Abstract: The present invention is directed to anti-podocalyxin antibodies, compositions comprising the same, and methods of using such antibodies and compositions for the prevention, diagnosis and treatment of cancer.

Abstract: An apparatus and method of operating an apparatus are provided. The apparatus is responsive to a bit-testing instruction which specifies a source vector register and an index to perform a bit-testing procedure on plural elements stored in the source vector register to generate plural result bits. The bit-testing procedure comprises, for each processed element of the plural elements, setting a respective result bit of the plural result bits in dependence on a value of a tested bit at a bit position in the processed element of the source vector register indicated by the index. This bit-testing instruction thus enables increased performance of program code which is required to perform multiple bit tests and can be suitably formulated into a vectorised form.

Abstract: Various systems and methods are provided for utilizing a crankshaft lip seal over the course of a first overhaul life and a second overhaul life. In one example, a method includes installing the crankshaft lip seal between a flywheel housing and a crankshaft of an engine and operating the engine with the crankshaft lip seal. The method further includes removing the crankshaft lip seal, re-machining a floating seal sleeve coupled to the crankshaft or the flywheel housing, and replacing a lip. The crankshaft lip seal is then re-installed between the flywheel housing and the crankshaft and the engine operated with the re-installed crankshaft lip seal.

Abstract: Examples of integrated semiconductor devices are described. In one example, an integrated device includes first and second transistors formed on a substrate, where the transistors share a terminal metal feature to reduce a size of the integrated device. The terminal metal feature can include a shared source electrode metalization, for example, although other electrode metalizations can be shared. In other aspects, a first width of a gate of the first transistor can be greater than a second width of a gate of the second transistor, and the shared metalization can taper from the first width to the second width. The integrated device can also include a metal ground plane on a backside of the substrate, and the terminal metal feature can also include an in-source via for the shared source electrode metalization. The in-source via can electrically couple the shared source electrode metalization to the metal ground plane.

Abstract: A valve for sealing the hub of a sheath assembly is provided. The valve includes a valve body having a solid thickness extending between a proximal surface and a distal surface. A bisecting slot extends across the proximal surface of the valve body and terminates at a depth less than the thickness of the valve body such that a portion of the valve body distally of the slot defines a bridge extending between opposed halves of the valve body such that the distal surface of the valve body is substantially continuous and a central portion of the proximal surface of the valve body is concave and defines a concave proximal portion.

Abstract: A bulk bag conditioner assembly is disclosed herein. The assembly includes a frame assembly defining a bulk bag conditioning area. The frame assembly includes a first carrier frame with a first ram, and a second carrier frame with a second ram. A first actuator assembly includes a first end fixed to the first carrier frame and a second end fixed to the second carrier frame. A second actuator assembly includes a first end fixed to the first carrier frame and a second end fixed to the second carrier frame. A control unit is configured to simultaneously drive the first ram and the second ram linearly towards each other to engage a bulk bag within the bulk bag conditioning area.

Abstract: The present invention is directed to compositions of matter useful for the treatment of cancer in mammals and to methods of using those compositions of matter for the same. Antibodies specific for podocalyxin designated Ab1 and 3G2 are disclosed, as is the use of said antibodies for the inhibition of growth of a tumor that expresses podocalyxin, and the use of said anti bodies for targeting tumour endothelial cells that express podocalyxin.

Abstract: The present disclosure is directed towards systems and method for determining whether a scannable code displayed on a client device has been scanned. In particular, the systems and methods described herein involve activating one or more on-board sensors of the client device to capture output signals. Based on the output signals, the systems and methods include identifying discrete signals that indicate whether the scannable code has been scanned by a scanning device. Further, based on an analysis of the identified discrete signals, the systems and methods include determining whether the scannable code has been scanned by the scanning device.

Abstract: Data processing apparatus comprises vector processing circuitry to selectively apply vector processing operations defined by vector processing instructions to generate one or more data elements of a data vector comprising a plurality of data elements at respective data element positions of the data vector, according to the state of respective predicate flags associated with the positions of the data vector; and generator circuitry to generate instruction sample data indicative of processing activities of the vector processing circuitry for selected ones of the vector processing instructions, instruction sample data indicating at least the state of the predicate flags at execution of the selected vector processing instructions.

Abstract: An optically thin sample of a sample material is analyzed by propagating probe electromagnetic radiation from a beam source along a plurality of different ray paths, directing each ray so that each ray path intersects upon the sample at a plurality of different locations where the rays interact with the sample material to cause a modification of the ray. The rays received at each of a plurality of detection spatial region are measured separately and the measurements analyzed to provide information about at least one property of the sample material at each interaction location. An analysis is carried out to trace the path of probe radiation from a location at the probe beam source to the detection spatial region on the detection surface so as to identify the interaction locations so as to provide information about the presence of target material at each interaction location.

Abstract: A biological sample is analyzed for presence of a causing agent such as a virus, bacteria or cancer which generates a series of different states in the sample. The sample is separated into sub-samples where at least some of the sub-samples include portions of the sample at different states. Electromagnetic radiation interacts with the samples to obtain a spectrum of sub-sample properties which is compared with a plurality of reference spectra obtained from testing a plurality of sub-samples in respective ones of the different states to calculate a population distribution of the states of the sub-samples to obtain information about the causing agent. The population distribution can be analyzed at a single time or temporally over time to generate data relating to an effect of the causing agent. The population distribution is compared with a plurality of reference population distributions to generate data identifying the causing agent.

Abstract: A method of sanitizing fabric-based currency eliminates or significantly reduces pathogens on fabric-based currency. The method is implemented by a system that includes an airtight container including a treatment chamber, a chamber entrance/exit, at least one UV lamp, and an ozone dispensing system. The method begins placing at least one piece of fabric-based currency through the chamber entrance/exit and into the treatment chamber. The piece of fabric-based currency is hermetically sealed within the treatment chamber by closing the chamber entrance/exit. The piece of fabric-based currency is then exposed to at least one quantity of UV radiation for a specified period of time. The piece of fabric-based currency is exposed to a quantity of ozone for another specified period of time by pumping the quantity of ozone into the treatment chamber. The chamber entrance/exit is finally opened, and the piece of fabric-based currency is removed from the treatment chamber.

Abstract: A data processing apparatus, a method of operating a data processing apparatus, a non-transitory computer readable storage medium, and an instruction are provided. The instruction specifies a first source register, a second source register, and an index. In response to the instruction control signals are generated, causing processing circuitry to perform a data processing operation with respect to each data group in the first source register and the second source register to generate respective result data groups forming a result of the data processing operation. Each of the first source register and the second source register has a size which is an integer multiple at least twice a predefined size of the data group, and each data group comprises a plurality of data elements. The operands of the data processing operation for each data group are a selected data element identified in the data group of the first source register by the index and each data element in the data group of the second source register.

Abstract: In one embodiment, the disclosed apparatus is a heat-pipe cooling system that includes a conical structure having an upper portion that is truncated. The conical structure is configured to be formed above a dielectric window with the conical structure being configured to condense vapor from a heat-transfer fluid placed or formed within a volume formed between the dielectric window and the conical structure. At least one cooling coil is formed on an exterior portion of the conical structure. Other apparatuses and systems are disclosed.

Abstract: The present disclosure is directed towards systems and method for determining whether a scannable code displayed on a client device has been scanned. In particular, the systems and methods described herein involve activating one or more on-board sensors of the client device to capture output signals. Based on the output signals, the systems and methods include identifying discrete signals that indicate whether the scannable code has been scanned by a scanning device. Further, based on an analysis of the identified discrete signals, the systems and methods include determining whether the scannable code has been scanned by the scanning device.

Abstract: A support apparatus for supporting a trocar while the trocar extends through a body wall of a patient includes an inflatable collar and a slidable abutment collar commonly connected for engagement onto the trocar following which the slide collar is released to slide along the trocar. The inflatable collar is inflated to a set size by a manually operable pump on the slidable collar operated by squeezing finger abutments together up to a latch so that threaded portion expels the inflation fluid. The abutment member is shaped to be received on an outer surface of the trocar and adjustable longitudinally of the trocar sleeve so as to be located at a selected position by a manually movable latch collar. The inflatable collar and slidably collar are held connected by a manually operable release.

Abstract: A data processing system 2 supporting vector processing operations uses scaling vector length querying instructions. The scaling vector length querying instructions return a result which is dependent upon a number of elements in a vector for a variable vector element size specified by the instruction and multiplied by a scaling value specified by the instruction. The scaling vector length querying instructions may be in the form of count instructions, increment instructions or decrement instructions. The instructions may include a pattern constraint applying a constraint, such as modulo(M) or power of 2 to the partial result value representing the number of vector elements provided for the register element size specified for the instruction.

Abstract: A valve actuation system for an engine includes a rotatable camshaft, an injector actuation linkage, and a valve actuation linkage. The valve actuation linkage includes a valve lifter, a valve pushrod, and a rocker arm. At least one of a rocker arm center plane defined by the valve rocker arm or a lifter roller center plane defined by the valve lifter is spaced an offset distance from a pushrod axis, providing an increased contact width between an injector roller in the injector actuation linkage and one of a plurality of cam lobes of the camshaft. The valve lifter includes a fork defining a center plane spaced an offset distance from a center axis of the valve lifter. A rocker arm includes a screw bore offset relative to a rocker arm center plane.

Abstract: A shelving system and its method of formation. The shelving system comprises a shelf including a support plate, a front edge lip connected to a front portion of the support plate, and a back support edge connected to a back portion of the support plate. The back support edge has an elongated slot. A divider is mounted on the support plate and includes a main portion having a first end and a second end, with a first tab attached to the main portion at the first end and engaging a slit in the front edge lip and a second tab attached to the main portion at the second end, the second tab being provided with a flange, said flange being formed with a hole. A fastener passes through the hole in the flange and the elongated slot in the back support edge to adjustably secure the divider to the shelf.