Abstract: Protected sensor field effect transistors (SFETs). The SFETs include a semiconductor substrate, a field effect transistor, and a sense electrode. The SFETs further include an analyte-receiving region that is supported by the semiconductor substrate, is in contact with the sense electrode, and is configured to receive an analyte fluid. The analyte-receiving region is at least partially enclosed. In some embodiments, the analyte-receiving region can be an enclosed analyte channel that extends between an analyte inlet and an analyte outlet. In these embodiments, the enclosed analyte channel extends such that the analyte inlet and the analyte outlet are spaced apart from the sense electrode. In some embodiments, the SFETs include a cover structure that at least partially encloses the analyte-receiving region and is formed from a cover material that is soluble within the analyte fluid. The methods include methods of manufacturing the SFETs.

Abstract: The present disclosure relates to a process for manufacturing 2,3-butanediol by electroreduction of 3-hydroxybutan-one in an aqueous media.

Abstract: An organomimetic device includes a microfluidic device that can be used to culture cells in its microfluidic channels. The organomimetic device can be part of dynamic system that can apply mechanical forces to the cells by modulating the microfluidic device and the flow of fluid through the microfluidic channels. The membrane in the organomimetic device can be modulated mechanically via pneumatic means and/or mechanical means. The organomimetic device can be manufactured by the fabrication of individual components separately, for example, as individual layers that can be subsequently laminated together.

Abstract: A machine, program product, and method for enabling interoperable and low-latency networking among service devices.

Abstract: EHT extract including a mixture of late eluting tryptamides and early eluting tryptamides in a weight ratio of at least about 7:1 late eluting tryptamides:early eluting tryptamides, wherein the EHT extract includes at least 30% eicosanoyl-5-hydroxytryptamide, based on the total weight of the tryptamides in the EHT extract.

Abstract: Compositions containing natural and botanical extracts for use in inhibiting one, two, or three of (a)-(c): (a) demethylation of PP2A by PME-1 methylesterase; (b) formation of free radicals and reactive oxygen species; and/or (c) inflammation. These compositions include an extract of one or more botanicals selected from the group consisting of: juniper berry fruit, schisandra fruit, strawberry fruit, avocado seeds, black raspberry seeds, blueberry seeds, celery seeds, cranberry seeds, fennel seeds, grape seeds, guarana seeds, red raspberry seeds, maca root, goldenseal root, turmeric root, magnolia bark, pygeum bark, red raspberry leaf, almond, cocoa powder, Echinacea angustifolia, prickly pear cactus and walnut.

Abstract: A highly efficient LED lighting fixture includes a plurality of LEDs and a power converter and control circuit. The power converter circuit is a non-isolated power converter circuit. A heat sink is thermally coupled to a circuit board that carries the power converter, and an AC powered fan directs air over the heat sink to remove heat from the circuit board. The LED lighting fixture has an efficacy of at least 70 lm/w.

Abstract: A drill system for forming a curved tunnel in a bone includes a drill bit guidance device. The drill bit guidance device includes an elongated stationary outer tube extending along a first axis and an elongated inner tube. The elongated inner tube is configured to slidably move within the elongated stationary outer tube along the first axis and to exit from a distal end of the elongated outer tube. The elongated inner tube has a partially slotted distal end portion including a plurality of semi-cross-sectional slots extending perpendicular to the first axis. Each slot is configured to collapse inward in the slot direction when exiting the distal end of the elongated outer tube, thereby curving the distal end portion of the elongated inner tube.

Abstract: A machine, program product, and method for enabling interoperable and low-latency networking among service devices.

Abstract: A car panel for an elevator car, a method for assembling an elevator car, and an elevator system are disclosed. The car panel of the elevator car includes a lower portion, the lower portion attached to a floor of the elevator car and an upper portion, the upper portion attached to a side panel by a hinge. The hinge allows the upper portion to displace, with respect to the lower portion, by rotating the upper portion inwardly about the hinge towards an interior space of the elevator car. Displacement of the upper portion, with respect to the lower portion, from rotating the upper portion inwardly about the hinge provides ingress to a hoistway of the elevator system.

Abstract: A drill system for forming a curved tunnel in a bone includes a drill bit guidance device. The drill bit guidance device includes an elongated stationary outer tube extending along a first axis and an elongated inner tube. The elongated inner tube is configured to slidably move within the elongated stationary outer tube along the first axis and to exit from a distal end of the elongated outer tube. The elongated inner tube has a partially slotted distal end portion including a plurality of semi-cross-sectional slots extending perpendicular to the first axis. Each slot is configured to collapse inward in the slot direction when exiting the distal end of the elongated outer tube, thereby curving the distal end portion of the elongated inner tube.

Abstract: Systems and methods for improved flow properties in fluidic and microfluidic systems are disclosed. The system includes a microfluidic device having a first microchannel, a fluid reservoir having a working fluid and a pressurized gas, a pump in communication with the fluid reservoir to maintain a desired pressure of the pressurized gas, and a fluid-resistance element located within a fluid path between the fluid reservoir and the first microchannel. The fluid-resistance element includes a first fluidic resistance that is substantially larger than a second fluidic resistance associated with the first microchannel.

Abstract: Systems and methods for improved flow properties in fluidic and microfluidic systems are disclosed. The system includes a microfluidic device having a first microchannel, a fluid reservoir having a working fluid and a pressurized gas, a pump in communication with the fluid reservoir to maintain a desired pressure of the pressurized gas, and a fluid-resistance element located within a fluid path between the fluid reservoir and the first microchannel. The fluid-resistance element includes a first fluidic resistance that is substantially larger than a second fluidic resistance associated with the first microchannel.

Abstract: Systems and methods for improved flow properties in fluidic and microfluidic systems are disclosed. The system includes a microfluidic device having a first microchannel, a fluid reservoir having a working fluid and a pressurized gas, a pump in communication with the fluid reservoir to maintain a desired pressure of the pressurized gas, and a fluid-resistance element located within a fluid path between the fluid reservoir and the first microchannel. The fluid-resistance element includes a first fluidic resistance that is substantially larger than a second fluidic resistance associated with the first microchannel.

Abstract: The invention provides a compression device for the limb of a mobile patient. The device includes an inflatable sleeve adapted to surround the limb; a conduit attached to the sleeve for delivering fluid to the sleeve; and a portable, wearable controller attached to the conduit that generates and controls the flow of fluid in the device.

Abstract: The present invention provides a homogenized organic wrapping sheet made from mint-based fiber pulp for smoking articles. The wrapping sheet imparts distinctive properties to the smoking article, including slow burning, and smooth, cool and pleasant experience to smokers. Furthermore, the invention describes a method to manufacture the homogenized wrapping paper and smoking article.

Abstract: A method includes receiving, from a portable recording device, multiple recordings of sounds made by an elevator during operation of the elevator, the multiple recordings generated at different times. The method includes analyzing, by a sound analysis circuit, the multiple recordings generated at the different times to detect changes in an elevator characteristic over time and generating, based on detecting the changes in the elevator characteristic over time, a notification to perform an action on the elevator.

Abstract: A combined guide rail for an elevator system includes a car guide rail portion to guide an elevator car along an elevator car travel path and a counterweight guide rail portion to guide a counterweight of the elevator system along a counterweight travel path. A connecting portion extends from the car guide rail portion to the counterweight guide rail portion. The car guide rail portion, the counterweight guide rail portion and the connecting portion are formed together as a single unitary structure from a single piece of material.

Abstract: The invention provides a compression device for the limb of a mobile patient. The device includes an inflatable sleeve adapted to surround the limb; a conduit attached to the sleeve for delivering fluid to the sleeve; and a portable, wearable controller attached to the conduit that generates and controls the flow of fluid in the device.

Abstract: A polyaxial tool, including an elongate body defining a first end, a second and a longitudinal axis extending therebetween; the elongate body defining a cavity at the first end; a plurality of arcuate gear teeth circumferentially arranged in the cavity and movable with respect to the elongate body; a socket coupled to the housing and coaxial with the plurality of gear teeth; and a handle coupled to the second end, where an angular position of at least one of the elongate body and handle is adjustable with respect to the plurality of gear teeth.