Abstract: A reverse-phase suspension polymerization process for the manufacture of polymer beads comprising forming aqueous monomer beads comprising an aqueous solution of water-soluble ethylenically unsaturated monomer or monomer blend and polymerizing the monomer or monomer blend, to form polymer beads while suspended in a non-aqueous liquid, and recovering polymer beads, in which the process comprises providing in a vessel (1) a volume (2) of non-aqueous liquid wherein the volume of non-aqueous liquid extends between at least one polymer bead discharge point (3) and at least one monomer feed point (4), feeding the aqueous monomer or monomer blend through orifices (5) into, or onto, the non-aqueous liquid to form aqueous monomer beads, allowing the aqueous monomer beads to flow towards the polymer bead discharge point initiating polymerization of the aqueous monomer beads to form polymerizing beads, wherein the polymerizing beads form polymer beads when they reach the polymer bead discharge point, removing a suspensi

Abstract: For controlling vehicle egress, an apparatus is disclosed. A system, method, and program product also perform the functions of the apparatus. The apparatus includes a vehicle, a processor, a memory that stores code executable by the processor. The processor determines whether a supervised passenger is in the vehicle, locks a vehicle door in response to a supervised passenger being in the vehicle, and unlocks the vehicle door in response to the vehicle satisfying one or more predetermined destination criteria. The one or more predetermined destination criteria may include reaching a predetermined location and/or detecting a guardian of the supervised passenger in proximity to the vehicle.

Abstract: The invention relates to novel compounds of the general formula (A-I), with Het-2 being an optionally substituted bicyclic heteroaryl of the formula (AA) pharmaceutical compositions comprising them and the use thereof as medicaments, in particular for the use as ferroportin inhibitors, more particularly for the use in the prophylaxis and/or treatment of diseases caused by a lack of hepcidin or iron metabolism disorders, such as particularly iron overload states such as in particular thalassemia and hemochromatosis.

Abstract: An airbag assembly for a motor vehicle is provided. The airbag assembly comprises an airbag and a deployable ramp configured to unfurl with the airbag when the airbag is deployed. The deployable ramp is configured to transition from a stowed configuration, in which the deployable ramp is stowed with the airbag before deployment, into a ramped configuration when deployed. The deployable ramp comprises a movable element configured to move in response to the deployment of the airbag from a first position in the stowed configuration, to a second position in the ramped configuration. The movable element is arranged such that a thickness of the deployable ramp increases when the movable element is in the second position and the deployable ramp is positioned and shaped in the ramped configuration to assist the airbag in riding over a component of the vehicle as the airbag is deployed.

Abstract: Apparatuses, methods, systems, and program products are disclosed for resizing interfaces based on eye gaze. A method includes tracking a user's eye gaze using an eye tracking sensor, determining, by a processor, that the user is looking at a pane of a multipane interface based on the user's eye gaze, and dynamically resizing the pane that the user is looking at in response to determining that the user is looking at the pane.

Abstract: The present invention relates to amino acid sequences that block the interaction between (a target on) an antigen presenting cell (APC) and (a target on) a T-cell. More particularly, the present invention relates to amino acid sequences that are directed against (as defined herein) a target on an APC (also referred to herein as “APC target”) or a target on a T-cell (also referred to herein as “T-cell target”). The invention further relates to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences.

Abstract: Described herein is a coupling device, associated parts and a method of use thereof. In one aspect, a coupling device is described comprising a sleeve with an inner surface that encloses at least part of at least one elongated element to be coupled; and at least one deformation means fitted with interference between, and causing local deformation about, at least part of the inner surface of the sleeve and/or an adjacent outer surface of the at least one elongated element. A deformation means insertion tool, a coupling sleeve, a deformation means, and a method of coupling at least one element are also described. The described coupling device, associated parts and a method of use offer the ability to couple together different elements in a strong and/or ductile manner, coupling being tuneable as needed to suit the preferred application. The coupling described may overcome art issues associated with bulky size of coupling, in particular, radial protrusion.

Abstract: A side-curtain airbag for motor vehicles has cushion that, when inflated, is positioned in spaced alignment with a side window. At least one spacer is located at a distal end of the cushion and is in fluid communication therewith. The spacer contacts a portion of the vehicle structure adjacent to the window and positions the cushion in the desired spaced relationship with the side window. The disclosed airbag provides greater resistance to impact and thereby reduces the distance of travel of the head of a motor vehicle occupant beyond the side window glass during a side impact collision.

Abstract: The present disclosure relates to systems, apparatuses, and methods for assembling cartridges for aerosol delivery devices. The cartridges may be assembled by coupling a base of the cartridge to a carriage that is transported via a track. The track transports the carriages between various substations at which one or more parts are added to the base. The carriage may be lifted from the track by a lifter mechanism at each substation in order to perform assembly operations on the base. An inspection system may inspect the cartridges at various stages of completion at or between the various substations.

Abstract: A laser cuts overlapping ribbons of acoustic material into acoustic devices. An automatically controlled manipulator includes an end effector having groups of placement tools for simultaneously placing multiple acoustic devices in a cellular core. The placement tools include mandrels provided with vacuum pickups for picking up and holding the acoustic devices during transport to the core. A vision system aligns the placement tools with the cells of the core. The end effector includes a thermal radiation device for bonding the acoustic devices to the core.

Abstract: An apparatus for rotating an inner stamped part with respect to an outer stamped part is provided. The inner stamped part is nested within an aperture formed within the outer stamped part. The apparatus includes a plurality of grippers that include at least a first gripper positioned at a first edge of the inner stamped part and a second gripper positioned at a second edge of the inner stamped part opposite to the first edge. The plurality of grippers is configured to grip the inner stamped part at the first edge and the second edge, respectively. The plurality of grippers is further configured to rotate the gripped inner stamped part about an axis of rotation. The axis of rotation intersects the first gripper and the second gripper. The plurality of grippers is also configured to open to release the inner stamped part.

Abstract: The present disclosure relates to systems, apparatuses, and methods for assembling cartridges for aerosol delivery devices. The cartridges may be assembled by coupling a base of the cartridge to a carriage that is transported via a track. The track transports the carriages between various substations at which one or more parts are added to the base. The carriage may be lifted from the track by a lifter mechanism at each substation in order to perform assembly operations on the base. An inspection system may inspect the cartridges at various stages of completion at or between the various substations.

Abstract: The present disclosure relates to systems, apparatuses, and methods for assembling cartridges for aerosol delivery devices. The cartridges may be assembled by coupling a base of the cartridge to a carriage that is transported via a track. The track transports the carriages between various substations at which one or more parts are added to the base. The carriage may be lifted from the track by a lifter mechanism at each substation in order to perform assembly operations on the base. An inspection system may inspect the cartridges at various stages of completion at or between the various substations.

Abstract: Methods, systems and devices that generate differential axial transport in a fluidic device having at least one fluidic sample separation flow channel and at least one ESI emitter in communication with the at least one sample separation flow channel. In response to the generated differential axial transport, the at least one target analyte contained in a sample reservoir in communication with the sample separation channel is selectively transported to the at least one ESI emitter while inhibiting transport of contaminant materials contained in the sample reservoir toward the at least one ESI emitter thereby preferentially directing analyte molecules out of the at least one ESI emitter. The methods, systems and devices are particularly suitable for use with a mass spectrometer.

Abstract: Portable analytical equipment, systems, methods, and techniques related thereto is disclosed. Portable analytical equipment can comprise a controller and a probe. The probe can interrogate a sample and receive a response to the interrogation. The controller can select and/or initiate an analysis related to interrogating the sample via the probe. The analysis can be selected from a portfolio of analyses stored on the controller. The controller can analyze the response to the interrogation based on reference data stored on the controller. The controller can determine an indication based on the analyzing the response for presentation via a low-power interface, which can comprise an LED or electrophoretic element. The controller can further be connected to an external device, e.g., a smartphone or remote PC, to present collected data and the analyzing of the response to the interrogation. The disclosed subject matter can be employed in hand-held analytical equipment, e.g., a hand-held Raman spectrometer.

Abstract: Robotic surgical tools can incorporate a latching mechanism as a secondary fastener to maintain operable coupling between the robotic surgical tool and a mounting fixture of a robotic manipulator. Such robotic surgical tools may comprise: a tool housing, an elongate shaft extending from the tool housing, and a latching mechanism arranged on the elongate shaft. The latching mechanism comprises one or more retention tabs that are biased radially outward with one or more biasing members. The one or more retention tabs are configured to transition between a retracted state and a deployed state under influence of a biasing force supplied by the one or more biasing members. In the deployed state, the one or more retention tabs are positioned to engage an exterior surface of a mounting fixture of a robotic manipulator. In the retracted state, the one or more retention tabs are positioned to disengage from the mounting fixture.

Abstract: Provided are compositions and methods for treating diseases, e.g., cancers, e.g., diseases associated with expression of an antigen, e.g., CD 19, comprising administering a cell that expresses a chimeric antigen receptor (CAR) specific to the antigen, e.g., CD19, in combination with a PD-1 inhibitor.

Abstract: Examples disclosed herein relate to determining malware using firmware of a computing device. Firmware can be used to determine that an indication is present that malware is present on the computing device. The firmware can be executed to perform a security action in response to the indication that malware is present on the computing device.

Abstract: Pharmaceutical compositions for intraocular injection are described, the compositions comprise therapeutically effective quantity of lyophilized preservative-free and sulfite-free epinephrine or adrenaline and a metal chelator. Methods for fabricating the compositions and using them for intraocular injections are also described.

Abstract: Systems, media, and methods for providing an interactive health portal for presentation of health information of an individual including: an animated three-dimensional avatar of the individual and at least one of the following distinct navigational modes for navigating a plurality of categories of health information, each category having at least one subcategory of health information, the modes including: a list navigational mode; a two-dimensional map navigational mode; and a three-dimensional landscape navigational mode; wherein the individual can switch between the navigational modes.