Patents by Inventor Jonathan Kwok
Jonathan Kwok has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20120283527Abstract: An implantable respiration monitor can be used to detect disordered breathing or periodic breathing events that can be categorized, such as according to one or more of sleep, exercise, and resting awake states. The categorized frequency of such events can be compared to independently specifiable thresholds, such as to trigger an alert or responsive therapy, or to display one or more trends. The information can also be combined with detection of one or more other congestive heart failure (CHF) symptoms to generate a CHF status indicator or to trigger an alarm or responsive therapy or to display one or more trends. The alert can notify the patient or a caregiver, such as via remote monitoring. The sleep state information can be further categorized according to central sleep apnea (CSA) or obstructive sleep apnea (OSA) events.Type: ApplicationFiled: July 19, 2012Publication date: November 8, 2012Inventors: Yachuan Pu, Kent Lee, Jonathan Kwok, Quan Ni
-
Patent number: 8271088Abstract: This document discusses, among other things, methods and systems for facilitating automated device programming at changeout. A method comprises receiving, from a first device, physiological data at a temporary storage device; and processing the received physiological data, wherein the processing includes determining if a first signal processing function was used by the first device and substantially offsetting the first signal processing function if the first signal processing function was used by the first device; and processing the resultant physiological data to be compatible with a second device. The method further comprising providing the processed resultant physiological data to the second device.Type: GrantFiled: July 20, 2010Date of Patent: September 18, 2012Assignee: Cardiac Pacemakers, Inc.Inventors: Shelley M. Cazares, Dan Li, Jonathan Kwok
-
Patent number: 8226570Abstract: An implantable respiration monitor can be used to detect disordered breathing or periodic breathing events that can be categorized, such as according to one or more of sleep, exercise, and resting awake states. The categorized frequency of such events can be compared to independently specifiable thresholds, such as to trigger an alert or responsive therapy, or to display one or more trends. The information can also be combined with detection of one or more other congestive heart failure (CHF) symptoms to generate a CHF status indicator or to trigger an alarm or responsive therapy or to display one or more trends. The alert can notify the patient or a caregiver, such as via remote monitoring. The sleep state information can be further categorized according to central sleep apnea (CSA) or obstructive sleep apnea (OSA) events.Type: GrantFiled: August 8, 2006Date of Patent: July 24, 2012Assignee: Cardiac Pacemakers, Inc.Inventors: Yachuan Pu, Kent Lee, Jonathan Kwok, Quan Ni
-
Publication number: 20120165889Abstract: An inspiratory muscle stimulation system uses an implantable medical device to deliver stimulation to control diaphragmatic contractions for slower and deeper breathing, thereby conditioning and strengthening inspiratory muscles. In various embodiments, respiratory and/or cardiac performance are monitored for controlling parameters of the stimulation.Type: ApplicationFiled: March 5, 2012Publication date: June 28, 2012Inventors: YI ZHANG, SHANTHA ARCOT-KRISHNAMUTHY, LILI LIU, KENNETH C. BECK, KENT LEE, JONATHAN KWOK, ZHENG LIN
-
Publication number: 20120130446Abstract: A neural stimulation system controls the delivery of neural stimulation using a respiratory signal as a therapy feedback input. The respiratory signal is used to increase the effectiveness of the neural stimulation, such as vagal nerve stimulation, while decreasing potentially adverse side effects in respiratory functions. In one embodiment, the neural stimulation system synchronizes the delivery of the neural stimulation pulses to the respiratory cycles using a respiratory fiducial point in the respiratory signal and a delay interval. In another embodiment, the neural stimulation system detects a respiratory disorder and, in response, adjusts the delivery of the neural stimulation pulses and/or delivers a respiratory therapy treating the detected respiratory disorder.Type: ApplicationFiled: January 31, 2012Publication date: May 24, 2012Inventors: Paul A. Haefner, Kristofer J. James, Kent Lee, Imad Libbus, Anthony V. Caparso, Jonathan Kwok, Yachuan Pu
-
Patent number: 8135471Abstract: An inspiratory muscle stimulation system uses an implantable medical device to deliver stimulation to control diaphragmatic contractions for slower and deeper breathing, thereby conditioning and strengthening inspiratory muscles. In various embodiments, respiratory and/or cardiac performance are monitored for controlling parameters of the stimulation.Type: GrantFiled: August 28, 2007Date of Patent: March 13, 2012Assignee: Cardiac Pacemakers, Inc.Inventors: Yi Zhang, Shantha Arcot-Krishnamurthy, Lili Liu, Kenneth C. Beck, Kent Lee, Jonathan Kwok, Zheng Lin
-
Publication number: 20120046709Abstract: A neural stimulation system controls the delivery of neural stimulation using a respiratory signal as a therapy feedback input. The respiratory signal is used to increase the effectiveness of the neural stimulation, such as vagal nerve stimulation, while decreasing potentially adverse side effects in respiratory functions. In one embodiment, the neural stimulation system detects apnea and, in response, adjusts the delivery of the neural stimulation pulses and/or delivers a respiratory therapy treating the detected apnea.Type: ApplicationFiled: October 31, 2011Publication date: February 23, 2012Inventors: Kent Lee, Imad Libbus, Anthony V. Caparso, Jonathan Kwok, Yachuan Pu, Paul A. Haefner, Kristofer J. James
-
Patent number: 8121692Abstract: A neural stimulation system controls the delivery of neural stimulation using a respiratory signal as a therapy feedback input. The respiratory signal is used to increase the effectiveness of the neural stimulation, such as vagal nerve stimulation, while decreasing potentially adverse side effects in respiratory functions. In one embodiment, the neural stimulation system synchronizes the delivery of the neural stimulation pulses to the respiratory cycles using a respiratory fiducial point in the respiratory signal and a delay interval. In another embodiment, the neural stimulation system detects a respiratory disorder and, in response, adjusts the delivery of the neural stimulation pulses and/or delivers a respiratory therapy treating the detected respiratory disorder.Type: GrantFiled: August 30, 2006Date of Patent: February 21, 2012Assignee: Cardiac Pacemakers, Inc.Inventors: Paul A. Haefner, Kristofer J. James, Kent Lee, Imad Libbus, Anthony V. Caparso, Jonathan Kwok, Yachuan Pu
-
Publication number: 20110319959Abstract: A system, device and method for neural control of respiration are provided. One aspect of this disclosure relates to an implantable medical device for sensing and controlling respiration during incidence of central respiratory diseases. According to various embodiments, the device includes a sensing circuit to receive sensed signals representative of an incidence of a central respiratory disease. The device also includes a neural stimulator adapted to generate neural stimulation signals, and a controller to communicate with the sensing circuit and to control the neural stimulator to stimulate a desired neural target in response to the detection of the incidence of a central respiratory disease. In an embodiment, the device includes a plurality of sensors which are adapted to monitor physiological parameters to detect the incidence of a central respiratory disease and to send signals to the sensing circuit. Other aspects and embodiments are provided herein.Type: ApplicationFiled: September 9, 2011Publication date: December 29, 2011Inventors: Anthony Caparso, Imad Libbus, M. Jason Brooke, Kent Lee, Jonathan Kwok, Yachuan Pu
-
Publication number: 20110301471Abstract: Vector selection is automatically achieved via a thoracic or intracardiac impedance signal collected in a cardiac function management device or other implantable medical device that includes a test mode and a diagnostic mode. During a test mode, the device cycles through various electrode configurations for collecting thoracic impedance data. At least one figure of merit is calculated from the impedance data for each such electrode configuration. In one example, only non-arrhythmic beats are used for computing the figure of merit. A particular electrode configuration is automatically selected using the figure of merit. During a diagnostic mode, the device collects impedance data using the selected electrode configuration. In one example, the figure of merit includes a ratio of a cardiac stroke amplitude and a respiration amplitude. Other examples of the figure of merit are also described.Type: ApplicationFiled: July 19, 2011Publication date: December 8, 2011Inventors: Jonathan Kwok, Kent Lee, Jesse W. Hartley, Jeffrey E. Stahmann, Yinghong Yu, Jiang Ding
-
Patent number: 8050765Abstract: A neural stimulation system controls the delivery of neural stimulation using a respiratory signal as a therapy feedback input. The respiratory signal is used to increase the effectiveness of the neural stimulation, such as vagal nerve stimulation, while decreasing potentially adverse side effects in respiratory functions. In one embodiment, the neural stimulation system detects apnea and, in response, adjusts the delivery of the neural stimulation pulses and/or delivers a respiratory therapy treating the detected apnea.Type: GrantFiled: August 30, 2006Date of Patent: November 1, 2011Assignee: Cardiac Pacemakers, Inc.Inventors: Kent Lee, Imad Libbus, Anthony V. Caparso, Jonathan Kwok, Yachuan Pu, Paul A. Haefner, Kristofer J. James
-
Patent number: 8036750Abstract: A system, device and method for neural control of respiration are provided. One aspect of this disclosure relates to an implantable medical device for sensing and controlling respiration during incidence of central respiratory diseases. According to various embodiments, the device includes a sensing circuit to receive sensed signals representative of an incidence of a central respiratory disease. The device also includes a neural stimulator adapted to generate neural stimulation signals, and a controller to communicate with the sensing circuit and to control the neural stimulator to stimulate a desired neural target in response to the detection of the incidence of a central respiratory disease. In an embodiment, the device includes a plurality of sensors which are adapted to monitor physiological parameters to detect the incidence of a central respiratory disease and to send signals to the sensing circuit. Other aspects and embodiments are provided herein.Type: GrantFiled: June 13, 2005Date of Patent: October 11, 2011Assignee: Cardiac Pacemakers, Inc.Inventors: Anthony Caparso, Imad Libbus, M. Jason Brooke, Kent Lee, Jonathan Kwok, Yachuan Pu
-
Patent number: 8014860Abstract: Vector selection is automatically achieved via a thoracic or intracardiac impedance signal collected in a cardiac function management device or other implantable medical device that includes a test mode and a diagnostic mode. During a test mode, the device cycles through various electrode configurations for collecting thoracic impedance data. At least one figure of merit is calculated from the impedance data for each such electrode configuration. In one example, only non-arrhythmic beats are used for computing the figure of merit. A particular electrode configuration is automatically selected using the figure of merit. During a diagnostic mode, the device collects impedance data using the selected electrode configuration. In one example, the figure of merit includes a ratio of a cardiac stroke amplitude and a respiration amplitude. Other examples of the figure of merit are also described.Type: GrantFiled: November 4, 2009Date of Patent: September 6, 2011Assignee: Cardiac Pacemakers, Inc.Inventors: Jonathan Kwok, Kent Lee, Jesse W. Hartley, Jeffrey E. Stahmann, Yinghong Yu, Jiang Ding
-
Patent number: 7922663Abstract: An apparatus comprising an implantable acoustic transducer, an acoustic transducer interface circuit communicatively coupled to the acoustic transducer, and a controller circuit communicatively coupled to the acoustic transducer interface circuit. The controller is configured to, in response to receiving an indication of a patient condition associated with a development of a blood vessel obstruction, initiate delivery of acoustic energy that mitigates the blood vessel obstruction. Other systems and methods are described.Type: GrantFiled: September 24, 2007Date of Patent: April 12, 2011Assignee: Cardiac Pacemakers, Inc.Inventors: Binh C. Tran, Abhi Chavan, Rodney W. Salo, Jonathan Kwok
-
Publication number: 20110040201Abstract: Systems and methods are directed to evaluating breathing disorders, such as periodic disordered breathing. A signal representative of patient respiration is developed, typically patient-internally. An envelope of the signal is provided. Periodicity of the envelope is detected, and presence and severity of periodic disordered breathing is determined based on the periodicity of the envelope.Type: ApplicationFiled: October 25, 2010Publication date: February 17, 2011Inventors: Yanchuan Pu, Kent Lee, Jonathan Kwok, Zheng Lin
-
Publication number: 20100298733Abstract: An evaluation of heart failure status is provided based on a disordered breathing index. Patient respiration is sensed and a respiration signal is generated. Disordered breathing episodes are detected based on the respiration signal. A disordered breathing index is determined based on the disordered breathing episodes. The disordered breathing index is trended and used to evaluate heart failure status. The disordered breathing index may be combined with additional information and/or may take into account patient activity, posture, sleep stage, or other patient information.Type: ApplicationFiled: July 30, 2010Publication date: November 25, 2010Inventors: Jonathan Kwok, Marina Brockway, Kent Lee, Quan Ni, Yachuan Pu, Jeffrey Stahmann, Yi Zhang, Jesse Hartley
-
Publication number: 20100292761Abstract: This document discusses, among other things, methods and systems for facilitating automated device programming at changeout. A method comprises receiving, from a first device, physiological data at a temporary storage device; and processing the received physiological data, wherein the processing includes determining if a first signal processing function was used by the first device and substantially offsetting the first signal processing function if the first signal processing function was used by the first device; and processing the resultant physiological data to be compatible with a second device. The method further comprising providing the processed resultant physiological data to the second device.Type: ApplicationFiled: July 20, 2010Publication date: November 18, 2010Inventors: Shelley Cazares, Dan Li, Jonathan Kwok
-
Patent number: 7819816Abstract: Systems and methods are directed to evaluating breathing disorders, such as periodic disordered breathing. A signal representative of patient respiration is developed, typically patient-internally. An envelope of the signal is provided. Periodicity of the envelope is detected, and presence and severity of periodic disordered breathing is determined based on the periodicity of the envelope.Type: GrantFiled: March 29, 2006Date of Patent: October 26, 2010Assignee: Cardiac Pacemakers, Inc.Inventors: Yanchuan Pu, Kent Lee, Jonathan Kwok, Zheng Lin
-
Patent number: 7809441Abstract: In an embodiment, the invention includes an implantable medical device with a pulse generator and a chemical sensor in communication with the pulse generator, the chemical sensor configured to detect an ion concentration in a bodily fluid. In an embodiment, the invention includes a method for providing cardiac arrhythmia therapy to a patient including sensing a physiological concentration of an analyte, communicating data regarding the physiological concentration of the analyte to an implanted pulse generator, and delivering therapy to the patient based in part on the physiological concentration of the ion. In an embodiment, the invention includes a method for monitoring diuretic therapy. In an embodiment, the invention includes a method for controlling delivery of an active agent into a human body. Other aspects and embodiments are provided herein.Type: GrantFiled: May 17, 2006Date of Patent: October 5, 2010Assignee: Cardiac Pacemakers, Inc.Inventors: Michael John Kane, Jeffrey Allen Von Arx, James Gregory Bentsen, Jonathan Kwok
-
Patent number: 7797050Abstract: Various aspects relate to an implantable device. Various device embodiments include at least one sensor for use in detecting sleep disordered breathing, a pulse generator adapted to deliver a first electrical signal through at least one electrode to stimulate a neural target, and a controller adapted to communicate with the at least one sensor and with the pulse generator. The controller is adapted to detect sleep disordered breathing using the at least one sensor and provide a therapy for sleep disordered breathing in response to a detected apneic event. The therapy for sleep disordered breathing is adapted to deliver the first electrical signal through the at least one electrode to induce a cough reflex to terminate the apneic event. Various embodiments stimulate a superior laryngeal nerve, various embodiments stimulate a recurrent laryngeal nerve, and various embodiments stimulate a vagus nerve. Other aspects and embodiments are provided herein.Type: GrantFiled: January 21, 2010Date of Patent: September 14, 2010Assignee: Cardiac Pacemakers, Inc.Inventors: Imad Libbus, Anthony V. Caparso, M. Jason Brooke, Jonathan Kwok, Kent Lee, Yachuan Pu