Patents by Inventor Jorgen Hansen

Jorgen Hansen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and materials for biosynthesis of mogroside compounds
    Patent number: 10633685
    Abstract: Methods for recombinant and enzymatic production of mogroside compounds and compositions containing mogroside compounds are provided by this invention.
    Type: Grant
    Filed: September 30, 2015
    Date of Patent: April 28, 2020
    Assignee: EVOLVA SA
    Inventors: Jens Houghton-Larsen, Katarzyna Krzystanek, Angelika Semmler, Iver Klavs Riishede Hansen, Soren Damkiaer, Yaoquan Liu, Jorgen Hansen, Sathish Kumar, Muthuswamy Panchapagesa Murali, Nina Nicoline Rasmussen
  • Recombinant Production of Steviol Glycosides
    Publication number: 20200123583
    Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express recombinant genes encoding UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce steviol glycosides, e.g., Rebaudioside A and/or Rebaudioside D, which can be used as natural sweeteners in food products and dietary supplements.
    Type: Application
    Filed: August 8, 2019
    Publication date: April 23, 2020
    Inventors: Jens Houghton-Larsen, Paula Hicks, Michael Naesby, Thomas Tange Ostergaard, Jorgen Hansen, Michael Mikkelsen Dalgaard, Esben Hansen Halkjaer, Ernesto Simon, Sabina Tavares
  • Methods for improved production of rebaudioside D and rebaudioside M
    Patent number: 10612066
    Abstract: Methods for recombinant production of steviol glycoside and compositions containing steviol glycosides are provided by this invention.
    Type: Grant
    Filed: February 28, 2018
    Date of Patent: April 7, 2020
    Assignee: Evolva SA
    Inventors: Michael Dalgaard Mikkelsen, Jorgen Hansen, Ernesto Simon, Federico Brianza, Angelika Semmler, Kim Olsson, Simon Carlsen, Louis Düring, Alexei Ouspenski, Paula Hicks
  • Methods and materials for biosynthesis of mogroside compounds
    Patent number: 10465222
    Abstract: The invention relates to methods for producing mogrosides with the aid of enzymes. In particular the invention proposes various biosynthetic pathways useful for mogroside production and enzymes useful for mogroside production are provided. Furthermore, the invention provides recombinant hosts useful in performing the methods of the invention.
    Type: Grant
    Filed: May 8, 2018
    Date of Patent: November 5, 2019
    Assignee: EVOLVA SA
    Inventors: Yaoquan Liu, Jorgen Hansen, Jens Houghton-Larsen, Muthuswamy Panchapagesa Murali, Sathish Kumar, Nina Nicoline Rasmussen
  • Recombinant production of steviol glycosides
    Patent number: 10435730
    Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express recombinant genes encoding UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce steviol glycosides, e.g., Rebaudioside A and/or Rebaudioside D, which can be used as natural sweeteners in food products and dietary supplements.
    Type: Grant
    Filed: February 22, 2017
    Date of Patent: October 8, 2019
    Assignee: EVOLVA SA
    Inventors: Jens Houghton-Larsen, Paula Hicks, Michael Naesby, Thomas Tange Ostergaard, Jorgen Hansen, Michael Mikkelsen Dalgaard, Esben Hansen Halkjaer, Ernesto Simon, Sabina De Andrade Periera Tavares
  • Remote direct memory access in a virtualized computing environment
    Patent number: 10417174
    Abstract: A method of managing remote direct memory access (RDMA) to a virtual computing instance includes suspending locally initiated RDMA operations of the virtual computing instance executing on a first host prior to a migration of the virtual computing instance to a second host. The first host includes a first hypervisor and the second host includes a second hypervisor. The method further includes requesting a peer to suspend remotely initiated RDMA operations that target the virtual computing instance through a first channel, establishing after the migration, a second channel between the peer and the second hypervisor that supports execution of the virtual computing instance on the second host, configuring a virtual object of the second hypervisor on the second host to use the second channel for the locally initiated RDMA operations, and requesting the peer to resume the remotely initiated RDMA operations using the second channel.
    Type: Grant
    Filed: June 24, 2016
    Date of Patent: September 17, 2019
    Assignee: VMware, Inc.
    Inventors: Adit Ranadive, Aditya Sarwade, Andy King, Jorgen Hansen, Bhavesh Davda, George Zhang, Xiaoyun Gong
  • Production of steviol glycosides in microorganisms
    Patent number: 10392644
    Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express novel recombinant genes encoding steviol biosynthetic enzymes and UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce steviol or steviol glycosides, e.g., rubusoside or Rebaudioside A, which can be used as natural sweeteners in food products and dietary supplements.
    Type: Grant
    Filed: December 16, 2016
    Date of Patent: August 27, 2019
    Assignee: EVOLVA SA
    Inventors: Ganesh M. Kishore, Jorgen Hansen, Jens Houghton-Larsen, Esben Halkjaer Hansen, Michael Dalgaard Mikkelsen, Sabina Tavares, Charlotte Blom
  • PRODUCTION OF CITRONELLAL AND CITRONELLOL IN RECOMBINANT HOSTS
    Publication number: 20190225945
    Abstract: The invention relates to recombinant microorganisms and methods of producing citronellal, citronellol, citronellic acid, and/or citronellal/citronellol pathway intermediates and precursors.
    Type: Application
    Filed: October 11, 2017
    Publication date: July 25, 2019
    Inventors: Thomas Oestergaard Tange, Johannes Haerle, Fanny Delegrange, Julien Denis Vivian De Block, Robert Charles Allan, Philipp Friedrich Berninger, Christophe Folly, Davide Antonio Ravasio, Ludivine Labagnere, Federico Brianza, Curt Aimé Friis Nielsen, Jørgen Hansen, Nora Weber, Samantha Jessica Capewell
  • METHODS FOR IMPROVED PRODUCTION OF REBAUDIOSIDE D AND REBAUDIOSIDE M
    Publication number: 20190203243
    Abstract: Methods for recombinant production of steviol glycoside and compositions containing steviol glycosides are provided by this invention.
    Type: Application
    Filed: February 28, 2018
    Publication date: July 4, 2019
    Inventors: Michael Dalgaard Mikkelsen, Jorgen Hansen, Ernesto Simon, Federico Brianza, Angelika Semmler, Kim Olsson, Simon Carlsen, Louis Düring, Alexei Ouspenski, Paula Hicks
  • Production of Glycosylated Melanin Precursors in Recombinant Hosts
    Publication number: 20190106722
    Abstract: The invention relates to methods for producing melanin and melanin precursors, derivatives, and intermediates. In particular, recombinant microorganisms are disclosed that express tyrosinases to produce 5,6-DHI and express UGT polypeptides capable of either in vivo or in vitro glycosylation of melanin precursors, derivatives, and intermediates. Glycosylated 5,6-DHI is produced both in vivo and in vitro.
    Type: Application
    Filed: April 12, 2017
    Publication date: April 11, 2019
    Inventors: Laura Occhipinti, Yiming Chang, Jorgen Hansen
  • Production of Steviol Glycosides in Microorganisms
    Publication number: 20190078128
    Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express novel recombinant genes encoding steviol biosynthetic enzymes and UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce steviol or steviol glycosides, e.g., rubusoside or Rebaudioside A, which can be used as natural sweeteners in food products and dietary supplements.
    Type: Application
    Filed: December 16, 2016
    Publication date: March 14, 2019
    Inventors: Ganesh M. KISHORE, Michael MOTION, Paula M. HICKS, Jorgen HANSEN, Jens HOUGHTON-LARSEN, Esben Halkjaer HANSEN, Michael Dalgaard MIKKELSEN, Sabina TAVARES, Charlotte BLOM
  • Efficient Production of Steviol Glycosides in Recombinant Hosts
    Publication number: 20180371517
    Abstract: Recombinant microorganisms are disclosed that produce steviol glycosides and have altered expression of one or more endogenous transporter or transcription factor genes or that overexpress one or more heterologous transporters, leading to increased excretions of steviol glucosides of interest.
    Type: Application
    Filed: June 7, 2018
    Publication date: December 27, 2018
    Inventors: Ernesto Simon, Iben Nordmark Anderson, Michael Dalgaard Mikkelsen, Jorgen Hansen, Veronique Douchin
  • Methods and materials for Biosynthesis of Mogroside Compounds
    Publication number: 20180346953
    Abstract: The invention relates to methods for producing mogrosides with the aid of enzymes. In particular the invention proposes various biosynthetic pathways useful for mogroside production and enzymes useful for mogroside production are provided. Furthermore, the invention provides recombinant hosts useful in performing the methods of the invention.
    Type: Application
    Filed: May 8, 2018
    Publication date: December 6, 2018
    Inventors: Yaoquan Liu, Jorgen Hansen, Jens Houghton-Larsen, Muthuswamy Panchapagesa Murali, Sathish Kumar, Nina Nicoline Rasmussen
  • Production of Glycosylated Nootkatol in Recombinant Hosts
    Publication number: 20180327723
    Abstract: The invention relates to methods for producing glycosylated nootkatol. In particular, a recombinant host comprising a gene encoding a UDP-glycosyltransferase polypeptide capable of glycosylating nootkatol is disclosed. Glycosylation of nootkatol detoxifies nootkatol, allowing for greater production of (glycosylated-)nootkatol, a precursor of nootkatone, and therefore greater production of nootkatone. The invention also relates to methods of converting non-toxic, glycosylated nootkatol produced by a recombinant host to nootkatol, wherein the nootkatol can subsequently be converted to large quantities of nootkatone to be used in flavorings, perfumes, and/or insect repellents.
    Type: Application
    Filed: November 14, 2016
    Publication date: November 15, 2018
    Inventors: Dayal Saran, Jorgen Hansen, Philippe Prochasson, Patrick Roussel, Laura Occhipinti, Alexei Ouspenski, Sumire Honda Malca
  • Anthocyanins with specific properties
    Patent number: 10119154
    Abstract: The present disclosure provides methods for identifying anthocyanins with improved stability, color, or hue using a screening method, and producing anthocyanins with improved stability, color, or hue in, for example, host cells comprising one or more heterologous glycosyltransferase nucleic acid molecules and one or more heterologous acyltransferase nucleic acid molecules.
    Type: Grant
    Filed: December 23, 2013
    Date of Patent: November 6, 2018
    Assignee: Evolva SA
    Inventors: Jorgen Hansen, Patricia Hoyle, Michael Naesby, Joseph M. Sheridan, Jonathan R. Heal
  • Methods and Materials for Biosynthesis of Mogroside Compounds
    Publication number: 20180251806
    Abstract: The invention relates to methods for producing mogrosides with the aid of enzymes. In particular the invention proposes various biosynthetic pathways useful for mogroside production and enzymes useful for mogroside production are provided. Furthermore, the invention provides recombinant hosts useful in performing the methods of the invention.
    Type: Application
    Filed: February 20, 2018
    Publication date: September 6, 2018
    Inventors: Yaoquan Liu, Jorgen Hansen, Jens Houghton-Larsen, Muthuswamy Panchapagesa Murali, Sathish Kumar, Nina Nicoline Rasmussen
  • Efficient production of steviol glycosides in recombinant hosts
    Patent number: 10017804
    Abstract: Recombinant microorganisms are disclosed that produce steviol glycosides and have altered expression of one or more endogenous transporter or transcription factor genes, or that overexpress one or more heterologous transporters, leading to increased excretion of steviol glycosides of interest.
    Type: Grant
    Filed: February 11, 2014
    Date of Patent: July 10, 2018
    Assignee: EVOLVA SA
    Inventors: Ernesto Simon, Iben Nordmark Anderson, Michael Dalgaard Mikkelsen, Jorgen Hansen, Veronique Douchin
  • Methods and materials for biosynthesis of mogroside compounds
    Patent number: 10011859
    Abstract: The invention relates to methods for producing mogrosides with the aid of enzymes. In particular the invention proposes various biosynthetic pathways useful for mogroside production and enzymes useful for mogroside production are provided. Furthermore, the invention provides recombinant hosts useful in performing the methods of the invention.
    Type: Grant
    Filed: October 1, 2014
    Date of Patent: July 3, 2018
    Assignee: EVOLVA SA
    Inventors: Yaoquan Liu, Jorgen Hansen, Jens Houghton-Larsen, Muthuswamy Panchapagesa Murali, Sathish Kumar, Nina Nicoline Rasmussen
  • Methods for improved production of Rebaudioside D and Rebaudioside M
    Patent number: 9957540
    Abstract: Methods for recombinant production of steviol glycoside and compositions containing steviol glycosides are provided herein.
    Type: Grant
    Filed: February 6, 2014
    Date of Patent: May 1, 2018
    Assignee: EVOLVA SA
    Inventors: Michael Dalgaard Mikkelsen, Jorgen Hansen, Ernesto Simon, Federico Brianza, Angelika Semmler, Kim Olsson, Simon Carlsen, Louis Düring, Alexei Ouspenski, Paula Hicks
  • Methods and materials for biosynthesis of mogroside compounds
    Patent number: 9932619
    Abstract: The invention relates to methods for producing mogrosides with the aid of enzymes. In particular the invention proposes various biosynthetic pathways useful for mogroside production and enzymes useful for mogroside production are provided. Furthermore, the invention provides recombinant hosts useful in performing the methods of the invention.
    Type: Grant
    Filed: December 4, 2013
    Date of Patent: April 3, 2018
    Assignee: EVOLVA SA
    Inventors: Yaoquan Liu, Jorgen Hansen, Jens Houghton-Larsen, Muthuswamy Panchapagesa Murali, Sathish Kumar, Nina Nicoline Rasmussen