Abstract: The present invention relates to a system, device, and method for the high throughput multiplexed detection of a wide number of compounds. The invention comprises of a microwell array coupled to a capture agent array to form a plurality of interfaces between a microwell and a set of immobilized capture agents. The set of capture agents comprises a plurality of distinguishable features, with each feature corresponding to the detection of a particular compound of interest. In certain embodiments, each microwell is configured to contain a single cell. The invention is therefore capable of performing a high throughput analysis of single cell profiles, including profiles of secreted compounds.

Abstract: The present document describes devices and methods for rendering multiple live-streams on a user interface (UI) with minimal resources. The UI is activated, having a first set of remote sensors loaded for rendering. The first set of remote sensors receive a first activation signal and begin streaming first data, which the UI renders. Respondent to an action changing the set of remote sensors to be rendered on the UI, a second set of remote sensors are loaded for rendering. The second set of remote sensors receive a second activation signal and begin streaming second data, which the UI renders while the first set of remote sensors continue streaming the first data. The first data is no longer streamed after a threshold time is reached.

Abstract: A method in a computing device includes: monitoring, via a communications interface of the computing device, wireless data elements including application data corresponding to a communications application, and non-application data; automatically generating labels based on the application data of the wireless data elements, the labels indicating performance impacts observable in the communications application; selecting a portion of the wireless data elements corresponding to the non-application data; extracting, from each wireless data element of the non-application data, a set of feature values; generating a plurality of samples from the non-application data, each sample including (i) a number of the sets of feature values based on a sample size, and (ii) one of the automatically generated labels; training a classifier based on the plurality of samples, the classifier configured to receive further non-application data and generate a predicted impact indicator selected from the labels; and deploying the class

Abstract: The present invention provides a system and method for optimizing content to improve search results of a natural language interaction application such as ChatGPT. The method includes processing user data using natural language techniques to identify user intent, sentiment, and other relevant information. The system generates a dynamic response tailored to the specific user and context based on the user's intent, personal profile, and contextual information. The present invention provides a unique approach to optimize content for ChatGPT-based search engines, leading to higher search rankings and increased user engagement. The system also includes local engines that interact with ChatGPT to ensure the accuracy of their classification functions, such as sentiment analysis and tone detection, and machine learning algorithms to improve the system's performance continuously.

Abstract: The present invention relates to a system, device, and method for the high throughput multiplexed detection of a wide number of compounds. The invention comprises of a microwell array coupled to a capture agent array to form a plurality of interfaces between a microwell and a set of immobilized capture agents. The set of capture agents comprises a plurality of distinguishable features, with each feature corresponding to the detection of a particular compound of interest. In certain embodiments, each microwell is configured to contain a single cell. The invention is therefore capable of performing a high throughput analysis of single cell profiles, including profiles of secreted compounds.

Abstract: A computing device comprising: a wireless communications interface configured to connect to a network deployed by a plurality of access points; a controller for the wireless communications interface, the controller configured to: initiate an access point scan to identify nearby access points; during the access point scan: obtain a neighbor report, the neighbor report defining a subset of the plurality of access points and an operating channel for each access point in the subset; select a channel to scan and identify an expected access point operating on the selected channel based on the neighbor report; initiate a channel scan to detect the expected access point on the selected channel; and in response to detecting the expected access point, end the channel scan prior to expiry of a default scan time; and connect to a target access point selected based on the access point scan.

Abstract: Systems and method for wireless roaming include operating, via a wireless communication device, a first communication link between the wireless communication device and a first access point using a first media access control (MAC) layer of the wireless communication device; initiating, using a second MAC layer of the wireless communication device, a roaming handover with a second access point while the first communication link remains configured for transmitting and receiving application and/or IP layer communication packets; ceasing transmission and reception of the application and/or IP layer communication packets via the first communication link after the roaming handover has been initiated; and resuming transmission and reception of the application and/or IP layer communication packets with a second communication link between the wireless communication device and the second access point upon completion of the roaming handover.

Abstract: A method includes: establishing a connection with a wireless network; performing a roam scan to detect a plurality of access points of the wireless network; determining that a first access point of the plurality of detected access points satisfies a signal strength criterion; determining that a second access point of the plurality of detected access points is physically co-located with the first access point; and selecting a roaming destination from the first access point and the second access point.

Abstract: Genetic circuits that control transgene expression in response to pre-defined transcriptional cues would enable the development of smart therapeutics. The present disclosure relates to engineered programmable single-transcript RNA sensors in which adenosine deaminases acting on RNA (ADARs) autocatalytically convert trigger hybridization into a translational output. This system amplifies the signal from editing by endogenous ADAR through a positive feedback loop. Amplification is mediated by the expression of a hyperactive, minimal ADAR variant and its recruitment to the edit site via an orthogonal RNA targeting mechanism. This topology confers high dynamic range, low background, minimal off-target effects, and a small genetic footprint. The circuits and systems disclosed herein leverage an ability to detect single nucleotide polymorphisms and modulate translation in response to endogenous transcript levels in mammalian cells.

Abstract: A computing device includes: a wireless communication interface; and a processor configured to: establish a connection with a wireless network; while a network-layer status of the connection is active, monitor attributes of the connection at the wireless communication interface, the attributes including (i) a number of uplink packets transmitted since a most recent downlink packet was received, and (ii) a time period elapsed since the most recent downlink packet was received; determine that the attributes meet recovery criteria indicative of a network-layer interruption in the wireless network; in response to the determination, control the wireless communication interface to initiate a recovery action to resolve the network-layer interruption.

Abstract: A process for the recovery of gold from carbon fines waste, which are produced, especially from carbon-in-leach (CIL) and carbon-in-pulp (CIP) processes. The gold may be eluted from carbon fines with alkaline eluent having a low oxidation reduction potential (ORP). Value added products may be obtained from the extracted carbon fines.

Abstract: A computing device includes: a wireless communication interface; and a processor configured to: establish a connection with a wireless network; while a network-layer status of the connection is active, monitor attributes of the connection at the wireless communication interface, the attributes including (i) a number of uplink packets transmitted since a most recent downlink packet was received, and (ii) a time period elapsed since the most recent downlink packet was received; determine that the attributes meet recovery criteria indicative of a network-layer interruption in the wireless network; in response to the determination, control the wireless communication interface to initiate a recovery action to resolve the network-layer interruption.

Abstract: The present invention relates to a system, device, and method for the high throughput multiplexed detection of a wide number of compounds. The invention comprises of a microwell array coupled to a capture agent array to form a plurality of interfaces between a microwell and a set of immobilized capture agents. The set of capture agents comprises a plurality of distinguishable features, with each feature corresponding to the detection of a particular compound of interest. In certain embodiments, each microwell is configured to contain a single cell. The invention is therefore capable of performing a high throughput analysis of single cell profiles, including profiles of secreted compounds.

Abstract: The present invention relates to a system, device, and method for the high throughput multiplexed detection of a wide number of compounds. The invention comprises of a microwell array coupled to a capture agent array to form a plurality of interfaces between a microwell and a set of immobilized capture agents. The set of capture agents comprises a plurality of distinguishable features, with each feature corresponding to the detection of a particular compound of interest. In certain embodiments, each microwell is configured to contain a single cell. The invention is therefore capable of performing a high throughput analysis of single cell profiles, including profiles of secreted compounds.

Abstract: The present invention is generally directed to a colorectal (CRC) cell atlas that provides methods of predicting outcomes of cancer patients and therapeutic targets for treating patients in need thereof. The atlas may be used to predict a response to immunotherapy, in particular checkpoint blockade therapy and adoptive cell transfer. Disclosed herein are previously unidentified gene programs in tumors that can be used to predict response and provide for therapeutic targets that can be used to shift a tumor to a responsive phenotype.

Abstract: Example systems and methods improve a location detection process. A system accesses image data and image metadata, whereby the image data captures images of a plurality of objects from different views, each image having corresponding image metadata. The system then detects each object in the plurality of objects in the image data. A plurality of rays in three-dimensional space is generated, whereby each ray of the plurality of rays is generated based on the detected objects and the corresponding image metadata. The system predicts object locations using the generated rays based on a probabilistic triangulation of the rays. The networked system updates map data using the predicted object locations. The updating includes adding objects at their predicted object locations to the map data. The map data is used to generate a map.

Abstract: The present invention relates to a system, device, and method for the high throughput multiplexed detection of a wide number of compounds. The invention comprises of a microwell array coupled to a capture agent array to form a plurality of interfaces between a microwell and a set of immobilized capture agents. The set of capture agents comprises a plurality of distinguishable features, with each feature corresponding to the detection of a particular compound of interest. In certain embodiments, each microwell is configured to contain a single cell. The invention is therefore capable of performing a high throughput analysis of single cell profiles, including profiles of secreted compounds.

Abstract: The present invention relates to a system, device, and method for the high throughput multiplexed detection of a wide number of compounds. The invention comprises of a microwell array coupled to a capture agent array to form a plurality of interfaces between a microwell and a set of immobilized capture agents. The set of capture agents comprises a plurality of distinguishable features, with each feature corresponding to the detection of a particular compound of interest. In certain embodiments, each microwell is configured to contain a single cell. The invention is therefore capable of performing a high throughput analysis of single cell profiles, including profiles of secreted compounds.

Abstract: A programming system for device control is disclosed. The system includes a development board scanning module, a web server, and a working host. An application programming interface packaging module in the working host is a key part to translate high-level programming language codes into low-level programming language codes. Thus, using high-level programming language or interface to implement equipment control or development work becomes feasible.

Abstract: The invention provides a process for the leaching of a laterite ore or concentrate for the recovery of value metals, at least one value metal being nickel. The laterite ore or concentrate is subjected to a leaching step with a lixiviant comprising hydrochloric acid to leach nickel from the laterite ore. Nickel is extracted with an oxime at a lower pH than other processes for extraction of nickel from solution, especially after separation of iron and cobalt values.