Abstract: An airline operations system, controller and method reschedules flights affected by a disruption that precludes a planned schedule for the flights. The method includes obtaining data related to a scheduled origination and a scheduled destination for each of a set of passengers scheduled on the flights, generating a passenger connection network of connections between the scheduled origination and the scheduled destination for a subset of the set of passengers, applying at least one criterion to the passenger connection network and rescheduling at least one connecting flight based on the criteria. The system and controller solves a network flow problem to reschedule a subset of connecting flights to have a delayed projected departure time. Resulting output can include the set of delayed flights along with modified projected departure times, a set of flight cancellations and a set of passengers with missed connections.

Abstract: Systems, apparatus, and methods for continuously authenticating individuals are provided. A continuous authentication system receives first biometric authentication information from an individual. The system compares the first biometric authentication information to stored first biometric information to identify the individual and links the identified individual to a device for obtaining second biometric authentication information. The device for obtaining second biometric authentication information continuously receives second biometric authentication information. The continuous authentication system compares the received second biometric authentication information to stored second biometric information that corresponds to the individual to determine if the received second biometric authentication information corresponds to the individual.

Abstract: A respiratory mask system comprising a mask interface comprising a frame for a headgear assembly. The frame comprises a body comprising a first surface and a substantially opposing second surface. The body further comprises a gas inlet and optionally an outlet vent. The gas inlet may be substantially elliptical in shape. The frame may comprise a recessed region for receiving yoke of a headgear assembly to attach the headgear to the mask interface. The respiratory mask system may also comprise a yoke for attaching to the frame.

Abstract: The present invention provides methods for creating an array of features on a surface based on content transferred from a plurality of beads to the surface. Nucleic acid content can be transferred using a method including the steps of (a) providing a surface having one or more primer oligonucleotides attached to the surface; (b) providing a pool of beads, wherein beads in the pool have a plurality of templates attached thereto, the plurality comprising multiple copies of a single nucleic acid template sequence; (c) arraying the beads onto the surface by hybridizing the templates to the primer oligonucleotides; and (d) extending the primers to produce copies of the templates attached to the surface.

Abstract: The present disclosure provides methods and systems for detecting multiple different nucleotides in a sample. In particular, the disclosure provides for detection of multiple different nucleotides in a sample utilizing fewer detection moieties than the number of nucleotides being detected and/or fewer imaging events than the number of nucleotides being detected.

Abstract: An electrical connector for a glazing comprising a connector portion for connection to an electrical supply, and a button for soldering to a surface of the glazing, the button comprising a base portion adjacent, in use, to the surface of the glazing and an upper portion remote, in use, from the surface of the glazing, wherein the button comprises at least one solder-contacting surface, at least a portion of the solder-contacting surface curving from the base portion to the upper portion and defining a tapering solder cavity. A glazing comprising the electrical connector is also disclosed as is a method of soldering the electrical connector to a glazing.

Abstract: This invention relates to a breath indicator that is receivable by a part of a breathing assistance apparatus that supplies gas to a patient. The indicator comprises an elongate body having a gas sampling end and an attachment end. The attachment end is adapted to attach to a part of a breathing assistance apparatus and for locating the gas sampling end. The gas sampling end is to be located in a region where gas from the patient is to be exhaled. The gas sampling end being in communication with a sensor comprising a detector material changeable between a first visual indicator state relating to an inhalation phase of the patient, and a second visual indicator state relating to an exhalation phase of the patient. The detector material is capable of changing between the visual indicator states at a sufficient rate to substantially correspond with the inhalation and exhalation phases of the patient.

Abstract: A patient interface can have a frame supporting a sealing member. Various features of the sealing member can improve comfort and sealing performance in the context of forming seals with the nares of a user, as well as contact with other facial surfaces. The sealing member can include convex portions, concave portions and thickness variations for providing various sealing, comfort, and deformability effects.

Abstract: A method of characterizing candidate agents including steps of (a) providing a library of candidate agents attached to nucleic acid tags; (b) contacting the library with a solid support to attach the candidate agents to the solid support, whereby an array of candidate agents is formed; (c) contacting the array with a screening agent, wherein one or more candidate agents in the array react with the screening agent; (d) detecting the array to determine that at least one candidate agent in the array reacts with the screening agent; (e) sequencing the nucleic acid tag to determine the tag sequences attached to candidate agents in the array; and (f) identifying the at least one candidate agent in the array that reacts with the screening agent based on the tag sequence that is attached to the at least one candidate agent.

Abstract: A method for controlling an energy storage device in an energy storage system includes accessing data stored in a remote cloud storage system where the data including time series data, performing semantic analysis on data accessed in the remote cloud storage system, determining an optimized power cap for a future time of use (TOU) period based on the semantic analysis using an optimization algorithm, and controlling the energy storage device based on the optimized power cap.

Abstract: The present invention relates to compounds of Formula I that function as inhibitors of RET (rearranged during transfection) kinase enzyme activity: wherein HET, bonds a, b, c and d, X1, X2, X3, X4, R2, and R3 are each as defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which RET kinase activity is implicated.

Abstract: A monitoring system includes one or more units that are adapted monitor the radio frequency conditions of a facility or portion of the facility. The units include a packet sniffer and/or an RF spectrum analyzer. Sniffed packets and spectrum data are recorded and made available for analysis and display, either locally on the units or at one or more remote locations. The locations of the units are also gathered, thereby enabling correlation of the sniffed packets and/or RF spectrum data with locations within the facility. Real time RF conditions can thereby be gathered and used to improve the wireless communications within the facility and/or to ensure the wireless communication infrastructure of the facility is operating satisfactorily. The units may be person support apparatuses, such as beds, chairs, stretchers, cots, or the like.

Abstract: There is provided a cable breakout support, comprising a clamp for clamping to a trunking, and a clip for clipping to a cable breakout of a cable bundle supported in the trunking. Each clamp comprises at least two trunk fittings for fitting to at least two respective bulbous longitudinal edges of the trunking; and a clip fitting for connecting to a respective clip.

Abstract: A bendable strap is disclosed which is configured to detachably couple with an accessory. The bendable strap includes a deformable support member covered by a flexible body. A coupling element is secured to the support member and cooperates with a complimentary coupling element disposed on an accessory such as a storage pouch, a tray, a hanger hook, a speaker enclosure, a flashlight, a picture frame, a message board, a bookstand, a beverage holder, or the like.

Abstract: A person support apparatus includes one or more thermal image sensors whose outputs are analyzed to perform one or more functions. Such functions include automatically turning on a brake, automatically turning on one or more lights, detecting when a patient associated with the person support apparatus has fallen, enabling a propulsion system of the patient support apparatus to be used, automatically controlling one or more environmental controls, and/or automatically arming an exit detection system after entry of a patient onto the person support apparatus. Multiple thermal images may be generated from multiple sensors to generate stereoscopic thermal images of portions of the person support apparatus and its surroundings.

Abstract: An airline operations system, controller and method reschedules flights affected by a disruption that precludes a planned schedule for the flights. The method includes obtaining data related to a scheduled origination and a scheduled destination for each of a set of passengers scheduled on the flights, generating a passenger connection network of connections between the scheduled origination and the scheduled destination for a subset of the set of passengers, applying at least one criterion to the passenger connection network and rescheduling at least one connecting flight based on the criteria. The system and controller solves a network flow problem to reschedule a subset of connecting flights to have a delayed projected departure time. Resulting output can include the set of delayed flights along with modified projected departure times, a set of flight cancellations and a set of passengers with missed connections.

Abstract: Systems, computer-implemented methods and/or computer program products that facilitate airline operations and planning management are provided. In one embodiment, a system utilizes a processor that executes computer implemented components stored in memory. A model generation component generates a model of a set of influencers that affect the airline operations. An input component receives data regarding state of a subset of the influencers. An impact component employs the model to determine impact of the state of respective influencers on the airline operations. A scheduling component modifies the airline operations as a function of the determined impact. An update component updates the model to improve model fidelity as a function of collected airline performance data that becomes available after the airline operations have been modified by the scheduling component.