Patents by Inventor Jonathan K. Stiles

Jonathan K. Stiles has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210275582
    Abstract: A nutritional supplement composition for treating nutritional deficiencies caused by a medical condition in subjects is disclosed. The present application further discloses a method of using a nutritional supplements composition for treating a subject with complications resulting from sickle cell anemia. The method comprises administering to a subject an effective amount of the nutritional supplement.
    Type: Application
    Filed: May 24, 2021
    Publication date: September 9, 2021
    Inventors: Jacqueline Hibbert, Jonathan K. Stiles, Kayellen Umeakunne, Hyacinth I. Hyacinth
  • Patent number: 11058719
    Abstract: A nutritional supplement composition for treating nutritional deficiencies caused by a medical condition in subjects is disclosed. The present application further discloses a method of using a nutritional supplements composition for treating a subject with complications resulting from sickle cell anemia. The method comprises administering to a subject an effective amount of the nutritional supplement.
    Type: Grant
    Filed: November 10, 2015
    Date of Patent: July 13, 2021
    Assignee: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: Jacqueline Hibbert, Jonathan K. Stiles, Kayellen Umeakunne, Hyacinth I. Hyacinth
  • Patent number: 9375451
    Abstract: A nutritional supplement composition for treating nutritional deficiencies caused by a medical condition in subjects is disclosed. The present application further discloses a method of using a nutritional supplements composition for treating a subject with complications resulting from sickle cell anemia. The method comprises administering to a subject an effective amount of the nutritional supplement.
    Type: Grant
    Filed: July 28, 2014
    Date of Patent: June 28, 2016
    Assignee: NUTRIGLOBAL, INC.
    Inventors: Jacqueline M. Hibbert, Jonathan K. Stiles, Kayellen Umeakunne, Hyacinth I. Hyacinth
  • Publication number: 20160058819
    Abstract: A nutritional supplement composition for treating nutritional deficiencies caused by a medical condition in subjects is disclosed. The present application further discloses a method of using a nutritional supplements composition for treating a subject with complications resulting from sickle cell anemia. The method comprises administering to a subject an effective amount of the nutritional supplement.
    Type: Application
    Filed: November 10, 2015
    Publication date: March 3, 2016
    Inventors: Jacqueline Hibbert, Jonathan K. Stiles, Kayellen Umeakunne, Hyacinth I. Hyacinth
  • Publication number: 20150017260
    Abstract: A nutritional supplement composition for treating nutritional deficiencies caused by a medical condition in subjects is disclosed. The present application further discloses a method of using a nutritional supplements composition for treating a subject with complications resulting from sickle cell anemia. The method comprises administering to a subject an effective amount of the nutritional supplement.
    Type: Application
    Filed: July 28, 2014
    Publication date: January 15, 2015
    Inventors: Jacqueline M. Hibbert, Jonathan K. Stiles, Kayellen Umeakunne, Hyacinth I. Hyacinth
  • Patent number: 8846048
    Abstract: Biomarkers for predicting the severity of malaria and methods for their detection are disclosed. In one aspect, the present application discloses CXCL4, CXCL10, VEGF, PGDF, IL-1Ra, IL-8, MIP-1?, sFas, Fas-L, sTNF-R2, and sTNF-R1 as biomarkers for the severity of malaria. In another aspect, the present application discloses a method for determining the severity of malaria and predicting mortality due to cerebral malaria. The method comprises the detection of the biomarkers CXCL4 and/or CXCL10 and at least one more biomarker and determining the severity of malaria and predicting mortality due to cerebral malaria based upon the ratio of expression of the biomarkers in the subject versus the expression of the biomarkers in a control.
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: September 30, 2014
    Assignee: Morehouse School of Medicine
    Inventors: Jonathan K. Stiles, James W. Lillard, Henry Benjamin Armatei Armah, Nana Otoo Wilson
  • Patent number: 8840950
    Abstract: A nutritional supplement composition for treating nutritional deficiencies caused by a medical condition in subjects is disclosed. The present application further discloses a method of using a nutritional supplements composition for treating a subject with complications resulting from sickle cell anemia. The method comprises administering to a subject an effective amount of the nutritional supplement.
    Type: Grant
    Filed: May 11, 2011
    Date of Patent: September 23, 2014
    Inventors: Jacqueline M. Hibbert, Jonathan K. Stiles, Kayellen Umeakunne, Hyacinth I. Hyacinth
  • Publication number: 20130243761
    Abstract: The present invention provides a means of inhibiting the growth and metastasis of cancer cells by administering anti-chemokine antibodies. It is possible to identify the particular chemokines which are over-expressed in the tumor using methods of the invention and administer antibodies against that over-expressed chemokine.
    Type: Application
    Filed: May 3, 2013
    Publication date: September 19, 2013
    Applicant: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: James W. Lillard, JR., Shailesh Singh, Jonathan K. Stiles
  • Patent number: 8367807
    Abstract: Biomarkers for predicting the severity of malaria and methods for their detection are disclosed. In one aspect, the present application discloses CXCL4, CXCL10, VEGF, PGDF, IL-1Ra, IL-8, MIP-1?, sFas, Fas-L, sTNF-R2, and sTNF-R1 as biomarkers for the severity of malaria. In another aspect, the present application discloses a method for determining the severity of malaria and predicting mortality due to cerebral malaria. The method comprises the detection of the biomarkers CXCL4 and/or CXCL10 and at least one more biomarker and determining the severity of malaria and predicting mortality due to cerebral malaria based upon the ratio of expression of the biomarkers in the subject versus the expression of the biomarkers in a control.
    Type: Grant
    Filed: May 2, 2012
    Date of Patent: February 5, 2013
    Assignee: Morehouse School of Medicine
    Inventors: Jonathan K. Stiles, James W. Lillard, Henry B. Armatei Armah, Nana Otoo Wilson
  • Patent number: 8367350
    Abstract: Biomarkers for predicting the severity of malaria and methods for their detection are disclosed. In one aspect, the present application discloses CXCL4, CXCL10, VEGF, PGDF, IL-1Ra, IL-8, MIP-1?, sFas, Fas-L, sTNF-R2, and sTNF-R1 as biomarkers for the severity of malaria. In another aspect, the present application discloses a method for determining the severity of malaria and predicting mortality due to cerebral malaria. The method comprises the detection of the biomarkers CXCL4 and/or CXCL10 and at least one more biomarker and determining the severity of malaria and predicting mortality due to cerebral malaria based upon the ratio of expression of the biomarkers in the subject versus the expression of the biomarkers in a control.
    Type: Grant
    Filed: December 2, 2010
    Date of Patent: February 5, 2013
    Assignee: Morehouse School of Medicine
    Inventors: Jonathan K. Stiles, James W. Lillard, Henry B. Armatei Armah, Nana Otoo Wilson, Venkatachalam Udhayakumar
  • Publication number: 20130012415
    Abstract: Biomarkers for predicting the severity of malaria and methods for their detection are disclosed. In one aspect, the present application discloses CXCL4, CXCL10, VEGF, PGDF, IL-1Ra, IL-8, MIP-1?, sFas, Fas-L, sTNF-R2, and sTNF-R1 as biomarkers for the severity of malaria. In another aspect, the present application discloses a method for determining the severity of malaria and predicting mortality due to cerebral malaria. The method comprises the detection of the biomarkers CXCL4 and/or CXCL10 and at least one more biomarker and determining the severity of malaria and predicting mortality due to cerebral malaria based upon the ratio of expression of the biomarkers in the subject versus the expression of the biomarkers in a control.
    Type: Application
    Filed: May 2, 2012
    Publication date: January 10, 2013
    Applicant: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: Jonathan K. STILES, James W. LILLARD, Henry B. Armatei ARMAH, Nana Otoo WILSON
  • Publication number: 20120315272
    Abstract: It is possible to inhibit inflammatory processes by administration of antibodies to chemokines. Identification of chemokines which are over-produced makes it possible to block specific chemokine activity using antibodies to the over-expressed chemokines.
    Type: Application
    Filed: June 29, 2012
    Publication date: December 13, 2012
    Applicant: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: James W. Lillard, JR., Udai P. Singh, Shailesh Singh, Jonathan K. Stiles
  • Patent number: 8318170
    Abstract: It is possible to inhibit inflammatory processes by administration of antibodies to chemokines. Identification of chemokines which are over-produced makes it possible to block specific chemokine activity using antibodies to the over-expressed chemokines.
    Type: Grant
    Filed: May 11, 2011
    Date of Patent: November 27, 2012
    Assignee: Morehouse School of Medicine
    Inventors: James W. Lillard, Udai P. Singh, Shailesh Singh, Jonathan K. Stiles
  • Patent number: 8097250
    Abstract: The present invention provides a means of inhibiting the growth and metastasis of cancer cells by administering anti-chemokine antibodies. It is possible to identify the particular chemokines which are over-expressed in the tumor using methods of the invention and administer antibodies against that over-expressed chemokine.
    Type: Grant
    Filed: December 14, 2010
    Date of Patent: January 17, 2012
    Assignee: Morehouse School of Medicine
    Inventors: James W. Lillard, Shailesh Singh, Jonathan K. Stiles
  • Publication number: 20110294727
    Abstract: A nutritional supplement composition for treating nutritional deficiencies caused by a medical condition in subjects is disclosed. The present application further discloses a method of using a nutritional supplements composition for treating a subject with complications resulting from sickle cell anemia. The method comprises administering to a subject an effective amount of the nutritional supplement.
    Type: Application
    Filed: May 11, 2011
    Publication date: December 1, 2011
    Applicant: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: Jacqueline M. Hibbert, Jonathan K. Stiles, Kayellen Umeakunne, Hyacinth I. Hyacinth
  • Publication number: 20110287063
    Abstract: It is possible to inhibit inflammatory processes by administration of antibodies to chemokines. Identification of chemokines which are over-produced makes it possible to block specific chemokine activity using antibodies to the over-expressed chemokines.
    Type: Application
    Filed: May 10, 2011
    Publication date: November 24, 2011
    Applicant: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: James W. Lillard, JR., Udai P. Singh, Shailesh Singh, Jonathan K. Stiles
  • Publication number: 20110280872
    Abstract: It is possible to inhibit inflammatory processes by administration of antibodies to chemokines. Identification of chemokines which are over-produced makes it possible to block specific chemokine activity using antibodies to the over-expressed chemokines.
    Type: Application
    Filed: May 11, 2011
    Publication date: November 17, 2011
    Applicant: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: James W. LILLARD, Udai P. Singh, Shailesh Singh, Jonathan K. Stiles
  • Publication number: 20110280871
    Abstract: It is possible to inhibit inflammatory processes by administration of antibodies to chemokines. Identification of chemokines which are over-produced makes it possible to block specific chemokine activity using antibodies to the over-expressed chemokines.
    Type: Application
    Filed: May 11, 2011
    Publication date: November 17, 2011
    Applicant: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: James W. LILLARD, Udai P. Singh, Shailesh Singh, Jonathan K. Stiles
  • Publication number: 20110150982
    Abstract: The present invention provides a means of inhibiting the growth and metastasis of cancer cells by administering anti-chemokine antibodies. It is possible to identify the particular chemokines which are over-expressed in the tumor using methods of the invention and administer antibodies against that over-expressed chemokine.
    Type: Application
    Filed: January 26, 2011
    Publication date: June 23, 2011
    Applicant: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: James W. Lillard, Shailesh Singh, Jonathan K. Stiles
  • Patent number: 7964194
    Abstract: It is possible to inhibit inflammatory processes by administration of antibodies to chemokines. Identification of chemokines which are over-produced makes it possible to block specific chemokine activity using antibodies to the over-expressed chemokines.
    Type: Grant
    Filed: November 14, 2003
    Date of Patent: June 21, 2011
    Assignee: Morehouse School of Medicine
    Inventors: James W. Lillard, Jr., Udai P. Singh, Shailesh Singh, Jonathan K. Stiles