Abstract: Compounds of Formula I: and their pharmaceutically acceptable salts are useful for the inhibition of HIV reverse transcriptase. The compounds may also be useful for the prophylaxis or treatment of infection by HIV and in the prophylaxis, delay in the onset or progression, and treatment of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antiviral agents, immunomodulators, antibiotics or vaccines.

Abstract: Compounds of Formula I and pharmaceutically acceptable salts and co-crystals thereof are useful for the inhibition of HIV reverse transcriptase. The compounds may also be useful for the prophylaxis or treatment of infection by HIV and in the prophylaxis, delay in the onset or progression, and treatment of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antiviral agents, immunomodulators, antibiotics or vaccines.

Abstract: Compounds of Formula (I): (Formula (I)) and their pharmaceutically acceptable salts are useful for the inhibition of HIV reverse transcriptase. The compounds may also be useful for the prophylaxis or treatment of infection by HIV and in the prophylaxis, delay in the onset or progression, and treatment of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antiviral agents, immunomodulators, antibiotics or vaccines.

Abstract: Compounds of Formula I: and their pharmaceutically acceptable salts are useful for the inhibition of HIV reverse transcriptase. The compounds may also be useful for the prophylaxis or treatment of infection by HIV and in the prophylaxis, delay in the onset or progression, and treatment of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antiviral agents, immunomodulators, antibiotics or vaccines.

Abstract: Compounds of Formula (I): (Formula (I)) and their pharmaceutically acceptable salts are useful for the inhibition of HIV reverse transcriptase. The compounds may also be useful for the prophylaxis or treatment of infection by HIV and in the prophylaxis, delay in the onset or progression, and treatment of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antiviral agents, immunomodulators, antibiotics or vaccines.

Abstract: Compounds of Formula I and pharmaceutically acceptable salts and co-crystals thereof are useful for the inhibition of HIV reverse transcriptase. The compounds may also be useful for the prophylaxis or treatment of infection by HIV and in the prophylaxis, delay in the onset or progression, and treatment of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antiviral agents, immunomodulators, antibiotics or vaccines.

Abstract: The present invention relates to Fused Tricyclic Heterocycle Derivatives of Formula (I), and pharmaceutically acceptable salts thereof, wherein R1-R8, A, X and n are as defined herein. The present invention also relates to compositions comprising at least one Fused Tricyclic Heterocycle Derivative, and methods of using the Fused Tricyclic Heterocycle Derivatives for treating or preventing HIV infection in a subject.

Abstract: The present invention relates to Fused Tricyclic Heterocycle Derivatives of Formula (I), and pharmaceutically acceptable salts thereof, wherein R1-R8, A, X and n are as defined herein. The present invention also relates to compositions comprising at least one Fused Tricyclic Heterocycle Derivative, and methods of using the Fused Tricyclic Heterocycle Derivatives for treating or preventing HIV infection in a subject.

Abstract: The present invention relates to Substituted Naphthyridinedione Derivatives and pharmaceutically acceptable salts thereof. The present invention also relates to compositions comprising at least one Substituted Naphthyridinedione Derivative, and methods of using the Substituted Naphthyridinedione Derivatives for treating or preventing HIV infection in a subject.

Abstract: The present invention relates to dihydropyrazole compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.

Abstract: The present invention is directed to amidopropoxyphenyl compounds which are antagonists of orexin receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which orexin receptors are involved.

Abstract: The present invention relates to dihydropyrazole compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.

Abstract: An axle driving apparatus having a housing having two members joined along a joint surface and a hydraulic axial piston pump and motor mounted on a center section located in the housing, wherein the pump and motor are mounted perpendicular to one another. The motor is engaged to a fixed thrust bearing located in the housing and the center section is located entirely between the joint surface and the thrust bearing.

Abstract: A control apparatus for a hydrostatic device such as a hydrostatic transmission having a rotatable pump and motor mounted in a housing, a moveable swash plate engaged to the pump and a trunnion shaft engaged to one side of the swash plate and extending out of the housing, wherein the control apparatus comprises a control arm and return arm mounted external to the transmission housing, the control arm engaging the trunnion shaft and having a ball bearing mounted thereon, so that the return arm engages the ball bearing to provide a return force to the control arm.

Abstract: A transmission mounted in a housing and including a hydrostatic pump and motor mounted on a center section, and a filter connected thereto to prevent contaminants from entering the hydrostatic system. A filter member is mounted to the center section and houses the filter.

Abstract: A transmission mounted in a housing and including a hydrostatic pump and motor mounted on a center section, having a motor shaft engaged to and driven by the hydraulic motor. An axle may also be mounted in the housing. The center section is secured to the housing using a plurality of bolts or other fasteners having a longitudinal axis parallel to the motor shaft and for the axle.

Abstract: A transmission mounted in a housing and including a hydrostatic pump and motor mounted on a center section, having a motor shaft engaged to and driven by the hydraulic motor. An axle may also be mounted in the housing. The center section is secured to the housing using a plurality of bolts or other fasteners having a longitudinal axis parallel to the motor shaft and for the axle.

Abstract: An axle assembly including a housing in which is mounted a transmission, axle shafts and a differential assembly including drive gears engaged to the axle shaft and at least one planet gear mounted on a shaft and engaged to the drive gears. The differential assembly includes a friction member on the shaft for engaging the planet gear.

Abstract: In a hydrostatic transmission or similar axle driving device, a bearing is used to support an axle in a separate axle chamber in the housing, and the bearing has an opening or lobe formed on the outer periphery thereof to allow fluid to flow from a chamber where the axle is housed and a separate chamber in the housing.

Abstract: An integrated hydrostatic transaxle including a housing in which is mounted a hydrostatic transmission having a hydraulic pump unit and a hydraulic motor unit with a motor shaft drivingly connected thereto. A differential assembly is drivingly linked to the motor shaft and is used to drive output axle shafts of the transaxle. The differential assembly includes a rotatable gear which is maintained in frictional engagement with at least one bearing surface for frictionally inhibiting the rotational movement thereof.