Abstract: Techniques for cognitive analysis of documents are provided. A document corresponding to a clinical trial is received. Criteria are identified for the clinical trial based on processing the electronic document using natural language processing (NLP) techniques, where the criteria specify attributes of individuals that are eligible for the trial. Further, the criteria are analyzed using NLP techniques to determine a respective confidence level for each respective criterion, where the confidence level indicates a degree of certainty that the criterion is applicable to the trial. A knowledge graph is generated based at least in part on the clinical trial, where the confidence level assigned to each criterion is included in the knowledge graph for subsequent use. Finally, one or more therapies in the knowledge graph are selected to be recommended, based on a patient profile and the confidence level assigned to each of the criteria.

Abstract: Techniques for granular analysis of a knowledge graph are provided. A profile comprising a plurality of attributes is received, and a knowledge graph is analyzed to identify a plurality of therapies, based on the plurality of attributes. A document that is relevant to a first therapy of the plurality of therapies is identified, and a criterion stated in the document is determined. Further, an aggregate value is determined for the criterion, based on a plurality of participants associated with the document, wherein the first aggregate value represents attributes of the plurality of participants. A weight is generated for the document, based at least in part on the plurality of attributes and the aggregate value. A score is generated for the first therapy, based at least in part on the weight, and an optimal therapy is determined, from the plurality of therapies, based in part on the score.

Abstract: Techniques for unbounded therapy evaluation are provided. A request to suggest a potential therapy based on a patient profile is received. A plurality of accepted therapies is determined based on the patient profile, where the plurality of accepted therapies is based on stored definitions obtained from one or more subject matter experts. Next, a plurality of therapy components is identified based on the plurality of accepted therapies. A plurality of potential therapies is then identified based on the plurality of therapy components, where none of the plurality of potential therapies are included in the plurality of accepted therapies. A score is generated for a potential therapy of the plurality of potential therapies based on analyzing a knowledge graph, where the score indicates a suitability of the potential therapy for a patient associated with the patient profile. Finally, the potential therapy is provided, along with an indication of the score.

Abstract: Techniques for cognitively interpreting comparative statements are provided. A corpus of documents associated with treatment of a first medical disorder is received. Relative efficacies for a plurality of therapies are determined by, for at least a first respective document in the corpus of documents, identifying and extracting, using one or more natural language processing techniques, a conclusion specified within natural language text of the respective document, where the conclusion includes a comparison between two or more therapies of the plurality of therapies, determining a sentiment of the extracted conclusion, with respect to at least one therapy of the plurality of therapies, and identifying one or more cohorts of patients that are associated with the conclusion. A knowledge graph is generated based on the relative efficacies.

Abstract: A method of searching a database of medical research for documentation in support of a specific treatment for a patient, the method including: identifying a medical condition: identifying attributes of the patient; searching the database for treatment regimens for the medical condition; scoring identified treatment regimens based on similarity of the attributes of the patient to cohorts treated with the treatment regimens and outcomes; and providing a recommendation for a treatment regimen for the patient based on the attributes of the patient.

Abstract: Techniques for evaluating dynamically modified plans are provided. A selection of a treatment plan template is received, where the treatment plan template specifies a plurality of treatment stages, where each treatment stage defines a plurality of treatment options. A plurality of modifications to the treatment plan template is generated. It is determined, for each respective modification of the plurality of modifications, whether the respective modification is permissible, based on one or more predefined institutional criteria. Upon determining that a first modification of the plurality of modifications is permissible, a first treatment plan is generated based on the first modification to the treatment plan template. Further, a first predicted efficacy measure is generated for the first treatment plan based on analyzing a knowledge graph. Finally, the first treatment plan is provided, along with at least an indication of the first predicted efficacy measure.

Abstract: Techniques for dynamic visualization of data are provided. A plurality of therapies is received, where each of the plurality of therapies is associated with a respective plurality of guidelines. A guideline tree is generated based on the plurality of therapies, where each leaf node in the guideline tree represents a respective therapy, and where each edge in the guideline tree represents a respective guideline. A visual depiction of the guideline tree is generated. Further, a first plurality of attributes associated with a first patient is received, and a first modified visual depiction of the guideline tree is generated based on the first plurality of attributes.

Abstract: Techniques for identifying missing evidence are provided. A plurality of documents, each comprising digitally encoded natural language text data, is received. The plurality of documents is processed to determine a plurality of pair-wise comparisons between a plurality of therapies, where each of the plurality of pair-wise comparisons indicate a relative efficacy of at least one therapy in the plurality of therapies, as compared to at least one other therapy in the plurality of therapies. A knowledge graph is generated based at least in part on aggregating the plurality of pair-wise comparisons, and the knowledge graph is analyzed to identify one or more knowledge gaps within the knowledge graph. Finally, at least an indication of the identified one or more knowledge gaps is output.

Abstract: According to embodiments of the present invention, medical treatment outcomes are simulated. A system receives a request to determine a medical treatment pertaining to a medical condition of a patient. The request is applied to one or more models, via a processor, to simulate outcomes for a plurality of different medical treatments for the medical condition, wherein the one or more models account for impacts of the plurality of different medical treatments on use of medical treatments awaiting future approval. The medical treatment is determined from the simulated outcomes, via a processor, with a desired level of impact on the medical treatments awaiting future approval based on characteristics of the patient. Methods and computer readable media are also provided herein for simulating medical treatment outcomes.

Abstract: A method is provided for providing payments at a gaming device, where the payments may occur at predictable times and are of predictable amounts. In one or more embodiments, a gaming device may provide a guaranteed payment every hour on the hour, so long as a player meets one or more criteria. Criteria may include a total amount wagered, a total number of handle pulls completed, or a total amount of time spent at a gaming device. One or more embodiments provide a method for withholding value from a player in order that the value may delivered later in the form of a guaranteed payment. One or more embodiments provide a method whereby multiple gaming devices may provide payments simultaneously, thereby creating mutually reinforcing sounds and visual displays.

Abstract: A method, computer program product, and computing system device for receiving, at a computing device, a plurality of candidate therapy options, a corpus of therapy data, and a set of therapy recipient cohorts. At least a portion of therapy data may be filtered from the corpus of therapy data based upon, at least in part, the plurality of candidate therapy options and the set of therapy recipient cohorts. A graph may be generated to include a plurality of nodes representative of the plurality of candidate therapy options and a plurality of connections between the plurality of nodes indicating a sentiment factor with respect to the plurality of candidate therapy options based upon, at least in part, the at least a portion of therapy data filtered from the corpus of therapy data. Using the graph, a ranked list of the plurality of candidate therapy options may be generated.

Abstract: In accordance with some embodiments, a method provides for determining that a qualifying outcome has been obtained as a result of a game play conducted on a gaming device and determining a buy-in amount for a current play session in which the game play is included. The method further provides for setting, in response to the obtainment of the qualifying outcome, a credit meter balance to the buy-in amount, thereby providing a payout for the qualifying outcome.

Abstract: A method, computer system, and a computer program product for a dynamic question and answer (QA) process is provided. The present invention may include receiving an input by a user. The present invention may also include analyzing a user expertise level and an amount of experience based on the received input. The present invention may then include adjusting an expert recommendation to align with the analyzed user expertise level and the amount of experience based on the analyzed user expertise. The present invention may further include providing a plurality of feedback based on the adjusted expert recommendation.

Abstract: A system to determine offers and/or to determine the acceptability of offers based on received information relating to product redemption at a third party. According to one embodiment, the system includes arrangement for a customer to redeem a product from a third party, reception of information relating to a redemption of the product by the customer, reception of an offer to purchase a product for an offer price, determination to accept the offer based on the received information relating to the redemption, determination of an assigned third party at which the offer product may be redeemed based on the received information, and transmission of an acceptance of the offer and an indication of the assigned third party.

Abstract: An oil spill recovery vessel (10) is provided that comprises a catamaran bow section (12) with twin hulls between which an oil skimmer unit (11) is arranged for displacement between a lowered, operating, position in oil-polluted water and a raised, non-operational, position clear of the water. Aft of the catamaran bow section (12) is a trimaran main section (13) made up of a central hull interposed between two outer hulls formed by aft continuations of the twin hulls of the catamaran bow section (12); the three hulls of the trimaran main section have conjoined upper portions. A propulsion unit (53) is operative to move the vessel (10) forward at slow speed for skimming operations, and, with the skimmer unit (11) in its raised position, at a fast speed in which the vessel planes on its trimaran main section (13).

Abstract: A system to determine offers and/or to determine the acceptability of offers based on received information relating to product redemption at a third party. According to one embodiment, the system includes arrangement for a customer to redeem a product from a third party, reception of information relating to a redemption of the product by the customer, reception of an offer to purchase a product for an offer price, determination to accept the offer based on the received information relating to the redemption, determination of an assigned third party at which the offer product may be redeemed based on the received information, and transmission of an acceptance of the offer and an indication of the assigned third party.

Abstract: An oil spill recovery vessel (10) is provided that comprises a catamaran bow section (12) with twin hulls between which an oil skimmer unit (11) is arranged for displacement between a lowered, operating, position in oil-polluted water and a raised, non-operational, position clear of the water. Aft of the catamaran bow section (12) is a trimaran main section (13) made up of a central hull interposed between two outer hulls formed by aft continuations of the twin hulls of the catamaran bow section (12); the three hulls of the trimaran main section have conjoined upper portions. A propulsion unit (53) is operative to move the vessel (10) forward at slow speed for skimming operations, and, with the skimmer unit (11) in its raised position, at a fast speed in which the vessel planes on its trimaran main section (13).

Abstract: A method is provided for providing payments at a gaming device, where the payments may occur at predictable times and are of predictable amounts. In one or more embodiments, a gaming device may provide a guaranteed payment every hour on the hour, so long as a player meets one or more criteria. Criteria may include a total amount wagered, a total number of handle pulls completed, or a total amount of time spent at a gaming device. One or more embodiments provide a method for withholding value from a player in order that the value may delivered later in the form of a guaranteed payment. One or more embodiments provide a method whereby multiple gaming devices may provide payments simultaneously, thereby creating mutually reinforcing sounds and visual displays.

Abstract: The invention includes a system and method for determining and achieving an optimized rate of play of a gaming device for a given player. The system monitors play at a gaming device, determines whether adjustments to parameters that effect the potential maximum rate of play should be made, and makes the appropriate adjustments. Monitoring play includes measuring such things as force applied to input buttons and tracking unnecessary button presses at inappropriate times (i.e., while the reels are still spinning). Parameters that effect the potential maximum rate of play include reel resolution time, length of bonus displays, payout rate, and the like.

Abstract: A method is provided for providing payments at a gaming device, where the payments may occur at predictable times and are of predictable amounts. In one or more embodiments, a gaming device may provide a guaranteed payment every hour on the hour, so long as a player meets one or more criteria. Criteria may include a total amount wagered, a total number of handle pulls completed, or a total amount of time spent at a gaming device. One or more embodiments provide a method for withholding value from a player in order that the value may delivered later in the form of a guaranteed payment. One or more embodiments provide a method whereby multiple gaming devices may provide payments simultaneously, thereby creating mutually reinforcing sounds and visual displays.