Abstract: Individual hexagonal shaped modules used in an assembly for underground storage of storm water and other fluid storage needs. Modules are assembled into a resultant honeycomb shape for maximized structural strength and material use efficiency. Adjacent modules are in direct fluid communications with one another via openings or windows in module side walls. Assemblies include various top and side pieces along with access ports for entry into said assembly.

Abstract: A monitoring system for monitoring a machine, the monitoring system including at least one monitoring device and one or more processing systems. The monitoring device includes a housing, a coupling that physically attaches the housing to the machine, a plurality of sensors, the plurality of sensors including a vibration sensor that senses vibration transmitted from the machine to the vibration sensor at least in part via the coupling, a monitoring device processor that acquires sensors signals from the plurality of sensors and generates sensor data at least partially in accordance with signals from the sensors, and a transmitter that transmits the sensor data. The one or more processing systems receive the sensor data, analyse the sensor data to determine a machine status and either store an indication of the machine status as part of machine status data associated with respective machine or cause a status indication indicative of the machine status to be displayed.

Abstract: A first server includes a processor and a memory accessible to the processor. The memory bears instructions executable by the processor to determine that a server is present that has not had settings other than at most default settings applied to a basic input output system (BIOS) executable by the server to boot the server. The instructions are also executable by the processor to, based at least in part on a determination that the server is the same model of server as the apparatus, has the same BIOS version as the apparatus, and/or has the same baseboard management controller (BMC) version as the apparatus, facilitate over a peer to peer server network at least some settings in the apparatus to be provisioned to the server to establish the at least some settings in the server.

Abstract: In one aspect, a device includes at least one processor, a display accessible to the at least one processor, and storage accessible to the at least one processor. The storage includes instructions executable by the at least one processor to receive input regarding an object at which one person is looking and to present, to another person via the display, a graphical indication regarding the object.

Abstract: Combination therapies comprising PD-1 inhibitors and other therapeutic agents used to treat or prevent cancerous conditions and disorders as follow. Combination therapies of three agents which are a PD-1 inhibitor, a CXCR2 inhibitor and a CSF-1/1R binding agent for treating a pancreatic cancer or a colorectal cancer. Combination therapies of three agents which are a PD-1 inhibitor, a CXCR2 inhibitor and an inhibitor of either TIM-3, C-MET or A2aR for treating a pancreatic cancer or a colorectal cancer. Combination therapies of three agents which are a PD-1 inhibitor, a LAG-3 inhibitor and (i) an inhibitor of either TGF-beta, TIM-3, C-MET, IL-1b or MEK or (ii) a GITR agonist or (iii) an A2aR antagonist or (iv) a CSF-1/1R binding agent for treating a breast cancer. Combination therapies of two agents which are a PD-1 inhibitor and a CXCR2 inhibitor for treating a pancreatic cancer, a colorectal cancer, a lung cancer or a breast cancer.

Abstract: A joint for coupling a wing tip to a wing base includes a linking member that extends from a first end to a second end. The linking member first end is coupleable to the wing base, and the linking member second end is coupleable to the wing tip. The linking member defines first second hinge lines that are substantially parallel. The joint also includes at least one actuator. A first end of each at least one actuator is coupled to the linking member, and a second end of each at least one actuator is coupleable to one of the wing base and the wing tip. The at least one actuator is operable to rotate the wing tip about the first and second hinge lines between a first orientation and a second orientation relative to the wing base.

Abstract: Methods and kits for improving tear production are described, along with topical pharmaceutical compositions. In certain instances, the composition comprises pentoxifylline and a pharmaceutically acceptable carrier. The compositions also may further comprise another active agent, such as an anti-bacterial agent, antiviral agent, antifungal agent, or immunosuppressant agent, and combinations thereof.

Abstract: The present invention relates to a pharmaceutical combination which comprises (a) at least one antibody molecule (e.g., humanized antibody molecules) that bind to Programmed Death 1 (PD-1), and (b) at least one c-Met receptor tyrosine kinase inhibitor or pharmaceutically acceptable salt thereof, for simultaneous, separate or sequential administration for the treatment of a proliferative disease, particularly a c-Met dependent proliferative disease; a pharmaceutical composition comprising such combination; a method of treating a subject having a proliferative disease comprising administration of said combination to a subject in need thereof; use of such combination for the treatment of proliferative disease; and a commercial package comprising such combination.

Abstract: A bonded brazing ring secured to an end of a tube having a solvent or a solvent with a binder applied to the surface of the tube, and a method of adhering a brazing ring to a tube using a solvent or a solvent with a binder is provided. The brazing ring is secured to the tube prior to a brazing operation.

Abstract: Method and apparatus for controlling power conditioners in a distributed resource island. In one embodiment, the method comprises comparing, at a power conditioner operating in a de-energized state, an input of the power conditioner to an input threshold, wherein the power conditioner is coupled to an islanded grid; operating the power conditioner, when the input exceeds the input threshold, in a soft-grid mode to generate a touch-safe AC voltage that is coupled to the islanded grid; and activating the power conditioner, based on an impedance of the islanded grid and load demand for the power conditioner, to operate proximate its nominal output voltage.

Abstract: The invention relates to novel ferroportin inhibitors of the general formula (I) pharmaceutical compositions comprising them and the use thereof as medicaments, in particular for the prophylaxis and/or treatment of diseases caused by a lack of hepcidin or iron metabolism disorders, such as particularly iron overload states such as in particular thalassemia and hemochromatosis.

Abstract: A pneumatic method, and associated apparatus, for injecting a discrete sample plug into the separation channel of an electrophoresis microchip (100) is disclosed. In a first step, pressurized gas (90) is applied to the sample (30) and background electrolyte (20) reservoirs such that the pressure is higher there than at the sample waste reservoir (35) to create a focused sample stream at the junction between the sample and separation channels. In a second step, the pressure at the sample reservoir (30) is reduced in order to pneumatically inject the sample plug into the separation channel. The waste reservoir (35) may be connected to a pressure reducing device (91). The methods, systems and devices are particularly suitable for use with a mass spectrometer (200i).

Abstract: The present disclosure relates to the design of phantoms configurable using one or more inserts and to their use in generating images that may be used to compare image quality between different imaging systems. Such phantoms may have a modular design with inserts that may be exchanged one for another within a phantom body.

Abstract: Apparatuses, methods, systems, and program products are disclosed for preventing connections to a locked device. A method includes detecting, by a processor, that an information handling device is placed in a locked mode. The information handling device includes one or more communication interfaces that enable communication while the information handling device is placed in the locked mode. The method includes preventing connections to the one or more communication interfaces while the information handling device is in the locked mode.

Abstract: Methods and kits for improving tear production are described, along with topical pharmaceutical compositions. In certain instances the composition comprises pentoxifylline and a pharmaceutically acceptable carrier. The compositions also may further comprise another active agent, such as an anti-bacterial agent, antiviral agent, antifungal agent, or immunosuppressant agent, and combinations thereof.

Abstract: An X-ray source target includes a structure configured to generate X-rays when impacted by an electron beam. The structure has an X-ray generating layer comprising X-ray generating material, and a thermally-conductive layer is adjacent to and in thermal communication with the X-ray generating layer. A stress relieving layer is adjacent to the thermally-conductive layer. The thermally-conductive layer is sandwiched between the X-ray generating layer and the stress relieving layer.

Abstract: In one aspect, a device includes a processor and a memory accessible to the processor. The memory bears instructions executable by the processor to engage in telephonic communication with at least a second device and a third device and, in response to input to the first device and without the first device concluding the telephonic communication with the second and third devices, enable auditory telephonic communication of the first device with the second device and prevent auditory telephonic communication of the first device with the third device.

Abstract: A dispensing closure system includes an upper closure portion and a lower closure portion including an axial flow conduit and a vent conduit. The upper closure portion is axially movable relative to lower closure portion between shipping and dispensing positions. A seal is disposed on the lower closure portion over the flow and vent conduits. A peripheral spacing strip is removably secured to the upper closure portion and engages with either the lower closure or the outside of the container to prevent movement. A piercing probe includes piercing elements in alignment with the flow and vent conduits for piercing the seal. In the shipping position, the piercing elements are spaced from the seal. However, when the spacing strip is removed and the upper closure portion is axially moved to the dispensing position, the piercing elements pierce the seal to open the flow conduit and the vent conduit.

Abstract: A secure element device for use in a connected device includes a first interface configured to enable communication with a communication module and a second interface configured to enable communication with an action module of the connected device. A processor coupled to the first interface and the second interface, executes a first set of computer-readable instructions, stored in a memory of the secure element device, to authenticate, via the first interface, the connected device on the communication network. The processor also executes a second set of computer-readable instructions, stored in the memory, to perform one or both of (i) obtaining, via the second interface, data from the action module, the data to be transmitted over the communication network and (ii) controlling, via the second interface, the action module to cause the action module to perform one or more operations based on an instruction received over the communication network.

Abstract: The presently disclosed subject matter is directed to a device that can be used to exercise and/or strengthen the muscles of the foot, ankle, and/or leg of a user. The device includes foot-receiving pedal that is sized and shaped to provide support for a user's foot or shoe. The pedal includes a first pair of brackets positioned at the rear of the pedal that allow connection to the support at a joint. The support can include a band that rests against the user's leg to provide comfort during use. The joint allows the pedal to move relative to the support. One or more resistive elements (e.g., springs) attach the support to a second pair of brackets positioned at the front portion of the pedal to provide resistance to the movement of the joint. The support includes an adapter that allows the attachment of the springs to be modified to vary resistance and/or be customized to a user's particular leg shape or length.