Patents by Inventor John Saunders

John Saunders has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5856625
    Abstract: Articles produced by a powder metallurgy process involving forming of a shape by compaction followed by sintering without the application of external pressure from a stainless steel alloy powder produced by rapid atomization followed by an annealing treatment, which powder consists essentially of in weight percent, chromium 14-30, molybdenum 1 to 5, vanadium 0 to 5, tungsten 0 to 6, silicon 0 to 1.
    Type: Grant
    Filed: December 4, 1997
    Date of Patent: January 5, 1999
    Assignee: Powdrex Limited
    Inventors: John Saunders, Paul Dudfield Nurthen, Nigel Craig Trilk, Peter Ronald Brewin, John Vivian Wood
  • Patent number: 5808236
    Abstract: An apparatus and method therefore mount an array of different heatsinks to a closely packed array of data processing elements utilized within a data processing system. The apparatus includes a metal frame with multiple apertures in the bottom to allow access to the tops of the devices for which heatsinks will be provided. The metal frame has multiple apertures that allow access to the tops of the data processing elements underneath. The metal frame serves as a containment vehicle for multiple heatsinks, and also provides rigidity to the printed circuit board in the particularly vulnerable vicinity of the corners where the devices are attached to the printed circuit board.
    Type: Grant
    Filed: April 10, 1997
    Date of Patent: September 15, 1998
    Assignee: International Business Machines Corporation
    Inventors: Johnny Roy Brezina, John Saunders Corbin, Jr., Howard Victor Mahaney, Jr., James Robert Taylor
  • Patent number: 5747291
    Abstract: Bifunctional urokinase variants possessing improved fibrinolytic properties and thrombin inhibitory activities, plasmids used in the production of these polypeptides, as well as thrombolytic agents containing one of the bifunctional urokinase variants as active ingredient are described.
    Type: Grant
    Filed: September 27, 1996
    Date of Patent: May 5, 1998
    Assignee: Gruenenthal GmbH
    Inventors: Gerd J. Steffens, Stephan Wnendt, Johannes Schneider, Regina Heinzel-Wieland, Derek John Saunders
  • Patent number: 5738531
    Abstract: A self-aligning low profile socket for connecting a ball grid array type device through a dendritic interposer to a printed circuit board, the socket providing resources for attaching a heat sink to the electronic device with minimum thermal impedance. Compressive forces are evenly distributed over the pattern of the interposer array, and thermal conductivity is provided between the top of the electronic device and a heat sink, through the use of complementary concave and convex surfaces engaged by a flat screw mechanism. The socket exhibits a low profile while providing the flexibility of a dendritic interposer and effective heat sink attachment.
    Type: Grant
    Filed: September 9, 1996
    Date of Patent: April 14, 1998
    Assignee: International Business Machines Corporation
    Inventors: Daniel Paul Beaman, John Saunders Corbin, Jr., Danny Edward Massey
  • Patent number: 5713690
    Abstract: A method and apparatus for attaching heatsinks having a disproportional size relative to the electronic component to which they are attached. In general, the apparatus comprises variable-length attaching means for attaching each corner of the heatsink to the circuit card while maintaining sufficient contact with the electronic component. The variable-length attaching means includes a post and a receiving well. Both the post and receiving well include attaching means, such as threads and nuts, for attachment to the heatsink and circuit board, respectively. The variable-length attaching means accommodates height variations between parts, establishes high structural integrity after assembly, controls static and dynamic loading of the solder columns, allows for module re-work while re-using the heatsink and card, and provides adequate protection from shock, vibration, and handling.
    Type: Grant
    Filed: May 28, 1996
    Date of Patent: February 3, 1998
    Assignee: International Business Machines Corporation
    Inventors: John Saunders Corbin, Jr., Ciro Neal Ramirez
  • Patent number: 5686463
    Abstract: A class of novel oxadiazoles, substituted on one of the ring carbon atoms with a non-aromatic azacyclic or azabicyclic ring, and substituted on the other ring carbon atom with a substituent of low lipophilicity; are potent muscarinic agonists, and have good CNS penetrability. The compounds are therefore useful in the treatment of neurological and mental illnesses.
    Type: Grant
    Filed: March 19, 1987
    Date of Patent: November 11, 1997
    Assignee: Merck, Sharp & Dohme, Ltd.
    Inventors: Raymond Baker, Kevin John Merchant, Angus Murray MacLeod, John Saunders
  • Patent number: 5681721
    Abstract: Bifunctional urokinase variants possessing improved fibrinolytic properties and thrombin inhibitory activities, plasmids used in the production of these polypeptides, as well as thrombolytic agents containing one of the bifunctional urokinase variants as active ingredient are described.
    Type: Grant
    Filed: July 20, 1993
    Date of Patent: October 28, 1997
    Assignee: Gruenenthal GmbH
    Inventors: Gerd J. Steffens, Stephan Wnendt, Johannes Schneider, Regina Heinzel-Wieland, Derek John Saunders
  • Patent number: 5675889
    Abstract: Two substrates are produced each with a planar, mirror-image matrix of metal contacts in a surface wiring layer. The substrates are positioned with the matrices in parallel confrontation which defines pairs of confronting contacts. A metal ball is positioned between each pair of contacts with a respective volume of joining material between the ball and each of the two respective contacts. The volumes of joining material are simultaneously melted to allow surface tension to align the substrates and to accurately center the balls between each respective pairs of contacts in a plane defines by the matrix of balls.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: October 14, 1997
    Assignee: International Business Machines Corporation
    Inventors: John Acocella, Donald Ray Banks, Joseph Angelo Benenati, Thomas Caulfield, John Saunders Corbin, Jr., Karl Grant Hoebener, David P. Watson
  • Patent number: 5656042
    Abstract: A pumpable slurry of shredded scrap solid carbonaceous plastic-containing material that contains associated inorganic matter in admixture with a comminuted aluminosilicate-containing material having noncombustible constituents is reacted by partial oxidation to produce synthesis gas, reducing gas, or fuel gas. The noncombustible constituents in the aluminosilicate-containing material captures the inorganic matter in the scrap solid carbonaceous plastic-containing material while in the reducing atmosphere of the gasifier to produce nontoxic, nonleachable slag. The slurrying medium is water, liquid hydrocarbonaceous fuel, or mixtures thereof. Scrap plastics may be disposed of by the subject process without polluting the nation's environment.
    Type: Grant
    Filed: May 24, 1994
    Date of Patent: August 12, 1997
    Assignee: Texaco Inc.
    Inventors: Motasimur Rashid Khan, Christine Cornelia Albert, John Saunders Stevenson, George Neal Richter, David Charles Crikelair
  • Patent number: 5647876
    Abstract: A method is disclosed for recovering condensed solidified volatile metals from the slag that exits the reactor section of a partial oxidation reactor. In a partial oxidation reactor, condensed solidified volatile metals become adsorbed to the surface of the slag particles and other particulate matter associated with the gasification reaction, such as ash and soot. These particulate materials can be removed and recovered. Finely divided slag particles can be separated and contacted with a mineral acid to dissolve the adsorbed condensed volatile metals. An acid liquor results which contains dissolved volatile metal salts of the acid. The acid liquor containing the dissolved volatile metal acid salts is then electrolyzed to reduce the dissolved volatile metal acid salts to the corresponding elemental metal for recovery.
    Type: Grant
    Filed: September 26, 1995
    Date of Patent: July 15, 1997
    Assignee: Texaco Inc.
    Inventors: John Duckett Winter, John Saunders Stevenson, Jerrold Samuel Kassman, Harry Clarence Wiese, George Neal Richter, Lisa Marie Kocsis, Rinaldo Ibbarola Salvaleon
  • Patent number: 5405853
    Abstract: A class of novel thiadiazoles, substituted on one of the ring carbon atoms with a non-aromatic azacyclic or azabicyclic ring system, and substituted on the other ring carbon atom with a substituent of low lipophilicity, or a hydrocarbon substituent; are potent muscarinic agonists, and have good CNS penetrability. The compounds are therefore useful in the treatment of neurological and mental illnesses, and are also of benefit in the treatment of severe painful conditions.
    Type: Grant
    Filed: December 13, 1993
    Date of Patent: April 11, 1995
    Assignee: Merck Sharpe & Dohme Ltd.
    Inventors: Raymond Baker, Angus M. MacLeod, John Saunders, Kevin Merchant
  • Patent number: 5346906
    Abstract: Pyridines, substituted by a quinuclidine and a substituent of low lipophilicity or a hydrocarbon substituent, their salts and prodrugs, and formulations thereof are useful in the treatment of neurodegenerative disorders such as dementia. The compounds can be synthesized by methods analogous to these known in the art.
    Type: Grant
    Filed: November 16, 1992
    Date of Patent: September 13, 1994
    Assignee: Merck Sharpe & Dohme Ltd.
    Inventors: Raymond Baker, John Saunders, Timothy M. Willson, Janusz J. Kulagowski
  • Patent number: 5324723
    Abstract: 1,3-Oxazole and 1,3-thiazole compounds of formula I, and their pharmaceutically acceptable salts and prodrugs: ##STR1## wherein X represents oxygen or sulphur;R.sup.1 represents a non-aromatic azacyclic or azabicyclic ring system.
    Type: Grant
    Filed: July 1, 1993
    Date of Patent: June 28, 1994
    Assignee: Merck Sharpe & Dohme Ltd.
    Inventors: Raymond Baker, John Saunders, Roger J. Snow, Graham A. Showell
  • Patent number: 5260293
    Abstract: The present invention provides pyrazines, pyridazines or pyrimidines, or salts or prodrugs thereof, substituted on one of the ring carbon atoms thereof with a non-aromatic azacyclic or azabicyclic ring system; and independently substituted on each of the other ring carbon atoms with a substituent of low lipophilicity or a hydrocarbon substituent; which compounds stimulate central muscarinic acetylcholine receptors and therefore are useful in the treatment of neurological and mental illnesses.
    Type: Grant
    Filed: October 10, 1991
    Date of Patent: November 9, 1993
    Assignee: Merck Sharp & Dohme Limited
    Inventors: Raymond Baker, Leslie J. Street, John Saunders
  • Patent number: 5242927
    Abstract: A class of novel oxadiazoles, substituted on one of the ring carbon atoms with a non-aromatic azacyclic or azabicyclic ring and on the other ring carbon atom with a substituent which is convertible in vivo to an amino group, are potent muscarinic agonists, and exhibit improved CNS penetrability and duration of action compared with the corresponding amino compounds. The compounds are therefore useful in the treatment of neurological and mental illnesses.
    Type: Grant
    Filed: July 18, 1988
    Date of Patent: September 7, 1993
    Assignee: Merck Sharp & Dohme Limited
    Inventors: Raymond Baker, John Saunders, Angus M. MaCleod, Graham A. Showell
  • Patent number: 5140034
    Abstract: A class of 5-membered heterocyclic compounds having at least one heteroatom, substituted on the heterocyclic ring by an imidazolyl moiety, are useful in the treatment of psychotic disorders (e.g. schizophrenia and mania); anxiety; alcohol or drug withdrawal or dependence; pain; gastric stasis; gastric dysfunction (such as occurs with dyspepsia, peptic ulcer, reflux oesophagitis and flatulence); migraine, nausea and vomiting; movement disorders; and presenile and senile dementia.
    Type: Grant
    Filed: March 8, 1990
    Date of Patent: August 18, 1992
    Assignee: Merck Sharp & Dohme Ltd.
    Inventors: Raymond Baker, Christopher Swain, John Saunders
  • Patent number: 5073557
    Abstract: The compound (R)-3-[2-(6-chloropyrazin)yl]-1-azabicyclo[2.2.2]octane and its salts behave as M.sub.1, M.sub.3 muscarinic agonists and are useful in the treatment of neurological and mental disorders, preferably in a pharmaceutical formulation comprising the active compound in association with a pharmaceutically acceptable carrier. The compound can be prepared by via methods analogous to those known in the art and a chiral acid resolution.
    Type: Grant
    Filed: August 8, 1990
    Date of Patent: December 17, 1991
    Assignee: Merck Sharp & Dohme Limited
    Inventors: Raymond Baker, Leslie J. Street, John Saunders
  • Patent number: 5041456
    Abstract: The present invention provides a compound of formula I or a salt or prodrug thereof: ##STR1## wherein the dotted circle represents one or two double bonds in any position in the 5-membered ring;X, Y and Z independently represent oxygen, sulphur, nitrogen or carbon, provided that at least one of X, Y and Z represents oxygen, sulphur or nitrogen;A represents a group of formula II: ##STR2## in which: R.sup.1 represents hydrogen, hydroxy, C.sub.1-6 alkyl, C.sub.2-6 alkenyl, C.sub.2-6 alkynyl, C.sub.1-6 alkoxy, hydroxy(C.sub.1-6)alkyl, halogen, amino, cyano, --CONR.sup.6 R.sup.7 or --SO.sub.2 NR.sup.6 R.sup.7, in which R.sup.6 and R.sup.7 independently represent hydrogen, C.sub.1-6 alkyl, C.sub.2-6 alkenyl or C.sub.2-6 alkynyl;R.sup.2 represents hydrogen, halogen, C.sub.1-6 alkyl, C.sub.1-6 alkoxy or C.sub.1-6 alkylcarobnyl;V represents nitrogen, ##STR3## W represents oxygen, sulphur or ##STR4## in which R.sup.8 represents hydrogen, C.sub.1-6 alkyl, C.sub.2-6 alkenyl or C.sub.
    Type: Grant
    Filed: July 13, 1990
    Date of Patent: August 20, 1991
    Assignee: Merck Sharp & Dohme Ltd.
    Inventors: Raymond Baker, John Saunders, Christopher Swain
  • Patent number: 4992436
    Abstract: The present invention provides a spiro-azabicyclic compound or a salt or prodrug thereof, said compound comprising a saturated or unsaturated 5-membered heterocyclic ring containing two heteroatoms selected from oxygen, nitrogen and sulphur, no more than one of said heteroatoms being nitrogen; said heterocyclic ring having a spiro attachment to an optionally substituted azabicyclo[2.2.1]heptane or azabicyclo[3.2.1]octane ring system; which compounds are useful for the treatment of neurological and mental disorders.
    Type: Grant
    Filed: June 29, 1989
    Date of Patent: February 12, 1991
    Assignee: Merck Sharp & Dohme, Ltd.
    Inventors: Raymond Baker, Leslie J. Street, John Saunders
  • Patent number: 4952587
    Abstract: The present invention provides a compound of formula I or a salt or prodrug thereof: ##STR1## wherein the dotted circle represents one or two double bonds in any position in the 5-membered ring;X, Y and Z independently represent oxygen, sulphur, nitrogen or carbon, provided that at least one of X, Y and Z represents oxygen, sulphur or nitrogen;A represents a group of formula II: ##STR2## in which R.sup.1 represents hydrogen, hydroxy, C.sub.1-6 alkyl, C.sub.2-6 alkenyl, C.sub.2-6 alkynyl, C.sub.1-6 alkoxy, hydroxy(C.sub.1-6)alkyl, halogen, amino, cyano, --CONR.sup.6 R.sup.7 or --SO.sub.2 NR.sup.6 R.sup.7, in which R.sup.6 and R.sup.7 independently represent hydrogen, C.sub.1-6 alkyl, C.sub.2-6 alkenyl or C.sub.2-6 alkynyl;R.sup.2 represents hydrogen, halogen, C.sub.1-6 alkyl, C.sub.1-6 alkoxy or C.sub.1-6 alkylcarbonyl;V represents nitrogen, ##STR3## and W represents oxygen, sulphur or ##STR4## in which R.sup.8 represents hydrogen, C.sub.1-6 alkyl, C.sub.2-6 alkenyl or C.sub.
    Type: Grant
    Filed: February 3, 1989
    Date of Patent: August 28, 1990
    Assignee: Merck Sharp & Dohme Ltd.
    Inventors: Raymond Baker, John Saunders, Christopher Swain