Patents by Inventor Jonathan Kwok
Jonathan Kwok has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9216291Abstract: A neural stimulation system controls the delivery of neural stimulation using a respiratory signal as a therapy feedback input. The respiratory signal is used to increase the effectiveness of the neural stimulation, such as vagal nerve stimulation, while decreasing potentially adverse side effects in respiratory functions. In one embodiment, the neural stimulation system detects apnea and, in response, adjusts the delivery of the neural stimulation pulses and/or delivers a respiratory therapy treating the detected apnea.Type: GrantFiled: June 5, 2013Date of Patent: December 22, 2015Assignee: Cardiac Pacemakers, Inc.Inventors: Kent Lee, Imad Libbus, Anthony V. Caparso, Jonathan Kwok, Yachuan Pu, Paul A. Haefner, Kristofer J. James
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Patent number: 8923971Abstract: A neural stimulation system controls the delivery of neural stimulation using a respiratory signal as a therapy feedback input. The respiratory signal is used to increase the effectiveness of the neural stimulation, such as vagal nerve stimulation, while decreasing potentially adverse side effects in respiratory functions. In one embodiment, the neural stimulation system synchronizes the delivery of the neural stimulation pulses to the respiratory cycles using a respiratory fiducial point in the respiratory signal and a delay interval. In another embodiment, the neural stimulation system detects a respiratory disorder and, in response, adjusts the delivery of the neural stimulation pulses and/or delivers a respiratory therapy treating the detected respiratory disorder.Type: GrantFiled: September 30, 2013Date of Patent: December 30, 2014Assignee: Cardiac Pacemakers, Inc.Inventors: Paul A. Haefner, Kristofer J. James, Kent Lee, Imad Libbus, Anthony V. Caparso, Jonathan Kwok, Yachuan Pu
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Patent number: 8914113Abstract: An inspiratory muscle stimulation system uses an implantable medical device to deliver stimulation to control diaphragmatic contractions for slower and deeper breathing, thereby conditioning and strengthening inspiratory muscles. In various embodiments, respiratory and/or cardiac performance are monitored for controlling parameters of the stimulation.Type: GrantFiled: March 5, 2012Date of Patent: December 16, 2014Assignee: Cardiac Pacemakers, Inc.Inventors: Yi Zhang, Shantha Arcot-Krishnamurthy, Lili Liu, Kenneth C. Beck, Kent Lee, Jonathan Kwok, Zheng Lin
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Patent number: 8838245Abstract: A system and method for treating and/or preventing is described for treating periodic breathing characterized by cyclical hyperventilation and hypoventilation, examples of which include Cheyne-Stokes respiration and central sleep apnea. The system could also be used in the treatment of other conditions involving an impairment of respiratory drive.Type: GrantFiled: April 22, 2013Date of Patent: September 16, 2014Assignee: Cardiac Pacemakers, Inc.Inventors: Zheng Lin, Kenneth C. Beck, Jonathan Kwok, Kent Lee, Yachuan Pu, Jeffrey E. Stahmann
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Patent number: 8761876Abstract: Vector selection is automatically achieved via a thoracic or intracardiac impedance signal collected in a cardiac function management device or other implantable medical device that includes a test mode and a diagnostic mode. During a test mode, the device cycles through various electrode configurations for collecting thoracic impedance data. At least one figure of merit is calculated from the impedance data for each such electrode configuration. In one example, only non-arrhythmic beats are used for computing the figure of merit. A particular electrode configuration is automatically selected using the figure of merit. During a diagnostic mode, the device collects impedance data using the selected electrode configuration. In one example, the figure of merit includes a ratio of a cardiac stroke amplitude and a respiration amplitude. Other examples of the figure of merit are also described.Type: GrantFiled: June 24, 2013Date of Patent: June 24, 2014Assignee: Cardiac Pacemakers, Inc.Inventors: Jonathan Kwok, Kent Lee, Jesse W. Hartley, Jeffrey E. Stahmann, Yinghong Yu, Jiang Ding
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Publication number: 20140025141Abstract: A neural stimulation system controls the delivery of neural stimulation using a respiratory signal as a therapy feedback input. The respiratory signal is used to increase the effectiveness of the neural stimulation, such as vagal nerve stimulation, while decreasing potentially adverse side effects in respiratory functions. In one embodiment, the neural stimulation system synchronizes the delivery of the neural stimulation pulses to the respiratory cycles using a respiratory fiducial point in the respiratory signal and a delay interval. In another embodiment, the neural stimulation system detects a respiratory disorder and, in response, adjusts the delivery of the neural stimulation pulses and/or delivers a respiratory therapy treating the detected respiratory disorder.Type: ApplicationFiled: September 30, 2013Publication date: January 23, 2014Applicant: Cardiac Pacemakers, Inc.Inventors: Paul A. Haefner, Kristofer J. James, Kent Lee, Imad Libbus, Anthony V. Caparso, Jonathan Kwok, Yachuan Pu
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Publication number: 20130281867Abstract: Vector selection is automatically achieved via a thoracic or intracardiac impedance signal collected in a cardiac function management device or other implantable medical device that includes a test mode and a diagnostic mode. During a test mode, the device cycles through various electrode configurations for collecting thoracic impedance data. At least one figure of merit is calculated from the impedance data for each such electrode configuration. In one example, only non-arrhythmic beats are used for computing the figure of merit. A particular electrode configuration is automatically selected using the figure of merit. During a diagnostic mode, the device collects impedance data using the selected electrode configuration. In one example, the figure of merit includes a ratio of a cardiac stroke amplitude and a respiration amplitude. Other examples of the figure of merit are also described.Type: ApplicationFiled: June 24, 2013Publication date: October 24, 2013Inventors: Jonathan Kwok, Kent Lee, Jesse W. Hartley, Jeffrey E. Stahmann, Yinghong Yu, Jiang Ding
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Patent number: 8560072Abstract: A system, device and method for neural control of respiration are provided. One aspect of this disclosure relates to an implantable medical device for sensing and controlling respiration during incidence of central respiratory diseases. According to various embodiments, the device includes a sensing circuit to receive sensed signals representative of an incidence of a central respiratory disease. The device also includes a neural stimulator adapted to generate neural stimulation signals, and a controller to communicate with the sensing circuit and to control the neural stimulator to stimulate a desired neural target in response to the detection of the incidence of a central respiratory disease. In an embodiment, the device includes a plurality of sensors which are adapted to monitor physiological parameters to detect the incidence of a central respiratory disease and to send signals to the sensing circuit. Other aspects and embodiments are provided herein.Type: GrantFiled: August 28, 2012Date of Patent: October 15, 2013Assignee: Cardiac Pacemakers, Inc.Inventors: Anthony V. Caparso, Imad Libbus, M. Jason Brooke, Kent Lee, Jonathan Kwok, Yachuan Pu
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Publication number: 20130268030Abstract: A neural stimulation system controls the delivery of neural stimulation using a respiratory signal as a therapy feedback input. The respiratory signal is used to increase the effectiveness of the neural stimulation, such as vagal nerve stimulation, while decreasing potentially adverse side effects in respiratory functions. In one embodiment, the neural stimulation system detects apnea and, in response, adjusts the delivery of the neural stimulation pulses and/or delivers a respiratory therapy treating the detected apnea.Type: ApplicationFiled: June 5, 2013Publication date: October 10, 2013Inventors: Kent Lee, Imad Libbus, Anthony V. Caparso, Jonathan Kwok, Yachuan Pu, Paul A. Haefner, Kristofer J. James
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Patent number: 8551010Abstract: An implantable respiration monitor can be used to detect disordered breathing or periodic breathing events that can be categorized, such as according to one or more of sleep, exercise, and resting awake states. The categorized frequency of such events can be compared to independently specifiable thresholds, such as to trigger an alert or responsive therapy, or to display one or more trends. The information can also be combined with detection of one or more other congestive heart failure (CHF) symptoms to generate a CHF status indicator or to trigger an alarm or responsive therapy or to display one or more trends. The alert can notify the patient or a caregiver, such as via remote monitoring. The sleep state information can be further categorized according to central sleep apnea (CSA) or obstructive sleep apnea (OSA) events.Type: GrantFiled: July 19, 2012Date of Patent: October 8, 2013Assignee: Cardiac Pacemakers, Inc.Inventors: Yachuan Pu, Kent Lee, Jonathan Kwok, Quan Ni
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Patent number: 8554323Abstract: A neural stimulation system controls the delivery of neural stimulation using a respiratory signal as a therapy feedback input. The respiratory signal is used to increase the effectiveness of the neural stimulation, such as vagal nerve stimulation, while decreasing potentially adverse side effects in respiratory functions. In one embodiment, the neural stimulation system synchronizes the delivery of the neural stimulation pulses to the respiratory cycles using a respiratory fiducial point in the respiratory signal and a delay interval. In another embodiment, the neural stimulation system detects a respiratory disorder and, in response, adjusts the delivery of the neural stimulation pulses and/or delivers a respiratory therapy treating the detected respiratory disorder.Type: GrantFiled: January 31, 2012Date of Patent: October 8, 2013Assignee: Cardiac Pacemakers, Inc.Inventors: Paul A. Haefner, Kristofer J. James, Kent Lee, Imad Libbus, Anthony V. Caparso, Jonathan Kwok, Yachuan Pu
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Publication number: 20130238051Abstract: A system and method for treating and/or preventing is described for treating periodic breathing characterized by cyclical hyperventilation and hypoventilation, examples of which include Cheyne-Stokes respiration and central sleep apnea. The system could also be used in the treatment of other conditions involving an impairment of respiratory drive.Type: ApplicationFiled: April 22, 2013Publication date: September 12, 2013Applicant: Cardiac Pacemakers, Inc.Inventors: Zheng Lin, Kenneth C. Beck, Jonathan Kwok, Kent Lee, Yachuan Pu, Jeffrey E. Stahmann
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Patent number: 8521289Abstract: This document discusses, among other things, methods and systems for facilitating automated device programming at changeout. A method comprises receiving, from a first device, physiological data at a temporary storage device; and processing the received physiological data, wherein the processing includes determining if a first signal processing function was used by the first device and substantially offsetting the first signal processing function if the first signal processing function was used by the first device; and processing the resultant physiological data to be compatible with a second device. The method further comprising providing the processed resultant physiological data to the second device.Type: GrantFiled: September 5, 2012Date of Patent: August 27, 2013Assignee: Cardiac Pacemakers, Inc.Inventors: Shelley M. Cazares, Dan Li, Jonathan Kwok
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Patent number: 8483834Abstract: A neural stimulation system controls the delivery of neural stimulation using a respiratory signal as a therapy feedback input. The respiratory signal is used to increase the effectiveness of the neural stimulation, such as vagal nerve stimulation, while decreasing potentially adverse side effects in respiratory functions. In one embodiment, the neural stimulation system detects apnea and, in response, adjusts the delivery of the neural stimulation pulses and/or delivers a respiratory therapy treating the detected apnea.Type: GrantFiled: October 31, 2011Date of Patent: July 9, 2013Assignee: Cardiac Pacemakers, Inc.Inventors: Kent Lee, Imad Libbus, Anthony V. Caparso, Jonathan Kwok, Yachuan Pu, Paul A. Haefner, Kristofer J. James
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Patent number: 8473050Abstract: Vector selection is automatically achieved via a thoracic or intracardiac impedance signal collected in a cardiac function management device or other implantable medical device that includes a test mode and a diagnostic mode. During a test mode, the device cycles through various electrode configurations for collecting thoracic impedance data. At least one figure of merit is calculated from the impedance data for each such electrode configuration. In one example, only non-arrhythmic beats are used for computing the figure of merit. A particular electrode configuration is automatically selected using the figure of merit. During a diagnostic mode, the device collects impedance data using the selected electrode configuration. In one example, the figure of merit includes a ratio of a cardiac stroke amplitude and a respiration amplitude. Other examples of the figure of merit are also described.Type: GrantFiled: July 19, 2011Date of Patent: June 25, 2013Assignee: Cardiac Pacemakers, Inc.Inventors: Jonathan Kwok, Kent Lee, Jesse W. Hartley, Jeffrey E. Stahmann, Yinghong Yu, Jiang Ding
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Patent number: 8428711Abstract: A system and method for treating and/or preventing is described for treating periodic breathing characterized by cyclical hyperventilation and hypoventilation, examples of which include Cheyne-Stokes respiration and central sleep apnea. The system could also be used in the treatment of other conditions involving an impairment of respiratory drive.Type: GrantFiled: October 10, 2008Date of Patent: April 23, 2013Assignee: Cardiac Pacemakers, Inc.Inventors: Zheng Lin, Kenneth C. Beck, Jonathan Kwok, Kent Lee, Yachuan Pu, Jeffrey E. Stahmann
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Patent number: 8401651Abstract: A system, device and method for neural control of respiration are provided. One aspect of this disclosure relates to an implantable medical device for sensing and controlling respiration during incidence of central respiratory diseases. According to various embodiments, the device includes a sensing circuit to receive sensed signals representative of an incidence of a central respiratory disease. The device also includes a neural stimulator adapted to generate neural stimulation signals, and a controller to communicate with the sensing circuit and to control the neural stimulator to stimulate a desired neural target in response to the detection of the incidence of a central respiratory disease. In an embodiment, the device includes a plurality of sensors which are adapted to monitor physiological parameters to detect the incidence of a central respiratory disease and to send signals to the sensing circuit. Other aspects and embodiments are provided herein.Type: GrantFiled: September 9, 2011Date of Patent: March 19, 2013Assignee: Cardiac Pacemakers, Inc.Inventors: Anthony V. Caparso, Imad Libbus, M. Jason Brooke, Kent Lee, Jonathan Kwok, Yachuan Pu
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Patent number: 8352032Abstract: Method and systems related to monitoring right ventricular function during pacing by a cardiac rhythm management device are described. One or more pacing parameters are selected to provide cardiac resynchronization therapy. For example, the one or more pacing parameters may be selected to provide an optimal or improved therapy. The heart is paced using the selected pacing parameters. While pacing with the selected parameters, pressure is sensed via a pressure sensor disposed the pulmonary artery. The sensed pressure is analyzed to determine right ventricular function achieved during the pacing using the selected pacing parameters. A signal, such as an alert signal or control signal, is generated based on the right ventricular function achieved during the pacing.Type: GrantFiled: September 22, 2008Date of Patent: January 8, 2013Assignee: Cardiac Pacemakers, Inc.Inventors: Abhilash Patangay, Barun Maskara, Jonathan Kwok, Jiang Ding, Yinghong Yu
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Publication number: 20120330381Abstract: This document discusses, among other things, methods and systems for facilitating automated device programming at changeout. A method comprises receiving, from a first device, physiological data at a temporary storage device; and processing the received physiological data, wherein the processing includes determining if a first signal processing function was used by the first device and substantially offsetting the first signal processing function if the first signal processing function was used by the first device; and processing the resultant physiological data to be compatible with a second device. The method further comprising providing the processed resultant physiological data to the second device.Type: ApplicationFiled: September 5, 2012Publication date: December 27, 2012Inventors: Shelley Cazares, Dan Li, Jonathan Kwok
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Publication number: 20120323292Abstract: A system, device and method for neural control of respiration are provided. One aspect of this disclosure relates to an implantable medical device for sensing and controlling respiration during incidence of central respiratory diseases. According to various embodiments, the device includes a sensing circuit to receive sensed signals representative of an incidence of a central respiratory disease. The device also includes a neural stimulator adapted to generate neural stimulation signals, and a controller to communicate with the sensing circuit and to control the neural stimulator to stimulate a desired neural target in response to the detection of the incidence of a central respiratory disease. In an embodiment, the device includes a plurality of sensors which are adapted to monitor physiological parameters to detect the incidence of a central respiratory disease and to send signals to the sensing circuit. Other aspects and embodiments are provided herein.Type: ApplicationFiled: August 28, 2012Publication date: December 20, 2012Inventors: Anthony Caparso, Imad Libbus, M. Jason Brooke, Kent Lee, Jonathan Kwok, Yachuan Pu