Abstract: A method of producing a conductive nanoporous support, comprises: (i) producing an inorganic template by mixing and subjecting to high-energy ball milling an inorganic material and a powder selected from a carbonaceous material, a polymer, or a metal oxide; and (ii) coating the inorganic template with metal nanoparticles to obtain the nanoporous support. The invention further relates to a conductive nanoporous support, an electrolytic electrode, or gas diffusion electrode and an electrolytic cell or fuel cell.

Abstract: In various examples, sensor data representative of an image of a field of view of a vehicle sensor may be received and the sensor data may be applied to a machine learning model. The machine learning model may compute a segmentation mask representative of portions of the image corresponding to lane markings of the driving surface of the vehicle. Analysis of the segmentation mask may be performed to determine lane marking types, and lane boundaries may be generated by performing curve fitting on the lane markings corresponding to each of the lane marking types. The data representative of the lane boundaries may then be sent to a component of the vehicle for use in navigating the vehicle through the driving surface.

Abstract: Rather than typical slot type games where specific matching combinations of symbols along paylines through a row-by-column grid or matrix indicate the outcome of the game, a slot type concatenation game concatenates value symbols along a payline to form a numerical outcome. Non-value symbols may be omitted and/or ignored. Further, the payline may be indicated by the presence of a trigger symbol, which may allow the payline to change between different plays of the slot type concatenation game. Further, the slot type concatenation game may be user-configurable. Users may be allowed to indicate the number of the symbol reels that may include value symbols that will be concatenated along a payline defined by the trigger symbol. Users may be allowed indicate the denomination set that is used to configure the symbol reels with value symbols, such as from one or more value symbol tables.

Abstract: The present invention relates to methods of preparing a therapeutic exosome using a protein newly-identified to be enriched on the surface of exosomes. Specifically, the present invention provides methods of using the proteins for affinity purification of exosomes. It also provides methods of localizing a therapeutic peptide on exosomes, and targeting exosomes to a specific organ, tissue or cell by using the proteins. The methods involve generation of surface-engineered exosomes that include one or more of the exosome proteins at higher density, or a variant or a fragment of the exosome protein.

Abstract: The present application relates to azaaromatic amide derivatives for the treatment of cancer. Specifically, the present application relates to a preparation method and use of azaaromatic amide derivatives. The present application relates to azaaromatic amide derivatives and anilino-pyrimidine compounds represented by formula (I), formula (II), formula (III), formula (IV), and formula (V), and pharmaceutically acceptable salts thereof; the compounds or salts thereof can be used to treat or prevent a disease or disorder by regulating certain mutant forms of epidermal growth factor receptors. The present application also relates to a pharmaceutical composition comprising the compounds or salts thereof, and a method for treating various diseases mediated by EGFR, or HER2, or HER4 by using the compounds and salts thereof.

Abstract: This disclosure relates to cathode active materials for use in lithium-ion battery cells.

Abstract: This disclosure relates generally to battery cells, and more particularly, cathode active materials for use in lithium-ion battery cells.

Abstract: On or more examples relate, generally, to an apparatus that includes a reconciliation sublayer of a physical layer, a reduced media independent interface (RMII) of the physical layer, and a logic circuit. Such a logic circuit may operate to receive a changed carrier sense signal provided by the reconciliation sublayer, generate a further changed carrier sense signal at least partially responsive to a prediction that the changed carrier sense signal would cause unintended signaling at the RMII, and provide the further changed carrier sense signal to the RMII.

Abstract: Provided are compounds of Formula (I): wherein R1, R2, X, Ring A, Ring B, and Ring C are as defined herein. Compounds of Formula (I) are useful as inhibitors of DNA-PK. Also provided are pharmaceutical compositions comprising said compounds and methods of using the compounds and compositions in the treatment of various diseases, conditions, and disorders.

Abstract: A method includes obtaining a blended red-green-blue (RGB) image frame of a scene. The method also includes performing, using at least one processing device of an electronic device, an interband denoising operation to remove at least one of noise and one or more artifacts from the blended RGB image frame in order to produce a denoised RGB image frame. Performing the interband denoising operation includes performing filtering of red, green, and blue color channels of the blended RGB image frame to remove at least one of the noise and the one or more artifacts from the blended RGB image frame. The filtering of the red and blue color channels of the blended RGB image frame is based on image data of at least one of the green color channel and a white color channel of the blended RGB image frame.

Abstract: Methods of making such compounds, powders, and cathode active materials are described. The powders are formed of particles with specific properties: a particle size distribution with a D50 ranging from 10 ?m to 20 ?m, a D10 less than 8 ?m, and a D99 of the particles ranges from 25 ?m to 35 ?m. The final compound is represented by the Formula Li?(Co1-x-y-zMnxMezAly)O?, wherein 0.95<?<1.05, x?1.00, 0<y?0.04, 0<z?0.050, and ??2.

Abstract: A device (100;120;140) and method (600) for storing encryption keys are provided. The device comprises: a first connector for connection to a computer, an internal memory (104); an input module (101); and an authentication module (103) for receiving user identification information, via the input module, from a user. The authentication module is configured to check received user identification information against stored user identification information stored on the internal memory to determine if a user is a valid user. A first data encryption key, DEK, is stored in encrypted form on the internal memory and is associated with the stored user identification information of a first plurality of user identities, and a second DEK is stored in encrypted form on the internal memory and is associated with the stored user identification information of a second, different, plurality of user identities.

Abstract: A component of a plasma processing chamber having at least one plasma facing surface of the component comprises single crystal metal oxide material. The component can be machined from a single crystal metal oxide ingot. Suitable single crystal metal oxides include spinel, yttrium oxide, and yttrium aluminum garnet (YAG). A single crystal metal oxide can be machined to form a gas injector of a plasma processing chamber.

Abstract: The present disclosure relates to compounds, compositions, and methods for the treatment of primary hyperoxaluria type 1 and recurrent kidney stone formers. The present disclosure is directed to novel substituted heterocyclic carboxylate compounds and methods for their preparation and use as therapeutic or prophylactic agents. In particular, the present disclosure provides novel inhibitors of human glycolate oxidase enzyme, pharmaceutical compositions containing such compounds, and methods for using these compounds to treat primary hyperoxaluria type 1 and recurrent kidney stone formers.

Abstract: A method of plating substrates may include placing a substrate in a plating chamber comprising a liquid, and applying a current to the liquid in the plating chamber to deposit a metal on exposed portions of the substrate, where the current may include alternating cycles of a forward plating current and a reverse deplating current. To determine the current characteristics, a model of a substrate may be simulated during the plating process to generate data points that relate characteristics of the plating process and a pattern on the substrate to a range nonuniformity of material formed on the substrate during the plating process. Using information from the data points, values for the forward and reverse currents may be derived and provided to the plating chamber to execute the plating process.

Abstract: Microelectronic devices include a stack structure of insulative structures vertically alternating with conductive structures and arranged in tiers forming opposing staircase structures. A polysilicon fill material substantially fills an opening (e.g., a high-aspect-ratio opening) between the opposing staircase structures. The polysilicon fill material may have non-compressive stress such that the stack structure may be partitioned into blocks without the blocks bending and without contacts—formed in at least one of the polysilicon fill material and the stack structure—deforming, misaligning, or forming electrical shorts with neighboring contacts.

Abstract: Compounds, particles, and cathode active materials that can be used in lithium ion batteries are described herein. Methods of making such compounds, powders, and cathode active materials are described. The particles have a particle size distribution with a D50 ranging from 10 ?m to 20 ?m.

Abstract: Rather than typical slot type games where specific matching combinations of symbols along paylines through a row-by-column grid or matrix indicate the outcome of the game, a slot type concatenation game concatenates value symbols along a payline to form a numerical outcome. Non-value symbols may be omitted and/or ignored. Further, the payline may be indicated by the presence of a trigger symbol, which may allow the payline to change between different plays of the slot type concatenation game. Further, the slot type concatenation game may be user-configurable. Users may be allowed to indicate the number of the symbol reels that may include value symbols that will be concatenated along a payline defined by the trigger symbol. Users may be allowed indicate the denomination set that is used to configure the symbol reels with value symbols, such as from one or more value symbol tables.

Abstract: Compositions and methods for development of potent siRNA therapeutics for prevention and treatment of Corona Virus (2019-nCoV; COVID-19) infections are provided. The compositions include a pharmaceutical composition comprising siRNA cocktails that target critical viral genes and pharmaceutically acceptable polymeric nanoparticle carriers and liposomal nanoparticle carriers. Administration methods for prevention and treatment are provided, including airway instillation, subcutaneous injections and nebulizer aerosolization.

Abstract: The techniques of the present disclosure provide a method of inhibiting tumor growth in a tissue of a mammal. The method includes administering to the mammal a therapeutically effective amount of a composition comprising an siRNA molecule that binds to an mRNA that codes for TGF?1 protein, an siRNA molecule that binds to an mRNA that codes for VEGFR2 protein, and a pharmaceutically acceptable carrier comprising a pharmaceutically acceptable polypeptide polymer. The techniques of the present disclosure also provide for additional methods for using this composition.