Abstract: Compounds of general formula (I): where A, E, G, X, Y and the bond - - - take various meanings are of use in the preparation of a pharmaceutical formulation, for example in the treatment of a disease in which GSK-3 is involved, including Alzheimer's disease or the non-dependent insulin diabetes mellitus, or hyperproliferative disease such as cancer, displasias or metaplasias of tissue, psoriasis, arteriosclerosis or restenosis.

Abstract: Compounds of formula I: [wherein: X represents —CH═CH—, —CH═CR—, —CR═CR—, —CO—, —O—, —NH—, —NR—, S—, —SO—, —SO2—, —CH═N—, —CR═N—, —CH═N(O)—, —CR═N(O)— or any other atom or group of atoms capable of forming a S— or 6-membered heterocyclic ring; Y1, Y2 and Y3 independently represent hydrogen or halogen; R1, R2 and R3 are independently represent hydrogen, halogen, hydrocarbyl (—R), hydroxyl (—OH), hydrocarbyloxy (—O—R), mercapto (—SH), hydrocarbylthio (—S—R), hydrocarbylsulfinyl (—SO—R), hydrocarbylsulfonyl (—SO2—R), nitro (—NO2), amino (—NH2), hydrocarbylamino (—NHR), bis(hydrocarbyl)amino (—NR2), hydrocarbylcarbonylamino (—NH—CO—R), cyano (—CN), carbamoyl (—CONH2), hy

Abstract: The respective proportions of currency items of different denominations in a multi-denominational store are adjusted in accordance with future change requirements for the different denominations. This is achieved by inhibiting the sending of a particular denomination to the store if the number of currency items of that denomination currently contained in the store exceeds a threshold, leaving more room for currency items of other denominations. There is also disclosed a multi-denominational banknote store which stores banknotes individually in radial regions of a drum, and which can rotate to bring each region into registry with an input/output conveyor.

Abstract: A fluid administration system for the operation of a cylinder and piston assembly for actuating mechanisms, mainly glassware forming and handling mechanisms, allowing rapid changing thereof, comprising: a passage network practiced at the cylinder cap, connected to the fluid admission and discharging passages of the centering ring, at the cylinder and at the support frame; and speed controlling valves, at the passage network of the cylinder cap, to control the velocity of discharging of fluid from the cylinder and piston assembly in its ascending and descending runs.

Abstract: Value carriers are validated according to their suitability for recirculation and routed to a two-way store (16) if suitable or to an escrow (14) if not. The two-way store (16) carries value carriers accepted during previous transactions and dispenses the value carriers it received during the current transaction if the transaction is cancelled. In one embodiment, the escrow (16a, 16b) is another two-way store capable of storing value carriers received during previous transactions, thus removing the need for a dedicated escrow. Moreover, the selection of which two-way store is to act as an escrow may vary from one transaction to the next.

Abstract: Compounds of formula I: 1

Abstract: Compounds of general formula (I): 1

Abstract: A fluid administration system for the operation of a cylinder and piston assembly for actuating mechanisms, mainly glassware forming and handling mechanisms, allowing rapid changing thereof, comprising: a passage network practiced at the cylinder cap, connected to the fluid admission and discharging passages of the centering ring, at the cylinder and at the support frame; and speed controlling valves, at the passage network of the cylinder cap, to control the velocity of discharging of fluid from the cylinder and piston assembly in its ascending and descending runs.

Abstract: A paper guiding device for the discharge of copied original sheets from and mountable on copying machines. Said guiding device comprises first elongated flexible guide means provided with fastening means for mounting adjacent the opening from which the original is discharged, the free end or ends of which extend curvedly and vertically upward and backwardly over portions of the front and top surfaces of the copier; a second elongated shorter guide means mounted along the upper front edge of the copier and extending bidirectionally curvedly thereover, beneath and substantially parallel with a length portion of the first guide means; the original, in being discharged, is caused to move upwardly on and along the first guide means, and then into the passage formed by the overlapping portions of said two guide means and beyond, to the top surface of the copier.