Abstract: An apparatus for filtering radio frequency signals is provided. The apparatus includes a substrate and a membrane coupled to the substrate that includes piezoelectric material. The apparatus also includes an interdigital transducer (IDT) coupled to the membrane and includes a plurality of interleaved fingers. The apparatus also includes a lid, in which the membrane is arranged between the substrate and the lid with a first cavity having a first height between the lid and a first main surface of the membrane and a second cavity having a second height between the substrate and a second main surface of the membrane that opposes the first main surface. Moreover, the first height between the lid and the first main surface of the membrane is greater than a pitch of at least one pair of interleaved fingers of the plurality of interleaved fingers and at most four times greater than the second height.

Abstract: The present disclosure relates generally to pharmaceutical compositions comprising cannabidiol (CBD), ?-9-tetrahydrocannabinol (THC) and linalool. In some embodiments, the pharmaceutical compositions are useful in the treatment of an inflammatory condition, e.g., useful for the treatment of pain.

Abstract: The disclosure relates to a sterilization apparatus which uses thermal or non-thermal plasma to disinfect surgical scoping devices such as endoscopes, gastroscopes, laparoscopes and the like. Aspect of the disclosure provide: (i) an apparatus for sterilizing inside an instrument channel formed with an insertion tube of a surgical scoping device, (ii) a whole-device sterilization apparatus for treating the entire exterior surface of a surgical scoping device, and (iii) an apparatus for cleaning and sterilizing a distal end face of an insertion tube of a surgical scoping device.

Abstract: The invention relates to a new method of delivering an analyte to a transmembrane pore in a membrane. The method involves the use of microparticles.

Abstract: A treatment apparatus which uses thermal or non-thermal plasma to treat urinary tract infections (UTIs) by destroying bacteria. The apparatus comprises an elongate probe that includes a coaxial cable for conveying radiofrequency (RF) electromagnetic (EM) energy and/or microwave EM energy, a probe tip connected at the distal end of the coaxial cable for receiving the RF and/or microwave EM energy, and a gas conduit for conveying gas to the probe tip. The probe tip comprises a first electrode connected to the inner conductor of the coaxial cable, and a second electrode connected to the outer conductor of the coaxial cable, and wherein the first electrode and second electrode are arranged to produce an electric field from the received RF and/or microwave EM energy across a flow path of gas received from the gas conduit to produce a thermal or a non-thermal plasma.

Abstract: A method of forming an inorganic oxide coating on a monolith article is disclosed. The coated monolith article is suitable for the treatment of an exhaust gas. The method comprises spraying, as a dry particulate aerosol, inorganic particles comprising an aluminosilicate zeolite having a SAR of greater than 100:1 and a silicone resin to form a coating layer. The present invention also provides an uncalcined porous monolith article for use in forming a monolith article for the treatment of an exhaust gas. The uncalcined monolith article comprises a dry particulate composition comprising inorganic particles and a silicone resin.

Abstract: A method for determining the presence, absence or amount of two or more target polynucleotides in a sample comprising additional components, the method comprising: (i) contacting the sample with a panel of two or more probes under conditions suitable for hybridisation of the target polynucleotides to the probes, wherein: (a) each probe comprises a non-hybridisation region and a hybridisation region that specifically hybridises to one of the target polynucleotides to form a hybridised probe; and (b) the hybridisation region of a probe of the panel comprises one or more non-natural nucleotides; (ii) contacting the sample prepared in step (i) with a transmembrane pore through which a single stranded polynucleotide but not a double stranded polynucleotide can pass and applying a potential difference to the transmembrane pore such that the hybridised probes in the sample interact with the pore; (iii) measuring current blockades having a duration within a defined window, wherein: (a) the one or more non-natu

Abstract: One embodiment provides a method and a system for diagnosing faults in a physical system. During operation, the system can create a fault-augmented model of the physical system by considering various potential faults, and it can generate a machine-learning model to predict an operation mode of the physical system using the outputs of the physical system. A respective operation mode corresponds to normal operation or a potential fault in the physical system. The system can generate a plurality of training samples based on the fault-augmented model, use the training samples to train the machine-learning model to learn a sequence of inputs and model parameters that minimizes an uncertainty of the predicted operation mode, and then apply the learned sequence of inputs and the trained machine-learning model on the physical system to determine the operation mode of the physical system.

Abstract: A modular drone containment system including a plurality of modular stacked drone containers. Each modular drone container is configured to house a drone device and be removably disposed in a stacked orientation relative to one another. Each modular container includes a sidewall having a continuous upstanding wall defining a containment space configured to house a respective drone device. A topmost modular container in the stacked orientation further includes a top cover pivotally attached to a top portion of its sidewall. A bottommost modular container in the stacked orientation includes a bottom wall attached to a bottom portion of its sidewall. Further included is a charging system configured to simultaneously charge a battery provided in each drone housed in a stacked modular container.

Abstract: Proposed is a digital and automated underwriting system and method with fast point of sale decision-making and intelligent data processing engine for the coverage of possible damage impacted by the occurrence of health events to users. The automated system captures user-specific medical parameter data sets. The captured medical parameter data sets are processed by the electronic signal processing engine, wherein the electronic signal processing engine transmits an output signal generated upon processing the medical parameter data set, the output signal automatically triggering or blocking an automated underwriting process by an electronic underwriting unit.

Abstract: This disclosure provides techniques for providing or facilitating automatic generation or conversion to geometric designs based on system-level designs. An example method may include receiving a system model from a system modeling environment. The system model describes, represents, or reflects a typology of two or more system components. The topology describes connectivity and performance by the two or more system components. A processing device extracts the topology of the two or more system components from the system model. The topology is represented by two or more connected nodes. The topology describes connectivity and performance by two or more system components. The processing device generates design spaces for the two or more connected nodes. The processing device further generates geometric representations in the design spaces for each of the two or more connected nodes to form the geometric assembly based on the system model.

Abstract: The invention relates to new methods of attaching one or more polynucleotide binding proteins to a target polynucleotide. The invention also related to new methods of characterising target polynucleotides.

Abstract: Aspects of the present disclosure relate to an apparatus comprising processing circuitry, first cache circuitry and second cache circuitry, wherein the second cache circuitry has an access latency higher than an access latency of the first cache circuitry. The second cache circuitry is responsive to receiving a request for data stored within the second cache circuitry to identify said data as pseudo-invalid data and provide said data to the first cache circuitry. The second cache circuitry is responsive to receiving an eviction indication, indicating that the first cache circuitry is to evict said data, to, responsive to determining that said data has not been modified since said data was provided to the first cache circuitry, identify said pseudo-invalid data as valid data.

Abstract: Interconnect systems and method of operating such are disclosed. A plurality of nodes coupled via a packet transport path form an interconnect and the nodes provide ingress points to the interconnect for a plurality of packet sources. A central controller holds permitted rate indications for each of the plurality of packet sources, in accordance with which each packet source sends packets via the interconnect. The nodes each respond to packet collision event at that node by sending a collision report to the central controller. In response the central controller, in respect of a collision pair of packet sources associated with the packet collision, decreases the permitted rate indication corresponding to a packet source of the collision pair of packet sources which currently has the higher permitted rate indication. Periodically the permitted rate indications of all of the packet sources are increased, subject to a maximum permitted rate indication for each.

Abstract: The invention relates to a new method of determining in a sample the presence or absence of one or more analyte members of a group of two or more analytes. The invention therefore relates to a multiplex assay for determining the presence or absence of each analyte in a group of multiple analytes. The assay uses aptamers and transmembrane pores.

Abstract: The invention relates to a new method of delivering an analyte to a transmembrane pore in a membrane. The method involves the use of microparticles.

Abstract: The disclosed embodiments relate generally to herbal smoking blends and methods for preparing and using herbal smoking blends. Some embodiments relate to a method of preparing an herbal smoking blend, comprising providing a smoking herb preparation comprising cannabis, providing a terpenoid solution comprising at least one terpenoid, providing one or more mercaptans or one or more flavonoids, and adding the terpenoid solution and adding the one or more mercaptans or the one or more flavonoids to the smoking herb preparation. Other embodiments are also included within the scope of the invention.

Abstract: A composition comprising novel coated bulking agent particles for reduction of calories in fat-based food products comprising sugar. A coated bulking agent particle comprising from 2 wt % to 70 wt % bulking agent and from 30 wt % to 98 wt % coating composition comprising sugar and surface active agent; wherein the ratio of sugar to surface active agent in the composition is from 2000:1 to 4:1 and from 50 wt % to 100 wt % of the sugar is in crystalline form; wherein the bulking agent is coated with the coating composition, and, wherein the bulking agent is selected from the group consisting of exhausted cocoa powder, washed coffee powder, washed tea powder, cocoa-shell, wheat bran, corn bran, corn-cob fibre, rice bran, bamboo fibre, coconut fibre, potato fibre, apple fibre, and mixtures thereof; an agglomerated coated bulking agent particle; a process of preparing the particles and a fat-based confection N composition comprising the coated bulking agent particles.

Abstract: Novel coated bulking agent particles for reduction of calories in fat-based food products comprising sugar. A coated bulking agent particle comprising from 2 wt % to 70 wt % bulking agent and from 30 wt % to 98 wt % coating composition comprising sugar and surface active agent; wherein the ratio of sugar to surface active agent in the composition is from 2000:1 to 4:1 and from 50 wt % to 100 wt % of the sugar is in crystalline form; wherein the bulking agent is coated with the coating composition; an agglomerated coated bulking agent particle; a process of preparing the particles and a fat-based confection composition comprising the coated bulking agent particles.

Abstract: An apparatus and method for operating a ring interconnect are disclosed. The ring interconnect has a plurality of nodes that are used to connect to associated components, and is arranged to transport a plurality of slots around the ring interconnect between the nodes in order to transfer items of traffic allocated into those slots between components connected to the nodes. For each item of traffic, one of the components acts as a source to allocate that item of traffic into a slot, and another components acts as destination to seek to remove that item of traffic from the slot. In a default mode of operation, the ring interconnect is arranged to allow all of the slots to be available for transfer of any items of traffic.