Abstract: The present disclosure provides compounds of Formula I, useful for the activation of Triggering Receptor Expressed on Myeloid Cells 2 (“TREM2”). This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a neurodegenerative disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.

Abstract: This disclosure relates to a medical image viewer for incorporating multi-user collaboration features, such as in-image commenting and workspace sharing. An example method includes receiving a comment location including image coordinates and comment information associated with the comment from a user device. The comment information includes a text body, identify identity information related to the user, and a comment creation date. The example method further includes determining world coordinates based on the image coordinates, and storing the world coordinates and the comment information as a subset of header attributes of the DICOM image file.

Abstract: Embodiments for a networking device are disclosed. The networking device includes a private identity-based cryptographic (IBC) key issued for a first device. The networking device can receive an internet protocol (IP) packet from the first device. The networking device modifies the IP packet to form a modified IP packet, wherein modify the IP packet includes add an extension header to the IP packet. The extension header includes a source identifier identifying the first device, an indication of the key generation authority and an indication of an identity-based encryption (IBE) algorithm. The networking device also generates an identity-based signature (IBS) using the IBC algorithm with the source identifier as an identity input, the modified IP packet as a message input, and the private IBC key for the first device as a private key input. The modified IP packet and the IBS is then sent towards a destination of the IP packet.

Abstract: Embodiments of the disclosure provide a system for analyzing noise data for light detection and ranging (LiDAR). The system includes a communication interface configured to sequentially receive noise data of the LiDAR in time windows, at least one storage device configured to store instructions, and at least one processor configured to execute the instructions to perform operations. Exemplary operations include determining an estimated noise value of a first time window using the noise data received in the first time window and determining an instant noise value of a second time window using the noise data received in the second time window. The second time window is immediately subsequent to the first time window. The operations also include determining an estimated noise value of the second time window by aggregating the estimated noise value of the first time window and the instant noise value of the second time window.

Abstract: A computing system includes a host device and a root of trust (RoT) device for performing batch encryption and decryption operations facilitated by a direct memory access (DMA) engine. The host device generates a command table for batch processing of a set of address tables that each describe a set of data blocks of a file to be encrypted or decrypted. The DMA engine facilitates a DMA transfer of the command table from the host memory to an RoT memory of the RoT device. The RoT device then performs batch processing of the address tables referenced in the command table. For each address table, the DMA engine copies a set of data blocks from the host memory to the RoT memory, a cryptographic engine encrypts or decrypts the data blocks, and the DMA engine copies the transformed data blocks back to the host memory.

Abstract: A screen repair patch and a screen flaw repair method. The screen repair patch includes an optical layer, a substrate layer, and an adhesion layer. The optical layer and a screen to be repaired have the same or similar optical performance. The substrate layer has a thickness of 10 to 250 microns. The adhesion layer has a thickness of 5 to 200 microns. In the screen flaw repair method, a repair patch is cut off from a region on a patch sheet corresponding to the position of a flaw of a screen, and the repair patch is attached to the corresponding position of the flaw of the screen by using a joining direction of the screen as an affixing direction of the repair patch.

Abstract: A computing system includes a host device and a root of trust (RoT) device for performing batch encryption and decryption operations facilitated by a direct memory access (DMA) engine. The host device generates a command table for batch processing of a set of address tables that each describe a set of data blocks of a file to be encrypted or decrypted. The DMA engine facilitates a DMA transfer of the command table from the host memory to an RoT memory of the RoT device. The RoT device then performs batch processing of the address tables referenced in the command table. For each address table, the DMA engine copies a set of data blocks from the host memory to the RoT memory, a cryptographic engine encrypts or decrypts the data blocks, and the DMA engine copies the transformed data blocks back to the host memory.

Abstract: A DMA system includes two or more DMA engines that facilitate transfers of data through a shared memory. The DMA engines may operate independently of each other and with different throughputs. A data flow control module controls data flow through the shared memory by tracking status information of data blocks in the shared memory. The data flow control module updates the status information in response to read and write operations to indicate whether each block includes valid data that has not yet been read or if the block has been read and is available for writing. The data flow control module shares the status information with the DMA engines via a side-channel interface to enable the DMA engines to determine which block to write to or read from.

Abstract: Aspects of the present disclosure involve a method and a system to perform the method to obtain a cryptographic output of a plurality of rounds of a cipher, by performing a plurality of modified rounds of the cipher, each of the modified rounds computing an unmasking transform, an operation of a respective round of the cipher, and a masking transform, the unmasking transform being an inverse of the masking transform of a previous round of the cipher.

Abstract: The present invention provides a detection device comprises a testing element and a transparent area, wherein the testing element comprises a detection area which is configured to detect a presence of an analyte in a liquid sample; the transparent area is configured to read the test result on the detection area through the transparent area; a part of the transparent area contacts a part of the detection area, or the detection area and the transparent area are arranged in one sealed space, thus to make the air in the sealed space not exchange with the air outside the sealed space; the scheme can reduce the mist to ensure the test result is displayed clearly.

Abstract: Embodiments of the disclosure provide receivers for a light detection and ranging (LiDAR) scanner. The receiver includes a photodetector configured to receive a laser beam, and convert the received laser beam to an electrical signal including a plurality of pulses. The receiver also includes an amplifier configured to amplify the electrical signal. The receiver further includes a pulse equalizer configured to sharpen the plurality of pulses in the amplified electrical signal. Each pulse is sharpened to have a narrower width and an increased amplitude.

Abstract: A system and method for correcting a Light Detection And Ranging (LiDAR) return signal is disclosed. The LiDAR return signal is digitized by a converter. An exemplary signal correction system includes a signal processor configured to identify saturated samples from the LiDAR return signal, determine a correction parameter based on non-saturated samples in the LiDAR return signal and corresponding samples in a reference signal, and correct the saturated samples in the LiDAR return signal using the correction parameter.

Abstract: The present invention provides a detection device, and the device comprises a testing element, wherein the testing element comprises a detection area used for detecting a presence of an analyte in a liquid sample; and a transparent area through which the test result on the detection area is read, and the transparent area includes a hydrophilic area and a hydrophobic area. Thus, the detection device reduces formation of droplets on the transparent area is reduced, that is, it avoids formation of a mist layer on the transparent area; or avoids accumulation of small droplets on the transparent area, thus to make the result on the test area be clearly read.

Abstract: The present invention discloses a detection apparatus, comprising a base layer, wherein the base layer comprises a groove for containing a testing element and a sample chamber for collecting a fluid sample. The detection apparatus can achieve fast, efficient and accurate detection of analytes in liquid samples, make operators to perform testing conveniently and freely, without causing incorrect results. In some preferred modes, the sample chamber comprises a liquid channel.

Abstract: A magnetic electric connector and its magnetic terminal. The magnetic electric connector comprises a male connector and a receptacle which are adapted to each other. The male connector comprises an insulator and several first magnetic terminals. The first magnetic terminal comprises a first magnet and a first metallic conducting layer fixed to the outer surface of the first magnet. The receptacle comprises a bench insulator and several second magnetic terminals. The second magnetic terminal comprises a second magnet and a second metallic conducting layer fixed to the outer surface of the second magnet. When the male connector and receptacle are butted, the first magnetic terminal of male connector is adsorbed on the second magnetic terminal of receptacle, forming electrical conduction, implementing charging or transmitting data, they can be localized and fastened without an additional fixing structure, guaranteeing a stable butting of male connector and receptacle.