Abstract: There is provided a system, apparatus and methods for developing laser systems that can create precise predetermined clear corneal incisions that are capable of reducing induced astigmatism. The systems, apparatus and methods further provide laser systems that can provide these incisions at or below Bowman's membrane.

Abstract: An orthopedic implant adapted for fastening to a bone by use of a screw, the implant comprising a plate composed of a biocompatible material and a hole defining an internal hole wall and having an innermost surface; the hole adapted to receive said screw; the internal hole wall comprising a primary inner width and a secondary outer width with a distance therebetween defining a volume; the volume comprising a biocompatible material and a plurality of blind holes extending from the primary inner width to the secondary outer width resulting in a porosity; wherein the internal hole wall comprises a non-helical pattern. In at least one embodiment, 30% to 70% of the volume is comprised of the biocompatible material and the remaining 70% to 30% of the volume is devoid of any material. In another embodiment, the porosity of the volume is between 0.3 and 0.7.

Abstract: A guidance system, a method and a device for dynamically guiding a surgical needle catheter onto an organ to be surgically operated of a patient. In particular, the disclosure relates to a guidance system, a method and a device to aid in the percutaneous kidney puncture.

Abstract: Described herein are methods of treating symptoms of neurodegenerative disorders using palmidrol and a cannabinoid.

Abstract: A subject matter of the present invention is system, method, and computer readable medium configured to synthesize a drug product. Single-step organic-chemistry reactions are provided as inputs to a first machine learning model. At least one synthetic route to a product is determined based on an output of the first machine learning model. A score for each of the at least one synthetic route is determined. The at least one synthetic route and its respective score are provided as inputs to a second machine learning model. At least one qualified route is determined based on an output of the second machine learning model.

Abstract: A supported silver catalyst and use thereof in a process for producing an olefin oxide, such as ethylene oxide, by the direct oxidation of an alkylene with oxygen or an oxygen-containing gas, wherein the catalyst provides good catalyst activity and/or efficiency despite loading levels of silver in the range of 16 to 25%.

Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH011181. The invention thus relates to the plants, seeds and tissue cultures of the variety CH011181, and to methods for producing a corn plant produced by crossing a corn plant of variety CH011181 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH011181.

Abstract: The disclosure relates to a method of making a bioceramic coating on a fibrous article for use in a medical implant, comprising steps of providing an article comprising fibers made from a biocompatible, non-biodegradable polymer; coating at least the fibers that will be in contact with bone upon use as an implant with a solution of a coating polymer to result in coated fibers having a coating polymer layer; treating the coated fibers with a dispersion of bioactive ceramic particles 0.01-10 ?m in a treating solvent comprising a solvent for the coating polymer in at least one step; and substantially removing the treating solvent; to result in the particles being partly embedded in the coating polymer layer of the coated fibers.

Abstract: Disclosed are systems and methods for providing automated or semi-automated technical support for patients using medical devices, such as continuous glucose monitoring systems. Disclosed embodiments of automated tech support system include collection and storage of copies of streams of medical device data on multiple servers, analysis and comparison of data streams, remote tech support initiation and usage of the automated tech support system for providing improved products and services by storing and analyzing historical tech support data.

Abstract: A control system is for a railway yard with railroad tracks. The control system may include RCLs and sets of railcars on the railroad tracks. The control system may include railyard sensors configured to generate railyard sensor data of the railroad tracks, and a server in communication with the RCLs and the railyard sensors. The server may be configured to generate a database associated with the sets of railcars based upon the railyard sensor data. The database may have, for each railcar, a railcar type value, a railcar logo image, and a vehicle classification value. The server may be configured to selectively control the RCLs to position the sets of railcars within the railroad tracks based upon the railyard sensor data.

Abstract: A system comprising a microcontroller located on a communication bus, a power consumption circuit configured to determine power consumption of the microcontroller, wherein a processor is programmed to determine if a clock associated with the microcontroller is paused and whether an average operational power has exceeded a power threshold, and in response to the average operational power exceeding the power threshold and in response to identifying an attacked message or attacked electronics control unit, in response to determining the microcontroller is under the suspected attack, output an alert associated with an event causing change in the bit patterns of messages on the communication bus.

Abstract: A combined plant for cryogenic separation and liquefaction of methane and carbon dioxide in a biogas stream, including a mixing means, a compressor, a first exchanger, a distillation column, a second exchanger, a separating means, an expanding means, and a separator vessel. Wherein, the mixing means is configured such that the recycle gas is the overhead vapour stream, and the first exchanger and the expanding means are combined.

Abstract: The present invention relates to a device for exercising the pelvic floor muscles in women, which comprises a main component (A), a secondary component (B) and a set of external weights (P). Component (A) is directly related to pelvic floor muscle contraction exercise. Component (B) allows the evaluation and monitoring of contraction exercises by measuring the displacement of a rod on a graduated ruler. The set of weights (P), with different loads, allows it to impose resistance of different magnitudes on the muscle exercises to be performed, according to the user's needs and objectives. Thus, this invention falls within the technical field of mechanical functioning devices, with application to the medical area, for the treatment and/or prevention of pathological situations related to the alteration of the muscular function of the pelvic floor region.

Abstract: Systems and methods are described herein for reducing electromagnetic interference (EMI) affecting measurements of a battery module monitoring board. A battery module system includes battery cells on a top side and a bottom side of the battery module. Each battery cell is electrically coupled between an adjacent pair of busbars. Each busbar is coupled to at least one sensor wire. One busbar, which spans the top and bottom sides of the battery module, is coupled to two sensor wires such that EMI interference affecting measurement signals (e.g., noise signals accompanying voltage readings) associated with the top side of the battery module are in-phase with one another and the measurement signals associated with the bottom side of the battery module are in-phase with one another, such that the EMI interference generally cancels in measurement calculations.

Abstract: Some embodiments provide a mapping application that provides a variety of UI elements for allowing a user to specify a location (e.g., for viewing or serving as route destinations). In some embodiments, these location-input UI elements appear in succession on a sequence of pages, according to a hierarchy that has the UI elements that require less user interaction appear on earlier pages in the sequence than the UI elements that require more user interaction. In some embodiments, the location-input UI elements that successively appear in the mapping application include (1) selectable predicted-destination notifications, (2) a list of selectable predicted destinations, (3) a selectable voice-based search affordance, and (4) a keyboard.

Abstract: Systems, methods, and computer-readable media are disclosed for performing a hitless upgrade of executable code in the absence of an orchestrator or other upgrade manager. A mechanism is disclosed that utilizes containers to update software functionality, features, or the like without interrupting a service provided by a container and without relying on an orchestrator or other upgrade manager to coordinate the upgrade process. State information indicative of a current state of module(s) within a container is maintained in an external data store such as a state database. A hand-off from a current container to a new container that updates module code/functionality of the current container can be initiated upon determining that a state metric calculated by the old container at a future timestamp matches a state metric independently calculated by the new container at the same timestamp.

Abstract: Disclosed are multi-ply embossed tissue products having improved softness, strength, embossment clarity and/or embossment height compared to prior art embossed tissue products. The multi-ply tissue products may comprise an embossed tissue ply having a basis weight less than about 25 grams per square meter (gsm) and relatively deep embossments, such as an embossment height from about 500 to about 1,000 ?m and relatively narrow bottom portions compared to top portions. The combination of these elements provides an aesthetically pleasing and well-defined embossment, while improving important tissue product properties such as sheet and roll bulk and softness.

Abstract: Methods and systems are provided for a battery exchange station for an electric vehicle. In one example, a battery exchange station may include a vehicle platform including one or more lifters, a first storage rack positioned on a first side of the vehicle platform, and a second storage rack positioned on an opposing, second side of the vehicle platform. The first storage rack and the second storage rack may store a plurality of batteries. The battery exchange station may include a battery exchange mechanism comprising a dual component battery chamber, a first mobile table, and a second mobile table, the dual component battery chamber comprising stationary component fixed to the electric vehicle and a mobile component slideably coupled to the stationary component, wherein the mobile component is released from the stationary component when the electric vehicle is directly on the vehicle platform and lifted via the one or more lifters.

Abstract: Disclosed are methods for making a vascularized hollow organ derived from human intestinal organoid (HIOs). The HIOs may be obtained from human embryonic stem cells (ESC's) and/or induced pluripotent stem cells (iPSCs), such that the HIO forms mature intestinal tissue. Also disclosed are methods for making a human intestinal tissue containing a functional enteric nervous system (ENS).

Abstract: Method and system for distributing sensor data, the method comprising the steps of recording data from one or more sensors of a device. Digitally signing the data or information derived from the data within a UICC of the device using a private key of a private and public key pair stored within the UICC of the device. Authenticating the digitally signed data or information derived from the data by a server. Triggering, by the authenticated data or information derived from the data, an entry into a distributed ledger identifying the data or information derived from the data. Receiving a request from a requester for the data or information derived from the data in response to the entry within the distributed ledger. Transmitting the data or information derived from the data from the device to the requester.