Patents by Inventor Jorge Bernate

Jorge Bernate has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INSTRUMENTS, MODULES, AND METHODS FOR IMPROVED DETECTION OF EDITED SEQUENCES IN LIVE CELLS
    Publication number: 20200087613
    Abstract: The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods—including high throughput methods—for screening cells that have been subjected to editing and identifying cells that have been properly edited.
    Type: Application
    Filed: November 25, 2019
    Publication date: March 19, 2020
    Inventors: Phillip Belgrader, Don Masquelier, Bruce Chabansky, Jorge Bernate, Andrew Garst, Richard Fox
  • AUTOMATED CELL PROCESSING METHODS, MODULES, INSTRUMENTS, AND SYSTEMS
    Publication number: 20200080078
    Abstract: In an illustrative embodiment, automated multi-module cell editing instruments are provided to automate multiple edits into nucleic acid sequences inside one or more cells.
    Type: Application
    Filed: November 12, 2019
    Publication date: March 12, 2020
    Inventors: Don Masquelier, Phillip Belgrader, Jorge Bernate, Ryan Gill, Kevin Ness
  • AUTOMATED CELL GROWTH AND/OR CONCENTRATION MODULES AS STAND-ALONE DEVICES OR FOR USE IN MULTI-MODULE CELL PROCESSING INSTRUMENTATION
    Publication number: 20200080045
    Abstract: The present disclosure provides a cell growth, buffer exchange, and/or cell concentration/filtration device that may be used as a stand-alone device or as a module configured to be used in an automated multi-module cell processing environment.
    Type: Application
    Filed: September 5, 2019
    Publication date: March 12, 2020
    Inventors: Jorge Bernate, Don Masquelier, Phillip Belgrader, Bruce Chabansky
  • Automated cell processing methods, modules, instruments, and systems
    Patent number: 10584333
    Abstract: In an illustrative embodiment, automated multi-module cell editing instruments are provided to automate multiple edits into nucleic acid sequences inside one or more cells.
    Type: Grant
    Filed: October 29, 2019
    Date of Patent: March 10, 2020
    Assignee: Inscripta, Inc.
    Inventors: Don Masquelier, Phillip Belgrader, Jorge Bernate, Ryan Gill, Kevin Ness
  • Automated cell processing methods, modules, instruments, and systems
    Patent number: 10584334
    Abstract: In an illustrative embodiment, automated multi-module cell editing instruments are provided to automate multiple edits into nucleic acid sequences inside one or more cells.
    Type: Grant
    Filed: November 12, 2019
    Date of Patent: March 10, 2020
    Assignee: Inscripta, Inc.
    Inventors: Don Masquelier, Phillip Belgrader, Jorge Bernate, Ryan Gill, Kevin Ness
  • Automated cell processing instruments comprising reagent cartridges
    Patent number: 10576474
    Abstract: The present disclosure provides a reagent cartridge configured for use in an automated multi-module cell processing environment.
    Type: Grant
    Filed: October 9, 2019
    Date of Patent: March 3, 2020
    Assignee: Inscripta, Inc.
    Inventors: Don Masquelier, Phillip Belgrader, Brian Van Hatten, Jorge Bernate, Bruce Chabansky
  • AUTOMATED CELL PROCESSING METHODS, MODULES, INSTRUMENTS, AND SYSTEMS
    Publication number: 20200063123
    Abstract: In an illustrative embodiment, automated multi-module cell editing instruments are provided to automate multiple edits into nucleic acid sequences inside one or more cells.
    Type: Application
    Filed: October 29, 2019
    Publication date: February 27, 2020
    Inventors: Don Masquelier, Phillip Belgrader, Jorge Bernate, Ryan Gill, Kevin Ness
  • Automated nucleic acid assembly and introduction of nucleic acids into cells
    Patent number: 10557150
    Abstract: In an illustrative embodiment, automated instruments comprising one or more flow-through electroporation devices or modules are provided to automate transformation of nucleic acids in live cells.
    Type: Grant
    Filed: September 14, 2019
    Date of Patent: February 11, 2020
    Assignee: Inscripta, Inc.
    Inventors: Jorge Bernate, Don Masquelier, Phillip Belgrader
  • AUTOMATED CELL PROCESSING INSTRUMENTS COMPRISING REAGENT CARTRIDGES
    Publication number: 20200038874
    Abstract: The present disclosure provides a reagent cartridge configured for use in an automated multi-module cell processing environment.
    Type: Application
    Filed: October 9, 2019
    Publication date: February 6, 2020
    Inventors: Don Masquelier, Phillip Belgrader, Brian Van Hatten, Jorge Bernate, Bruce Chabansky
  • Instruments, modules, and methods for improved detection of edited sequences in live cells
    Patent number: 10533152
    Abstract: The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods—including high throughput methods—for screening cells that have been subjected to editing and identifying cells that have been properly edited.
    Type: Grant
    Filed: April 30, 2019
    Date of Patent: January 14, 2020
    Assignee: Inscripta, Inc.
    Inventors: Phillip Belgrader, Don Masquelier, Bruce Chabansky, Jorge Bernate, Andrew Garst, Richard Fox
  • Automated cell processing methods, modules, instruments, and systems
    Patent number: 10519437
    Abstract: In an illustrative embodiment, automated multi-module cell editing instruments are provided to automate multiple edits into nucleic acid sequences inside one or more cells.
    Type: Grant
    Filed: September 14, 2019
    Date of Patent: December 31, 2019
    Assignee: Inscripta, Inc.
    Inventors: Don Masquelier, Phillip Belgrader, Jorge Bernate, Ryan Gill, Kevin Ness
  • AUTOMATED NUCLEIC ACID ASSEMBLY AND INTRODUCTION OF NUCLEIC ACIDS INTO CELLS
    Publication number: 20190382795
    Abstract: In an illustrative embodiment, automated instruments comprising one or more flow-through electroporation devices or modules are provided to automate transformation of nucleic acids in live cells.
    Type: Application
    Filed: August 22, 2019
    Publication date: December 19, 2019
    Inventors: Jorge Bernate, Don Masquelier, Phillip Belgrader
  • Automated cell processing methods, modules, instruments, and systems comprising flow-through electroporation devices
    Patent number: 10508288
    Abstract: In an illustrative embodiment, automated multi-module cell editing instruments comprising one or more flow-through electroporation devices or modules are provided to automate genome editing in live cells.
    Type: Grant
    Filed: September 14, 2019
    Date of Patent: December 17, 2019
    Assignee: Inscripta, Inc.
    Inventors: Jorge Bernate, Don Masquelier, Phillip Belgrader, Kevin Ness
  • MODIFICATION OF CELLS BY INTRODUCTION OF EXOGENOUS MATERIAL
    Publication number: 20190376085
    Abstract: The present disclosure provides methods and devices for rapid and efficient modification of a variety of cell types, including mammalian cells, plant cells, archaea, yeasts, and bacteria, by novel methods of introducing exogenous materials, e.g. nucleic acids.
    Type: Application
    Filed: August 26, 2019
    Publication date: December 12, 2019
    Inventors: Jorge Bernate, Don Masquelier
  • AUTOMATED CELL PROCESSING INSTRUMENTS COMPRISING REAGENT CARTRIDGES
    Publication number: 20190351421
    Abstract: The present disclosure provides a reagent cartridge configured for use in an automated multi-module cell processing environment.
    Type: Application
    Filed: July 29, 2019
    Publication date: November 21, 2019
    Inventors: Don Masquelier, Phillip Belgrader, Brian Van Hatten, Jorge Bernate, Bruce Chabansky
  • Automated cell processing instruments comprising reagent cartridges
    Patent number: 10478822
    Abstract: The present disclosure provides a reagent cartridge configured for use in an automated multi-module cell processing environment.
    Type: Grant
    Filed: July 29, 2019
    Date of Patent: November 19, 2019
    Assignee: Inscripta, Inc.
    Inventors: Don Masquelier, Phillip Belgrader, Brian Van Hatten, Jorge Bernate, Bruce Chabansky
  • Automated cell processing methods, modules, instruments, and systems
    Patent number: 10465185
    Abstract: In an illustrative embodiment, automated multi-module cell editing instruments are provided to automate multiple edits into nucleic acid sequences inside one or more cells.
    Type: Grant
    Filed: May 28, 2019
    Date of Patent: November 5, 2019
    Assignee: Inscripta, Inc.
    Inventors: Don Masquelier, Phillip Belgrader, Jorge Bernate, Ryan Gill, Kevin Ness
  • AUTOMATED CELL PROCESSING METHODS, MODULES, INSTRUMENTS, AND SYSTEMS
    Publication number: 20190316120
    Abstract: In an illustrative embodiment, automated multi-module cell editing instruments are provided to automate multiple edits into nucleic acid sequences inside one or more cells.
    Type: Application
    Filed: May 28, 2019
    Publication date: October 17, 2019
    Inventors: Don Masquelier, Phillip Belgrader, Jorge Bernate, Ryan Gill, Kevin Ness
  • Modification of cells by introduction of exogenous material
    Patent number: 10443074
    Abstract: The present disclosure provides methods and devices for rapid and efficient modification of a variety of cell types, including mammalian cells, plant cells, archaea, yeasts, and bacteria, by novel methods of introducing exogenous materials, e.g. nucleic acids.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: October 15, 2019
    Assignee: Inscripta, Inc.
    Inventors: Jorge Bernate, Don Masquelier
  • Flow through electroporation instrumentation
    Patent number: 10435713
    Abstract: The present disclosure provides a flow-through electroporation device configured for use as a stand-alone module or as one module in an automated multi-module processing system.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: October 8, 2019
    Assignee: Inscripta, Inc.
    Inventors: Jorge Bernate, Don Masquelier