manner that permits communication between the interior of the vial and the cannula extending through the syringe. The system also permits attachment of the syringe assembly to a container filled with a diluent and means for delivering the diluent into the vial assembly and subsequently directing the mixed solution back into the container.

Abstract: Container systems employing a diluent container having an extractor that is helically threaded and is used to engage a resilient undercut vial stopper of an additive container.

Abstract: A thin flexible fluid-tight cover of PVC is bonded to a rigid port of a diluent container which is to be subjected to heat sterilization. The cover includes an outer flange for bonding to a complementary surface around the port, and a removable section for spanning the port. The removable section includes a central flexible diaphragm portion and a cylindrical wall portion. The diaphragm portion has at least one annular convolution whereby the diaphragm section is axially expandable by flexing of the convolution. A tear line is provided in a frangible section which joins the cylindrical wall portion to the outer flange. The cylindrical wall portion of the cover is disposed adjacent the outer surfaces of an abutment wall on the port to provide stress relief against rupture of the tear line from stresses generated in the cover during sterilization. A narrow post element is located adjacent the wall portion for concentrating manual pulling forces from an attached pull ring to a limited segment of the tear line.