Abstract: Disclosed is a method and an oral composition for treating CNS disorders. An embodiment of the invention comprises orally administering an allopregnanolone containing composition to a subject having a CNS disorder. Exemplary CNS disorders include sleep disorders, mood disorders, dysthymic disorders, bipolar disorders, anxiety disorders, stress disorders, compulsive disorders, schizophrenia spectrum disorders, convulsive disorders, memory disorders, cognition disorders, movement disorders, personality disorders, autism spectrum disorders, substance abuse disorders, dementia, pain, traumatic brain injury (TBI), vascular disease, withdrawal syndrome, and tinnitus. The composition and methods disclosed herein exhibit effective oral absorption/bioavailability.

Abstract: A system and method for identifying abnormal medical images. The system can be configured to receive a medical image, segment an anatomical structure from the medical image to define a segmented dataset, register the segmented dataset to a baseline dataset defining a normal anatomical structure, classify, by an abnormality classifier, whether the anatomical structure within the medical image as either abnormal or normal, wherein the abnormality classifier comprises a machine learning algorithm trained to distinguish between normal and abnormal versions of the anatomical structure in medical images, and based on whether the anatomical structure can be segmented from the medical image, whether the segmented dataset can be registered to the baseline dataset, or a classification associated with the medical image output by the abnormality classifier, flagging the medical image as either normal or abnormal.

Abstract: When a client device loads a resource, a request for a first content item for a first content item slot is transmitted to a content item selection system. The content item selection system uses a predictive model to determine a predicted content item slot based on a document object model position of the first content item slot and a URL of the resource or a publisher identifier. Parameters for the predicted content item slot are used to select a subsequent content item for the predicted content item slot. The first content item and the subsequent content item are transmitted to the client device responsive to the request. The subsequent content item includes metadata indicative of the parameters of the predicted content item slot to be matched to a subsequent content item slot of the resource.

Abstract: There is provided breathable overpressure assemblies that are secured to a sealed container and configured to rupture in the event of a rapid pressure increase and to regulate pressure inside the container. A breathable overpressure assembly includes a rupture member having a central rupture portion and a peripheral flange extending about at least a portion of a periphery of the central rupture portion. The breathable overpressure assembly includes at least one vent opening in at least one of the central rupture portion and the peripheral flange, and a breathable membrane that covers the at least one vent opening.

Abstract: Within the field of advertising, multi-touch attribution (MTA) is the process of assigning credit at a unique identifier level to marketing activities for their contribution towards driving a desired marketing result. This invention discloses a data-driven attribution solution and optimization process for improving marketing return on investment by enabling greater speed and agility in responding to continually changing media performance. Specifically, this invention details a survival analysis based approach to attribution using parametric accelerated failure time (AFT) modeling which accommodates both the right-censored discrete time events and is well suited for media data.

Abstract: An optics arrangement for a solid immersion lens (SIL) is disclosed. The arrangement enables the SIL to freely tilt. The arrangement includes a SIL having an optical axis extending from an engaging surface and a rear surface of the SIL; a SIL housing having a cavity configured to accept the SIL therein while allowing the SIL to freely tilt within the cavity, wherein the cavity includes a hole positioned such that the optical axis passes there-through, to thereby allow light collected by the SIL to propagate to an objective lens; and, a SIL retainer attached to the SIL housing and configured to prevent the SIL from exiting the cavity.

Abstract: When a client device loads a resource, a request for a first content item for a first content item slot is transmitted to a content item selection system. The content item selection system uses a predictive model to determine a predicted content item slot based on a document object model position of the first content item slot and a URL of the resource or a publisher identifier. Parameters for the predicted content item slot are used to select a subsequent content item for the predicted content item slot. The first content item and the subsequent content item are transmitted to the client device responsive to the request. The subsequent content item includes metadata indicative of the parameters of the predicted content item slot to be matched to a subsequent content item slot of the resource.

Abstract: When a client device loads a resource, a request for a first content item for a first content item slot is transmitted to a content item selection system. The content item selection system uses a predictive model to determine a predicted content item slot based on a document object model position of the first content item slot and a URL of the resource or a publisher identifier. Parameters for the predicted content item slot are used to select a subsequent content item for the predicted content item slot. The first content item and the subsequent content item are transmitted to the client device responsive to the request. The subsequent content item includes metadata indicative of the parameters of the predicted content item slot to be matched to a subsequent content item slot of the resource.

Abstract: An optics arrangement for a solid immersion lens (SIL) is disclosed. The arrangement enables the SIL to freely tilt. The arrangement includes a SIL having an optical axis extending from an engaging surface and a rear surface of the SIL; a SIL housing having a cavity configured to accept the SIL therein while allowing the SIL to freely tilt within the cavity, wherein the cavity includes a hole positioned such that the optical axis passes there-through, to thereby allow light collected by the SIL to propagate to an objective lens; and, a SIL retainer attached to the SIL housing and configured to prevent the SIL from exiting the cavity.

Abstract: A combined video of a scene may be generated for applications such as virtual reality or augmented reality. In one method, a camera system may be oriented at a first orientation and used to capture first video of a first portion of the scene. The camera system may then be rotated to a second orientation and used to capture second video of a second portion of the scene that is offset from the first portion such that the first video and the second video each have an overlapping video portion depicting an overlapping portion of the scene in which the first portion and the second portion of the scene overlap with each other. The first and second portions may be combined together to generate the combined video, which may depict the first and second portions substantially without duplicative inclusion of the overlapping video portion.

Abstract: In one embodiment, a computing device determines a Completely Automated Public Turing Test to Tell Computers and Humans Apart (CAPTCHA). The CAPTCHA includes a first static image that has image sections that are arranged in a first order. Each of the image sections corresponds to a unique identifier. The CAPTCHA further includes a second static image that includes each of the image sections of the first static image that are arranged in a second order. The computing device generates web-browser-executable code for converting the second static image to the first static image based on the first static image, the first order, and the unique identifiers. The computing device sends the second static image and the web-browser-executable code to a client device.

Abstract: An optics arrangement for a solid immersion lens (SIL) is disclosed. The arrangement enables the SIL to freely tilt. The arrangement includes a SIL having an optical axis extending from an engaging surface and a rear surface of the SIL; a SIL housing having a cavity configured to accept the SIL therein while allowing the SIL to freely tilt within the cavity, wherein the cavity includes a hole positioned such that the optical axis passes there-through, to thereby allow light collected by the SIL to propagate to an objective lens; and, a SIL retainer attached to the SIL housing and configured to prevent the SIL from exiting the cavity.

Abstract: The invention relates to a method of identifying a fragrance sample using functional Magnetic Resonance Imaging to assess the ability of said fragrance sample to elicit a reward through the dopaminergic pathway; a fragrance sample identified by the method, and a method for preparing an accord or a fully formulated fragrance.

Abstract: In one embodiment, a computing device determines a Completely Automated Public Turing Test to Tell Computers and Humans Apart (CAPTCHA). The CAPTCHA includes a first static image that has image sections that are arranged in a first order. Each of the image sections corresponds to a unique identifier. The CAPTCHA further includes a second static image that includes each of the image sections of the first static image that are arranged in a second order. The computing device generates web-browser-executable code for converting the second static image to the first static image based on the first static image, the first order, and the unique identifiers. The computing device sends the second static image and the web-browser-executable code to a client device.

Abstract: In one embodiment, a client computing device receives information regarding a Completely Automated Public Turing Test to Tell Computers and Humans Apart (CAPTCHA). The CAPTCHA includes an image file, a challenge, and code that is executable by a web browser to unscramble the received image file. The code includes instructions to divide the received image file into image sections, each image section having a unique identifier and grouped into either a first set or a second set. The code further contains instructions to transpose each image section in the first set into a new position, creating a new image. A web browser of the client computing device executes the code to create a second image from the received image file. The second image and the challenge are presented to a user of the client computing device.

Abstract: Systems and methods for providing interstitial content are disclosed. A notification of an opportunity for presenting interstitial content on a client device is received at a content server. The content server generates an interstitial configuration object including computer-readable instructions for presenting the interstitial content on the client device and delivers the interstitial configuration object for execution by the client device. The interstitial configuration object causes the client device to render the interstitial content as a hidden element of a first resource while the first resource is presented on the client device and to reveal the rendered interstitial content in response to a user command to navigate away from the first resource.

Abstract: The present invention relates to core shell microcapsules for use in liquid consumer products, wherein: the microcapsule shell is made of starting materials such that 50%-100% by weight of said materials have a density equal to or less than 1.05 g/cm3; the microcapsule core contains a fragrance composition comprising 20-100% by weight of at least one cyclic fragrance material with a density greater than 0.950 g/cm3 and a ClogP in the range of from 1.00 to 6.00; the weight ratio of core materials to shell materials is in the range from about 50:1 to about 1:1.