Patents by Inventor John T. Groves

John T. Groves has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9701557
    Abstract: Methods, kits, cartridges and compounds related to generating chlorine dioxide by exposing ClO2? to at least one of a manganese porphyrin catalyst or a manganese porphyrazine catalyst are described. Methods, kits, cartridges and compounds related to decomposed cyanide ions and hydrogen cyanide for water decontamination.
    Type: Grant
    Filed: October 9, 2014
    Date of Patent: July 11, 2017
    Assignee: The Trustees of Princeton University
    Inventors: John T. Groves, Thomas P. Umile
  • Publication number: 20170152207
    Abstract: Embodiments of the present disclosure provide for methods of hydrocarbon functionalization, methods and systems for converting a hydrocarbon into a compound including at least one group ((e.g., hydroxyl group) (e.g., methane to methanol)), functionalized hydrocarbons, and the like.
    Type: Application
    Filed: February 14, 2017
    Publication date: June 1, 2017
    Inventors: Thomas Brent Gunnoe, George Fortman, Nicholas C. Boaz, John T. Groves
  • Patent number: 9604890
    Abstract: Embodiments of the present disclosure provide for methods of hydrocarbon functionalization, methods and systems for converting a hydrocarbon into a compound including at least one group ((e.g., hydroxyl group) (e.g., methane to methanol)), functionalized hydrocarbons, and the like.
    Type: Grant
    Filed: June 26, 2014
    Date of Patent: March 28, 2017
    Assignees: The Trustees of Princeton University, University of Virginia Patent Foundation
    Inventors: Thomas Brent Gunnoe, George Fortman, Nicholas C. Boaz, John T. Groves
  • Patent number: 9527734
    Abstract: Methods, kits, cartridges and compounds related to generating chlorine dioxide by exposing ClO2? to at least one of a manganese porphyrin catalyst or a manganese porphyrazine catalyst are described.
    Type: Grant
    Filed: August 19, 2011
    Date of Patent: December 27, 2016
    Assignee: THE TRUSTEES OF PRINCETON UNIVERSITY
    Inventors: John T. Groves, Thomas P. Umile
  • Publication number: 20160340189
    Abstract: Methods, kits, cartridges, and compounds related to generating chlorine dioxide by exposing ClO2? to at least one of an iron porphyrin catalyst or an iron porphyrazine catalyst are described.
    Type: Application
    Filed: August 4, 2016
    Publication date: November 24, 2016
    Applicant: The Trustees of Princeton University
    Inventors: John T. Groves, Roy Xiao
  • Publication number: 20160264512
    Abstract: Fluorinated compounds are provided. Fluorinated compounds may be prepared by a method of halogenating a carbon containing compound having an sp3 C—H bond.
    Type: Application
    Filed: October 9, 2014
    Publication date: September 15, 2016
    Applicant: The Trustees of Princeton University
    Inventors: John T. Groves, Wei Liu, Xiongyi Huang
  • Publication number: 20160158388
    Abstract: Methods of preparing fluorinated compounds by carboxylative fluorination using fluoride are contained herein. Fluorinated compounds are provided. Methods of using fluorinated compounds are contained herein.
    Type: Application
    Filed: February 9, 2016
    Publication date: June 9, 2016
    Applicant: The Trustees of Princeton University
    Inventors: John T. Groves, Xiongyi Huang
  • Publication number: 20160145188
    Abstract: Embodiments of the present disclosure provide for methods of hydrocarbon functionalization, methods and systems for converting a hydrocarbon into a compound including at least one group ((e.g., hydroxyl group) (e.g., methane to methanol)), functionalized hydrocarbons, and the like.
    Type: Application
    Filed: June 26, 2014
    Publication date: May 26, 2016
    Inventors: THOMAS BRENT GUNNOE, GEORGE FORTMAN, NICHOLAS C. BOAZ, JOHN T. GROVES
  • Publication number: 20150090672
    Abstract: Methods, kits, cartridges and compounds related to generating chlorine dioxide by exposing ClO2? to at least one of a manganese porphyrin catalyst or a manganese porphyrazine catalyst are described. Methods, kits, cartridges and compounds related to decomposed cyanide ions and hydrogen cyanide for water decontamination.
    Type: Application
    Filed: October 9, 2014
    Publication date: April 2, 2015
    Inventor: John T. Groves
  • Patent number: 8962344
    Abstract: A membrane-coated particle composition and methods comprising a particle surrounded by a native cell membrane are disclosed. The cell membrane may contain selected receptors or binding components. At least a portion of the receptors or binding components are oriented on the membrane-coated particle in the same or similar orientation as in the native cell membrane. The membrane-coated particle(s) finds use, for example, in contexts of basic research, proteomics, drug discovery, drug delivery, medical diagnostics, and aspects of patient care.
    Type: Grant
    Filed: March 16, 2009
    Date of Patent: February 24, 2015
    Assignee: Synamem Corporation
    Inventors: John T. Groves, Jeremy T. Blitzer
  • Publication number: 20150031768
    Abstract: Methods of halogenating a carbon containing compound having an sp3 C—H bond are provided. Methods of fluorinating a carbon containing compound comprising halogenation with Cl or Br followed by nucleophilic substitution with F are provided. Methods of direct oxidative C—H fluorination of a carbon containing compound having an sp3 C—H bond are provided. The halogenated products of the methods are provided.
    Type: Application
    Filed: October 9, 2014
    Publication date: January 29, 2015
    Inventors: John T. Groves, Wei Liu, Xiongyi Huang
  • Publication number: 20140249329
    Abstract: Methods of halogenating a carbon containing compound having an sp3 C—H bond are provided. Methods of fluorinating a carbon containing compound comprising halogenation with Cl or Br followed by nucleophilic substitution with F are provided. Methods of direct oxidative C—H fluorination of a carbon containing compound having an sp3 C—H bond are provided. The halogenated products of the methods are provided.
    Type: Application
    Filed: August 20, 2012
    Publication date: September 4, 2014
    Applicant: The Trustees of Princeton University
    Inventors: John T. Groves, Wei Liu
  • Publication number: 20140227184
    Abstract: Methods of halogenating a carbon containing compound having an sp3 C—H bond are provided. Methods of fluorinating a carbon containing compound comprising halogenation with Cl or Br followed by nucleophilic substitution with F are provided. Methods of direct oxidative C—H fluorination of a carbon containing compound having an sp3 C—H bond are provided. The halogenated products of the methods are provided.
    Type: Application
    Filed: August 20, 2012
    Publication date: August 14, 2014
    Applicant: The Trustees of Princeton University
    Inventors: John T. Groves, Wei Liu, Xiongyi Huang
  • Publication number: 20140106469
    Abstract: The present invention provides a sensor for detecting the binding of molecules to membrane surfaces. The sensor comprises a nanoparticle coated with a continuous layer of silica, and having a ligand attached thereto, for detection of an analyte in a solution. The nanoparticle can be further coated with a continuous membrane, such as a lipid bilayer.
    Type: Application
    Filed: October 11, 2013
    Publication date: April 17, 2014
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Hung-Jen Wu, John T. Groves
  • Publication number: 20130209573
    Abstract: Methods, kits, cartridges and compounds related to generating chlorine dioxide by exposing ClO2? to at least one of a manganese porphyrin catalyst or a manganese porphyrazine catalyst are described.
    Type: Application
    Filed: August 19, 2011
    Publication date: August 15, 2013
    Applicant: THE TRUSTEES OF PRINCETON UNIVERSITY
    Inventor: John T. Groves
  • Patent number: 8389231
    Abstract: Assays for the identification of antibacterial agents that inhibit mycobacterial growth by interfering with the iron acquisition pathway in host cells are disclosed. Also disclosed are methods of inhibiting mycobacterial growth by interfering with iron uptake or by delivering antibacterial agents to mycobacteria in host cells through the iron uptake pathway, as well as certain compounds that are useful in the assay methods, and also as antibacterial agents.
    Type: Grant
    Filed: August 23, 2006
    Date of Patent: March 5, 2013
    Assignee: The Trustees of Princeton University
    Inventor: John T. Groves
  • Patent number: 8334377
    Abstract: This invention provides a novel class of substituted macrocyclic metallic compounds. The compounds are useful as peroxynitrite decomposition catalysts. Pharmaceutical compositions, and methods of making and using the compounds, or a pharmaceutically acceptable salt, hydrate, or prodrug thereof are also described.
    Type: Grant
    Filed: October 5, 2007
    Date of Patent: December 18, 2012
    Assignee: The Trustees of Princeton University
    Inventor: John T. Groves
  • Publication number: 20120283236
    Abstract: This invention provides a novel class of substituted macrocyclic porphyrin compounds. The compounds are useful as peroxynitrite decomposition catalysts. Pharmaceutical compositions, and methods of making and using the compounds, or a pharmaceutically acceptable salt, hydrate, or prodrug thereof are also described.
    Type: Application
    Filed: June 26, 2012
    Publication date: November 8, 2012
    Inventor: John T. Groves
  • Publication number: 20120208174
    Abstract: Detection and characterization of molecular interactions on membrane surfaces is important to biological and pharmacological research. In one embodiment, silver nanocubes interfaced with glass-supported model membranes form a label-free sensor that measures protein binding to the membrane. The present device and technique utilizes plasmon resonance scattering of nanoparticles, which are chemically coupled to the membrane. In contrast to other plasmonic sensing techniques, this method features simple, solution-based device fabrication and readout. Static and dynamic protein/membrane binding are monitored and quantified.
    Type: Application
    Filed: August 5, 2011
    Publication date: August 16, 2012
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: William J. Galush, Sarah A. Shelby, Martin J. Mulvihill, Andrea R. Tao, Peidong Yang, John T. Groves
  • Patent number: 8232267
    Abstract: This invention provides a novel class of substituted macrocyclic porphyrin compounds. The compounds are useful as peroxynitrite decomposition catalysts. Pharmaceutical compositions, and methods of making and using the compounds, or a pharmaceutically acceptable salt, hydrate, or prodrug thereof are also described.
    Type: Grant
    Filed: October 5, 2007
    Date of Patent: July 31, 2012
    Assignee: The Trustees of Princeton University
    Inventor: John T. Groves