Abstract: A method is described for detecting lung cancer comprising detecting an elevated level of a CTAP III-related biomarker in a biological sample from a subject at risk for developing lung cancer. Further, a method is described for predicting risk of developing lung cancer in a subject comprising detecting an elevated level of a CTAP III-related biomarker in a biological sample from a subject. Additionally, a method of monitoring the success of lung cancer treatment with curative intent is described comprising detecting levels of a CTAP III-related biomarker in a biological sample from a subject undergoing treatment for lung cancer for comparison with the a previous level obtained from the subject. Multivariate analysis may be incorporated into these methods, evaluating such clinical, or demographic risk factors as age, sex, smoking history, smoking status, smoking family history, education level, COPD, socio-economic status, body mass index and lung function. Kits for conducting such methods are described.

Abstract: A method of reconfiguring a multi-wavelength communication network. The transition includes determining the union of the old and new topologies. During at least the start of the transition, the network supports the union topology. New connections are connected according to the new topology, and the old topology, as its connections expire, is gradually removed. In allocating wavelengths to a new topology, two algorithms are developed which assign wavelengths which do not color clash with the wavelength assignments of the old topology.