Abstract: The present invention relates to a method for increasing the productivity of 2?-fucosyllactose through various changes in culture medium composition and culturing on the basis of lactose, which is a substrate, wherein 2-fucosyllactose can be continuously produced in a high-yield at an optimum lactose concentration discovered by a culturing method of the present invention.

Abstract: The present invention relates to a method for designing a cycloidal gear tooth profile of a gear shift actuator, the method designing a profile to have a backlash through a change in the radius of a rolling circle of an internal or external tooth profile of a cycloidal gear, and thus enables the smooth engagement of internal teeth and external teeth, reduces the engagement range of the internal teeth and the external teeth to have excellent durability and enable power loss to be reduced, and enables the shape machining of the gear by using general cycloidal gear machining, thereby facilitating manufacturing and being capable of improving machining precision.

Abstract: The present invention relates to stem cell-derived mature cardiomyocytes and a cardiovascular disease model using same and, more specifically, to differentiation into mature ventricular cardiomyocytes by culturing stem cells in a medium containing FGF4 and ascorbic acid, and use of the differentiated mature ventricular cardiomyocytes as a cardiovascular disease cell model. The mature ventricular cardiomyocytes, obtained by culturing stem cells in a medium containing FGF4 and ascorbic acid and inducing the differentiation thereof, and cardiovascular disease cell model using same according to the present invention are very useful for screening for cardiovascular disease therapeutic agents and evaluation of the toxicity of new drugs.

Abstract: A complementary thin film transistor (TFT) includes a substrate and a first TFT and a second TFT disposed on the substrate, wherein a first conductive semiconductor layer of the first TFT and a second gate electrode layer of the second TFT are disposed in the same layer and include the same material.

Abstract: The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit Respiratory Syncytial Virus (RSV). The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from RSV infection. The invention also relates to methods of treating an RSV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

Abstract: The present invention relates to a use of a cell adhesion molecule-related/down-regulated by oncogene (Cdo) protein or a gene encoding the same for preventing or treating neuromuscular diseases caused by damage to motor neurons, particularly muscle stem cells and neuromuscular junctions, due to aging, oxidative stress, and the like; and a method for screening for candidates for activating the expression of Cdo. When Cdo is deleted in motor neurons or neuromuscular junctions, aggravation of damage to degenerative motor neurons due to aging, and DNA damage caused by oxidative stress and inflammation are caused, which may cause neuromuscular diseases. Thus, the diseases can be treated through overexpression and activity of the Cdo protein and the gene encoding the same.

Abstract: Integration methods for prevention of floating gate 3D-NAND cell residual using a hybrid plug process in a super-deck structure and associated apparatus. A first desk layered structure comprising alternating isolation and conductor layers having a top isolation layer is formed over a substrate. A Silicon Nitride (SiN) layer is formed over the top isolation layer. An array of pillar holes vertically passing through the SiN layer and layers in the first deck layered structure are formed. The pillar holes are filled with a sacrificial film and an upper portion of the pillar holes are filled with a hybrid plug comprising first and second oxides. A second layered structure comprising alternating isolation and conductor layers having a bottom isolation layer is formed over the SiN layer, and an array of pillar holes are formed in the second deck layered structure. The hybrid plugs and sacrificial film is then removed using etching.

Abstract: According to one aspect of the present invention, a group account service providing server capable of converting a private account into a group account in real time through a terminal of the host of a comprises: an account management unit configured to convert a first account into a group account when a group account conversion request for the first account of a host of a group is generated; a transaction ledger management unit configured to record change information in a transaction ledger for the group account when the change information including at least one of a transaction occurrence event and an information occurrence event is generated for the group account; a virtual ledger management unit configured to generate a virtual ledger to be mapped to the transaction ledger when the first account is changed to the group account.

Abstract: According to one aspect of the present invention, a group account service providing server capable of converting a private account into a group account in real time through a terminal of the host of a comprises: an account management unit configured to convert a first account into a group account when a group account conversion request for the first account of a host of a group is generated; a transaction ledger management unit configured to record change information in a transaction ledger for the group account when the change information including at least one of a transaction occurrence event and an information occurrence event is generated for the group account; a virtual ledger management unit configured to generate a virtual ledger to be mapped to the transaction ledger when the first account is changed to the group account.

Abstract: An integrated circuit chip includes a substrate on which a standard cell is disposed. The integrated circuit chip includes a plurality of power bumps including a plurality of first power bumps and a plurality of second power bumps, the plurality of power bumps. disposed to have a staggered arrangement in a central region of one surface of the integrated circuit chip, and connected to provide power to the standard cell; a first metal wiring disposed below the plurality of first power bumps and electrically connected to the plurality of first power bumps, at least a part of the first metal wiring overlapping the plurality of first power bumps from a plan view; and a second metal wiring horizontally separated from the first metal wiring, disposed below the plurality of second power bumps, and electrically connected to the plurality of second power bumps, at least a part of the second metal wiring overlapping the plurality of second power bumps from the plan view.

Abstract: The present invention relates to a use for, by using the protein arginine methyltransferase 1 (PRMT1) protein or a gene encoding the same, preventing or treating a neuromuscular disease induced by motor neurons, particularly, damage to motor neurons caused by oxidative stress in the neuromuscular junction; and a method for screening a candidate material for activating the expression of PRMT1. PRMT1 deficiency in the motor nerve or neuromuscular junction induces aggravated degenerative motor nerve damage caused by aging, and DNA damage caused by oxidative stress and inflammation, thereby enabling the induction of neuromuscular disease, and thus the disease may be treated through the overexpression and activity of the PRMT1 protein and a gene encoding the same.

Abstract: A method and system for providing secure data communication between two or more user terminals in a communication network is proposed. The method may include receiving, from a first user terminal, a first instruction set configured to request that a private account be converted into a group account, the private account owned by a user of the first user terminal. The method may also include generating the group account jointly owned by at least the user of the first user terminal and a user of a second user terminal. The method may also include controlling a first database to store a second information set relating to the group account, and generating a second virtual database different from the first database. The method may also include copying the second information set stored in the first database and recording the copied second information set in the second virtual database.

Abstract: A user terminal including a graphical user interface (GUI) for providing secure data communication with a server in a communication network is proposed. The user terminal may include a GUI configured to receive one or more user inputs and display data received from the server. The GUI may include a first screen configured to display a first instruction set for converting a private account to a group account and a second screen configured to display a group account information set received from the server. The user terminal may cause the server to generate the group account, control a first database of the server to store a second information set relating to the group account, generate a second virtual database of the server different from the first database, and copy the second information set stored in the first database and record the copied second information set in the second virtual database.

Abstract: Methods and apparatus for pillar bending improvement by cut tiers pattern implementation. The method uses a cut tier pattern in a staircase region of a 3D memory structure to reduce pillar bending in a pillar array region. The pillar array region includes a plurality of memory tiers comprising wordline layers interposed between isolation layers, where a memory tier comprises a two-dimensional (2D) array of memory cells. A plurality of vertical structures comprising pillars pass through memory cells in the wordline layers and pass through the isolation layers. The staircase structure is disposed adjacent to the pillar array region and includes vertical wordline drivers coupled to the wordline layers. A cut tier pattern comprising vertical trenches is formed in the staircase structure toward a side of the staircase structure adjacent to the pillar array region. The cut tier pattern includes one or more breaks used for routing circuitry in the wordlines.

Abstract: A dynamic fault clustering method and apparatus for efficiently managing redundancy in semiconductor memories performs a collection operation of searching for and detecting a fault and an operation of appropriately clustering the fault at the same time, which reduces an amount of time spent performing Built-In Redundancy Analysis (BIRA).

Abstract: A redundancy managing method and apparatus for semiconductor memories is disclosed. The redundancy managing method for semiconductor memories utilizes bitmap type storage by defining an appropriate storage space according to the type of a fault.

Abstract: Disclosed are an ultrasonic probe and a method of manufacturing the same. The ultrasonic probe includes a piezoelectric layer including one or more kerfs such that piezoelectric elements are provided in a plurality of rows along an elevation direction, a first electrode formed on an upper side of the piezoelectric layer, a second electrode formed on a lower side of the piezoelectric layer, a matching layer disposed above the piezoelectric layer and including one or more grooves connected to the one or more kerfs, and a third electrode formed in inner surfaces of the one or more grooves and electrically connected to the first electrode.

Abstract: Provided is a heater assembly for aerosol generating devices, the heater assembly including a thermally conductive element that has a cylindrical shape and includes an accommodation space for accommodating a cigarette, a flexible heater that surrounds at least a portion of an outer surface of the thermally conductive element, and an adhesion member that surrounds the flexible heater such that the flexible heater closely adheres to the thermally conductive element.

Abstract: The present disclosure relates to a nucleic acid analysis apparatus using a cartridge which can simplify the nucleic acid extraction and applicable to a molecular diagnostic POCT equipment. The nucleic acid analysis device includes a stage on which a cartridge is mountable, a nucleic acid extraction unit, and a control unit. The nucleic acid extraction unit performs a nucleic acid extraction through crushing of the sample, the cell disruption, and the nucleic acid purification as well as a nucleic acid amplification. The control unit controls the stage and the nucleic acid extraction unit so that the nucleic acid extraction through the crushing of the sample, the cell disruption, and the nucleic acid purification as well as the nucleic acid amplification are collectively performed.

Abstract: Provided is a heater assembly for aerosol generating devices, the heater assembly including a thermally conductive element that has a cylindrical shape and includes an accommodation space for accommodating a cigarette, a flexible heater that surrounds at least a portion of an outer surface of the thermally conductive element, and an adhesion member that surrounds the flexible heater such that the flexible heater closely adheres to the thermally conductive element.