Abstract: The present invention relates to a method of analyzing a blood sample of a subject for the presence of a disease marker, said method comprising the steps of a) extracting nucleic acid from anucleated blood cells in said blood sample to provide an anucleated blood cells-extracted nucleic acid fraction, and b) analysing said anucleated blood cells-extracted nucleic acid fraction for the presence of a disease marker, wherein said disease marker is a disease-specific mutation in a gene of a cell of said subject, or wherein said disease marker is a disease-specific expression profile of genes of a cell of said subject.

Abstract: A processing device (60) for a radio-receiver circuit (20) is disclosed. The radio-receiver circuit comprises an input terminal (22) for receiving an analog input signal, circuitry (50) for generating a compensated analog input signal by subtracting an analog compensation signal from the analog input signal, an analog-to-digital converter (30) arranged to receive the compensated analog input signal on an input terminal of the analog-to-digital converter (30), and circuitry (40, 110) for to generating the analog compensation signal based on a digital compensation signal. The processing device (60) comprises: an input terminal (62) for receiving an output signal of the analog-to-digital converter (30); and an output terminal (64) for supplying the digital compensation signal.

Abstract: A system and an operating method are provided for supporting lane keeping of a vehicle equipped with a steering device. The system and operating method include providing vehicle related information; providing environment related information; combining vehicle and environment related information; predicting a future trajectory of the vehicle based on vehicle and environment related information; estimating a desired lateral lane position of the vehicle and/or a guiding force; comparing the future trajectory and the desired lateral lane position; deciding if a guiding force is to be provided to the steering device; and, if guiding force is to be provided, defining an amount of said guiding force depending on a hierarchically ordered set describing a predetermined driving behavior of the vehicle, adapting the amount of guiding force depending on the direction in which the vehicle is intended to move and activating one or more actuators for supplying the adapted amount of guiding force to the steering device.

Abstract: There is provided a process for the preparation of a compound of formula I, wherein X, R1, R2a, R2b, R2c, R2d, R2e, R3a, R3b, R3c, R3d and R3e are as described in the description. Such compounds may, for example, be useful medicament (or intermediates for medicaments).

Abstract: In a method for reducing engine vibrations during engine braking with a malfunctioning engine brake, the engine brake includes an arrangement for altering a timing of at least one exhaust valve and an arrangement for varying an exhaust gas back pressure. The method includes detecting piston acceleration for each cylinder in the engine during the use of the engine brake, comparing the detected piston acceleration with a predetermined reference value, decreasing exhaust gas back pressure during engine braking if at least one piston is detected with a piston acceleration deviating more than a predefined amount from the predetermined reference value so that the piston acceleration will be falling within the predefined amount from the predetermined reference value.

Abstract: A filling assembly for filling of a tube of packaging material having a seal starting at a first level, comprises a conduit arranged to lead liquid into the tube of packaging material below said first level and a passage arranged to eject gas through openings into the tube of packaging material below said first level. The filling assembly is characterized in that a gasket is arranged to provide a seal between said filling assembly and said tube of packaging material upstream said openings such that the overpressure P1 downstream the gasket may exceed an ambient pressure Pa upstream the gasket.

Abstract: A processing device (60) for a radio-receiver circuit (20) is disclosed. The radio-receiver circuit comprises an input terminal (22) for receiving an analog input signal, circuitry (50) for generating a compensated analog input signal by subtracting an analog compensation signal from the analog input signal, an analog-to-digital converter (30) arranged to receive the compensated analog input signal on an input terminal of the analog-to-digital converter (30), and circuitry (40, 110) for to generating the analog compensation signal based on a digital compensation signal. The processing device (60) comprises: an input terminal (62) for receiving an output signal of the analog-to-digital converter (30); and an output terminal (64) for supplying the digital compensation signal.

Abstract: In a method for reducing engine vibrations during engine braking with a malfunctioning engine brake, the engine brake includes an arrangement for altering a timing of at least one exhaust valve and an arrangement for varying an exhaust gas back pressure. The method includes detecting piston acceleration for each cylinder in the engine during the use of the engine brake, comparing the detected piston acceleration with a predetermined reference value, decreasing exhaust gas back pressure during engine braking if at least one piston is detected with a piston acceleration deviating more than a predefined amount from the predetermined reference value so that the piston acceleration will be falling within the predefined amount from the predetermined reference value.

Abstract: A system and an operating method are provided for supporting lane keeping of a vehicle equipped with a steering device. The system and operating method include providing vehicle related information; providing environment related information; combining vehicle and environment related information; predicting a future trajectory of the vehicle based on vehicle and environment related information; estimating a desired lateral lane position of the vehicle and/or a guiding force; comparing the future trajectory and the desired lateral lane position; deciding if a guiding force is to be provided to the steering device; and, if guiding force is to be provided, defining an amount of said guiding force depending on a hierarchically ordered set describing a predetermined driving behavior of the vehicle, adapting the amount of guiding force depending on the direction in which the vehicle is intended to move and activating one or more actuators for supplying the adapted amount of guiding force to the steering device.

Abstract: The present invention relates to an antenna assembly comprising a support structure for carrying a radiating structure and at least one feeding clip, the antenna assembly is provided to be mounted on a PCB in a mobile communication device, the support structure comprises a top side part which is to be mounted substantially parallel with the PCB, the top side part is positioned, when mounted on the PCB, at a first distance from the PCB, and the radiating structure comprises at least one contact area located on the support structure. The antenna assembly is characterised in that the contact area for the radiating structure is located at a position on the support structure where a distance between the contact area and the PCB is less than the distance between said top side part and the PCB. The invention also relates to a feeding clip.

Abstract: A method of determining the velocity (?) of a vehicle is provided. The vehicle has at least one pair of a front and a rear wheel which are spaced by a wheel spacing (B). Front and rear wheel speed signals (?) are determined which are indicative of the time dependent behavior of the front and rear wheel speeds, respectively. The front and rear wheel speed signals (?) are correlated in order to determine a specific correlation feature indicative of the time delay (?) between the front wheel and rear wheel speed signals. The velocity (?) of the vehicle is determined based on the correlation feature and the wheel spacing (B).

Abstract: The invention relates to compounds of the general formula (I): wherein Ar is optionally substituted aryl or heteroaryl; A is (i) —O—, —S—, —SO2—, —NH—, (ii) a C1-4-alkyl- or C1-6-acyl-substituted nitrogen atom or (iii) a C1-8-alkylene chain or a heteroalkylene chain having 2 to 8 chain atoms, which optionally contains at least one unsaturation, and which may be substituted and/or contain a bridge to form a saturated or partially or fully unsaturated ring having 3-8 ring members; B is —C(R4)(R5)—, —OC(R4)(R5)—, —N(R6)C(R4)(R5)—, —N(R6)—, —O—, —S— or —SO2—; R is optionally substituted C3-8-cycloalkyl, aryl or heteroaryl; R1 is (i) a saturated or unsaturated azacyclic or aminoazacyclic ring, or a saturated diazacyclic or aminodiazacyclic ring, which has 4 to 7 ring members, or a saturated aminoazabicyclic, azabicyclic or diazabicyclic ring which has 7 to 10 ring members, which rings optionally are substituted in one or more positions, or a group —[C(R4)(R5)]xN(R2a)(R3a)]; R2a, R3a, R4, R5, R6 and x are as

Abstract: The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts thereof, which are useful as inhibitors of human stearoyl-CoA desaturase (SCD). The invention further relates to pharmaceutical compositions comprising these compounds and to the use of these compounds for the treatment or prevention of medical conditions in which the modulation of SCD activity is beneficial, such as cardiovascular diseases, obesity, non-insulin-dependent diabetes mellitus, hypertension, metabolic syndrome, neurological diseases, immune disorders, cancer and various skin diseases.

Abstract: The present invention relates to compounds of the formula (I): including pharmaceutically acceptable salts, solvates, hydrates, geometrical isomers, tautomers, optical isomers, and N-oxides thereof, said compounds being useful as inhibitors of stearoyl-CoA desaturase (SCD). The invention further relates to the use of compounds of the formula (I) for treatment of medical conditions in which the modulation of SCD activity is beneficial, such as cardiovascular diseases, obesity, non-insulin-dependent diabetes mellitus, hypertension, neurological diseases, immune disorders, cancer, essential fatty acid deficiency, acne, psoriasis, rosacea or other skin conditions.

Abstract: The invention relates to a steel alloy of the following composition (in % by weight) C 0.40-0.60 Si 0.1-1.0 Mn 0.3-1.0 Cr 12-15 MO 2.5-4.0 Ni 0-1.0 Co 0-4.0 N 0.15-0.20, with the balance Fe as well as normally occurring impurities, the hardness being >56 HRC, which has been attained without deep freezing, as well as PRE>25, defined as PRE=% Cr+3.3•% Mo+16•% N. Furthermore, the steel alloy comprises carbides, nitrides and/or carbonitrides the maximal diameter of which does not exceed 5 ?m. This steel alloy has turned out surprisingly well suitable as edge material for a plurality of cutting operations.

Abstract: The present invention relates to an antenna assembly comprising a support structure for carrying a radiating structure and at least one feeding clip, the antenna assembly is provided to be mounted on a PCB in a mobile communication device, the support structure comprises a top side part which is to be mounted substantially parallel with the PCB, the top side part is positioned, when mounted on the PCB, at a first distance from the PCB, and the radiating structure comprises at least one contact area located on the support structure. The antenna assembly is characterised in that the contact area for the radiating structure is located at a position on the support structure where a distance between the contact area and the PCB is less than the distance between said top side part and the PCB. The invention also relates to a feeding clip.

Abstract: The invention relates to compounds of the general formula (I): wherein Ar is optionally substituted aryl or heteroaryl; A is (i) —O—, —S—, —SO2—, —NH—, (ii) a C1-4-alkyl- or C1-6-acyl-substituted nitrogen atom or (iii) a C1-8-alkylene chain or a heteroalkylene chain having 2 to 8 chain atoms, which optionally contains at least one unsaturation, and which may be substituted and/or contain a bridge to form a saturated or partially or fully unsaturated ring having 3-8 ring members; B is —C(R4)(R5)—, —OC(R4)(R5)—, —N(R6)C(R4)(R5)—, —N(R6)—, —O—, —S— or —SO2—; R is optionally substituted C3-8-cycloalkyl, aryl or heteroaryl; R1 is (i) a saturated or unsaturated azacyclic or aminoazacyclic ring, or a saturated diazacyclic or aminodiazacyclic ring, which has 4 to 7 ring members, or a saturated aminoazabicyclic, azabicyclic or diazabicyclic ring which has 7 to 10 ring members, which rings optionally are substituted in one or more positions, or a group —[C(R4)(R5)]xN(R2a)(R3a)]; R2a, R3a, R4, R5, R6 and x are as

Abstract: The invention relates to compounds of the general formula (I) wherein R0, R1, R2, R3, R4, R5, R6, R7, R8, R9, Ar, and X are as defined in the description, or a pharmaceutically acceptable salt, hydrates, geometrical isomers, racemates, tautomers, optical isomers, N-oxides and prodrug forms thereof. The compounds may be used for the treatment or prophylaxis of disorders related to the MCH1R receptor and for modulation of appetite. The invention also relates to such use as well as to pharmaceutical formulations comprising a compound of formula (I).

Abstract: In a method for checking fingerprints, reference partial areas are compared with slightly larger current partial areas in different relative positions. The comparison between a reference partial area and a current partial area begins with the reference partial area centered in relation to the current partial area. Thereafter, the reference partial area is moved in stages in a spiral shape out towards the edges of the current partial area. As soon as a relative is found for which a predetermined requirement of likeness is satisfied, the reference partial area is considered to match the current partial area and the comparison is interrupted. As soon as a predetermined number of matching reference partial areas have been found, the checked fingerprint is approved and the check is terminated. The check can be carried out in two phases with different sizes of reference partial areas. The method has the advantage of being so rapid that it can be carried out on a JAVA smart card in reasonable time.

Abstract: The invention relates to compounds of the general formula (I): 1