Abstract: Drug conjugates of formula [D-(X)b-(AA)w-(L)-]n-Ab wherein: D is a drug moiety having the following formula (I) or a pharmaceutically acceptable salt, ester, solvate, tautomer or stereoisomer thereof, wherein: A is selected from (II) and (III) R1, R2 and R3 is H, ORa, OCORa, OCO—ORa, alkyl, alkenyl, alkynyl, etc; R3? is, CORa, COORa, CONRaRb, etc; each of R4 to R10 and R12 is alkyl, alkenyl or alkynyl; R11 is H, CORa, COORa, alkyl, alkenyl or alkynyl, or R11 and R12+N+C atoms to which they are attached may form a heterocyclic group; each of R13 and R14 is H, CORa, COORa, alkyl, alkenyl or alkynyl; each Ra and Rb is H, alkyl, alkenyl, alkynyl, etc.

Abstract: An electronic memorial system plays audio and visual information related to a deceased person in order to honor and remember the deceased person. The system includes a grave marker. A display assembly is coupled to the grave marker. The display assembly includes a screen for displaying visual information about a deceased person when the display assembly is activated. A processor is electrically coupled to the display assembly. A speaker is electrically coupled to the processor wherein the speaker emits audio information about the deceased person when the speaker is activated.

Abstract: The invention relates to a machine for assembling boxes of the type that comprise four independent parts, namely: two head walls, two side walls and a base provided with peripheral flanges that engage with grooves provided in the lower portion of the side walls and head walls. In addition, the ends are provided with end tongues that are inserted into notches provided close to the ends of the sides. The machine includes a central assembly station (1) comprising a base ring (10) inside which a stationary forming die (11) is disposed. The base of the box (2) to be formed is positioned on the lower face of the die, such that, while the base is held in position, horizontal push devices are activated which move the head walls (4) and the side walls (3) towards the base (5) which is locked in position against the lower face of the stationary forming die (11).

Abstract: A transgenic plant that overexpresses sucrose synthase. The transgenic plant has a genetic construct that encodes a sucrose synthase peptide.

Abstract: A process for the production of transgenic plants that have a high starch content and yield and a high amylose/amylopectin ratio. The alpha-1,4-glucan phosphorylases (GPs) catalyze the reversible cutting of bonds ?-1,4 of the non-reducing ends of homopolysaccharides with at least 5 glucose molecules such as starch, maltodextrin and glycogen, leading to production of glucose-1-phosphate. The GPs in bacteria and animal cells are responsible for the breakdown of glycogen. Although the increase in GP activity leads to a reduction in intracellular levels of glycogen in bacteria and animal cells, this invention discloses the production of plants that have high starch levels and yields and high amylose/amylopectin ratio, as result of the expression of genes coding for GPs.

Abstract: A gate operator system featuring board display attachment for a lift-gate at the vehicle access control point. The system features board display attached to the lift-gate, which moves in a synchronous motion with the lift gate. At least 3 hooks are placed at an appropriate distance according to the situation where the advertisement boards attach. The attachment takes place by threading the hooks through the perforations located at the top and center of the advertisement boards and locking them in place while allowing them free movement within a 90 degree range. The hooks are placed at different intervals (distances) from the operating mechanism.

Abstract: A vaporizer device of the type which is connected to the electric mains by a plug (1), incorporating a single container (6) equipped with a body of two or more independent receptacles (8) which hold different liquid fragrances in which respective wicks (2) are immersed and a lid (9) which closes the body (7) and renders the receptacles (8) independent. The lid (9) comes with openings (10) in correspondence with the positions of the wicks (2) for the egress and vaporization of the fragrance by actuation of one or more resistance elements (3), located in opposition to the openings (10), either with use of a manual pushbutton (4) or automatically in accordance with a pre-established program, diffusing the fragrances in a sequential or combined manner during predetermined intervals of time.

Abstract: The present invention describes an ocular device comprising a magnetic eye implant and a ferrofluid. The products of the invention solve the problems of the patients' position and contribute to the increase in the success rate of the surgical procedure for correcting retinal detachment, problems of severe proliferative diabetic retinopathy in those incapable of maintaining posture, of infectious retinitis, problems resulting from traumatisms and endophthalmitis. It is also possible to use the device as an auxiliary surgical element, e.g., for extracting subretinal fluid.

Abstract: The invention relates to a method for changing the development pattern, increasing the growth and starch accumulation, changing the structure of starch and increasing the resistance to water stress in plants. The method involves culturing plants in an atmosphere containing volatile elements emitted by a microorganism, without there being any physical contact between the microorganism and the plant. The method is based on the discovery that the volatile elements emitted by Gram-positive or Gram-negative bacteria, yeasts and microscopic fungi stimulate an increase in the growth of plants in general, with an increase in the height, the number of leaves and/or the number of branches of the plant, as well as an increase in the accumulated starch and structural change of this biopolymer, and modification of the development pattern, with an increase in floral buds. An increased resistance to water stress can also be observed, in addition to an increase in starch in leaves separated from whole plants.

Abstract: A transgenic plant that overexpresses sucrose synthase. The transgenic plant has a genetic construct that encodes a sucrose synthase peptide.

Abstract: An isolated sucrose synthase peptide. Also, a method of preparing ADPglucose by incubating the isolated sucrose synthase peptide with ADP in suitable conditions and then isolating and purifying the ADPG produced. Also, an assay kit for the spectrophotometric, fluorimetric or amperometric determination of sucrose, which kit includes the isolated sucrose synthase peptide. Also, a method of producing a transgenic plant that overexpresses sucrose synthase by inserting a genetic construct containing a DNA fragment that encodes the sucrose synthase peptide into a vector and transferring to a plant genome, and a transgenic plant obtained thereby.

Abstract: Process for the production of transgenic plants that have high content and yield of starch and biomass. The starch synthases (SSs) in plants (including SSIV) and glycogen synthase (GlgA) in bacteria catalyse the transfer of the glucosidic part of the ADP-Glucose molecule (the activated donor of glucose) to a pre-existing ?(1, 4)-glucan. However, in contrast to the other SSs, SSIV is able to add glucose units to maltotriose. Also, in contrast to other soluble SSs, SSIV is bound to the starch granule. This invention describes for the first time how to obtain plants that have high levels and yields of starch and biomass as a consequence of the expression of genes coding for SSIV.

Abstract: A process for the production of transgenic plants that have a high starch content and yield and a high amylose/amylopectin ratio. The alpha-1,4-glucan phosphorylases (GPs) catalyze the reversible cutting of bonds ?-1,4 of the non-reducing ends of homopolysaccharides with at least 5 glucose molecules such as starch, maltodextrin and glycogen, leading to production of glucose-1-phosphate. The GPs in bacteria and animal cells are responsible for the breakdown of glycogen. Although the increase in GP activity leads to a reduction in intracellular levels of glycogen in bacteria and animal cells, this invention discloses the production of plants that have high starch levels and yields and high amylose/amylopectin ratio, as result of the expression of genes coding for GPs.

Abstract: The compacted food for animals is made up of the following elements: a) essential oils; b) molasses; c) correctives; d) forage; e) water; f) aromas; g) glucoses; mixed, minced and compacted.

Abstract: Composed of a board display attachment to the access lift-gate, placed close to the lift-gate, with the same dimensions (measurements), moving in synchrony. It has at least 3 hooks placed at an appropriate distance according to the situation where the advertisement boards attach. The attachment takes place by threading the hooks trough the perforations located at the top and center of the advertisement boards; locking them in place while allowing them free movement within a 90 degree range. The hooks are placed at different intervals (distances) from the operating mechanism.

Abstract: It is intended for being able to adapt advertising elements related to the doors in relation to their opening and closing, in such a way that normally, when the door is closed, the advertising is displayed in its entire extent, and when the door is open the advertising is hidden. It is characterized in that it includes means for linking the advertising elements to the door, in such a way that when the door is closed, the advertising is displayed in its entirety in correspondence with the front surface of the door, hiding the same, while when the door is open the advertising elements leave the space for the door free, with the advertising being normally hidden.

Abstract: A system for artificial enhancement of contrast in image visualization may include at least one illumination source that emits short light pulses in a divergent beam, an optical system which forms an output image from the light reflected by objects that have been illuminated, a device which selectively blocks during specific time intervals the output image of the system, and an electronic system for synchronizing the instants of time when the illuminating pulses are emitted as well as when the output images are blocked.

Abstract: Method of production of recombinant sucrose synthase, use thereof in the manufacture of kits for determination of sucrose, production of ADPglucose and production of transgenic plants whose leaves and storage organs accumulate high contents of ADPglucose and starch A method is described for efficient production of large quantities of soluble recombinant SS in its active form, by expression of the gene that encodes SS in a strain of Escherichia coli. The expression vector used means that the recombinant SS produced possesses a histidine tail which facilitates its quick purification. In addition it describes sequences of mutated versions of the gene of SS that encode isoforms of SS suitable for the production of ADPG. Making use of the “wild-type” and “mutated” versions of recombinant SS, an efficient method is described for production of ADPG and UDPG. It also describes the use of SS for the production of assay kits for the determination of sucrose.

Abstract: A base for supporting the weight of a user, tools and a ladder is described. The base can be formed of a plurality of rigid plates, each plate having a top and a bottom side. The plates can be hingedly connected to fold together along a longitudinal axis with the bottom sides of the respective plates being positioned adjacent to each other. The base can include a plurality of wheels positioned around the bottom side and the periphery of each plate. The wheels can be positioned to oppose one another and the opposed wheels being positioned off center from each other when the plates are folded such that the wheels do not interfere with each other, the base when folded is adapted to be stored with the longitudinal axis in a substantially vertical direction.

Abstract: What are disclosed are a purified novel enzyme protein, UGPPase, which naturally occurs in animal cells, its production by means of recombinant technology, an antibody to the enzyme protein, a method of carrying out ELISA for measurement of the amount of UGPPase in an analyte and a method for determination of UDPG in a sample. The one-way enzyme protein catalyses hydrolysis of UDP-glucose, the precursor molecule of glycogen, into glucose-1-phosphate (G1P) and uridine 5?-monophosphate (UMP).