Abstract: Embodiments of the present disclosure provides protocols, methods and systems which provides advantages such as the resistance of centralisation of mining on a blockchain network, preferably a Proof-of-Work blockchain. A method in accordance with an embodiment may comprise generating a plurality of non-parallelisable challenges (or “puzzles”) and allocating one of said plurality of challenges to each miner on the network. The miner uses an inherently sequential (non-parallelisable) algorithm to find a solution to his allocated challenge. The challenges are generated by a committee of nodes, and a new set of challenges is generated for each block.

Abstract: A computer-implemented method for analyzing a vehicle trip is presented. The method may include obtaining a wireless communication address of a vehicle of an insured driver. One or more processors may determine whether the wireless communication address corresponds to one of one or more known vehicles associated with an insured driver. Responsive to determining that the wireless communication address corresponds to one of the one or more known vehicles associated with the insured driver, the one or more processors may collect a plurality of vehicle telematics data during the vehicle trip. The one or more processors may also analyze the plurality of vehicle telematics data to determine at least one driving behavior of the insured driver.

Abstract: Disclosed is an improved method, system, and computer program product for identifying malicious payloads. The disclosed approach identifies potentially malicious payload exchanges which may be associated with payload injection or root-kit magic key usage.

Abstract: An insulating container having a base and a lid is provided. The lid may be rotatable about a hinge from a closed configuration to an open configuration and may be secured, via one or more latching devices, in the closed configuration. In some examples, the insulating container further includes a pull handle assembly with a telescopic three-stage arm configuration defined by a stowed configuration, a partially extended configuration, and a fully extended configuration. In other examples, the insulating container further includes a wheel assembly with a pair of wheels mounted with one or two axles, and further including a wheel grommet for absorbing shock and cushioning the axle. In still other examples, the insulating container further includes a drain plug assembly on the rear sidewall adjacent to the bottom portion of the base, the drain plug assembly comprising a main tube that cooperatively engages with an outer tube with a plurality of ratchet teeth that engage one or more ratchet keys on the main tube.

Abstract: A method includes transmitting a request for a computer-readable routing diagram, such as a wiring diagram, a pneumatic or hydraulic line diagram, or an optical cable diagram. The method also includes receiving, in response to the request, a routing diagram including a connectable component and at least a portion of a routing set. The connectable component is associated with both a connectable component identifier and the routing set. The routing set contains one or more routable components, such as electrical circuits, pneumatic or hydraulic lines, or optical cables. Further, the method includes displaying, on a display, the routing diagram and at least the portion of the routing set highlighted. Displaying at least the portion of the routing set highlighted occurs in response to an occurrence of the connectable component being selected from the routing diagram displayed on the display or in response to the request including the connectable component identifier.

Abstract: Systems and methods for delivering multiple ocular implants to reduce intraocular pressure are disclosed. The ocular implants can be implanted at multiple sites within a single human eye without requiring removal of the delivery apparatus from the eye. A system for delivering multiple ocular implants can include at least two implants preloaded within a delivery device and configured to be implanted within the eye, a metering device configured to transfer energy to the implants for delivery at selected locations within the eye, wherein the metering device is configured to meter a variable amount of energy for each implant delivery event in the eye. The system can further include an injector mechanism configured to serially engage and drive each of the implants.

Abstract: A tethered device for prevention and recovery of a vehicle component (e.g., a catalytic converter) is provided herein. The tethered device comprises a housing having an exterior surface and defining an interior cavity. The tethered device further comprises an electronic component disposed within the interior cavity. The tethered device further comprises a plurality of spacers extending from the exterior surface and configured to be adjacent to the vehicle component. The plurality of spacers defines a channel configured to promote airflow between the tethered device and the vehicle component thereby minimizing heat transfer between the tethered device and the vehicle component.

Abstract: Ingestible devices can directly deliver therapeutic agents to desired tissue(s) of the GI tract of a subject, such as the submucosa, the mucosa, and/or the mucus layer of the GI tract, and methods of using the same. The ingestible devices can deliver therapeutic agents in a safe, effective, and reliable manner. The disclosure also provides pharmaceutical compositions for use in methods of treating a disease or condition in a subject in need thereof.

Abstract: An optical scanning system and method are provided that may include an optical scanning attachment coupled to a digitizing arm for use in a three-dimensional (3D) scan of a surface of a partially closed volume. The optical scanning attachment including at least one laser operable to generate a laser light at a frequency. The optical scanning attachment further includes at least one optical element operable to receive the laser light and create a light pattern. The optical scanning attachment further includes at least one camera including a lens and configured to receive an image of the light pattern on the surface of the partially closed volume. The optical scanning attachment further includes an elongated member having a proximal and a distal end, wherein the proximal end is positioned closer to the digitizing arm as compared to the distal end, wherein the at least one laser is positioned so that external laser light emanates adjacent the distal end of the elongated member.

Abstract: A battery pack assembly includes a first cell stack having a first side and a second side. The first side is transverse to the second side. A second cell stack is adjacent the first side of first cell stack. A divider has a barrier portion and an attachment portion. The barrier portion is disposed between the first side of the first cell stack and the second cell stack. The attachment portion is secured directly to the second side of the first cell stack.

Abstract: A technique is provided for determining a loss risk assessment score for a vehicle trip. The technique includes, at a vehicle, a computing device receiving first information indicative of operation of the vehicle. The technique also includes, at the vehicle, the computing device receiving second information indicative of an environment at a particular location and time. The computing device correlates the first information and the second information to generate a data set. The technique also includes determining a score for the vehicle trip based at least in part upon the generated data set.

Abstract: Communications where one or more of the participants are at least partially anonymized. For example, various embodiments allow for the hiding of facial features, the distortion of voice characteristics, or both, while still allowing substantive communication.

Abstract: Mice, embryos, cells, and tissues having a restricted immunoglobulin heavy chain locus and an ectopic sequence encoding one or more ADAM6 proteins are provided. In various embodiments, mice are described that have humanized endogenous immunoglobulin heavy chain loci and are capable of expressing an ADAM6 protein or ortholog or homolog or functional fragment thereof that is functional in a male mouse. Mice, embryos, cells, and tissues having an immunoglobulin heavy chain locus characterized by a single human VH gene segment, a plurality of human DH gene segments and a plurality of human JH gene segments and capable expressing an ADAM6 protein or ortholog or homolog or functional fragment thereof are also provided.

Abstract: A method of dispensing a graded material includes generating droplets of a first working material, the droplets having a size in the range of 10 nanometers to 10 micrometers, adding the droplets of the first working material into a carrier fluid to create a first emulsion, wherein addition of the droplets of the first working material is controlled to create gradient in the emulsion, mixing the first emulsion to create a homogenous, graded mixture, and dispensing the homogenous, graded mixture onto a surface.

Abstract: The present invention is directed to a prolipid composition that penetrates the stratum corneum. More particularly, the invention is directed to a prolipid composition that provides personalized benefits by rapidly restoring the skins natural lipid balance. Such a composition results in elongated fatty acid and/or lipid production deep in the stratum corneum and near the surface of the stratum lucidum. The composition at least comprises a fatty acid, fatty ester and/or an acylglycerol and an activator of a peroxisome proliferator-activated receptor.

Abstract: This disclosure generally relates to an optical coherence tomography (OCT) system. This disclosure particularly relates to an OCT system with a multi-pass dispersion compensation cell incorporated into its reference arm. This disclosure further relates to a hand-held compact OCT system suitable for inspection of an ear of a mammal.

Abstract: Systems, devices and processes are provided to improve the design and implementation of radio frequency (RF) communication networks. Specifically, these various embodiments improve the likelihood of a successful RF network design by identifying and preferentially utilizing RF transmission sites having a relatively high probability of being successfully incorporated into the RF network. These various embodiments provide a site qualification database that includes site data for a plurality of RF transmission sites. When so implemented, the site qualification database is utilized to analyze the site data and generate a plurality of site scores for the corresponding RF transmission site, which can then be utilized in an RF analysis.

Abstract: A computer-implemented method for analyzing a vehicle trip is presented. The method may include obtaining a wireless communication address of a vehicle of an insured driver. One or more processors may determine whether the wireless communication address corresponds to one of one or more known vehicles associated with an insured driver. Responsive to determining that the wireless communication address corresponds to one of the one or more known vehicles associated with the insured driver, the one or more processors may collect a plurality of vehicle telematics data during the vehicle trip. The one or more processors may also analyze the plurality of vehicle telematics data to determine at least one driving behavior of the insured driver.