Abstract: A system and related method exchange medical information with a medical management system. The method comprises receiving, using a processor of a code point resolver, from the medical management system, medical text via a network interface. A code point is a single standardized medical terminology code (SMTC) that corresponds to a medical concept contained within the medical text. The method further applies rule-based logic to process the medical text to form a localized mapping of a text portion of the medical text to a plurality of candidate SMTCs (CSMTCs) that are related to at least one metathesaurus concept entity (MCE) in a metathesaurus, and to determines the code point from the CSMTCs. The method transmits, via the network interface, to the medical management system, the code point.

Abstract: A system and related method exchange medical information with a medical management system. The method comprises receiving, using a processor of a code point resolver, from the medical management system, medical text via a network interface. A code point is a single standardized medical terminology code (SMTC) that corresponds to a medical concept contained within the medical text. The method further applies rule-based logic to process the medical text to form a localized mapping of a text portion of the medical text to a plurality of candidate SMTCs (CSMTCs) that are related to at least one metathesaurus concept entity (MCE) in a metathesaurus, and to determines the code point from the CSMTCs. The method transmits, via the network interface, to the medical management system, the code point.

Abstract: Techniques for dynamic visualization of data are provided. A plurality of therapies is received, where each of the plurality of therapies is associated with a respective plurality of guidelines. A guideline tree is generated based on the plurality of therapies, where each leaf node in the guideline tree represents a respective therapy, and where each edge in the guideline tree represents a respective guideline. A visual depiction of the guideline tree is generated. Further, a first plurality of attributes associated with a first patient is received, and a first modified visual depiction of the guideline tree is generated based on the first plurality of attributes.

Abstract: Techniques for granular analysis of a knowledge graph are provided. A profile comprising a plurality of attributes is received, and a knowledge graph is analyzed to identify a plurality of therapies, based on the plurality of attributes. A document that is relevant to a first therapy of the plurality of therapies is identified, and a criterion stated in the document is determined. Further, an aggregate value is determined for the criterion, based on a plurality of participants associated with the document, wherein the first aggregate value represents attributes of the plurality of participants. A weight is generated for the document, based at least in part on the plurality of attributes and the aggregate value. A score is generated for the first therapy, based at least in part on the weight, and an optimal therapy is determined, from the plurality of therapies, based in part on the score.

Abstract: Techniques for identifying missing evidence are provided. A plurality of documents, each comprising digitally encoded natural language text data, is received. The plurality of documents is processed to determine a plurality of pair-wise comparisons between a plurality of therapies, where each of the plurality of pair-wise comparisons indicate a relative efficacy of at least one therapy in the plurality of therapies, as compared to at least one other therapy in the plurality of therapies. A knowledge graph is generated based at least in part on aggregating the plurality of pair-wise comparisons, and the knowledge graph is analyzed to identify one or more knowledge gaps within the knowledge graph. Finally, at least an indication of the identified one or more knowledge gaps is output.

Abstract: Techniques for evaluating dynamically modified plans are provided. A selection of a treatment plan template is received, where the treatment plan template specifies a plurality of treatment stages, where each treatment stage defines a plurality of treatment options. A plurality of modifications to the treatment plan template is generated. It is determined, for each respective modification of the plurality of modifications, whether the respective modification is permissible, based on one or more predefined institutional criteria. Upon determining that a first modification of the plurality of modifications is permissible, a first treatment plan is generated based on the first modification to the treatment plan template. Further, a first predicted efficacy measure is generated for the first treatment plan based on analyzing a knowledge graph. Finally, the first treatment plan is provided, along with at least an indication of the first predicted efficacy measure.

Abstract: Techniques for unbounded therapy evaluation are provided. A request to suggest a potential therapy based on a patient profile is received. A plurality of accepted therapies is determined based on the patient profile, where the plurality of accepted therapies is based on stored definitions obtained from one or more subject matter experts. Next, a plurality of therapy components is identified based on the plurality of accepted therapies. A plurality of potential therapies is then identified based on the plurality of therapy components, where none of the plurality of potential therapies are included in the plurality of accepted therapies. A score is generated for a potential therapy of the plurality of potential therapies based on analyzing a knowledge graph, where the score indicates a suitability of the potential therapy for a patient associated with the patient profile. Finally, the potential therapy is provided, along with an indication of the score.

Abstract: A system and related method exchange medical information with a medical management system. The method comprises receiving, using a processor of a code point resolver, from the medical management system, medical text via a network interface. A code point is a single standardized medical terminology code (SMTC) that corresponds to a medical concept contained within the medical text. The method further applies rule-based logic to process the medical text to form a localized mapping of a text portion of the medical text to a plurality of candidate SMTCs (CSMTCs) that are related to at least one metathesaurus concept entity (MCE) in a metathesaurus, and to determines the code point from the CSMTCs. The method transmits, via the network interface, to the medical management system, the code point.

Abstract: A method includes determining a password-length threshold. The password-length threshold may comprise an integer. The method also includes obtaining, for a first user, a set of nucleotide locations. The number of nucleotide locations in the set may be greater than or equal to the integer. The method also includes obtaining a first sample of the user's DNA. The method also includes determining, in the first sample, a nucleotide at each nucleotide location in the set of nucleotide locations, resulting in a first nucleotide-password sequence. The method also includes performing a one-way hashing operation on the first nucleotide-password sequence with a first hashing algorithm, resulting in a first hashed password.

Abstract: A computer-implemented method, system and computer program product for understanding information using a document analysis technique. An initial corpus of information is formed by identifying a document(s) that match a search criteria. The initial corpus of information is expanded with a set of documents containing statements with a semantic meaning within a threshold degree of similarity to a semantic meaning of statements contained within the document(s) used to form the initial corpus of information. Viewpoint(s) are then extracted from the expanded corpus of information using a natural language processing technique. A new set of documents is analyzed by identifying the subject, assertion and context statements. Assertions in the new set of documents that are within a threshold degree of agreement or disagreement with the extracted viewpoint are highlighted to assist the user in understanding how information aligns with a viewpoint.

Abstract: Techniques for cognitively interpreting comparative statements are provided. A corpus of documents associated with treatment of a first medical disorder is received. Relative efficacies for a plurality of therapies are determined by, for at least a first respective document in the corpus of documents, identifying and extracting, using one or more natural language processing techniques, a conclusion specified within natural language text of the respective document, where the conclusion includes a comparison between two or more therapies of the plurality of therapies, determining a sentiment of the extracted conclusion, with respect to at least one therapy of the plurality of therapies, and identifying one or more cohorts of patients that are associated with the conclusion. A knowledge graph is generated based on the relative efficacies.

Abstract: Techniques for cognitive analysis of documents are provided. A document corresponding to a clinical trial is received. Criteria are identified for the clinical trial based on processing the electronic document using natural language processing (NLP) techniques, where the criteria specify attributes of individuals that are eligible for the trial. Further, the criteria are analyzed using NLP techniques to determine a respective confidence level for each respective criterion, where the confidence level indicates a degree of certainty that the criterion is applicable to the trial. A knowledge graph is generated based at least in part on the clinical trial, where the confidence level assigned to each criterion is included in the knowledge graph for subsequent use. Finally, one or more therapies in the knowledge graph are selected to be recommended, based on a patient profile and the confidence level assigned to each of the criteria.

Abstract: A method of searching a database of medical research for documentation in support of a specific treatment for a patient, the method including: identifying a medical condition; identifying attributes of the patient; searching the database for treatment regimens for the medical condition; scoring identified treatment regimens based on similarity of the attributes of the patient to cohorts treated with the treatment regimens and outcomes; and providing a recommendation for a treatment regimen for the patient based on the attributes of the patient.

Abstract: According to embodiments of the present invention, medical treatment outcomes are simulated. A system receives a request to determine a medical treatment pertaining to a medical condition of a patient. The request is applied to one or more models, via a processor, to simulate outcomes for a plurality of different medical treatments for the medical condition, wherein the one or more models account for impacts of the plurality of different medical treatments on use of medical treatments awaiting future approval. The medical treatment is determined from the simulated outcomes, via a processor, with a desired level of impact on the medical treatments awaiting future approval based on characteristics of the patient. Methods and computer readable media are also provided herein for simulating medical treatment outcomes.

Abstract: A method includes determining a password-length threshold. The password-length threshold may comprise an integer. The method also includes obtaining, for a first user, a set of nucleotide locations. The number of nucleotide locations in the set may be greater than or equal to the integer. The method also includes obtaining a first sample of the user's DNA. The method also includes determining, in the first sample, a nucleotide at each nucleotide location in the set of nucleotide locations, resulting in a first nucleotide-password sequence. The method also includes performing a one-way hashing operation on the first nucleotide-password sequence with a first hashing algorithm, resulting in a first hashed password.

Abstract: A method, computer program product, and computing system device for receiving, at a computing device, a plurality of candidate therapy options, a corpus of therapy data, and a set of therapy recipient cohorts. At least a portion of therapy data may be filtered from the corpus of therapy data based upon, at least in part, the plurality of candidate therapy options and the set of therapy recipient cohorts. A graph may be generated to include a plurality of nodes representative of the plurality of candidate therapy options and a plurality of connections between the plurality of nodes indicating a sentiment factor with respect to the plurality of candidate therapy options based upon, at least in part, the at least a portion of therapy data filtered from the corpus of therapy data. Using the graph, a ranked list of the plurality of candidate therapy options may be generated.

Abstract: A computer-implemented method, system and computer program product for understanding information using a document analysis technique. An initial corpus of information is formed by identifying a document(s) that match a search criteria. The initial corpus of information is expanded with a set of documents containing statements with a semantic meaning within a threshold degree of similarity to a semantic meaning of statements contained within the document(s) used to form the initial corpus of information. Viewpoint(s) are then extracted from the expanded corpus of information using a natural language processing technique. A new set of documents is analyzed by identifying the subject, assertion and context statements. Assertions in the new set of documents that are within a threshold degree of agreement or disagreement with the extracted viewpoint are highlighted to assist the user in understanding how information aligns with a viewpoint.

Abstract: In accordance with some embodiments, a plurality of outcomes are generated and used to create a video presentation of representative outcomes. The video presentation is recorded onto a tangible medium (e.g., DVD or CD-ROM) or otherwise provided to a player (e.g., a player may access the video presentation online). This allows a player to purchase a video presentation of (e.g., predetermined) outcomes in a jurisdiction in which gambling is legal yet view the presentation at the player's convenience (e.g., from any jurisdiction and at any time). A player who purchases such a video presentation may subsequently redeem it for a redemption value associated therewith. In some embodiments, the player may request such outcomes by presenting and/or selecting a session object and/or by interfacing with a tangible medium recording or production device (e.g., on a casino floor).

Abstract: Techniques for cognitive analysis of documents are provided. A document corresponding to a clinical trial is received. Criteria are identified for the clinical trial based on processing the electronic document using natural language processing (NLP) techniques, where the criteria specify attributes of individuals that are eligible for the trial. Further, the criteria are analyzed using NLP techniques to determine a respective confidence level for each respective criterion, where the confidence level indicates a degree of certainty that the criterion is applicable to the trial. A knowledge graph is generated based at least in part on the clinical trial, where the confidence level assigned to each criterion is included in the knowledge graph for subsequent use. Finally, one or more therapies in the knowledge graph are selected to be recommended, based on a patient profile and the confidence level assigned to each of the criteria.