Abstract: A device is provided that humidifies breathing gas. The device has a chamber with an inlet and an outlet. A chemical heater is positioned within the chamber and a trigger activates the heater. The chamber can be a conduit with an inner wall and an outer wall with a reservoir defined therebetween. The chemical heater can be positioned within the reservoir.

Abstract: A person support apparatus, such as a bed, stretcher, cot, recliner, or the like, includes an exit detection system having a plurality of force sensors that support the weight of an occupant positioned on a support surface. The force sensors are part of an exit detection system that issues an alarm when the occupant exits, or is about to exit, the person support apparatus. The distribution of weight applied to the force sensors is used to determine if the occupant is about to exit the person support apparatus. Compensation is made to the exit detection system for changes in the weight distribution that are not caused by movement of the occupant. Such changes may be due to siderail movement, support surface pivoting, and/or movement of other components of the person support apparatus.

Abstract: The present disclosure relates to a portable Raman probe that uses axicon lenses (“axicons”), grating axicons (“graxicons”), and other optical elements to collect spectra from substances behind non-opaque barriers using off-axis techniques. The portable Raman probe can also include a Raman spectrometer to analyze the collected spectra, and a spectra refinement machine-learning model to generate refined spectra from raw or noisy collected samples.

Abstract: The present disclosure relates to a portable Raman probe that uses axicon lenses (“axicons”), grating axicons (“graxicons”), and other optical elements to collect spectra from substances behind non-opaque barriers using off-axis techniques. The portable Raman probe can also include a Raman spectrometer to analyze the collected spectra, and a spectra refinement machine-learning model to generate refined spectra from raw or noisy collected samples.

Abstract: The present disclosure relates to a portable Raman probe that uses axicon lenses (“axicons”), grating axicons (“graxicons”), and other optical elements to collect spectra from substances behind non-opaque barriers using off-axis techniques. The portable Raman probe can also include a Raman spectrometer to analyze the collected spectra, and a spectra refinement machine-learning model to generate refined spectra from raw or noisy collected samples.

Abstract: Presented herein are methods and compositions for concatenating template strands during the bridge amplification process. The methods are useful for surface amplification at improved densities. The methods and compositions provided herein enable creation of clusters that are brighter, but at the same densities as currently achieved using standard cluster amplification.

Abstract: In some embodiments, a humidification system includes a heater base having a heater plate, a humidification chamber, and circuit. The circuit can include various conduits, including an inspiratory conduit, expiratory conduit, Y-piece, patient conduit, and/or dry conduit. In use, the chamber contains a quantity of liquid. The heater base heats the heater plate, which in turn heats the liquid to a temperature that causes at least some of the liquid to become vapor, thereby humidifying the gases within the chamber. The gas is delivered to the patient via the inspiratory conduit. Various features can help control the system and ensure the patient receives gases having the desired conditions. These features can be used individually or in various combinations and subcombinations both in existing humidification systems and improved systems for respiratory humidification, laparoscopy, and other purposes.

Abstract: A vehicle interaction system to allow passenger interaction with a public transport vehicle, the system including a processing system, a passenger client device configured to: determine a selected vehicle stop in accordance with user input commands; provide a selected vehicle stop to the processing system; and, notify the passenger when the vehicle is approaching the selected vehicle stop and a vehicle terminal configured to: receive a selected vehicle stop notification from the processing system; determine when the vehicle is approaching the selected stop by monitoring a current vehicle location; and, in response to a positive determination, selectively controlling at least part of the operation of the vehicle and/or alert the driver.

Abstract: Patient support apparatuses, such as beds, cots, stretchers, recliners, operating tables, and the like include wireless mesh network transceivers that enable them to communicate with each other, and other devices, via mesh networks and/or ad hoc networks. One or more additional wireless transceivers are included, such as WiFi transceivers that enable direct communication with a healthcare facility network, such as an Ethernet. The mesh network communication between patient support apparatuses and other devices is used for any one or more of: extending the communication range of the existing IT infrastructure, efficiently routing data to the healthcare facility network, determining location of the patient support apparatuses and devices, transporting patient data from one patient support to the next as the patient moves, and for other aspects.

Abstract: The present invention relates to a compound of the Formula: or a pharmaceutically acceptable salt thereof. The compound of the present invention inhibits Pol?. This novel therapeutic compound is therefore useful for the treatment and/or prevention of diseases and conditions in which Pol? activity is implicated, such as, for example but not limited to, the treatment and/or prevention of cancer. The present invention also relates to pharmaceutical compositions comprising the novel therapeutic compound defined herein, to processes for synthesising the compound and to their use for the treatment of diseases and/or conditions in which Pol? activity is implicated.

Abstract: The present invention relates to a compound of the Formula: or a pharmaceutically acceptable salt thereof. The compound of the present invention inhibits Pol?. This novel therapeutic compound is therefore useful for the treatment and/or prevention of diseases and conditions in which Pol? activity is implicated, such as, for example but not limited to, the treatment and/or prevention of cancer. The present invention also relates to pharmaceutical compositions comprising the novel therapeutic compound defined herein, to processes for synthesising the compound and to their use for the treatment of diseases and/or conditions in which Pol? activity is implicated.

Abstract: The present invention relates to a compound of the Formula: or a pharmaceutically acceptable salt thereof. The compound of the present invention inhibits Pol?. This novel therapeutic compound is therefore useful for the treatment and/or prevention of diseases and conditions in which Pol? activity is implicated, such as, for example but not limited to, the treatment and/or prevention of cancer. The present invention also relates to pharmaceutical compositions comprising the novel therapeutic compound defined herein, to processes for synthesising the compound and to their use for the treatment of diseases and/or conditions in which Pol? activity is implicated.

Abstract: A device for monitoring an environment is disclosed. The device comprises a processor configured to: receive input from one or more sensors, which together are associated with a plurality of locations in the environment; based on the input: detect an object at a first time, and output a first instruction for outputting a first deterrent; and determine whether a predetermined condition is met with respect to one or more of: a location of the object at a later time or a direction of travel of the object at a later time; and if the predetermined condition is met, output a second instruction to another device, the second instruction being associated with a process for outputting a second deterrent.

Abstract: A method for aligning a tree within a resource extraction system includes disposing a riser system on a wellhead of the resource extraction system without utilizing a mechanical alignment system to circumferentially align the riser system with the wellhead. The method also includes disposing a tubing hanger at a landed position within the wellhead. In addition, the method includes disposing an orientation mechanism on the wellhead. The orientation mechanism includes an alignment feature configured to engage a corresponding alignment feature of the tree. Furthermore, the method includes moving the tree toward the wellhead such that the alignment feature of the tree engages the alignment feature of the orientation mechanism to approximately establish a target circumferential orientation of the tree relative to the tubing hanger.

Abstract: A respiratory mask system includes a mask interface and a headgear assembly. The headgear assembly is adjustable and comprised of an elastic portion, a non-elastic portion and a restriction mechanism configured to provide a force resisting movement of the non-elastic portion when the elastic portion is extended. There is a support beam coupled to the non-elastic portion and extending along a portion of the headgear that is curved along its longitudinal extent. In this way particular seal modules can be comfortably fitted to a user and any blow off force is mitigated. A particular example of the respiratory mask system includes provision for removable attachment between the seal and a mask frame, the mask frame and a yoke of the headgear; and between a conduit and the mask frame.

Abstract: Flavored flatbread is made by a method comprising providing a cooked flatbread having first and second major surfaces and a thickness of from about 1.0 to about 10 mm and a density of from about 0.1 to about 0.5 g per cubic cm and docking the cooked flatbread to impart a plurality of holes into at least the first major surface of the cooked flatbread. An egg containing liquid mixture is applied to the docked cooked flatbread in an amount and time sufficient to take up from about 0.02 to about 0.09 g per square cm linear surface area of the docked cooked flatbread to provide a coated flatbread. The coated flatbread is cooked to provide a cooked flavored flatbread. Flavored flatbreads are also described.

Abstract: The invention relates to methods of detecting modified cytosines in nucleic acid sequences.

Abstract: Embodiments relate to a device for mounting on a wall for monitoring an environment. In one embodiment the device comprises: a body comprising: an active reflected wave detector; and a processor coupled to the active reflected wave detector, the processor configured to: control the active reflected wave detector to measure wave reflections from the environment to accrue measured wave reflection data, and identify a status of a person in the environment based on the measured wave reflection data, wherein the processor assumes, for said identification, that the active reflected wave detector is at an operating height above a floor of the environment. The device comprises a cord extending from the body, the cord having a length for ending at the floor when the device is mounted with the active reflected wave detector at said operating height and the cord is freely hanging and straight.

Abstract: Aspects of this technical solution can include receiving an order for food, the order including order data, identifying ingredient data and item data from the order data, displaying at least one of a portion of the ingredient data or a portion of the item data on one or more stations configured for preparing the order, where the portion of the ingredient data and the portion of the item data displayed on each of the one or more stations is based on a task to be performed at a respective one of the one or more stations, monitoring the task at each the one or more stations as the task is performed for compliance with the portion of the ingredient data and the portion of the order data displayed at the respective one of the one or more stations, and executing an action based on the monitoring.