Abstract: Provided herein are compositions, systems, and methods for causing weight loss and treating and/or preventing a disease or condition, such as obesity, diabetes, and cancer, with an agent or procedure that inhibits the TMA/FMO3/TMAO pathway in a subject.

Abstract: This invention relates to a breath indicator that is receivable by a part of a breathing assistance apparatus that supplies gas to a patient. The indicator comprises an elongate body having a gas sampling end and an attachment end. The attachment end is adapted to attach to a part of a breathing assistance apparatus and for locating the gas sampling end. The gas sampling end is to be located in a region where gas from the patient is to be exhaled. The gas sampling end being in communication with a sensor comprising a detector material changeable between a first visual indicator state relating to an inhalation phase of the patient, and a second visual indicator state relating to an exhalation phase of the patient. The detector material is capable of changing between the visual indicator states at a sufficient rate to substantially correspond with the inhalation and exhalation phases of the patient.

Abstract: The present disclosure is concerned with compositions and methods for reducing the steps used in the generation of monoclonal clusters by combining the enzymes used for linearization and removal of unused surface primers.

Abstract: A lint brush includes a housing and a lint tool having a lint-removing material. The lint tool is movable along a longitudinal axis of the housing between a stowed position where the lint tool is housed in the housing and a deployed position where the lint tool is extended from the housing. The lint tool is rotatable relative to the longitudinal axis from the deployed position to a first rotated position. An actuator is mounted to one of the housing and the lint tool. The actuator is configured to move the lint tool from the first rotated position back to the deployed position.

Abstract: Techniques and architectures for data ingestion in an environment having a distributed data storage system. A request to import data into the environment. The data to be imported from an external source through an application programming interface (API). The request is analyzed to determine if the request corresponds to a request to import a large data load. The data is staged if the request is for the large data load. Data management jobs are created to cause the data to be stored in one or more nodes of the distributed data storage system. The data management jobs are transmitted to corresponding nodes in the distributed data storage system. The jobs are executed asynchronously to cause the data to be stored in the nodes.

Abstract: An example of a flow cell includes a substrate having depressions separated by interstitial regions. First and second primers are immobilized within the depressions. First transposome complexes are immobilized within the depressions, and the first transposome complexes include a first amplification domain. Second transposome complexes are also immobilized within the depressions, and the second transposome complexes include a second amplification domain. Some of the first transposome complexes, or some of the second transposome complexes, or some of both of the first and second transposome complexes include a modification to reduce tagmentation efficiency.

Abstract: A variety of different types of targeted transposome complexes are described herein that may be used to mediate sequence-specific targeted transposition of nucleic acids.

Abstract: A location detection system identifies the locations of medical devices such as patient support apparatuses and/or patient care devices within a medical facility. The devices communicate via a wired connection to one or more medical facility systems (e.g. nurse call system, computer network, etc.), and/or via a wireless connection to such systems. The location detection system automatically determines location information of the devices and communicates the location information so that the recipient of any outgoing alerts and/or other information sent from the devices is apprised of the location of the particular device sending the alert or other information. Caregivers are thereby able to respond to the correct location of an alert, and software systems such as EMR systems, admission discharge and transfer (ADT) systems, etc. are able to correlate transmitted device data with the location and/or patient assigned to that location.

Abstract: Surgical robotic systems and navigation systems employ a robotic arm including a plurality of links. A link tracker assembly is located on the surface of one or more of the links to enable the link to be tracked by a localizer. The link tracker assemblies can utilize a plurality of tracker elements that can be removably coupled to the link. A photosensor assembly is located on the surface of one or more of the links to receive signals from the localizer for controlling the link tracker assembly. The robotic arm can be coupled to a base and the systems can be used in collaboration with a base tracker that is coupled to the base. The robotic arm can also include a mounting interface for receiving an end effector and the systems can be used in collaboration with an end effector tracker that is coupled to the end effector.

Abstract: Navigation systems, methods and software for assisting in determining whether a tool is properly installed on a surgical device. A protective packaging retains the tool and has a trackable feature. The trackable feature has a predetermined state defined relative to the tool and the trackable feature is detectable by a localizer. One or more controllers acquire the actual state of the tool based on the detected trackable feature and compare the actual state of the tool with an expected state of the tool, which is based on an expected condition in which the tool is properly mounted to the surgical device. Based on the comparison, the one or more controllers can determine whether the tool is properly mounted to the surgical device.

Abstract: A processor that was manufactured by a manufacturer comprises privileged debug operational circuitry, a debug restriction fuse, a credential store, a credential of the manufacturer in the credential store, and debug control circuitry. The debug restriction fuse is a one-time programmable fuse. The debug control circuitry is to automatically restrict access to the privileged debug operational circuitry, based on the debug restriction fuse. The processor may also include public debug operational circuitry, a prevent-unauthorized-debug (PUD) fuse, and an undo-PUD fuse. When the PUD fuse is set and the undo-PUD fuse is clear, the debug control circuitry may respond to an attempt by a debugger to use the public debug operational circuitry by determining whether the debugger is authorized, disallowing access if the debugger is not authorized, and allowing access if the debugger is authorized. Other embodiments are described and claimed.

Abstract: A patient support apparatus includes a plurality of primary sensors adapted to measure different parameters used in the control of the patient support apparatus. One or more suites of secondary sensors are added to the patient support apparatus to provide data about the primary sensors. The secondary sensors may be used to detect errors in the primary sensors, to modify outputs from the primary sensors, and/or to provide usage and/or diagnostic data about the use of the patient support apparatus. The suite(s) of secondary sensors may measure parameters that affect the outputs of one or more of the primary sensors. In some embodiments, the suite(s) of secondary sensors include one or more dormant sensors that are not used on the patient support apparatus until a code modification is received from one or more external sources instructing the control system of the patient support apparatus to begin using the dormant sensor(s).

Abstract: The present disclosure generally relates to golf bags comprising a cord assembly configured to form a plurality of cord dividers that extend across a top opening of the golf bag to define a plurality of compartments for receiving a golf club. The golf bags may comprise a cord connector having a housing with a first channel and a second channel configured to receive one or more segments of the cord assembly. A plurality of cord segments of the cord assembly may extend through each of the first and second channels of the cord connector. The plurality of cord segments may correspond to different cord dividers.

Abstract: An apparatus, method, and system for detecting an object in an environment. The apparatus comprises: a processor configured to: control an active reflected wave detector to measure wave reflections from the environment to accrue measured wave reflection data; process the measured wave reflection data to detect an object in said environment; in response to detection of said object, determine whether a first predetermined condition in respect of the object is met; and if the first predetermined condition is met, control an output device to output a deterrent.

Abstract: Methods of operating electric motor systems that comprise electric motors comprising a rotor having a magnet mounted thereto. The electric motor is initially operated in an open loop mode in which the rotor angle is estimated based on the input voltage frequency. Once the motor is running at sufficient speed, a transition to closed loop mode operation is performed, wherein the rotor angle is determined using an observed back EMF. To provide a smoother open loop to closed loop transition, the rotor angle is determined during a transition period as a function of both the open loop rotor angle and the closed loop rotor angle.

Abstract: An apparatus, method and system for detecting an object in an environment. The apparatus comprises: a processor, the processor coupled to an active reflected wave detector that is operable to measure wave reflections from the environment. The processor is configured to: process measured wave reflection data to determine whether a predetermined condition is met, the measured wave reflection data accrued by the processor in response to the active reflected wave detector being activated in response to a motion sensor detecting motion in said environment; and if the predetermined condition is met, perform at least one operation related to camera image data.

Abstract: Polynucleotide sequencing methods for sequencing one or more polynucleotide templates use primers bound to a surface as sequencing primers. The surface primers may include at least a portion of a surface oligonucleotide used during cluster formation. The sequencing methods may be used for single stranded sequencing or double stranded sequencing. Double stranded sequencing methods may employ an enzyme that has nick-translation activity. A kit includes all the reagents needed for sequencing does not include sequencing primers. The kit may be used to accomplish the sequencing methods of the present disclosure.

Abstract: A zinc-air battery cell assembly comprising: a layer of anode material; one or more layers of cathode material; a separator directly between and engaging both the layer of anode material and the layer of cathode material that acts as both an electronic insulator and an ion conductive path between the layer of anode material and the layer of cathode material; and a diffusion member directly engaging the layer of cathode material.

Abstract: The present disclosure relates to the field of molecular biology and more specifically to microarrays and methods, including methods for modifying immobilized capture primers comprising: a) contacting a substrate comprising a plurality of immobilized capture primers with a plurality of template nucleic acids under conditions sufficient for hybridization to produce one or more immobilized template nucleic acids, and b) extending one or more immobilized capture primers to produce one or more immobilized extension products complementary to the one or more template nucleic acid.

Abstract: Protective packaging, surgical kits, systems, and methods are described herein for assisting in determining whether a tool is properly installed on a surgical device. The protective packaging retains the tool and has trackable features defined relative to a tool center point of the tool. The trackable features have a predetermined state defined relative to the tool center point and the trackable features are configured to be detectable by a localizer to locate the tool center point. One or more controllers can compare the actual state of the tool center point with an expected state of the tool center point, which is based on an expected condition in which the tool is properly mounted to the surgical device. Based on the comparison, the one or more controllers can determine whether the tool is properly mounted to the surgical device.