Abstract: In some aspects, a non-transitory computer readable medium is disclosed that has an application stored thereon that when executed by a processor of an electronic device causes the processor to perform a process. The process can include receiving motion data from a motion sensor, the motion data being indicative of motion by a user while wearing the motion sensor. The process can also include transmitting the motion data to a server, receiving from the server a time that the motion data indicates a foot of the user experienced a loading force which risked adversely impacting an existing foot ulcer or causing a new foot ulcer, determining a geographic location of the motion sensor at the time that the foot experienced the loading force, displaying the time and the geographic location, and requesting that the user identify an activity engaged in by the user at the time and the geographic location.

Abstract: A latch assembly for mounting in an opening of a door and for releasably latching the door to a door frame. The latch assembly includes a housing that is mountable to the opening of the door. A lever is rotatably coupled to the housing between a deployed position and a retracted position. A lock plug is rotatably mounted within the housing, the lock plug having one end for receiving either a tool or key, and an opposite end having an engagement surface. A latching member is movably coupled to the housing, and is engaged with both the rotatable lock plug and the lever in the retracted position of the lever. A torsion spring biases the lock plug back to a starting position after the lock plug is rotated from the starting position using the tool or the key.

Abstract: There is provided a fan assembly comprising a motor-driven impeller arranged to generate an airflow, an air outlet arranged to emit the airflow, at least one filter assembly that is arranged to purify the airflow, a plurality of sensors arranged to measure a value for each of a plurality of air quality characteristic, and a processor. The processor is configured to receive measured values for each of the plurality of air quality characteristics, identify one of a corresponding set of intervals within which the measured value falls, select an air quality index value associated with the identified interval, and generate a corresponding speed value using the selected air quality index value. The processor is then configured to set a speed of the motor-driven impeller in dependence upon the highest of the speed values.

Abstract: A system and method to obtain activity data for an activity of a user, the activity data corresponding to multiple parameters. A set of threshold criteria that corresponds to a multi-parameter activity zone is retrieved, where the set of threshold criteria includes an effort threshold criteria related to a heart rate of the user. An effort of the user is determined based on the activity data. A resistance experienced by the user is determined, where the resistance includes a measure representing at least one of stride rate, step rate, steps, or cadence. A posture of the user is determined. Based on the set of threshold criteria corresponding to the multi-parameter activity zone, an instance of the activity is classified as an activity type based on the resistance experienced by the user, the effort of the user, and the posture of the user.

Abstract: A busway joint includes a first base portion, a second base portion, and at least one electrically conductive assembly. The at least one electrically conductive assembly includes: a first electrical conductor; and a second electrical conductor separated from the first electrical conductor by a space. The busway joint also includes a securing assembly. The securing assembly includes: a connection element that couples the first base portion and the second base portion; a cam assembly at a first end of the connection element, the cam assembly including a cam body configured for rotation between a released position and a closed position; a locking element; and a spring element between the locking element and the second exterior side. Rotating the cam body between the released position and the closed position changes an extent of the space.

Abstract: A method of producing a conductive nanoporous support, comprises: (i) producing an inorganic template by mixing and subjecting to high-energy ball milling an inorganic material and a powder selected from a carbonaceous material, a polymer, or a metal oxide; and (ii) coating the inorganic template with metal nanoparticles to obtain the nanoporous support. The invention further relates to a conductive nanoporous support, an electrolytic electrode, or gas diffusion electrode and an electrolytic cell or fuel cell.

Abstract: Methods and related systems for controlling an indoor air temperature for a heat pump system are disclosed. The method includes (a) determining an outdoor coil temperature of an outdoor heat exchanger and a speed of a compressor of a heat pump system, (b) determining a target indoor coil temperature of the indoor coil based on the outdoor coil temperature and the speed of the compressor, and (c) adjusting a speed of air flowing across the indoor coil based on a difference between a current indoor coil temperature and the target indoor coil temperature to reduce the difference between the current indoor coil temperature and the target indoor coil temperature.

Abstract: The invention relates to compounds which modulate the activity of ERK. The present invention also relates to processes for the preparation of said compounds, pharmaceutical compositions comprising said compounds, and use of said compounds in the treatment of conditions, diseases and disorders mediated by ERK.

Abstract: Probes and related systems and methods are provided for localizing markers implanted within a patient's body. The probe includes an antenna assembly adjacent a distal end thereof including a ceramic base including a planar distal surface and four proximal surfaces extending at an angle relative to a longitudinal axis of the probe to define a generally pyramidal shape. The base includes antenna elements on the proximal surfaces and radial slots between adjacent proximal surfaces to substantially isolate the antenna elements from one another. A controller is coupled to the antenna elements for transmitting signals into a patient's body and receiving reflected signals reflected from a marker implanted within the patient's body to identify and/or localize the marker.

Abstract: Methods and related systems for controlling indoor relative humidity include (a) determining a target dew point temperature based on desired indoor conditions for the indoor space, and (b) determining an initial dew point temperature based on an initial set of current indoor conditions of the indoor space. The method includes (c) determining a target coil temperature of a coil of an indoor heat exchanger of the climate control system based on the target dew point temperature and the initial dew point temperature, and (d) adjusting a speed of air flowing across the coil or a speed of a compressor of the climate control system after (c) based on the target coil temperature to reduce a difference between a coil temperature of the coil and the target coil temperature.

Abstract: The disclosure relates to double stranded ribonucleic acid (dsRNAi) agents and compositions targeting a heparan sulfate biosynthesis pathway enzyme gene (HSBPE) gene, e.g., Exostosin Glycosyltransferase 1 (EXT1), Exostosin Glycosyltransferase 2 (EXT2), and/or N-Deacetylase And N-Sulfotransferase 2, (NDST2 gene), as well as methods of inhibiting expression of an HSBPE gene and methods of treating subjects having Mucopolysaccaridosis type III (MPS III), e.g., MPS IIIA, MPS IIIB, MPS IIIC, or MPS IIID, using such dsRNAi agents and compositions.

Abstract: In various examples, multimodal image data may be used to generate a set of top-down tile images, which are applied to a deep neural network generator architecture model to produce lane marking-specific heatmap images corresponding to the set of top-down tile images. The multimodal sensor data may include LIDAR-captured intensity channel data, LIDAR-captured feature height channel data, and optical color image channel data. The set of top-down tile images may be processed by the generator model to automatically detect lane boundaries and navigation boundaries to generate pixel-level heatmap images that may classify lane markings by marking characteristics such as line type and/or color. The generator model may comprise an encoder-decoder architecture, with multiscale feature extraction and/or context extraction functional layers intervening between the encoder model and the decoder model.

Abstract: In some aspects, a non-transitory computer readable medium is disclosed that has an application stored thereon that when executed by a processor of an electronic device causes the processor to perform a process. The process can include receiving motion data from a motion sensor, the motion data being indicative of motion by a user while wearing the motion sensor. The process can also include transmitting the motion data to a server, receiving from the server a time that the motion data indicates a foot of the user experienced a loading force which risked adversely impacting an existing foot ulcer or causing a new foot ulcer, determining a geographic location of the motion sensor at the time that the foot experienced the loading force, displaying the time and the geographic location, and requesting that the user identify an activity engaged in by the user at the time and the geographic location.

Abstract: A roof protecting system for protecting the roof of a building from hail damage. The roof protecting system includes a roof covering structure adapted to cover a portion of the roof and capable of holding a non-Newtonian dilatant fluid; a deployment system to dispose the roof covering structure onto the roof; and a delivery system for delivering the non-Newtonian dilatant fluid to the roof covering structure.

Abstract: A dispenser head for in-line mixing and dispensing of beverages, which may be carbonated or nitrogenated. The dispenser head comprising a pump, a dilution mechanism, an additive mechanism, and outlet nozzle and optionally a regulation system. In use, the pump can pump concentrate liquid for the liquid product from a concentrate source to the dilution mechanism; the dilution mechanism can receive diluent liquid suitable for the liquid product from a diluent source, operable to mix the diluent liquid and the concentrate liquid and provide diluted concentrate liquid; and the additive mechanism can receive additive fluid for the liquid product from an additive source, to combine the diluted concentrate liquid and the additive fluid.

Abstract: The present application relates to pumps including: a first fluid port and a second fluid port, a housing having an interior surface defining a cavity, a rotor, being rotatably mounted within the housing, and comprising, a housing engaging surface area, and a surface recess that, a resiliently deformable diaphragm providing part of the interior surface of the housing, the rotor comprising an elongate body and a drive shaft, which body is substantially hollow and comprises separate first and second rotor cavities, the pump being arranged such that when the rotor body is located within the housing cavity, the first fluid port is in fluid flow communication with the first rotor cavity via the opening at the first end of the rotor, and the pump being arranged such that the resiliently deformable diaphragm always bisects the first opening and the second opening on the rotor surface recess as the rotor rotates.

Abstract: The need for a durable bottom dispensing package which is easy to dispense from, while having sufficient elasticity to return back to its original shape after dispensing, while also being easy to clean, and having reduced or no leakage during use, is met by making the container of the bottom dispensing package from an elastomer, and providing the interior surface of the container with at least one circumferentially oriented groove.

Abstract: A bottom dispensing package for a liquid composition includes a resiliently squeezable container for housing the liquid composition; and a base operably connected to the container, wherein the base comprises an orifice. The body of the base is at least partially made from an elastomer. The elastomer used in the base has a Shore A (Type A) hardness of from about 0 to about 80, and the shore A hardness is measured using the method described in ISO 868:2003.

Abstract: The need for a bottom dispensing packaging that can more easily reflate to its original shape, even when used with containers which are more flexible, is met when the container is provided with a one-way vent which allows the ingress of air into the container while preventing the egress of air from the container.

Abstract: The need for an improved durable bottom dispensing package that incorporates elastomer materials within the container, while enabling users to accurately dose both small and large quantities of the composition contained within, is met by forming the container of the bottom-dispensing package such that the container wall has a wider portion, such that at least part of the exterior surface of the container has a convex shape, and a narrow portion, such that at least part of the exterior surface of the container wall has a concave shape which is narrower than the adjacent parts of the container.